메뉴 건너뛰기




Volumn 29, Issue 1, 2006, Pages 49-56

Amlodipine-induced reduction of oxidative stress in the brain is associated with sympatho-inhibitory effects in stroke-prone spontaneously hypertensive rats

Author keywords

Blood pressure; Heart rate; Hypertension; Oxidative stress; Sympathetic nervous system

Indexed keywords

AMLODIPINE; CALCIUM CHANNEL BLOCKING AGENT; DIHYDROPYRIDINE DERIVATIVE; DRINKING WATER; HYDRALAZINE; NICARDIPINE; NORADRENALIN; REACTIVE OXYGEN METABOLITE; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

EID: 33645279018     PISSN: 09169636     EISSN: 13484214     Source Type: Journal    
DOI: 10.1291/hypres.29.49     Document Type: Article
Times cited : (44)

References (62)
  • 1
    • 0344373794 scopus 로고    scopus 로고
    • Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic
    • The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group: The Antihypertensive, and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)
    • The ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group: Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic. The Antihypertensive, and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). JAMA 2002; 288: 2981-2997.
    • (2002) JAMA , vol.288 , pp. 2981-2997
  • 2
    • 2942635317 scopus 로고    scopus 로고
    • Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: The VALUE randomised trial
    • Julius S, Kjeldsen SE, Weber M, et al: Outcomes in hypertensive patients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial. Lancet 2004; 363: 2022-2031.
    • (2004) Lancet , vol.363 , pp. 2022-2031
    • Julius, S.1    Kjeldsen, S.E.2    Weber, M.3
  • 3
    • 0029132121 scopus 로고
    • Nifedipine: Dose-related increase in mortality in patients with coronary heart disease
    • Furberg CD, Psaty BM, Meyer JV: Nifedipine: dose-related increase in mortality in patients with coronary heart disease. Circulation 1995; 92: 1325-1331.
    • (1995) Circulation , vol.92 , pp. 1325-1331
    • Furberg, C.D.1    Psaty, B.M.2    Meyer, J.V.3
  • 4
    • 0034627164 scopus 로고    scopus 로고
    • Health outcomes associated with calcium antagonists compared with other first-line antihypertensive therapies: A meta-analysis of randomized controlled trials
    • Pahor M, Applegate WB, Williamson JD, et al: Health outcomes associated with calcium antagonists compared with other first-line antihypertensive therapies: a meta-analysis of randomized controlled trials. Lancet 2000; 356: 1949-1954.
    • (2000) Lancet , vol.356 , pp. 1949-1954
    • Pahor, M.1    Applegate, W.B.2    Williamson, J.D.3
  • 5
    • 0033830357 scopus 로고    scopus 로고
    • Current status of safety and efficacy of calcium channel blockers in cardiovascular diseases: A critical analysis based on 100 studies
    • Opie LH, Yasuf S, Küber W: Current status of safety and efficacy of calcium channel blockers in cardiovascular diseases: a critical analysis based on 100 studies. Prog Cardiovasc Dis 2000; 43: 171-196.
    • (2000) Prog Cardiovasc Dis , vol.43 , pp. 171-196
    • Opie, L.H.1    Yasuf, S.2    Küber, W.3
  • 6
    • 0030752323 scopus 로고    scopus 로고
    • Preservation of endogenous antioxidant activity and inhibition of lipid peroxidation as common mechanisms of antiatherosclerotic effects of vitamin E, lovastatin and amlodipine
    • Chen L, Haught WH, Yang B, Saldeen TG, Parathasarathy S, Mehta JL: Preservation of endogenous antioxidant activity and inhibition of lipid peroxidation as common mechanisms of antiatherosclerotic effects of vitamin E, lovastatin and amlodipine. J Am Coll Cardiol 1997; 30: 569-575.
