Production of a truncated soluble human semicarbazide-sensitive amine oxidase mediated by a GST-fusion protein secreted from HEK293 cells

Protein Expression and Purification

Volumn 46, Issue 2, 2006, Pages 321-331

  Öhman, Johan ^a,c   Jakobsson, Emma ^b   Källström, Ulla ^a   Elmblad, Annette ^a   Ansari, Akbar ^a   Kalderén, Christina ^a   Robertson, Elinor ^a,d   Danielsson, Eva ^a   Gustavsson, Anna Lena ^a   Varadi, Andrea ^a   Ekblom, Jonas ^a,e   Holmgren, Erik ^a   Doverskog, Magnus ^a   Abrahmsén, Lars ^a,f   Nilsson, Joakim ^a  

^a BIOVITRUM AB   (Sweden)

^b UPPSALA UNIVERSITY   (Sweden)

^c BIACORE AB   (Sweden)

^d ASTRAZENECA R AND D   (Sweden)

^e INVITROGEN CORPORATION   (United States)

^f Affibody AB   (Sweden)

Author keywords

Copper containing amine oxidase; Semicarbazide sensitive amine oxidase; Vascular adhesion protein 1

Indexed keywords

AMINE OXIDASE (COPPER CONTAINING); ENZYME INHIBITOR; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; BIOSYNTHESIS; CELL LINE; CHEMISTRY; CONGESTIVE HEART FAILURE; DIABETES MELLITUS; DRUG ANTAGONISM; DRUG DESIGN; ENZYMOLOGY; GENE DELETION; HUMAN; INFLAMMATION; ISOLATION AND PURIFICATION;

AMINE OXIDASE (COPPER-CONTAINING); AMINO ACID SEQUENCE; CELL LINE; DIABETES MELLITUS; DRUG DESIGN; ENZYME INHIBITORS; GLUTATHIONE TRANSFERASE; HEART FAILURE, CONGESTIVE; HUMANS; INFLAMMATION; RECOMBINANT FUSION PROTEINS; SEQUENCE DELETION;

SCHISTOSOMA JAPONICUM;

EID: 33645394800     PISSN: 10465928     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pep.2005.10.027     Document Type: Article

References (52)

