Effect of a polymorphonuclear elastase inhibitor (Sivelestat sodium) on acute lung injury after cardiopulmonary bypass: Findings of a double-blind randomized study

Surgery Today

Volumn 36, Issue 4, 2006, Pages 321-326

  Ryugo, Masahiro ^a   Sawa, Yoshiki ^a   Takano, Hiroshi ^a   Matsumiya, Goro ^a   Iwai, Shigemitsu ^a   Ono, Masamichi ^a   Hata, Hiroki ^a   Yamauchi, Takashi ^a   Nishimura, Masaji ^b   Fujino, Yuji ^a   Matsuda, Hikaru ^a  

^a OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b OSAKA UNIVERSITY HOSPITAL   (Japan)

Author keywords

Acute lung injury; Cardiopulmonary bypass; Polymorphonuclear elastase; Postperfusion syndrome; Sivelestat sodium; Systemic inflammatory response syndrome

Indexed keywords

ELASTASE INHIBITOR; INTERLEUKIN 8; SIVELESTAT; SODIUM CHLORIDE;

ADULT; ARTICLE; CARDIOPULMONARY BYPASS; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG MECHANISM; FEMALE; HUMAN; INTENSIVE CARE UNIT; LUNG INJURY; MALE; OXYGEN TENSION; PATIENT; RANDOMIZED CONTROLLED TRIAL; RESPIRATORY FUNCTION; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

ACUTE DISEASE; AGED; CARDIOPULMONARY BYPASS; FEMALE; GLYCINE; HUMANS; INTERLEUKIN-8; LEUKOCYTE ELASTASE; MALE; MIDDLE AGED; PERFUSION; RESPIRATORY DISTRESS SYNDROME, ADULT; SERINE PROTEINASE INHIBITORS; SULFONAMIDES; SYSTEMIC INFLAMMATORY RESPONSE SYNDROME;

EID: 33645289699     PISSN: 09411291     EISSN: 14362813     Source Type: Journal    
DOI: 10.1007/s00595-005-3160-y     Document Type: Article

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