    • (1997) J Am Coll Cardiol , vol.30 , pp. 569-575
    • Chen, L.1    Haught, W.H.2    Yang, B.3    Saldeen, T.G.4    Parathasarathy, S.5    Mehta, J.L.6
  • 7
    • 0942276494 scopus 로고    scopus 로고
    • Novel anti-inflammatory actions of amlodipine in a rat model of arteriosclerosis induced by long-term inhibition of nitric oxide synthesis
    • Kataoka C, Egashira K, Ishibashi M, et al: Novel anti-inflammatory actions of amlodipine in a rat model of arteriosclerosis induced by long-term inhibition of nitric oxide synthesis. Am J Physiol Heart Circ Physiol 2004; 286: H768-H774.
    • (2004) Am J Physiol Heart Circ Physiol , vol.286
    • Kataoka, C.1    Egashira, K.2    Ishibashi, M.3
  • 8
    • 0242552891 scopus 로고    scopus 로고
    • Trans-cellular proliferating cell nuclear antigen gene activation in cerebral vascular smooth muscle by endothelial oxidative injury in vivo
    • Gerzanich V, Ivanova S, van der Heijden MS, Zhou H, Simard JM: Trans-cellular proliferating cell nuclear antigen gene activation in cerebral vascular smooth muscle by endothelial oxidative injury in vivo. Arterioscler Thromb Vasc Biol 2003; 23: 2048-2054.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 2048-2054
    • Gerzanich, V.1    Ivanova, S.2    van der Heijden, M.S.3    Zhou, H.4    Simard, J.M.5
  • 9
  • 10
    • 0034718574 scopus 로고    scopus 로고
    • PREVENT Investigators: Effect of amlodipine on the progression of atherosclerosis and the occurrence of clinical events
    • Pitt B, Byington RP, Furberg CD, et al, PREVENT Investigators: Effect of amlodipine on the progression of atherosclerosis and the occurrence of clinical events. Circulation 2000; 102: 1503-1510.
    • (2000) Circulation , vol.102 , pp. 1503-1510
    • Pitt, B.1    Byington, R.P.2    Furberg, C.D.3
  • 11
    • 0031912146 scopus 로고    scopus 로고
    • Amlodipine releases nitric oxide from canine coronary microvessels: An unexpected mechanism of action of a calcium channel-blocking agent
    • Zhang X, Hintze TH: Amlodipine releases nitric oxide from canine coronary microvessels: an unexpected mechanism of action of a calcium channel-blocking agent. Circulation 1998; 97: 576-580.
    • (1998) Circulation , vol.97 , pp. 576-580
    • Zhang, X.1    Hintze, T.H.2
  • 12
    • 1642534463 scopus 로고    scopus 로고
    • Inhibition of oxidative stress and improvement of endothelial function by amlodipine in angiotensin II-infused rats
    • Zhou M-S, Jaimes EA, Raij L: Inhibition of oxidative stress and improvement of endothelial function by amlodipine in angiotensin II-infused rats. Am J Hypertens 2004; 17: 167-171.
    • (2004) Am J Hypertens , vol.17 , pp. 167-171
    • Zhou, M.-S.1    Jaimes, E.A.2    Raij, L.3
  • 14
    • 2342525162 scopus 로고    scopus 로고
    • Amlodipine and carvedilol prevent cytotoxicity in cortical neurons isolated from stroke-prone spontaneously hypertensive rats
    • Yamagata K, Ichinose S, Tagami M: Amlodipine and carvedilol prevent cytotoxicity in cortical neurons isolated from stroke-prone spontaneously hypertensive rats. Hypertens Res 2004; 27: 271-282.
    • (2004) Hypertens Res , vol.27 , pp. 271-282
    • Yamagata, K.1    Ichinose, S.2    Tagami, M.3
  • 15
    • 0036241008 scopus 로고    scopus 로고
    • Effects of chronic calcium channel blockade on sympathetic nerve activity in hypertension
    • Binggeli C, Corti R, Sudano I, Luscher TF, Noll G: Effects of chronic calcium channel blockade on sympathetic nerve activity in hypertension. Hypertension 2002; 39: 892-896.
