In vitro bioactivity of combustion products from 12 tobacco constituents

Food and Chemical Toxicology

Volumn 44, Issue 5, 2006, Pages 724-738

  Préfontaine, David ^a,b   Morin, André ^a   Jumarie, Catherine ^b   Porter, Andrew ^c  

^a Imperial Tobacco Canada Ltd   (Canada)

^b UNIVERSITÉ DU QUÉBEC À MONTRÉAL   (Canada)

^c BRITISH AMERICAN TOBACCO   (United Kingdom)

Author keywords

Combustion; In vitro toxicity; Micronucleus assay; Neutral red uptake; Salmonella mutagenicity; Tobacco constituents

Indexed keywords

AMINO ACID DERIVATIVE; CARBOHYDRATE DERIVATIVE; CARBOXYLIC ACID DERIVATIVE; CELLULOSE; CHLOROGENIC ACID; GLUCOSE; GLYCINE; LIGNIN; MALIC ACID; NITROGEN DERIVATIVE; PECTIN; PHENOL DERIVATIVE; POLYPHENOL DERIVATIVE; PROLINE; PROTEIN DERIVATIVE; RIBULOSEBISPHOSPHATE CARBOXYLASE; SOLVENT; STARCH; TOBACCO SMOKE; TRYPTOPHAN; TYROSINE;

ANIMAL CELL; ARTICLE; CELL PROLIFERATION; CHROMOSOME DAMAGE; COMBUSTION; CONTROLLED STUDY; CYTOTOXICITY; CYTOTOXICITY TEST; DRY WEIGHT; GENOTOXICITY; IN VITRO STUDY; LIVER; MAMMAL CELL; METABOLIC ACTIVATION; MICRONUCLEUS TEST; MICROSOME; MUTAGEN TESTING; MUTAGENIC ACTIVITY; NONHUMAN; PARTICULATE MATTER; PLANT LEAF; PRECURSOR; RAT; SALMONELLA; TOBACCO;

ANALYSIS OF VARIANCE; ANIMALS; BIOLOGICAL ASSAY; CELLS, CULTURED; CRICETINAE; DOSE-RESPONSE RELATIONSHIP, DRUG; MICRONUCLEUS TESTS; MUTAGENICITY TESTS; PLANT LEAVES; SMOKE; TOBACCO; TOBACCO INDUSTRY;

ANIMALIA; CRICETINAE; MAMMALIA; NICOTIANA TABACUM; SALMONELLA; SALMONELLA TYPHIMURIUM;

EID: 33645224277     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.fct.2005.10.005     Document Type: Article

References (52)

