Weekly versus three-weekly cisplatin as an adjunct to radiation therapy in high-risk stage I-IIA cervical cancer after surgery: A randomized comparison of treatment compliance

Journal of the Medical Association of Thailand

Volumn 88, Issue 11, 2005, Pages 1483-1492

  Chumworathayi, Bandit ^a   Suprasert, Prapaporn ^b   Charoenkwan, Kittipat ^b   Srisomboon, Jatupol ^b   Phongnarisorn, Chailert ^b   Siriaree, Sitticha ^b   Cheewakriangkrai, Chalong ^b   Tantipalakorn, Jaruwan ^b   Kiatpeerakul, Chamnan ^b   Pantusart, Aree ^b  

^a KHON KAEN UNIVERSITY   (Thailand)

^b Faculty of Medicine Chiang Mai University   (Thailand)

Author keywords

Cisplatin; Concurrent chemoradiation; High risk cervical cancer

Indexed keywords

CISPLATIN; DEXAMETHASONE; FUROSEMIDE; GRANULOCYTE COLONY STIMULATING FACTOR; LORAZEPAM; MANNITOL; ONDANSETRON; ANTINEOPLASTIC AGENT;

ADENOCARCINOMA; ADENOSQUAMOUS CARCINOMA; ADULT; ANEMIA; ARTICLE; CANCER INVASION; CANCER RADIOTHERAPY; CANCER RISK; CANCER STAGING; CANCER SURGERY; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; CREATININE CLEARANCE; DIARRHEA; DRUG DOSE REGIMEN; ERYTHROCYTE; EXTERNAL BEAM RADIOTHERAPY; FATIGUE; HUMAN; LEUKOPENIA; LIVER FUNCTION; MAJOR CLINICAL STUDY; NAUSEA; NEUTROPENIA; NEUTROPHIL COUNT; PATIENT COMPLIANCE; PERCEPTION DEAFNESS; RANDOMIZED CONTROLLED TRIAL; SQUAMOUS CELL CARCINOMA; THERAPY DELAY; THROMBOCYTE COUNT; THROMBOCYTOPENIA; UTERINE CERVIX CANCER; VIRUS HEPATITIS; VOMITING; ADJUVANT CHEMOTHERAPY; FEMALE; MIDDLE AGED; RADIOGRAPHY; RISK ASSESSMENT; TIME; UTERINE CERVIX TUMOR;

ADENOCARCINOMA; ADULT; ANTINEOPLASTIC AGENTS; CARCINOMA, ADENOSQUAMOUS; CARCINOMA, SQUAMOUS CELL; CHEMOTHERAPY, ADJUVANT; CISPLATIN; FEMALE; HUMANS; MIDDLE AGED; PATIENT COMPLIANCE; RISK ASSESSMENT; TIME FACTORS; UTERINE CERVICAL NEOPLASMS;

EID: 33645215997     PISSN: 01252208     EISSN: 01252208     Source Type: Journal    
DOI: None     Document Type: Article

References (14)

1. Suit H. Assesment of the impact of local control on clinical outcome. Front Radiat Ther Oncol 1996; 29: 17-23.
2. US Department of Health and Human Services. NCI Clinical announcement. Public Health Service, National Institutes of Health, Bethesda, MD, February 1999.
3. Whitney CW, Sause W, Bundy BN, Malfetano JH, Hannigan EV, Fowler WC, et al. A randomized comparison of fluorouracil plus cisplatin versus hydroxyurea as an adjunct to radiation therapy in stages IIB-IVA carcinoma of the cervix with negative para-aortic lymph nodes. A Gynecologic Oncology Group and Southwest Oncology Group study. J Clin Oncol 1999; 17: 1339-48.
4. Morris M, Eifel PJ, Lu J, Grigsby PW, Levenback C, Stevens RE, et al. Pelvic radiation with concurrent chemotherapy versus pelvic and para-aortic radiation for high risk cervical cancer: a randomized Radiation Therapy Oncology Group clinical trial. N Engl J Med 1999; 340: 1137-43.
5. Rose PG, Bundy BN, Watkins EB, Thigpen JT, Deppe G, Maiman MA, et al. Concurrent cisplatin-based chemoradiation improves progression free and overall survival in advanced cervical cancer: results of a randomized Gynecologic Oncology Group study. N Engl J Med 1999; 340: 1144-53.
6. Keys HM, Bundy BN, Stehman FB, Muderspach LI, Chafe WE, Suggs CL III, et al. A comparison of weekly cisplatin during radiation therapy versus irradiation alone each follow by adjuvant hysterectomy in bulky stage IB cervical carcinoma: a radomized trial of the Gynecologic Oncology Group. N Engl J Med 1999; 340: 1154-61.
7. Peters WA III, Liu PY, Barrett RJ, Stock RJ, Monk BJ, Berek JS, et al. Cisplatin and 5-flourouracil plus radiation therapy are superior to radiation therapy as adjunctive in high-risk early stage carcinoma of the cervix after radical hysterectomy and pelvic lymphadenectomy: report of a phase II intergroup study. J Clin Oncol 2000; 18: 1606-13.
8. Rose PG. Chemoradiotherapy for cervical cancer. Eur J Cancer 2002; 38: 270-8.
9. Park TK, Kim SN, Kim SW, Kim GE, Suh CO. Concurrent chemotherapy and radiotherapy in invasive cervical cancer patients with high risk factors. J Korean Med Sci 2000; 15: 436-41.
10. Killackey MA, Boardman L, Carroll DS. Adjuvant chemotherapy and radiation in patients with poor prognosis stage IB-IIA cervical cancer. Gynecol Oncol 1993; 49: 377-9.
11. Thomas GM, Dembo AJ, Myhr T, Black B, Pringle JF, Rawling G. Long-term results of concurrent radiation and chemotherapy for carcinoma of the cervix recurrent after surgery. Int J Gynecol Cancer 1993; 3: 193-8.
12. Pearcey R, Brundage M, Drouin P, Jeffrey J, Johnston D, Lukka H, et al. Phase III trial comparing radical radiotherapy with and without cisplatin chemotherapy in patients with advanced squamous cell cancer of the cervix. J Clin Oncol 2002; 20: 966-72.
13. Benedet JL, Bender H, Jones H III, Ngan HY, Pecorelli S. FIGO staging classifications and clinical practice guidelines in the management of gynecologic cancers. FIGO Committee on Gynecologic Oncology. Int J Gynaecol Obstet 2000; 70: 209-62.
14. Benedet JL, Bender H, Jones H III, Ngan HY, Pecorelli S. FIGO staging classifications and clinical practice guidelines in the management of gynecologic cancers 2003. FIGO Committee on Gynecologic Oncology. http://www.figo.org/. Access date: March 1st, 2004.