    • (2002) Hypertension , vol.39 , pp. 892-896
    • Binggeli, C.1    Corti, R.2    Sudano, I.3    Luscher, T.F.4    Noll, G.5
  • 16
    • 0033669301 scopus 로고    scopus 로고
    • Effects of different dihydropyridine calcium antagonists on plasma norepinephrine in essential hypertension
    • Fogari R, Zoppi A, Corradi L, Preti P, Malalamani GD, Mugellini A: Effects of different dihydropyridine calcium antagonists on plasma norepinephrine in essential hypertension. J Hypertens 2000; 18: 1871-1875.
    • (2000) J Hypertens , vol.18 , pp. 1871-1875
    • Fogari, R.1    Zoppi, A.2    Corradi, L.3    Preti, P.4    Malalamani, G.D.5    Mugellini, A.6
  • 17
    • 0031941183 scopus 로고    scopus 로고
    • Evaluation of changes in sympathetic nerve activity and heart rate in essential hypertensive patients induced by amlodipine and nifedipine
    • Hamada T, Watanabe M, Kaneda T, et al: Evaluation of changes in sympathetic nerve activity and heart rate in essential hypertensive patients induced by amlodipine and nifedipine. J Hypertens 1998; 16: 111-118.
    • (1998) J Hypertens , vol.16 , pp. 111-118
    • Hamada, T.1    Watanabe, M.2    Kaneda, T.3
  • 18
    • 21244499765 scopus 로고    scopus 로고
    • Protective effects of an angiotensin II receptor blocker and a long-acting calcium channel blocker against cardiovascular organ injuries in hypertensive patients
    • Ishimitsu T, Kobayashi T, Honda T, et al: Protective effects of an angiotensin II receptor blocker and a long-acting calcium channel blocker against cardiovascular organ injuries in hypertensive patients. Hypertens Res 2005; 28: 351-359.
    • (2005) Hypertens Res , vol.28 , pp. 351-359
    • Ishimitsu, T.1    Kobayashi, T.2    Honda, T.3
  • 19
    • 0027299748 scopus 로고
    • Structure and functional expression of a member of the low voltage-activated calcium channel family
    • Soong TW, Stea A, Hodson CD, Dubel SJ, Vincent SR, Snutch TP: Structure and functional expression of a member of the low voltage-activated calcium channel family. Science 1993; 260: 1133-1136.
    • (1993) Science , vol.260 , pp. 1133-1136
    • Soong, T.W.1    Stea, A.2    Hodson, C.D.3    Dubel, S.J.4    Vincent, S.R.5    Snutch, T.P.6
  • 20
    • 0023104271 scopus 로고
    • Multiple calcium channels and neuronal function
    • Miller RJ: Multiple calcium channels and neuronal function. Science 1987; 235: 46-52.
    • (1987) Science , vol.235 , pp. 46-52
    • Miller, R.J.1
  • 21
    • 0033954871 scopus 로고    scopus 로고
    • Sympatho-inhibition by central and peripheral infusion of nifedipine in spontaneously hypertensive rats
    • Murzenok PP, Huang BS, Leenen FHH: Sympatho-inhibition by central and peripheral infusion of nifedipine in spontaneously hypertensive rats. Hypertension 2000; 35: 631-636.
    • (2000) Hypertension , vol.35 , pp. 631-636
    • Murzenok, P.P.1    Huang, B.S.2    Leenen, F.H.H.3
  • 22
    • 0042303833 scopus 로고    scopus 로고
    • Sympathoinhibitory and depressor effects of amlodipine in spontaneously hypertensive rats
    • Huang BS, Leenen FHH: Sympathoinhibitory and depressor effects of amlodipine in spontaneously hypertensive rats. J Cardiovasc Pharmacol 2003; 42: 153-160.