1. F. Buffoni Properties, distribution and physiological role of semicarbazide-sensitive amine oxidases Curr. Top. Pharmacol. 2 1993 33 49
2. G.A. Lyles Mammalian plasma and tissue-bound semicarbazide-sensitive amine oxidases: biochemical, pharmacological and toxicological aspects Int. J. Biochem. Cell Biol. 28 1996 259 274
3. J.P. Klinman The multi-functional topa-quinone copper amine oxidases Biochim. Biophys. Acta. 1647 1-2 2003 131 137
4. J. O'Sullivan, M. Unzeta, J. Healy, M.I. O'Sullivan, G. Davey, and K.F. Tipton Semicarbazide-sensitive amine oxidases: Enzymes with quite a lot to do Neurotoxicology. 25 1-2 2004 303 315
5. P. Mátyus, B. Dajka-Halasz, A. Foldi, N. Haider, D. Barlocco, and K. Magyar Semicarbazide-sensitive amine oxidase: current status and perspectives Curr. Med. Chem. 11 10 2004 1285 1298
6. G. Enrique-Tarancon, L. Marti, N. Morin, J.M. Lizcano, M. Unzeta, L. Sevilla, M. Campst, M. Palacini, X. Testar, C. Carpene, and A. Zorzano Role of semicarbazide-sensitive amine oxidase on glucose transport and GLUT4 recruitment to the cell surface in adipose cells J. Biol. Chem. 273 1998 8025 8032
7. N. Morin, J.M. Lizcano, E. Fontan, L. Marti, F. Smith, P. Rouet, D. Prevot, A. Zorzano, M. Unzeta, and C. Carpene Semicarbazide-sensitive amine oxidase substrates stimulate glucose transport and inhibit lipolysis in human adipocytes J. Pharmacol. Exp. Ther. 297 2001 563 572
8. E. Fontana, J. Boucher, V. Visentin, L. Marti, J.M. Lizcano, X. Testar, and C. Carpene Amine oxidase substrates mimic several of the insulin effects on adipocyte differentiation in 3T3 F442A cells Biochem. J. 356 2001 769 777
9. N. Mercier, M. Moldes, K. El Hadri, and B. Feve Semicarbazide-sensitive amine oxidase activation promotes adipose conversion of 3T3-L1 cells Biochem. J. 358 2001 335 342
10. M. Salmi, and S. Jalkanen VAP-1: an adhesin and an enzyme Trends Immunol. 22 2001 211 216
11. S.D. Langford, M.B. Trent, and P.J. Boor Semicarbazide-sensitive amine oxidase and extracellular matrix deposition by smooth-muscle cells Cardiovasc. Toxicol. 2 2 2002 141 150
12. C. Göktürk, J. Nilsson, J. Nordquist, M. Kristensson, K. Svensson, C. Söderberg, M. Israelson, H. Garpenstrand, M. Sjöquist, L. Oreland, and K. Forsberg-Nilsson Overexpression of semicarbazide-sensitive amine oxidase in smooth muscle cells leads to an abnormal structure of the aortic elastic laminas Am. J. Pathol. 163 5 2003 1921 1928
13. R. Lewinsohn Mammalian monoamine-oxidizing enzymes, with special reference to benzylamine oxidase in human tissues Braz. J. Med. Biol. Res. 17 1984 223 256
14. G. Nakos, and R. Gossrau Light microscopic visualization of semicarbazide-sensitive amine oxidase (benzylamine oxidase) using a cerium method Folia Histochem. Cytobiol. 32 1994 3 10
15. P.H. Yu, D.M. Zuo, and B.A. Davis Characterization of human serum and umbilical artery semicarbazide-sensitive amine oxidase (SSAO). Species heterogeneity and stereoisomeric specificity Biochem. Pharmacol. 47 1994 1055 1059
16. V. Castillo, J.M. Lizcano, J. Visa, and M. Unzeta Semicarbazide-sensitive amine oxidase (SSAO) from human and bovine cerebrovascular tissues: biochemical and immunohistological characterization Neurochem. Int. 33 1998 415 423
17. G.A. Lyles, and R. Pino Properties and functions of tissue-bound semicarbazide-sensitive amine oxidases in isolated cell preparations and cell cultures J. Neural. Transm. Suppl. 52 1998 239 250
18. K. Jaakkola, K. Kaunismäki, S. Tohka, G. Yegutkin, E. Vänttinen, T. Havia, L.J. Pelliniemi, M. Virolainen, S. Jalkanen, and M. Salmi Human vascular adhesion protein-1 in smooth muscle cells Am. J. Pathol. 155 1999 1953 1965
