메뉴 건너뛰기




Volumn 136, Issue 9-10, 2006, Pages 139-144

The relationship between inflammation and the coagulation system

Author keywords

Coagulation; Fibrinolysis; Infection; Inflammation; Innate immunity

Indexed keywords

ACTIVATED PROTEIN C; BLOOD CLOTTING FACTOR 10A; BLOOD CLOTTING FACTOR 7; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 8; MACROPHAGE MIGRATION INHIBITION FACTOR; MONOCYTE CHEMOTACTIC PROTEIN 1; PLASMINOGEN ACTIVATOR INHIBITOR 1; PROTEINASE; PROTEINASE ACTIVATED RECEPTOR; THROMBIN; THROMBOPLASTIN; TISSUE FACTOR PATHWAY INHIBITOR; TUMOR NECROSIS FACTOR ALPHA;

EID: 33645325388     PISSN: 14247860     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Short Survey
Times cited : (63)

References (65)
  • 1
    • 0033584457 scopus 로고    scopus 로고
    • Disseminated intravascular coagulation
    • Levi M, Ten Cate H. Disseminated intravascular coagulation. N Engl J Med 1999;341:586-92.
    • (1999) N Engl J Med , vol.341 , pp. 586-592
    • Levi, M.1    Ten Cate, H.2
  • 2
    • 0033820789 scopus 로고    scopus 로고
    • Phylogenetic and functional relationships between coagulation and the innate immune response
    • Opal SM. Phylogenetic and functional relationships between coagulation and the innate immune response. Crit Care Med 2000;28:S77-S80.
    • (2000) Crit Care Med , vol.28
    • Opal, S.M.1
  • 3
    • 0031756985 scopus 로고    scopus 로고
    • Tissue factor expression by monocytes: Regulation and pathophysiological roles
    • Østerud B. Tissue factor expression by monocytes: regulation and pathophysiological roles. Blood Coagul Fibrinolysis 1998;9 (Suppl 1):S9-14.
    • (1998) Blood Coagul Fibrinolysis , vol.9 , Issue.SUPPL. 1
    • Østerud, B.1
  • 5
    • 11144248088 scopus 로고    scopus 로고
    • Macrovascular thrombosis is driven by tissue factor derived primarily from the blood vessel wall
    • Day SM, Reeve JL, Pedersen B, Farris DM, Myers DD, Im M, et al. Macrovascular thrombosis is driven by tissue factor derived primarily from the blood vessel wall. Blood 2005;105:192-8.
    • (2005) Blood , vol.105 , pp. 192-198
    • Day, S.M.1    Reeve, J.L.2    Pedersen, B.3    Farris, D.M.4    Myers, D.D.5    Im, M.6
  • 6
    • 8644222225 scopus 로고    scopus 로고
    • Hematopoietic cell-derived microparticle tissue factor contributes to fibrin formation during thrombus propagation
    • Chou J, Mackman N, Merrill-Skoloff G, Pedersen B, Furie BC, Furie B. Hematopoietic cell-derived microparticle tissue factor contributes to fibrin formation during thrombus propagation. Blood 2004;104:3190-7.
    • (2004) Blood , vol.104 , pp. 3190-3197
    • Chou, J.1    Mackman, N.2    Merrill-Skoloff, G.3    Pedersen, B.4    Furie, B.C.5    Furie, B.6
  • 8
    • 9144262380 scopus 로고    scopus 로고
    • Active tissue factor in blood?
    • Butenas S, Mann KG. Active tissue factor in blood? Nat Med 2004;10:1155-6.
    • (2004) Nat Med , vol.10 , pp. 1155-1156
    • Butenas, S.1    Mann, K.G.2
  • 9
    • 0028006127 scopus 로고
    • Inhibition of endotoxin-induced activation of coagulation and fibrinolysis by pentoxifylline or by a monoclonal anti-tissue factor antibody in chimpanzees
    • Levi M, Ten Cate H, Bauer KA, van der Poll T, Edgington TS, Büller HR, et al. Inhibition of endotoxin-induced activation of coagulation and fibrinolysis by pentoxifylline or by a monoclonal anti-tissue factor antibody in chimpanzees. J Clin Invest 1994;93:114-20.