    • (2003) J Cardiovasc Pharmacol , vol.42 , pp. 153-160
    • Huang, B.S.1    Leenen, F.H.H.2
  • 23
    • 2442706556 scopus 로고    scopus 로고
    • Increased reactive oxygen species in rostral ventrolateral medulla contribute to neural mechanisms of hypertension in stroke-prone spontaneously hypertensive rats
    • Kishi T, Hirooka. Y, Kimura Y, Ito K, Shimokawa H, Takeshita A: Increased reactive oxygen species in rostral ventrolateral medulla contribute to neural mechanisms of hypertension in stroke-prone spontaneously hypertensive rats. Circulation 2004; 109: 2357-2362.
    • (2004) Circulation , vol.109 , pp. 2357-2362
    • Kishi, T.1    Hirooka, Y.2    Kimura, Y.3    Ito, K.4    Shimokawa, H.5    Takeshita, A.6
  • 24
    • 4444329422 scopus 로고    scopus 로고
    • Reactive oxygen species, vascular oxidative stress, and redox signaling in hypertension
    • Touyz RM: Reactive oxygen species, vascular oxidative stress, and redox signaling in hypertension. Hypertension 2004; 44: 248-252.
    • (2004) Hypertension , vol.44 , pp. 248-252
    • Touyz, R.M.1
  • 26
    • 0032209587 scopus 로고    scopus 로고
    • Different effects of nifedipine and amlodipine on circulating catecholamine levels in essential hypertensive patients
    • De Champlain J, Karas M, Nguyen P, et al: Different effects of nifedipine and amlodipine on circulating catecholamine levels in essential hypertensive patients. J Hypertens 1998; 16: 1357-1369.
    • (1998) J Hypertens , vol.16 , pp. 1357-1369
    • De Champlain, J.1    Karas, M.2    Nguyen, P.3
  • 27
    • 0037388639 scopus 로고    scopus 로고
    • Calcium antagonist treatment by lercanidipine prevents hyperpolarization in essential hypertension
    • Taddei S, Virdis A, Ghiadoni L, et al: Calcium antagonist treatment by lercanidipine prevents hyperpolarization in essential hypertension. Hypertension 2003; 41: 950-955.
    • (2003) Hypertension , vol.41 , pp. 950-955
    • Taddei, S.1    Virdis, A.2    Ghiadoni, L.3
  • 28
    • 0842346444 scopus 로고    scopus 로고
    • Angiotensin converting enzyme inhibition and calcium channel blockage improves cyclosporine induced glucose intolerance in rats
    • Yavuz DG, Tugler S, Koçak H, Ozener C, Akoglu E, Akalin S: Angiotensin converting enzyme inhibition and calcium channel blockage improves cyclosporine induced glucose intolerance in rats. Transplant Proc 2004; 36: 171-174.
    • (2004) Transplant Proc , vol.36 , pp. 171-174
    • Yavuz, D.G.1    Tugler, S.2    Koçak, H.3    Ozener, C.4    Akoglu, E.5    Akalin, S.6
  • 29
    • 13244252617 scopus 로고    scopus 로고
    • Different effect of losartan and amlodipine on penile structure in male spontaneously hypertensive rats
    • Toblli JE, Stella I, Mazza ON, Fender L, Inserra F: Different effect of losartan and amlodipine on penile structure in male spontaneously hypertensive rats. Am J Nephrol 2004; 24: 614-623.
    • (2004) Am J Nephrol , vol.24 , pp. 614-623
    • Toblli, J.E.1    Stella, I.2    Mazza, O.N.3    Fender, L.4    Inserra, F.5
  • 30
    • 27744458898 scopus 로고    scopus 로고
    • G-nitro-L-arginine methyl ester-induced hypertensive rat aorta: Vasoprotective effects beyond the blood pressure lowering effects of amlodipine and manidipine
    • G-nitro-L-arginine methyl ester-induced hypertensive rat aorta: vasoprotective effects beyond the blood pressure lowering effects of amlodipine and manidipine. Hypertens Res 2005; 28: 689-700.