19. N. Morin, J.M. Lizcano, E. Fontana, L. Marti, F. Smih, P. Rouet, D. Prevot, A. Zorzano, M. Unzeta, and C. Carpene Semicarbazide-sensitive amine oxidase substrates stimulate glucose transport and inhibit lipolysis in human adipocytes J. Pharmacol. Exp. Ther. 297 2001 563 572
20. P.H. Yu, and D.M. Zuo Oxidative deamination of methylamine by semicarbazide-sensitive amine oxidase leads to cytotoxic damage in endothelial cells. Possible consequences for diabetes Diabetes 42 1993 594 603
21. R. Kurkijärvi, D.H. Adams, R. Leino, T. Möttönen, S. Jalkanen, and M. Salmi Circulating form of human vascular adhesion protein-1 (VAP-1): Increased serum levels in inflammatory liver diseases J. Immunol. 161 1998 1549 1557
22. A. Abella, S. García-Vicente, N. Viguerie, A. Ros-Baro, M. Camps, M. Palacin, A. Zorzano, and L. Marti Adipocytes release a soluble form of VAP-1/SSAO by a metalloprotease-dependent process and in a regulated manner Diabetologia 47 3 2004 429 438
23. C.M. Stolen, G.G. Yegutkin, R. Kurkijärvi, P. Bono, K. Alitalo, and S. Jalkanen Origins of serum semicarbazide-sensitive amine oxidase Circ. Res. 95 1 2004 50 57
24. F. Boomsma, D.J. van Veldhuisen, P.J. de Kam, A.J. Man in't Veld, A. Mosterd, K.I. Lie, and M.A. Schalekamp Plasma semicarbazide-sensitive amine oxidase is elevated in patients with congestive heart failure Cardiovasc. Res. 33 1997 387 391
25. J. Ekblom Potential therapeutic value of drugs inhibiting semicarbazide-sensitive amine oxidase: vascular cytoprotection in diabetes mellitus Pharmacol. Res. 37 1998 87 92
26. P.H. Yu, S. Wright, E.H. Fan, Z.R. Lun, and D. Gubisne-Harberle Physiological and pathological implications of semicarbazide-sensitive amine oxidase Biochim. Biophys. Acta. 1647 1-2 2003 193 199
27. F. Boomsma, A.H. van den Meiracker, S. Winkel, H.J. Aanstoot, M.R. Batstra, A.J. Man in't Veld, and G.J. Bruining Circulating semicarbazide- sensitive amine oxidase is raised both in type I (insulin-dependent), in type II (non-insulin-dependent) diabetes mellitus and even in childhood type I diabetes at first clinical diagnosis Diabetologia 42 1999 233 237
28. Z. Meszaros, I. Karadi, A. Csanyi, T. Szombathy, L. Romics, and K. Magyar Determination of human serum semicarbazide-sensitive amine oxidase activity: a possible clinical marker of atherosclerosis Eur. J. Drug Metab. Pharmacokinet. 24 1999 299 302
29. B.A. Callingham, A.E. Crosbie, and B.A. Rous Some aspects of the pathophysiology of semicarbazide-sensitive amine oxidase enzymes Prog. Brain Res. 106 1995 305 321
30. M. Salmi, G.G. Yegutkin, R. Lehvonen, K. Koskinen, T. Salminen, and S. Jalkanen A cell surface amine oxidase directly controls lymphocyte migration Immunity 14 3 2001 265 276
31. L.M. Salter-Cid, E. Wang, A.M. O'rourke, A. Miller, H. Gao, L. Huang, A. Garcia, and M.D. Linnik Anti-inflammatory effects of inhibiting the amine oxidase activity of semicarbazide-sensitive amine oxidase J. Pharmacol. Exp. Ther. 315 2 2005 553 562
32. N.J. Morris, A. Ducret, R. Aebersold, S.A. Ross, S.R. Keller, and G.E. Lienhard Membrane amine oxidase cloning and identification as a major protein in the adipocyte plasma membrane J. Biol. Chem. 272 1997 9388 9392
33. D.J. Smith, M. Salmi, P. Bono, J. Hellman, T. Leu, and S. Jalkanen Cloning of vascular adhesion protein 1 reveals a novel multifunctional adhesion molecule J. Exp. Med. 188 1998 17 27
34. T.A. Salminen, D.J. Smith, S. Jalkanen, and M.S. Johnson Structural model of the catalytic domain of an enzyme with cell adhesion activity: human vascular adhesion protein-1 (HVAP-1) D4 domain is an amine oxidase Protein Eng. 11 1998 1195 1204