1. C. Andreoli, D. Gigante, and A. Nunziata A review of in vitro methods to assess the biological activity of tobacco smoke with the aim of reducing the toxicity of smoke Toxicol. In Vitro 17 2003 587 594
2. R.R. Baker, E.D. Massey, and G. Smith An overview of the effects of tobacco ingredients on smoke chemistry and toxicity Food Chem. Toxicol. 42S 2004 S53 S83
3. Baker, R.R., Proctor, C., 2001. Where there's smoke. In: Chemistry in Britain, London, Chemical Education Trust Fund for the Chemical Society and the Royal Institute of Chemistry Royal Society of Chemistry, January, pp. 38-41.
4. B.R. Bombick, H. Murli, J.T. Avalos, D. Bombick, W.T. Morgan, K.P. Putnam, and D.J. Doolittle Chemical and biological studies of a new cigarette that primarily heats tobacco. Part 2. In vitro toxicity of mainstream smoke condensate Food Chem. Toxicol. 36 1998 183 190
5. E. Borenfreund, and J. Puerner Toxicity determination in vitro by morphological alterations and neutral red absorption Toxicol. Lett. 24 1985 119 124
6. R. Ciranni, R. Barale, G. Ghelardini, and N. Loprieno Benzene and the genotoxicity of its metabolites. II. The effect of the route of administration on the micronuclei and bone marrow depression in mouse bone marrow cells Mutat. Res. 209 1988 23 28
7. W.L. Clapp, B.S. Fagg, and C.J. Smith Reduction in Ames Salmonella mutagenicity of cigarette mainstream smoke condensate by tobacco protein removal Mutat. Res. 446 1999 167 174
8. D.M. DeMarini Genotoxicity of tobacco smoke and tobacco smoke condensate: a review Mutat. Res. 567 2004 447 474
9. D.J. Doolittle, C.K. Lee, J.L. Ivett, J.C. Mirsalis, E. Riccio, C.J. Rudd, G.T. Burger, and A.W. Hayes Genetic toxicology studies comparing the activity of sidestream smoke from cigarettes which burn or only heat tobacco Mutat. Res. 240 1990 59 72
10. M.F. Dube, and C.R. Green Methods of collection of smoke for analytical purposes Rec. Adv. Tob. Sci. 8 1982 42 102
11. M. Fenech, W.P. Chang, M. Kirsch-Volders, N. Holland, S. Bonassi, and E. Zeiger HUMN project: detailed description of the scoring criteria for the cytokinesis-block micronucleus assay using isolated human lymphocyte cultures Mutat. Res. 534 2003 65 75
12. C.R. Green, and A. Rodgman The tobacco chemists research conference: a half century forum for advances in analytical methodology of tobacco and its products Rec. Adv. Tob. Sci. 22 1996 131 304
13. D. Hanahan, and R.A. Weinberg The hallmarks of cancer Cell 100 2000 57 70
14. S.S. Hecht Tobacco smoke carcinogens and lung cancer J. Natl. Cancer Inst. 91 1999 1194 1210
15. G.L. Huber Physical, chemical, and biological properties of tobacco, cigarette smoke, and other tobacco products Semin. Respir. Med. 10 1989 297 332
16. International Organization for Standardization: International standard ISO 10362-1, 1999. Determination of Water in Smoke Condensates. Part 1: Gas-Chromatographic Method, 2nd ed.
17. International Organization for Standardization: International standard ISO 10315, 2000. Cigarettes. Determination of Nicotine in Smoke Condensates. Gas-Chromatographic Method, 2nd ed.
18. M. Kirsch-Volders, T. Sofuni, M. Aardema, S. Albertini, D. Eastmond, M. Fenech, M. Ishidate Jr., S. Kirchner, E. Lorge, T. Morita, H. Norppa, J. Surrallès, A. Vanhauwaert, and A. Wakata Report from the in vitro micronucleus assay working group Mutat. Res. 540 2003 153 163
19. J.C. Leffingwell Basic chemical constituents of tobacco leaf and differences among tobacco types D.L. Davis M.T. Nielsen Tobacco. Production, Chemistry and Technology 1999 Blackwell Science Oxford 265 284
20. D.M. Maron, and B.N. Ames Revised methods for the Salmonella mutagenicity test Mutat. Res. 113 1983 173 215
21. N. Matsukura, J. Willey, M. Miyashita, B. Taffe, D. Hoffmann, C. Waldren, T.T. Puck, and C.C. Harris Detection of direct mutagenicity of cigarette smoke condensate in mammalian cells Carcinogenesis 12 1991 685 689
22. T. Matsumoto, D. Yoshida, S. Mizusaki, and H. Okamoto Mutagenic activity of amino acid pyrolysates in Salmonella typhimurium TA98 Mutat. Res. 48 1977 279 286
23. M. Mumtaz, M. Sipes, H.J. Clewell, and R.S. Yang Risk assessment of chemical mixtures: biologic and toxicologic issues Fundam. Appl. Toxicol. 21 1993 258 269
24. M. Nagao, M. Honda, Y. Seino, T. Yahagi, N. Matsukura, T. Sugimura, K. Wakabayashi, K. Tsuji, and T. Kosuge Mutagens in foods, and especially pyrolysis products of proteins D. Scott B.A. Dridges F.H. Sobels Progress in Genetic Toxicology 1977 Elsevier/North-Holland Amsterdam 259 264
25. NIH-National Institutes of Health (2001). Guidance document on using in vitro data to estimate in vivo starting doses for acute toxicity. Report of the Interagency Coordinating Committee on the Validation of Alternative Methods (ICCVAM) and the National Toxicology Program. Department of Health and Human Services, US Public Health Service, National Institutes of Health, Research Triangle Park, NC, NIH Publication No. 01-4500.
26. OECD-Organisation for Economic Co-operation and Development, 1997. Environmental Directorate. Guideline for Testing of Chemicals. Guideline 471: Bacterial Reverse Mutation Test.