    • (2005) Hypertens Res , vol.28 , pp. 689-700
    • Toba, H.1    Nakagawa, Y.2    Miki, S.3
  • 31
    • 0037332063 scopus 로고    scopus 로고
    • Atorvastatin causes depressor and sympatho-inhibitory effects with upregulation of nitric oxide synthases in stroke-prone spontaneously hypertensive rats
    • Kishi T, Hirooka Y, Mukai Y, Shimokawa H, Takeshita A: Atorvastatin causes depressor and sympatho-inhibitory effects with upregulation of nitric oxide synthases in stroke-prone spontaneously hypertensive rats. J Hypertens 2003; 21: 379-386.
    • (2003) J Hypertens , vol.21 , pp. 379-386
    • Kishi, T.1    Hirooka, Y.2    Mukai, Y.3    Shimokawa, H.4    Takeshita, A.5
  • 32
    • 0033588198 scopus 로고    scopus 로고
    • Mitochondrial electron transport complex I is a potential source of oxygen free radicals in the failing myocardium
    • Ide T, Tsutsui H, Kinugawa S, et al: Mitochondrial electron transport complex I is a potential source of oxygen free radicals in the failing myocardium. Circ Res 1999; 85: 357-363.
    • (1999) Circ Res , vol.85 , pp. 357-363
    • Ide, T.1    Tsutsui, H.2    Kinugawa, S.3
  • 33
    • 17544379019 scopus 로고    scopus 로고
    • Direct evidence for increased hydroxyradicals originating from superoxide in the failing myocardium
    • Ide T, Tsutsui H, Kinugawa S, et al: Direct evidence for increased hydroxyradicals originating from superoxide in the failing myocardium. Circ Res 2000; 86: 152-157.
    • (2000) Circ Res , vol.86 , pp. 152-157
    • Ide, T.1    Tsutsui, H.2    Kinugawa, S.3
  • 34
    • 0842332607 scopus 로고    scopus 로고
    • Rho/Rho-kinase pathway in the brainstem contributes to hypertension caused by chronic nitric oxide synthase inhibition
    • Ito K, Hirooka Y, Kishi T, et al: Rho/Rho-kinase pathway in the brainstem contributes to hypertension caused by chronic nitric oxide synthase inhibition. Hypertension 2004; 43: 156-162.
    • (2004) Hypertension , vol.43 , pp. 156-162
    • Ito, K.1    Hirooka, Y.2    Kishi, T.3
  • 35
    • 13444279868 scopus 로고    scopus 로고
    • Overexpression of inducible nitric oxide synthase in rostral ventrolateral medulla causes hypertension and sympathoexcitation via an increase in oxidative stress
    • Kimura Y, Hirooka Y, Sagara Y, et al: Overexpression of inducible nitric oxide synthase in rostral ventrolateral medulla causes hypertension and sympathoexcitation via an increase in oxidative stress. Circ Res 2005; 96: 252-260.
    • (2005) Circ Res , vol.96 , pp. 252-260
    • Kimura, Y.1    Hirooka, Y.2    Sagara, Y.3
  • 36
    • 0030454437 scopus 로고    scopus 로고
    • Antioxidant effects of calcium antagonists on rat myocardial membrane lipid peroxidation
    • Sugawara H, Tobise K, Kikuchi K: Antioxidant effects of calcium antagonists on rat myocardial membrane lipid peroxidation. Hypertens Res 1996; 19: 223-228.
    • (1996) Hypertens Res , vol.19 , pp. 223-228
    • Sugawara, H.1    Tobise, K.2    Kikuchi, K.3
  • 37
    • 0034624286 scopus 로고    scopus 로고
    • Structural alterations of tight junctions are associated with loss of polarity in stroke-prone spontaneously hypertensive rat blood-brain barrier endothelial cells
    • Lippoldt A, Kneisel U, Liebner S, et al: Structural alterations of tight junctions are associated with loss of polarity in stroke-prone spontaneously hypertensive rat blood-brain barrier endothelial cells. Brain Res 2000; 885: 251-261.
