CJZ3, a lomerizine derivative, modulates P-glycoprotein function in rat brain microvessel endothelial cells

Acta Pharmacologica Sinica

Volumn 27, Issue 4, 2006, Pages 414-418

  Ji, Bian Sheng ^a   He, Ling ^b   Li, Xiao Qu ^c   Liu, Guo Qing ^b  

^a HENAN UNIVERSITY   (China)

^b CHINA PHARMACEUTICAL UNIVERSITY   (China)

^c BEIJING NORMAL UNIVERSITY   (China)

Author keywords

Blood brain barrier; CJZ3; P glycoprotein

Indexed keywords

CJZ 3; DRUG DERIVATIVE; GLYCOPROTEIN P; LOMERIZINE; RHODAMINE 123; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN MICROCIRCULATION; CONCENTRATION RESPONSE; CULTURE MEDIUM; DRUG ACCUMULATION; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; DRUG STRUCTURE; DRUG TRANSPORT; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; HUMAN UMBILICAL VEIN ENDOTHELIUM CELL; MICROVASCULATURE; MODULATION; NONHUMAN; PROTEIN FUNCTION; RAT; SPECTROFLUOROMETRY; UMBILICAL VEIN; VASCULAR ENDOTHELIUM;

ANIMALS; BRAIN; CALCIUM CHANNEL BLOCKERS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; HUMANS; MICROCIRCULATION; MOLECULAR STRUCTURE; P-GLYCOPROTEIN; PIPERAZINES; RATS; RATS, SPRAGUE-DAWLEY; RHODAMINE 123;

EID: 33645224988     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1111/j.1745-7254.2006.00294.x     Document Type: Article

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