    • (1994) J Clin Invest , vol.93 , pp. 114-120
    • Levi, M.1    Ten Cate, H.2    Bauer, K.A.3    Van Der Poll, T.4    Edgington, T.S.5    Büller, H.R.6
  • 11
    • 0028895452 scopus 로고
    • Complete inhibition of endotoxin-induced coagulation activation in chimpanzees with a monoclonal Fab fragment against factor VII/VIIa
    • Biemond BJ, Levi M, Ten Gate H, Soule HR, Morris LD, Foster DL, et al. Complete inhibition of endotoxin-induced coagulation activation in chimpanzees with a monoclonal Fab fragment against factor VII/VIIa. Thromb Haemost 1995;73:223-30.
    • (1995) Thromb Haemost , vol.73 , pp. 223-230
    • Biemond, B.J.1    Levi, M.2    Ten Gate, H.3    Soule, H.R.4    Morris, L.D.5    Foster, D.L.6
  • 12
    • 0842328843 scopus 로고    scopus 로고
    • Role of tissue factor and protease-activated receptors in a mouse model of endotoxemia
    • Pawlinski R, Pedersen B, Schabbauer G, Tencati M, Holscher T, Boisvert W, et al. Role of tissue factor and protease-activated receptors in a mouse model of endotoxemia. Blood 2004;103:1342-7.
    • (2004) Blood , vol.103 , pp. 1342-1347
    • Pawlinski, R.1    Pedersen, B.2    Schabbauer, G.3    Tencati, M.4    Holscher, T.5    Boisvert, W.6
  • 14
    • 0027953316 scopus 로고
    • Differential effects of anti-tumor necrosis factor monoclonal antibodies on systemic inflammatory responses in experimental endotoxemia in chimpanzees
    • van der Poll T, Levi M, van Deventer SJ, Ten Cate H, Haagmans BL, Biemond BJ, et al. Differential effects of anti-tumor necrosis factor monoclonal antibodies on systemic inflammatory responses in experimental endotoxemia in chimpanzees. Blood 1994;83:446-51.
    • (1994) Blood , vol.83 , pp. 446-451
    • Van Der Poll, T.1    Levi, M.2    Van Deventer, S.J.3    Ten Cate, H.4    Haagmans, B.L.5    Biemond, B.J.6
  • 16
    • 0028323245 scopus 로고
    • Elimination of interleukin 6 attenuates coagulation activation in experimental endotoxemia in chimpanzees
    • van der Poll T, Levi M, Hack CE, Ten Cate H, van Deventer SJ, Eerenberg AJ, et al. Elimination of interleukin 6 attenuates coagulation activation in experimental endotoxemia in chimpanzees. J Exp Med 1994;179:1253-9.
    • (1994) J Exp Med , vol.179 , pp. 1253-1259
    • Van Der Poll, T.1    Levi, M.2    Hack, C.E.3    Ten Cate, H.4    Van Deventer, S.J.5    Eerenberg, A.J.6
  • 17
    • 0026534242 scopus 로고
    • Septic shock, multiple organ failure, and disseminated intravascular coagulation. Compared patterns of anti-thrombin III, protein C, and protein S deficiencies
    • Fourrier F, Chopin C, Goudemand J, Hendrycx S, Caron C, Rime A, et al. Septic shock, multiple organ failure, and disseminated intravascular coagulation. Compared patterns of anti-thrombin III, protein C, and protein S deficiencies. Chest 1992;101:816-23.
    • (1992) Chest , vol.101 , pp. 816-823
    • Fourrier, F.1    Chopin, C.2    Goudemand, J.3    Hendrycx, S.4    Caron, C.5    Rime, A.6
  • 18
    • 0029743427 scopus 로고    scopus 로고
    • Factor VIIa and antithrombin III activity during severe sepsis and septic shock in neutropenic patients
    • Mesters RM, Mannucci PM, Coppola R, Keller T, Ostermann H, Kienast J. Factor VIIa and antithrombin III activity during severe sepsis and septic shock in neutropenic patients. Blood 1996;88:881-6.