    • (2000) Brain Res , vol.885 , pp. 251-261
    • Lippoldt, A.1    Kneisel, U.2    Liebner, S.3
  • 38
    • 0037025379 scopus 로고    scopus 로고
    • 2+ channels in neurons by increasing protein tyrosine phosphorylation
    • 2+ channels in neurons by increasing protein tyrosine phosphorylation. J Biol Chem 2002; 277: 24368-24375.
    • (2002) J Biol Chem , vol.277 , pp. 24368-24375
    • Lu, C.1    Chan, S.L.2    Mattson, M.P.3
  • 39
    • 0037212650 scopus 로고    scopus 로고
    • Neuronal death signaling by β-bungarotoxin through the activation of the N-methyl-D-aspartate (NMDA) receptor and L-type calcium channel
    • Tseng W-P, Lin-Shiau S-Y: Neuronal death signaling by β-bungarotoxin through the activation of the N-methyl-D-aspartate (NMDA) receptor and L-type calcium channel. Biochem Pharmacol 2003; 65: 131-142.
    • (2003) Biochem Pharmacol , vol.65 , pp. 131-142
    • Tseng, W.-P.1    Lin-Shiau, S.-Y.2
  • 40
    • 0442307866 scopus 로고    scopus 로고
    • Activation of ERK5 is mediated by N-methyl-D-aspartate receptor and L-type voltage-gated calcium channel via Src involving oxidative stress after cerebral ischemia in rat hippocampus
    • Wang R-M, Zhang Q-G, Zhang G-Y: Activation of ERK5 is mediated by N-methyl-D-aspartate receptor and L-type voltage-gated calcium channel via Src involving oxidative stress after cerebral ischemia in rat hippocampus. Neurosci Lett 2004; 357: 13-16.
    • (2004) Neurosci Lett , vol.357 , pp. 13-16
    • Wang, R.-M.1    Zhang, Q.-G.2    Zhang, G.-Y.3
  • 41
    • 0037118682 scopus 로고    scopus 로고
    • Nifedipine indirectly upregulates superoxide dismutase expression in endothelial cells via vascular smooth muscle cell-dependent pathways
    • Fukuo K, Yang J, Yasuda OO et al: Nifedipine indirectly upregulates superoxide dismutase expression in endothelial cells via vascular smooth muscle cell-dependent pathways. Circulation 2002; 106: 356-361.
    • (2002) Circulation , vol.106 , pp. 356-361
    • Fukuo, K.1    Yang, J.2    Yasuda, O.O.3
  • 42
    • 0032824467 scopus 로고    scopus 로고
    • 1,4-Dihydropyridine calcium channel blockers inhibit plasma and LDL oxidation and formation of oxidation-specific epitopes in the arterial wall and prolong survival in stroke-prone spontaneously hypertensive rats
    • Napoli C, Salomone S, Godfraind T, et al: 1,4-Dihydropyridine calcium channel blockers inhibit plasma and LDL oxidation and formation of oxidation-specific epitopes in the arterial wall and prolong survival in stroke-prone spontaneously hypertensive rats. Stroke 1999; 30: 1907-1915.
    • (1999) Stroke , vol.30 , pp. 1907-1915
    • Napoli, C.1    Salomone, S.2    Godfraind, T.3
  • 43
    • 0037383133 scopus 로고    scopus 로고
    • Increased platelet-activating factor-induced periventricular brain microvascular constriction associated with immaturity
    • Hou X, Gobeil F, Marrache AM, et al: Increased platelet-activating factor-induced periventricular brain microvascular constriction associated with immaturity. Am J Physiol Regul Integr Comp Physiol 2003; 284: 928-935.
