Semisynthetic sphingoglycolipid LIGA20 is neuroprotective against human immunodeficiency virus-gp120-mediated apoptosis

Journal of Neuroscience Research

Volumn 83, Issue 5, 2006, Pages 890-896

  Bachis, Alessia ^a   Mocchetti, Italo ^a  

^a GEORGETOWN UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Apoptosis; Caspase 3; CXCR4; GM1; Neurotrophins; TrkB

Indexed keywords

BIOLOGICAL MARKER; BRAIN DERIVED NEUROTROPHIC FACTOR; CHEMOKINE RECEPTOR CXCR4; GLYCOPROTEIN GP 120; GLYCOPROTEIN GP 120 IIIB; GLYCOSPHINGOLIPID; K 252A; LIGAND; PROTEIN TYROSINE KINASE INHIBITOR; SPHINGOGLYCOLIPID LIGA20; STROMAL CELL DERIVED FACTOR 1; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BLOOD BRAIN BARRIER; BRAIN ATROPHY; CELL LOSS; CEREBELLUM; CONTROLLED STUDY; DRUG POTENCY; GRANULE CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; NERVE CELL NECROSIS; NERVE DEGENERATION; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; CELLS, CULTURED; CEREBELLUM; CHEMOKINES, CXC; G(M1) GANGLIOSIDE; HIV ENVELOPE PROTEIN GP120; IN SITU NICK-END LABELING; NEURONS; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, TRKB; SPHINGOSINE;

EID: 33645294624     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.20780     Document Type: Article

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