    • (1996) Blood , vol.88 , pp. 881-886
    • Mesters, R.M.1    Mannucci, P.M.2    Coppola, R.3    Keller, T.4    Ostermann, H.5    Kienast, J.6
  • 19
    • 0024589205 scopus 로고
    • Tumor necrosis factor leads to the internalization and degradation of thrombomodulin from the surface of bovine aortic endothelial cells in culture
    • Moore KL, Esmon CT, Esmon NL. Tumor necrosis factor leads to the internalization and degradation of thrombomodulin from the surface of bovine aortic endothelial cells in culture. Blood 1989;73:159-65.
    • (1989) Blood , vol.73 , pp. 159-165
    • Moore, K.L.1    Esmon, C.T.2    Esmon, N.L.3
  • 21
    • 0022601049 scopus 로고
    • Modulation of endothelial cell hemostatic properties by tumor necrosis factor
    • Nawroth PP, Stern DM. Modulation of endothelial cell hemostatic properties by tumor necrosis factor. J Exp Med 1986;163:740-5.
    • (1986) J Exp Med , vol.163 , pp. 740-745
    • Nawroth, P.P.1    Stern, D.M.2
  • 22
    • 2442724586 scopus 로고
    • Interleukin 1 induces endothelial cell procoagulant while suppressing cell-surface anticoagulant activity
    • Nawroth PP, Handley DA, Esmon CT, Stern DM. Interleukin 1 induces endothelial cell procoagulant while suppressing cell-surface anticoagulant activity. Proc Natl Acad Sci USA 1986;83:3460-4.
    • (1986) Proc Natl Acad Sci USA , vol.83 , pp. 3460-3464
    • Nawroth, P.P.1    Handley, D.A.2    Esmon, C.T.3    Stern, D.M.4
  • 24
    • 0026559504 scopus 로고
    • Anticoagulant and fibrinolytic activities are promoted, not retarded, in vivo after thrombin generation in the presence of a monoclonal antibody that inhibits activation of protein C
    • Taylor FB Jr, Hoogendoorn H, Chang AC, Peer G, Nesheim ME, Catlett R, et al. Anticoagulant and fibrinolytic activities are promoted, not retarded, in vivo after thrombin generation in the presence of a monoclonal antibody that inhibits activation of protein C. Blood 1992;79:1720-8.
    • (1992) Blood , vol.79 , pp. 1720-1728
    • Taylor Jr., F.B.1    Hoogendoorn, H.2    Chang, A.C.3    Peer, G.4    Nesheim, M.E.5    Catlett, R.6
  • 27
    • 0026078837 scopus 로고
    • Depletion of extrinsic pathway inhibitor (EPI) sensitizes rabbits to disseminated intravascular coagulation induced with tissue factor: Evidence supporting a physiologic role for EPI as a natural anticoagulant
    • Sandset PM, Warn-Cramer BJ, Rao LV, Maki SL, Rapaport SI. Depletion of extrinsic pathway inhibitor (EPI) sensitizes rabbits to disseminated intravascular coagulation induced with tissue factor: evidence supporting a physiologic role for EPI as a natural anticoagulant. Proc Natl Acad Sci U S A 1991;88:708-12.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 708-712
    • Sandset, P.M.1    Warn-Cramer, B.J.2    Rao, L.V.3    Maki, S.L.4    Rapaport, S.I.5
  • 29
    • 0035146571 scopus 로고    scopus 로고
    • The activity of tissue factor pathway inhibitor in experimental models of super-antigen-induced shock and polymicrobial intra-abdominal sepsis
    • Opal SM, Palardy JE, Parejo NA, Creasey AA. The activity of tissue factor pathway inhibitor in experimental models of super-antigen-induced shock and polymicrobial intra-abdominal sepsis. Crit Care Med 2001;29:13-7.