    • (2003) Am J Physiol Regul Integr Comp Physiol , vol.284 , pp. 928-935
    • Hou, X.1    Gobeil, F.2    Marrache, A.M.3
  • 44
    • 0026681664 scopus 로고
    • Interpretation of the thiobarbituric acid reactivity of rat liver and brain homogenates in the presence of ferric ion and ethylenediaminetetraacetic acid
    • Kikugawa K, Kojima T, Yamaki S, Kosugi H: Interpretation of the thiobarbituric acid reactivity of rat liver and brain homogenates in the presence of ferric ion and ethylenediaminetetraacetic acid. Anal Biochem 1992; 202: 249-255.
    • (1992) Anal Biochem , vol.202 , pp. 249-255
    • Kikugawa, K.1    Kojima, T.2    Yamaki, S.3    Kosugi, H.4
  • 45
    • 0028939907 scopus 로고
    • Mitochondrial lipid peroxidation and superoxide dismutase in rat hypertensive target organs
    • Ohtsuki T, Matsumoto M, Suzuki K, Taniguchi N, Kamada T: Mitochondrial lipid peroxidation and superoxide dismutase in rat hypertensive target organs. Am J Physiol 1995; 268: H1418-H1421.
    • (1995) Am J Physiol , vol.268
    • Ohtsuki, T.1    Matsumoto, M.2    Suzuki, K.3    Taniguchi, N.4    Kamada, T.5
  • 46
    • 0036182873 scopus 로고    scopus 로고
    • Cardiovascular effects of overexpression of endothelial nitric oxide synthase in the rostral ventrolateral medulla in stroke-prone spontaneously hypertensive rats
    • Kishi T, Hirooka Y, Ito K, Sakai K, Shimokawa H, Takeshita A: Cardiovascular effects of overexpression of endothelial nitric oxide synthase in the rostral ventrolateral medulla in stroke-prone spontaneously hypertensive rats. Hypertension 2002; 39: 264-268.
    • (2002) Hypertension , vol.39 , pp. 264-268
    • Kishi, T.1    Hirooka, Y.2    Ito, K.3    Sakai, K.4    Shimokawa, H.5    Takeshita, A.6
  • 47
    • 0028258843 scopus 로고
    • Functional organization of central pathways regulating the cardiovascular system
    • Dampney RAL: Functional organization of central pathways regulating the cardiovascular system. Physiol Rev 1994; 74: 323-364.
    • (1994) Physiol Rev , vol.74 , pp. 323-364
    • Dampney, R.A.L.1
  • 48
    • 0036734231 scopus 로고    scopus 로고
    • Baroreceptor reflex pathways and neurotransmitters: 10 years on
    • Pilowsky PM, Goodchild AK: Baroreceptor reflex pathways and neurotransmitters: 10 years on. J Hypertens 2002; 20: 1675-1688.
    • (2002) J Hypertens , vol.20 , pp. 1675-1688
    • Pilowsky, P.M.1    Goodchild, A.K.2
  • 49
    • 0021850381 scopus 로고
    • Arterial pressure and heart rate responses to calcium channel blockers administered in the brainstem in rats
    • Higuchi S, Takeshita A, Ito N, Imaizumi T, Matsuguchi H, Nakamura M: Arterial pressure and heart rate responses to calcium channel blockers administered in the brainstem in rats. Circ Res 1985; 57: 244-251.
    • (1985) Circ Res , vol.57 , pp. 244-251
    • Higuchi, S.1    Takeshita, A.2    Ito, N.3    Imaizumi, T.4    Matsuguchi, H.5    Nakamura, M.6
  • 50
    • 0037189120 scopus 로고    scopus 로고
    • Mechanisms of action of nitric oxide in the brain stem
    • Zanzinger J: Mechanisms of action of nitric oxide in the brain stem. Auton Neurosci 2002; 98: 24-27.
    • (2002) Auton Neurosci , vol.98 , pp. 24-27
    • Zanzinger, J.1
  • 51
    • 0035683747 scopus 로고    scopus 로고
    • Role of nitric oxide in central sympathetic outflow
    • Patel KP, Li Y-F, Hirooka Y: Role of nitric oxide in central sympathetic outflow. Exp Biol Med 2001; 226: 814-824.