35. Y. Nymalm, H. Kidron, A. Söderholm, L. Viitanen, K. Kaukonen, M. Pihlavisto, D. Smith, T. Veromaa, T.T. Airenne, M.S. Johnson, and T.A. Salminen Crystallization and preliminary X-ray analysis of the human vascular adhesion protein-1 Acta Crystallogr. D59 2003 1288 1290
36. K. Miyashita, J. Okunishi, R. Utsumi, T. Komano, T. Tamura, and N. Satoh Cleavage specificity of coxsackievirus 3C proteinase for peptide substrate Biosci. Biotechnol. Biochem. 60 1996 705 707
37. Q.M. Wang, R.B. Johnson, G.A. Cox, E.C. Villarreal, and R.J. Loncharich A continuous colorimetric assay for rhinovirus-14 3C protease using peptide p-nitroanilides as substrates Anal. Biochem. 252 1997 238 245
38. T. Tudyka, and A. Skerra Glutathione S-transferase can be used as a C-terminal enzymatically active dimerization module for a recombinant protease inhibitor, and functionally secreted into the periplasm of Escherichia coli Protein Sci. 6 1997 2180 2187
39. B. Nilsson, T. Moks, B. Jansson, L. Abrahmsén, A. Elmblad, E. Holmgren, C. Henrichson, T.A. Jones, and M. Uhlén A synthetic IgG-binding domain based on staphylococcal protein A Protein Eng. 1 2 1987 107 113
40. F.-T.A. Chen, and R.A. Evangelista Profiling glycoprotein N-linked oligosaccharide by capillary electrophoresis Electrophoresis 19 1998 2639 2644
41. A. Guttman, F.-T.A. Chen, R.A. Evangelista, Separation of 1-aminopyrene-3,6,8-trisulfonate-labeled asparagine-linked fetuin glycans by capillary gel electrophoresis, Electrophoresis 17 (1996) 412-417.
42. max shifts and their dependence on pH for the 2-hydrazinopyridine derivatives of two copper amine oxidases J. Mol. Catal. B-Enzym. 8 2000 17 25
43. A. Holt, D.F. Sharman, G.B. Baker, and M.M. Palcic A continuous spectrophotometric assay for monoamine oxidase and related enzymes in tissue homogenates Anal. Biochem. 244 1997 384 392
44. N.M. Hooper, E.H. Karran, and A.J. Turner Membrane protein secretases Biochem J. 321 1997 265 279
45. P. Carter, Site-specific proteolysis of fusion proteins, in: M.R. Ladish, R. Willson, C.C. Painton, S.E. Builder (Eds.) Protein Purification: From Molecular Mechanism to Large-Scale Processes (Am. Chem. Soc. Symp. Ser. No. 427), American Chemical Society, 1990, pp. 181-193.
46. P.A. Walker, L.E. Leong, P.W. Ng, S.H. Tan, S. Waller, D. Murphy, and A.G. Porter Efficient and rapid affinity purification of proteins using recombinant fusion proteases Bio/Technology 12 1994 601 605
47. J.M. Lizcano, K.F. Tipton, and M. Unzeta Purification and characterization of membrane-bound semicarbazide-sensitive amine oxidase (SSAO) from bovine lung Biochem J. 331 Pt 1 1998 69 78
48. E. Jakobsson, J. Nilsson, U. Källström, D. Ogg, and G.J. Kleywegt Crystallization of a truncated soluble human semicarbazide-sensitive amine oxidase Acta Crystallogr. F61 2005 272 278
49. E. Jakobsson, J. Nilsson, D. Ogg, and G.J. Kleywegt Structure of human semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 Acta Crystallogr. D: Biol. Crystallogr. 61 Pt 11 2005 1550 1562
50. J. Nilsson, S. Ståhl, J. Lundeberg, M. Uhlén, and P.Å. Nygren Affinity fusion strategies for detection, purification and immobilization of recombinant proteins Protein Express. Purif. 11 1997 1 16
51. X. Zhang, J. Kim, and W.S. McIntire cDNA sequences of variant forms of human placenta diamine oxidase Biochem. Genet. 33 1995 261 268
52. Y. Imamura, S. Noda, Y. Mashima, J. Kudoh, Y. Oguchi, and N. Shimizu Human retina-specific amine oxidase: genomic structure of the gene (AOC2), alternatively spliced variant, and mRNA expression in retina Genomics 51 1998 293 298