    • (2001) Crit Care Med , vol.29 , pp. 13-17
    • Opal, S.M.1    Palardy, J.E.2    Parejo, N.A.3    Creasey, A.A.4
  • 30
    • 0031934850 scopus 로고    scopus 로고
    • Delayed treatment with recombinant human tissue factor pathway inhibitor improves survival in rabbits with gram-negative peritonitis
    • Camerota AJ, Creasey AA, Patla V, Larkin VA, Fink MP. Delayed treatment with recombinant human tissue factor pathway inhibitor improves survival in rabbits with gram-negative peritonitis. J Infect Dis 1998;177:668-76.
    • (1998) J Infect Dis , vol.177 , pp. 668-676
    • Camerota, A.J.1    Creasey, A.A.2    Patla, V.3    Larkin, V.A.4    Fink, M.P.5
  • 31
    • 4444314278 scopus 로고    scopus 로고
    • Inhibition of intravascular thrombosis in murine endotoxemia by targeted expression of hirudin and tissue factor pathway inhibitor analogs to activated endothelium
    • Chen D, Giannopoulos K, Shiels PG, Webster Z, McVey JH, Kemball-Cook G, et al. Inhibition of intravascular thrombosis in murine endotoxemia by targeted expression of hirudin and tissue factor pathway inhibitor analogs to activated endothelium. Blood 2004;104:1344-9.
    • (2004) Blood , vol.104 , pp. 1344-1349
    • Chen, D.1    Giannopoulos, K.2    Shiels, P.G.3    Webster, Z.4    McVey, J.H.5    Kemball-Cook, G.6
  • 32
    • 18844480902 scopus 로고    scopus 로고
    • Tissue factor pathway inhibitor dose-dependently inhibits coagulation activation without influencing the fibrinolytic and cytokine response during human endotoxemia
    • de Jonge E, Dekkers PE, Creasey AA, Hack CE, Paulson SK, Karim A, et al. Tissue factor pathway inhibitor dose-dependently inhibits coagulation activation without influencing the fibrinolytic and cytokine response during human endotoxemia. Blood 2000;95:1124-9.
    • (2000) Blood , vol.95 , pp. 1124-1129
    • De Jonge, E.1    Dekkers, P.E.2    Creasey, A.A.3    Hack, C.E.4    Paulson, S.K.5    Karim, A.6
  • 33
    • 0038690407 scopus 로고    scopus 로고
    • Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: A randomized controlled trial
    • Abraham E, Reinhart K, Opal S, Demeyer I, Doig C, Rodriguez AL, et al. Efficacy and safety of tifacogin (recombinant tissue factor pathway inhibitor) in severe sepsis: a randomized controlled trial. JAMA 2003;290:238-47.
    • (2003) JAMA , vol.290 , pp. 238-247
    • Abraham, E.1    Reinhart, K.2    Opal, S.3    Demeyer, I.4    Doig, C.5    Rodriguez, A.L.6
  • 34
    • 15244349532 scopus 로고    scopus 로고
    • Regulation of tissue factor-induced signaling by endogenous and recombinant tissue factor pathway inhibitor 1
    • Ahamed J, Belting M, Ruf W. Regulation of tissue factor-induced signaling by endogenous and recombinant tissue factor pathway inhibitor 1. Blood 2005;105:2384-91.
    • (2005) Blood , vol.105 , pp. 2384-2391
    • Ahamed, J.1    Belting, M.2    Ruf, W.3
  • 36
    • 0029041753 scopus 로고
    • Plasminogen activator and plasminogen activator inhibitor I release during experimental endotoxaemia in chimpanzees: Effect of interventions in the cytokine and coagulation cascades
    • Biemond BJ, Levi M, Ten Cate H, van der Poll T, Büller HR, Hack CE, et al. Plasminogen activator and plasminogen activator inhibitor I release during experimental endotoxaemia in chimpanzees: effect of interventions in the cytokine and coagulation cascades. Clin Sci (Lond) 1995;88:587-94.