    • (2001) Exp Biol Med , vol.226 , pp. 814-824
    • Patel, K.P.1    Li, Y.-F.2    Hirooka, Y.3
  • 52
    • 0037986819 scopus 로고    scopus 로고
    • Enhanced depressor response to endothelial nitric oxide synthase gene transfer into the nucleus tractus solitarii of spontaneously hypertensive rats
    • Hirooka Y, Sakai K, Kishi T, Ito K, Shimokawa H, Takeshita A: Enhanced depressor response to endothelial nitric oxide synthase gene transfer into the nucleus tractus solitarii of spontaneously hypertensive rats. Hypertens Res 2003; 26: 325-331.
    • (2003) Hypertens Res , vol.26 , pp. 325-331
    • Hirooka, Y.1    Sakai, K.2    Kishi, T.3    Ito, K.4    Shimokawa, H.5    Takeshita, A.6
  • 54
    • 14644433145 scopus 로고    scopus 로고
    • Calcium antagonist reduces oxidative stress by upregulating Cu/Zn superoxide dismutase in stroke-prone spontaneously hypertensive rats
    • Umemoto S, Tanaka M, Kawahara S, et al: Calcium antagonist reduces oxidative stress by upregulating Cu/Zn superoxide dismutase in stroke-prone spontaneously hypertensive rats. Hypertens Res 2004; 27: 877-885.
    • (2004) Hypertens Res , vol.27 , pp. 877-885
    • Umemoto, S.1    Tanaka, M.2    Kawahara, S.3
  • 56
    • 0032832660 scopus 로고    scopus 로고
    • Age-related change of anti-oxidant capacities in the cerebral cortex and hippocampus of stroke-prone spontaneously hypertensive rats
    • Kimoto-Kinoshita S, Nishida S, Tomura TT: Age-related change of anti-oxidant capacities in the cerebral cortex and hippocampus of stroke-prone spontaneously hypertensive rats. Neurosci Lett 1999; 273: 41-44.
    • (1999) Neurosci Lett , vol.273 , pp. 41-44
    • Kimoto-Kinoshita, S.1    Nishida, S.2    Tomura, T.T.3
  • 57
    • 0025395048 scopus 로고
    • Role of oxygen-derived free radicals in acute angiotensin II-induced hypertensive vascular disease in the rat
    • Wilson SK: Role of oxygen-derived free radicals in acute angiotensin II-induced hypertensive vascular disease in the rat. Circ Res 1990; 66: 722-734.
    • (1990) Circ Res , vol.66 , pp. 722-734
    • Wilson, S.K.1
  • 58
    • 0025180708 scopus 로고
    • Superoxide dismutase reduces permeability and edema induced by hypertension in rats
    • Zhang XM, Ellis EF: Superoxide dismutase reduces permeability and edema induced by hypertension in rats. Am J Physiol 1990; 259: H497-H503.
    • (1990) Am J Physiol , vol.259
    • Zhang, X.M.1    Ellis, E.F.2
  • 59
    • 0028801341 scopus 로고
    • Role of superoxide in the depressed nitric oxide production by the endothelium of genetically hypertensive rats
    • Grunfeld S, Hamilton CA, Mesaros S, et al: Role of superoxide in the depressed nitric oxide production by the endothelium of genetically hypertensive rats. Hypertension 1995; 26: 854-857.
    • (1995) Hypertension , vol.26 , pp. 854-857
    • Grunfeld, S.1    Hamilton, C.A.2    Mesaros, S.3
  • 60
    • 3042621503 scopus 로고    scopus 로고
    • Preventing dementia by treating hypertension and preventing stroke
    • Spence JD: Preventing dementia by treating hypertension and preventing stroke. Hypertension 2004; 44: 20-21.
    • (2004) Hypertension , vol.44 , pp. 20-21
    • Spence, J.D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.