27. OECD-Organisation for Economic Co-operation and Development, 2004. Environmental Directorate. Guideline for Testing of Chemicals. Draft Proposal for a New Guideline 487: In Vitro Micronucleus Test.
28. Peeler, C.L., 1996. Smoking and Tobacco Control, Monograph 7. The FTC cigarette test method for determining tar, nicotine, and carbon monoxide yields of US cigarettes: report of the NCI expert committee. Cigarette testing and the Federal Trade Commission: a historical overview. Department of Health and Human Services, US Public Health Service, National Institutes of Health, Bethesda, MD, NIH Publication No. 96-4028.
29. C. Perez, A. Lopez de Cerain, and J. Bello Induction of micronuclei in V79 cells after combined treatments with heterocyclic aromatic amines Food Chem. Toxicol. 40 2002 1463 1467
30. T.A. Perfetti, W.M. Coleman, and W.S. Smith Determination of mainstream and sidestream cigarette smoke components for cigarettes of different tobacco types and a set of reference cigarettes Beitr. Tabakforsch. Int. 18 1998 95 113
31. W. Pfau, F.L. Martin, K.J. Cole, S. Venitt, D.H. Phillips, P.L. Grover, and H. Marquardt Heterocyclic aromatic amines induce DNA strand breaks and cell transformation Carcinogenesis 20 1999 545 551
32. M.L. Robertson, D.A. Eastmond, and M.T. Smith Two benzene metabolites, catechol and hydroquinone, produce a synergistic induction of micronuclei and toxicity in cultured human lymphocytes Mutat. Res. 249 1991 201 209
33. A. Rodgman, and C.R. Green Toxic chemicals in cigarette mainstream smoke-hazards and hoopla Beitr. Tabakforsch. Int. 20 2003 481 545
34. H. Sakuma, S. Matsushima, S. Munakata, and S. Sugawara Pyrolysis of chlorogenic acid and rutin Agric. Biol. Chem. 46 1982 1311 1317
35. H. Sakuma, S. Munakata, and S. Sugarawa Volatile products of cellulose pyrolysis Agric. Biol. Chem. 45 1981 443 451
36. S. Sato, T. Ohka, M. Nagao, K. Tsuji, and T. Kosuge Reduction in mutagenicity of cigarette smoke condensate by added sugars Mutat. Res. 60 1979 155 161
37. W.S. Schlotzhauer, and O.T. Chortyk Recent advances in studies on the pyrosynthesis of cigarette smoke constituents J. Anal. Appl. Pyrol. 12 1987 193 222
38. R.K. Sharma, T.S. Fisher, and M.R. Hajaligol Effect of reaction conditions on pyrolysis of chlorogenic acid J. Anal. Appl. Pyrol. 62 2002 281 296
39. C.J. Smith, and C. Hansch The relative toxicity of compounds in mainstream cigarette smoke condensate Food Chem. Toxicol. 38 2000 637 646
40. C. Smith, V. Payne, D.J. Doolittle, A.K. Debnath, T. Lawlor, and C. Hansch Mutagenic activity of a series of synthetic and naturally occurring heterocyclic amines in Salmonella Mutat. Res. 279 1992 61 73
41. R.L. Stedman The chemical composition of tobacco and tobacco smoke Chem. Rev. 68 1968 153 207
42. H.F. Stich, M.P. Rosin, C.H. Wu, and W.D. Powrie A comparative genotoxicity study of chlorogenic acid (3-O-caffeoylquinic acid) Mutat. Res. 90 1981 201 212
43. T. Sugimura, M. Nagao, T. Kawachi, M. Honda, T. Yahagi, Y. Scino, S. Sato, N. Matsukura, T. Matsushima, A. Shirai, M. Sawamura, and H. Matsumoto Mutagens-carcinogens in food, with special reference to highly mutagenic pyrolytic products in broiled food H.H. Hiatt J.D. Watson J.A. Winsten Origins of Human Cancer 1977 Cold Springs Harbor Lab. Cold Spring Harbor 1561 1577
44. H. Tohda, A. Oikawa, T. Kawachi, and T. Sugimura Induction of sister-chromatid exchanges by mutagens from amino acid and protein pyrolysates Mutat. Res. 77 1980 65 69
45. M. Terada, M. Nagao, M. Nakayasu, H. Sakamoto, F. Nakasato, and T. Sugimura Mutagenic activities of heterocyclic amines in Chinese hamster lung cells in culture Environ. Health Perspect. 67 1986 117 119
46. K. Torikaiu, Y. Uwano, T. Nakamori, W. Tarora, and H. Takahashi Study on tobacco components involved in the pyrolytic generation of selected smoke constituents Food Chem. Toxicol. 43 2005 559 568
47. University of Kentucky Tobacco and Health Research Institute, 1990. Research Cigarettes. The University of Kentucky Printing Services, Lexington, KY.
48. D. Veltel, and A. Hoheneder Characterization of cigarette smoke-induced micronuclei in vitro Exp. Toxicol. Pathol. 48 1996 548 550
49. W. von der Hude, S. Kalweit, G. Engelhardt, S. McKiernan, P. Kasper, R. Slacik-Erben, H.G. Miltenburger, N. Honarvar, R. Fahrig, B. Gorlitz, S. Albertini, S. Kirchner, D. Utesch, F. Potter-Locher, H. Stopper, and S. Madle In vitro micronucleus assay with Chinese hamster V79 cells-results of a collaborative study with in situ exposure to 26 chemical substances Mutat. Res. 468 2000 137 163
50. W.W. Weeks Relationships between leaf chemistry and organoleptic properties of tobacco smoke D.L. Davis M.T. Nielsen Tobacco. Production, Chemistry and Technology 1999 Blackwell Science Oxford 304 312
51. J. Whysner, M.V. Reddy, P.M. Ross, M. Mohan, and E.A. Lax Genotoxicity of benzene and its metabolites Mutat. Res. 566 2004 99 130
52. K.-M. Wollin, and B.-D. Görlitz Comparison of genotoxicity of textile dyestuffs in Salmonella mutagenicity assay, in vitro micronucleus assay, and single cell gel/comet assay J. Environ. Pathol. Oncol. 23 2004 267 278