    • (1995) Clin Sci (Lond) , vol.88 , pp. 587-594
    • Biemond, B.J.1    Levi, M.2    Ten Cate, H.3    Van Der Poll, T.4    Büller, H.R.5    Hack, C.E.6
  • 37
    • 0025949379 scopus 로고
    • Regulation of murine type 1 plasminogen activator inhibitor gene expression in vivo. Tissue specificity and induction by lipopolysaccharide, tumor necrosis factor-alpha, and transforming growth factor-beta
    • Sawdey MS, Loskutoff DJ. Regulation of murine type 1 plasminogen activator inhibitor gene expression in vivo. Tissue specificity and induction by lipopolysaccharide, tumor necrosis factor-alpha, and transforming growth factor-beta. J Clin Invest 1991;88:1346-53.
    • (1991) J Clin Invest , vol.88 , pp. 1346-1353
    • Sawdey, M.S.1    Loskutoff, D.J.2
  • 38
    • 0034648757 scopus 로고    scopus 로고
    • Thrombin signalling and protease-activated receptors
    • Coughlin SR. Thrombin signalling and protease-activated receptors. Nature 2000;407:258-64.
    • (2000) Nature , vol.407 , pp. 258-264
    • Coughlin, S.R.1
  • 39
    • 0036464689 scopus 로고    scopus 로고
    • Roles for thrombin and fibrin(ogen) in cytokine/chemokine production and macrophage adhesion in vivo
    • Szaba FM, Smiley ST. Roles for thrombin and fibrin(ogen) in cytokine/chemokine production and macrophage adhesion in vivo. Blood 2002;99:1053-9.
    • (2002) Blood , vol.99 , pp. 1053-1059
    • Szaba, F.M.1    Smiley, S.T.2
  • 40
    • 0036533649 scopus 로고    scopus 로고
    • Activation of protease-activated receptor (PAR)-1, PAR-2, and PAR-4 stimulates IL-6, IL-8, and prostaglandin E2 release from human respiratory epithelial cells
    • Asokananthan N, Graham PT, Fink J, Knight DA, Bakker AJ, McWilliam AS, et al. Activation of protease-activated receptor (PAR)-1, PAR-2, and PAR-4 stimulates IL-6, IL-8, and prostaglandin E2 release from human respiratory epithelial cells. J Immunol 2002;168:3577-85.
    • (2002) J Immunol , vol.168 , pp. 3577-3585
    • Asokananthan, N.1    Graham, P.T.2    Fink, J.3    Knight, D.A.4    Bakker, A.J.5    McWilliam, A.S.6
  • 42
    • 1842791473 scopus 로고    scopus 로고
    • Macrophage migration inhibitory factor is induced by thrombin and factor Xa in endothelial cells
    • Shimizu T, Nishihira J, Watanabe H, Abe R, Honda A, Ishibashi T, et al. Macrophage migration inhibitory factor is induced by thrombin and factor Xa in endothelial cells. J Biol Chem 2004;279:13729-37.
    • (2004) J Biol Chem , vol.279 , pp. 13729-13737
    • Shimizu, T.1    Nishihira, J.2    Watanabe, H.3    Abe, R.4    Honda, A.5    Ishibashi, T.6
  • 43
    • 0032525041 scopus 로고    scopus 로고
    • Potential mechanisms for a proinflammatory vascular cytokine response to coagulation activation
    • Johnson K, Choi Y, DeGroot E, Samuels I, Creasey A, Aarden L. Potential mechanisms for a proinflammatory vascular cytokine response to coagulation activation. J Immunol 1998;160:5130-5.
    • (1998) J Immunol , vol.160 , pp. 5130-5135
    • Johnson, K.1    Choi, Y.2    DeGroot, E.3    Samuels, I.4    Creasey, A.5    Aarden, L.6
  • 44
    • 0033136318 scopus 로고    scopus 로고
    • Thrombin-induced p65 homodimer binding to downstream NF-kappa B site of the promoter mediates endothelial ICAM-1 expression and neutrophil adhesion
    • Rahman A, Anwar KN, True AL, Malik AB. Thrombin-induced p65 homodimer binding to downstream NF-kappa B site of the promoter mediates endothelial ICAM-1 expression and neutrophil adhesion. J Immunol 1999;162:5466-76.
