Impact of early dietary gamma-linolenic acid supplementation on atopic eczema in infancy

Pediatric Allergy and Immunology

Volumn 17, Issue 2, 2006, Pages 112-117

  Kitz, Richard ^a   Rose, Markus A ^a   Schönborn, Heidrun ^a   Zielen, Stefan ^a   Böhles, Hans J ^a  

^a GOETHE UNIVERSITY   (Germany)

Author keywords

Atopic eczema; Gamma linolenic acid; Infancy; Nutrition; Prevention

Indexed keywords

FATTY ACID; GAMMA LINOLENIC ACID; IMMUNOGLOBULIN E; PLACEBO; POLYUNSATURATED FATTY ACID; PROTEIN HYDROLYSATE;

ARTICLE; ARTIFICIAL MILK; ATOPIC DERMATITIS; BREAST FEEDING; BREAST MILK; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIET SUPPLEMENTATION; DOUBLE BLIND PROCEDURE; FEEDING; FEMALE; HUMAN; INFANT; MAJOR CLINICAL STUDY; MOTHER; PARENT; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; WHEY;

BREAST FEEDING; DERMATITIS, ATOPIC; DIETARY FATS; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; FEMALE; GAMMA-LINOLENIC ACID; HUMANS; INFANT; INFANT FORMULA; INFANT, NEWBORN;

EID: 33645283091     PISSN: 09056157     EISSN: 13993038     Source Type: Journal    
DOI: 10.1111/j.1399-3038.2005.00369.x     Document Type: Article

References (27)

1. S u JC K emp AS V arigos GA N olan TM. Atopic eczema: its impact on the family and financial costs. Arch Dis Child 1997 76 159 62.
2. S aarinen UM B ackman A K ajossary M S ijmes MA. Prolonged breast feeding as prophylaxis for atopic disease. Lancet 1979 2 163 6.
3. K ramer MS. Does breast feeding help protect against atopic disease. J Pediatr 1988 112 181 90.
4. G ranot E G olan D B erry EM. Breast-fed and formula-fed infants do not differ in immunocompetent cell cytokine production despite differences in cell membrane fatty acid composition. Am J Clin Nutr 2000 72 1202 5.
5. W right S B olton C. Breast milk fatty acids in mothers of children with atopic eczema. Br J Nutr 1989 62 693 7.
6. B usinco L I oppi M M orse NL et al. Breast milk from mothers of children with newly developed atopic eczema has low levels of long chain polyunsaturated fatty acids. J Allergy Clin Immunol 1993 91 1134 9.
7. M elnik B P lewig G. Are disturbances of omega-6-fatty acid metabolism involved in the pathogenesis of atopic dermatitis Acta Derm Venereol Suppl 1992 176 77 85.
8. M anku MS H orrobin DF M orse N K yte V. Reduced levels of prostaglandin precursors in the blood of atopic patients: defective delta-6-desaturase function as a biochemical basis for atopy. Prostaglandins Leukot Med 1982 9 615 28.
9. M anku MS H orrobin DF M orse N et al. Essential fatty acids in the plasma phospholipids of patients with atopic eczema. Br J Dermatol 1984 110 643 8.
10. M elnik B P lewig G. Essential fatty acids, eicosanoids, and postnatal T-cell maturation implications for treatment and prevention of atopy. J Dermatolog Treat 1994 5 157 61.
11. M elnik BC P lewig G T schung T. Disturbances of essential fatty acid- and prostaglandin E-mediated immunoregulation in atopy. Prostaglandins Leukot Essent Fatty Acids 1991 42 125 30.
12. G alli E P icardo M C hini L P assi S. Analysis of polyunsaturated fatty acids in newborn sera: a screening tool for atopic disease Br J Dermatol 1994 130 752 6.
13. B eck M Z elczak G L entze MJ. Abnormal fatty acid composition in umbilical cord blood of infants at high risk of atopic disease. Acta Paediatr 2000 89 279 84.
14. K ankaanpää P N urmela K E rkkila A K alliomaki M. Polyunsaturated fatty acids in maternal diet, breast milk, and serum lipid fatty acids of infants in relation to atopy. Allergy 2001 56 633 8.
15. D uchen K Y u G B jörgsten B. Atopic sensitation during the first year of life in relation to long chain polyunsaturated fatty acid levels in human milk. Pediatr Res 1998 44 478 84.
16. van G ool CJAW T hijs C H enquet CJM et al. Gamma-linolenic acid supplementation for prophylaxis of atopic dermatitis-a randomized controlled trial in infants at high familial risk. Am J Clin Nutr 2003 77 943 51.
17. H anifen JM. Atopic dermatitis in infants and children. Pediatr Dermatol 1991 38 763 89.
18. B ergmann RL W ahn U B ergmann KE. The allergy march: from food to pollen. Environ Toxicol Pharmacol 1997 4 79 83.
19. L aske N N iggemann B. Does the severity of atopic dermatitis correlate with serum IgE levels Pediatr Allergy Immunol 2004 15 86 88.
20. P erkin MR S trachan DP W illiams HC et al. ALSPAC Study Team. Natural history of atopic dermatitis and its relationship to serum total immunoglobulin E in a population-based birth cohort study. Pediatr Allergy Immunol 2004 15 221 9.
21. B ergmann RL D iepgen TL K uss O et al. Breastfeeding duration is a risk factor for atopic eczema. Clin Exp Allergy 2002 32 205 9.
22. T hijs C H ouwelingen A P oorterman I et al. Essential fatty acids in breast milk of atopic mothers: comparison with non-atopic mothers, and effect of borage oil supplementation. Eur J Clin Nutr 2000 54 234 8.
23. L aubereau B B rockow I Z irngibl A et al. GINI Study Group: Effect of breast-feeding on the development of atopic dermatitis during the first 3 years of life -results from the GINI-birth cohort study. J Pediatr 2004 144 602 7.
24. S ears MR G reene JM W illiam AR et al. Long term relation between breast-feeding and development of atopy and asthma in children and young adults: a longitudinal study. Lancet 2002 360 901 7.
25. M iyake Y Y ura A I ki M. Breastfeeding and the prevalence of symptoms of allergic disorders in Japanese adolescents. Clin Exp Allergy 2003 33 312 6.
26. V an G ool CJ Z eegers MP T hijs C. Oral fatty acid supplementation in atopic dermatitis - a meta-analysis of placebo controlled trials. Br J Dermatol 2004 150 728 40.
27. W right S. Essential fatty acids and atopic dermatitis. Pediatr Allergy Immunol 1991 71 224 8.