Induction of G2/M phase arrest by squamocin in chronic myeloid leukemia (K562) cells

Life Sciences

Volumn 78, Issue 20, 2006, Pages 2378-2383

  Lu, Mei Chin ^a   Yang, Sheng Huei ^a   Hwang, Shiuh Lin ^b   Lu, Yu Jhang ^a   Lin, Yi Hsiung ^a   Wang, Sen Ren ^b   Wu, Yang Chang ^a   Lin, Shinne Ren ^a  

^a KAOHSIUNG MEDICAL UNIVERSITY   (Taiwan)

^b KAOHSIUNG MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Cyclin; G2 M arrest; K562 cells; Squamocin

Indexed keywords

CYCLIN A; CYCLIN B1; CYCLIN D3; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE INHIBITOR; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLIN E; PROTEIN P21; PROTEIN P27; REGULATOR PROTEIN; SQUAMOCIN;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER GROWTH; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CHRONIC MYELOID LEUKEMIA; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVITY; HUMAN; HUMAN CELL; LEUKEMIA CELL; PROTEIN ANALYSIS; STEADY STATE; UPREGULATION;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; BLOTTING, WESTERN; CDC2 PROTEIN KINASE; CDC25 PHOSPHATASE; CELL CYCLE PROTEINS; CELL DIVISION; DOSE-RESPONSE RELATIONSHIP, DRUG; FLOW CYTOMETRY; FURANS; G2 PHASE; GENE PRODUCTS, REX; HUMANS; K562 CELLS; LACTONES; ONCOGENE PROTEIN P21(RAS);

EID: 33645381493     PISSN: 00243205     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.lfs.2005.09.048     Document Type: Article

References (26)

1. C.Y. Chen, F.R. Chang, H.F. Chiu, M.J. Wu, and Y.C. Wu Aromin-A, an Annonaceous acetogenin from Annona cherimola Phytochemistry 51 1999 429 433
2. O. Coqueret New roles for p21 and p27 cell-cycle inhibitors: a function for each cell compartment? Trends in Cell Biology 13 2003 65 70
3. M. Doree, and S. Galas The cyclin-dependent protein kinases and the control of cell division FASEB Journal 8 1994 1114 1121
4. P. Duret, R. Hocquemiller, J.C. Gantier, and B. Figadere Semisynthesis and cytotoxicity of amino acetogenins and derivatives Bioorganic and Medicinal Chemistry 7 1999 1821 1826
5. Y. Fujimoto, T. Eguchi, K. Kakinuma, N. Ikekawa, M. Sahai, and Y.K. Gupa Squamocin, a new cytotoxic bis-tetrahydrofuran containing acetogenin from Annona squamosa Chemical and Pharmaceutical Bulletin 36 1998 4802 4806
6. K. Fujimoto, R. Hosotani, R. Doi, M. Wada, J.U. Lee, T. Koshiba, Y. Miyamoto, S. Tsuji, S. Nakajima, and M. Imamura Induction of cell-cycle arrest and apoptosis by a novel retinobenzoic-acid derivative, TAC-101, in human pancreatic-cancer cell International Journal of Cancer 81 1999 637 644
7. L. Gamet-Payrastre, P. Li, S. Lumeau, G. Cassar, M.A. Dupont, S. Chevolleau, N. Gasc, J. Tulliez, and F. Terce Sulforaphane, a naturally occurring isothiocyanate, induces cell cycle arrest and apoptosis in HT29 human colon cancer cells Cancer Research 60 2000 1426 1433
8. L.H. Hartwell, and T.A. Weinert Checkpoints: controls that ensure the order of cell cycle events Science 246 1989 629 634
9. J.W. Hyun, G.J. Cheon, H.S. Kim, Y.S. Lee, E.Y. Choi, B.H. Yoon, J.S. Kim, and M.H. Chung Radiation sensitivity depends on OGG1 activity status in human leukemia cell lines Free Radical Biology and Medicine 32 2002 212 220
10. D. Kessel, and Y. Luo Cells in cryptophycin-induced cell-cycle arrest are susceptible to apoptosis Cancer Letters 151 2000 25 29
11. R.W. King, P.K. Jackson, and M.W. Kirschner Mitosis in transition Cell 79 1994 563 571
12. B. Lewin Driving the cell cycle: M phase kinases, its partners, and substrates Cell 61 1990 743 752
13. Y.H. Ling, U. Consoli, C. Tornos, M. Andreeff, and R. Perez-Soler Accumulation of cyclin B1, activation of cyclin B1-dependent kinase and induction of programmed cell death in human epidermoid carcinoma KB cells treated with taxol International Journal of Cancer 75 1998 925 932
14. R.B. Lock, and W.E. Ross Inhibition of p34cdc2 kinase activity by etoposide or irradiation as a mechanism of G2 arrest in Chinese hamster ovary cells Cancer Research 50 1990 3761 3766
15. M. Molinari Cell cycle checkpoints and their inactivation in human cancer Cell Proliferation 33 2000 261 274
16. A.W. Murray Revisiting the cell cycle: cyclins revisited Cell 116 2004 221 234
17. P.M. O'Connor, D.K. Ferris, M. Pagano, G. Draetta, J. Pines, T. Hunter, D.L. Longo, and K.W. Kohn G2 delay induced by nitrogen mustard in human cells affects cyclin A/cdk2, and cyclin B1/cdc-2 kinase complexes differently Journal of Biological Chemistry 268 1993 8298 8308
18. D.K. Orren, L.N. Petersen, and V.A. Bohr Persistent DNA damage inhibits S-phase and G2 progression, and results in apoptosis Molecular Biology of the Cell 8 1997 1129 1142
19. E.F. Queiroz, F. Roblot, P. Duret, B. Figad, A. Gouyette, O. Lapreote, L. Serani, and R. Hocquemiller Synthesis, spectroscopy, and cytotoxicity of glycosylated acetogenin derivatives as promising molecules for cancer therapy Journal of Medicinal Chemistry 43 2000 1604 1610
20. S. Raynaud, F. Nemati, L. Miccoli, P. Michel, M.F. Poupon, C. Fourneau, A. Laurens, and R. Hocquemiller Antitumoral effects of squamocin on parental and multidrug resistant MCF7 (human breast adenocarcinoma) cell lines Life Sciences 65 1999 525 533
21. C.J. Sherr Cancer cell cycles Science 274 1996 1672 1677
22. R.J. Sleiman, D.R. Catchpoole, and B.W. Stewart Drug-induced death of leukaemic cells after G2/M arrest: higher order DNA fragmentation as an indicator of mechanism British Journal of Cancer 77 1998 40 50
23. + T lymphocytes Toxicology and Applied Pharmacology 193 2003 97 105
24. K. Torres, and S.B. Horwitz Mechanisms of taxol-induced cell death are concentration dependent Cancer Research 58 1998 3620 3626
25. T. Wada, and J.M. Penninger Mitogen-activated protein kinases in apoptosis regulation Oncogene 23 2004 2838 2849
26. X.F. Zhu, Z.C. Liu, B.F. Xie, Z.M. Li, G.K. Feng, H.H. Xie, S.J. Wu, R.Z. Yang, X.Y. Wei, and Y.X. Zeng Involvement of caspase-3 activation in squamocin-induced apoptosis in leukemia cell line HL-60 Life Sciences 70 2002 1259 1269