    • (1999) J Immunol , vol.162 , pp. 5466-5476
    • Rahman, A.1    Anwar, K.N.2    True, A.L.3    Malik, A.B.4
  • 45
    • 0034624973 scopus 로고    scopus 로고
    • Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIla
    • Camerer E, Huang W, Coughlin SR. Tissue factor- and factor X-dependent activation of protease-activated receptor 2 by factor VIIa. Proc Natl Acad Sci U S A 2000;97:5255-60.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 5255-5260
    • Camerer, E.1    Huang, W.2    Coughlin, S.R.3
  • 46
    • 0035874536 scopus 로고    scopus 로고
    • Gene induction by coagulation factor Xa is mediated by activation of protease-activated receptor 1
    • Riewald M, Kravchenko VV, Petrovan RJ, O'Brien PJ, Brass LF, Ulevitch RJ, et al. Gene induction by coagulation factor Xa is mediated by activation of protease-activated receptor 1. Blood 2001;97:3109-16.
    • (2001) Blood , vol.97 , pp. 3109-3116
    • Riewald, M.1    Kravchenko, V.V.2    Petrovan, R.J.3    O'Brien, P.J.4    Brass, L.F.5    Ulevitch, R.J.6
  • 47
    • 0033571257 scopus 로고    scopus 로고
    • Tissue factor and factor VIIa receptor/ligand interactions induce proinflammatory effects in macrophages
    • Cunningham MA, Romas P, Hutchinson P, Holdsworth SR, Tipping PG. Tissue factor and factor VIIa receptor/ligand interactions induce proinflammatory effects in macrophages. Blood 1999;94:3413-20.
    • (1999) Blood , vol.94 , pp. 3413-3420
    • Cunningham, M.A.1    Romas, P.2    Hutchinson, P.3    Holdsworth, S.R.4    Tipping, P.G.5
  • 48
    • 0038633316 scopus 로고    scopus 로고
    • Activation of coagulation by administration of recombinant factor VIIa elicits interleukin 6 (IL-6) and IL-8 release in healthy human subjects
    • de Jonge E, Friederich PW, Vlasuk GP, Rote WE, Vroom MB, Levi M, et al. Activation of coagulation by administration of recombinant factor VIIa elicits interleukin 6 (IL-6) and IL-8 release in healthy human subjects. Clin Diagn Lab Immunol 2003;10:495-7.
    • (2003) Clin Diagn Lab Immunol , vol.10 , pp. 495-497
    • De Jonge, E.1    Friederich, P.W.2    Vlasuk, G.P.3    Rote, W.E.4    Vroom, M.B.5    Levi, M.6
  • 49
    • 1842547895 scopus 로고    scopus 로고
    • Treatment effects of drotrecogin alfa (activated) in patients with severe sepsis with or without overt disseminated intravascular coagulation
    • DhainautJF, Yan SB, Joyce DE, Petilla V, Basson B, Brandt JT, et al. Treatment effects of drotrecogin alfa (activated) in patients with severe sepsis with or without overt disseminated intravascular coagulation. J Thromb Haemost 2004;2:1924-33.
    • (2004) J Thromb Haemost , vol.2 , pp. 1924-1933
    • Dhainaut, J.F.1    Yan, S.B.2    Joyce, D.E.3    Petilla, V.4    Basson, B.5    Brandt, J.T.6
  • 50
    • 1842738294 scopus 로고    scopus 로고
    • Mechanisms of action of activated protein C: An evolving story
    • van der Poll T, Levi M. Mechanisms of action of activated protein C: an evolving story. Crit Care Med 2004;32:1086-7.
