Efficient characterization of use-dependent ion channel blockers by real-time monitoring of channel state

Assay and Drug Development Technologies

Volumn 4, Issue 1, 2006, Pages 57-64

  Tao, Huimin ^a   Guia, António ^a   Xie, Betty ^a   SantaAna, David ^a   Manalo, Grace ^a   Xu, Jia ^a   Ghetti, Andrea ^a  

^a AVIVA Biosciences Corporation   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBAMAZEPINE; ION TRANSPORT AFFECTING AGENT; LAMOTRIGINE; LIDOCAINE; TETRACAINE; VOLTAGE GATED SODIUM CHANNEL;

ARTICLE; AUTOMATION; BINDING ASSAY; CHANNEL GATING; CONTROLLED STUDY; DRUG DESIGN; DRUG EFFICACY; DRUG RECEPTOR BINDING; DRUG RESEARCH; DRUG TARGETING; ELECTRODE; ELECTROPHYSIOLOGY; HUMAN; HUMAN CELL; MUSCLE CELL; NERVE CELL; VOLTAGE CLAMP;

CARBAMAZEPINE; CELL LINE; ELECTROPHYSIOLOGY; HUMANS; KINETICS; LIDOCAINE; MEMBRANE POTENTIALS; MEMBRANE TRANSPORT MODULATORS; MONITORING, PHYSIOLOGIC; MUSCLE PROTEINS; PATCH-CLAMP TECHNIQUES; REPRODUCIBILITY OF RESULTS; SODIUM CHANNELS; TETRACAINE; TRANSFECTION; TRIAZINES;

EID: 33645324423     PISSN: 1540658X     EISSN: None     Source Type: Journal    
DOI: 10.1089/adt.2006.4.57     Document Type: Article

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