    • (2004) Crit Care Med , vol.32 , pp. 1086-1087
    • Van Der Poll, T.1    Levi, M.2
  • 51
    • 0030034186 scopus 로고    scopus 로고
    • Activated protein C attenuates endotoxin-induced pulmonary vascular injury by inhibiting activated leukocytes in rats
    • Murakami K, Okajima K, Uchiba M, Johno M, Nakagaki T, Okabe H, et al. Activated protein C attenuates endotoxin-induced pulmonary vascular injury by inhibiting activated leukocytes in rats. Blood 1996;87:642-7.
    • (1996) Blood , vol.87 , pp. 642-647
    • Murakami, K.1    Okajima, K.2    Uchiba, M.3    Johno, M.4    Nakagaki, T.5    Okabe, H.6
  • 53
    • 10244229104 scopus 로고    scopus 로고
    • Recombinant human activated protein C reduces human endotoxin-induced pulmonary inflammation via inhibition of neutrophil chemotaxis
    • Nick JA, Coldren CD, Geraci MW, Poch KR, Fouty BW, O'Brien J, et al. Recombinant human activated protein C reduces human endotoxin-induced pulmonary inflammation via inhibition of neutrophil chemotaxis. Blood 2004;104:3878-85.
    • (2004) Blood , vol.104 , pp. 3878-3885
    • Nick, J.A.1    Coldren, C.D.2    Geraci, M.W.3    Poch, K.R.4    Fouty, B.W.5    O'Brien, J.6
  • 54
    • 13444303827 scopus 로고    scopus 로고
    • Activated protein C improves the visceral microcirculation by attenuating the leukocyte-endothelial interaction in a rat lipopolysaccharide model
    • Iba T, Kidokoro A, Fukunaga M, Nagakari K, Shirahama A, Ida Y. Activated protein C improves the visceral microcirculation by attenuating the leukocyte-endothelial interaction in a rat lipopolysaccharide model. Crit Care Med 2005;33:368-72.
    • (2005) Crit Care Med , vol.33 , pp. 368-372
    • Iba, T.1    Kidokoro, A.2    Fukunaga, M.3    Nagakari, K.4    Shirahama, A.5    Ida, Y.6
  • 55
    • 18644373364 scopus 로고    scopus 로고
    • Activated protein C inhibits local coagulation after intrapulmonary delivery of endotoxin in humans
    • van der Poll T, Levi M, Nick JA, Abraham E. Activated Protein C Inhibits Local Coagulation after Intrapulmonary Delivery of Endotoxin in Humans. Am J Respir Crit Care Med 2005;171:1125-8.
    • (2005) Am J Respir Crit Care Med , vol.171 , pp. 1125-1128
    • Van Der Poll, T.1    Levi, M.2    Nick, J.A.3    Abraham, E.4
  • 56
    • 0036250817 scopus 로고    scopus 로고
    • Recombinant human activated protein C attenuates the inflammatory response in endothelium and monocytes by modulating nuclear factor-kappaB
    • Joyce DE, Grinnell BW. Recombinant human activated protein C attenuates the inflammatory response in endothelium and monocytes by modulating nuclear factor-kappaB. Crit Care Med 2002;30:S288-S293.
    • (2002) Crit Care Med , vol.30
    • Joyce, D.E.1    Grinnell, B.W.2
  • 57
    • 0035815747 scopus 로고    scopus 로고
    • Gene expression profile of antithrombotic protein c defines new mechanisms modulating inflammation and apoptosis
    • Joyce DE, Gelbert L, Ciaccia A, DeHoff B, Grinnell BW. Gene expression profile of antithrombotic protein c defines new mechanisms modulating inflammation and apoptosis. J Biol Chem 2001;276:11199-203.
    • (2001) J Biol Chem , vol.276 , pp. 11199-11203
    • Joyce, D.E.1    Gelbert, L.2    Ciaccia, A.3    Dehoff, B.4    Grinnell, B.W.5
  • 58
    • 0027998013 scopus 로고
    • Selective inhibitory effects of the anticoagulant activated protein C on the responses of human mononuclear phagocytes to LPS, IFN-gamma, or phorbol ester
    • Grey ST, Tsuchida A, Hau H, Orthner CL, Salem HH, Hancock WW. Selective inhibitory effects of the anticoagulant activated protein C on the responses of human mononuclear phagocytes to LPS, IFN-gamma, or phorbol ester. J Immunol 1994;153:3664-72.
    • (1994) J Immunol , vol.153 , pp. 3664-3672
    • Grey, S.T.1    Tsuchida, A.2    Hau, H.3    Orthner, C.L.4    Salem, H.H.5    Hancock, W.W.6
  • 59
    • 8144228302 scopus 로고    scopus 로고
    • Gene expression profiling of inflamed human endothelial cells and influence of activated protein C
    • Franscini N, Bachli EB, Blau N, Leikauf MS, Schaffner A, Schoedon G. Gene expression profiling of inflamed human endothelial cells and influence of activated protein C. Circulation 2004;110:2903-9.
    • (2004) Circulation , vol.110 , pp. 2903-2909
    • Franscini, N.1    Bachli, E.B.2    Blau, N.3    Leikauf, M.S.4    Schaffner, A.5    Schoedon, G.6
  • 60
    • 0037036069 scopus 로고    scopus 로고
    • Activation of endothelial cell protease activated receptor 1 by the protein C pathway
    • Riewald M, Petrovan RJ, Donner A, Mueller BM, Ruf W. Activation of endothelial cell protease activated receptor 1 by the protein C pathway. Science 2002;296:1880-2.
    • (2002) Science , vol.296 , pp. 1880-1882
    • Riewald, M.1    Petrovan, R.J.2    Donner, A.3    Mueller, B.M.4    Ruf, W.5
  • 61
    • 17044427680 scopus 로고    scopus 로고
    • Endothelial barrier protection by activated protein C through PAR1-dependent sphingosine 1-phosphate receptor-1 crossactivation
    • Feistritzer C, Riewald AI. Endothelial barrier protection by activated protein C through PAR1-dependent sphingosine 1-phosphate receptor-1 crossactivation. Blood 2005;105:3178-84.
    • (2005) Blood , vol.105 , pp. 3178-3184
    • Feistritzer, C.1    Riewald, A.I.2
  • 62
    • 20444443508 scopus 로고    scopus 로고
    • Activated Protein C Mediates Novel Lung Endothelial Barrier Enhancement: Role of sphingosine 1-phosphat receptor transactivation
    • Finigan JH, Dudek SM, Singleton PA, Chiang ET, Jacobson JR, Camp SM, et al. Activated Protein C Mediates Novel Lung Endothelial Barrier Enhancement: Role of sphingosine 1-phosphat receptor transactivation. J Biol Chem 2005;280:17286-93.
    • (2005) J Biol Chem , vol.280 , pp. 17286-17293
    • Finigan, J.H.1    Dudek, S.M.2    Singleton, P.A.3    Chiang, E.T.4    Jacobson, J.R.5    Camp, S.M.6
  • 63
    • 17044433166 scopus 로고    scopus 로고
    • APC signaling: Tickling PAR1 for barrier protection?
    • Camerer E, Coughlin SR. APC signaling: tickling PAR1 for barrier protection? Blood 2005;105:3004-5.
    • (2005) Blood , vol.105 , pp. 3004-3005
    • Camerer, E.1    Coughlin, S.R.2
  • 65
    • 12444249948 scopus 로고    scopus 로고
    • Drotrecogin alfa (activated) (recombinant human activated protein C) reduces host coagulopathy response in patients with severe sepsis
    • Dhainaut JF, Yan SB, Margolis BD, Lorente JA, Russell JA, Freebairn RC, et al. Drotrecogin alfa (activated) (recombinant human activated protein C) reduces host coagulopathy response in patients with severe sepsis. Thromb Haemost 2003;90:642-53.
    • (2003) Thromb Haemost , vol.90 , pp. 642-653
    • Dhainaut, J.F.1    Yan, S.B.2    Margolis, B.D.3    Lorente, J.A.4    Russell, J.A.5    Freebairn, R.C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.