Identification and characterization of a G-protein regulatory motif in WAVE1

FEBS Letters

Volumn 580, Issue 8, 2006, Pages 1993-1998

  Song, Kyoung Seob ^a   Peterson, Yuri K ^a   Freidman, Andrew ^a   Blumer, Joe B ^a   Sato, Motohiko ^a   Lanier, S M ^a  

^a LOUISIANA STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Actin polymerization; AGS proteins; Cell migration; G protein; GPR motif; WAVE

Indexed keywords

DOCKING PROTEIN; GROWTH HORMONE RELEASING FACTOR; GUANINE NUCLEOTIDE BINDING PROTEIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; PROTEIN WAVE1; SCAFFOLD PROTEIN; UNCLASSIFIED DRUG;

ACTIN POLYMERIZATION; AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL STRAIN COS7; COMPLEX FORMATION; CONTROLLED STUDY; GENE TARGETING; GENETIC TRANSFECTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN LOCALIZATION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; RAT; SEQUENCE ANALYSIS;

AMINO ACID MOTIFS; AMINO ACID SEQUENCE; ANIMALS; CERCOPITHECUS AETHIOPS; COS CELLS; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; GTP-BINDING PROTEINS; GUANINE NUCLEOTIDES; GUANOSINE 5'-O-(3-THIOTRIPHOSPHATE); MOLECULAR SEQUENCE DATA; PROTEIN BINDING; RATS; SIGNAL TRANSDUCTION; WISKOTT-ALDRICH SYNDROME PROTEIN FAMILY;

ANIMALIA; MAMMALIA;

EID: 33645213382     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2006.02.071     Document Type: Article

References (33)

1. M. Sato, M.J. Cismowski, E. Toyota, A.V. Smrcka, P.A. Lucchesi, W.M. Chilian, and S.M. Lanier Identification of a receptor-independent activator of G protein signaling (AGS8) in ischemic heart and its interaction with Gbetagamma Proc. Natl. Acad. Sci. USA 103 2006 797 802
2. M. Sato, J.B. Blumer, V. Simon, and S.M. Lanier Accessory proteins for G proteins: partners in signaling Annu. Rev. Pharmacol. Toxicol. 46 2006 151 187
3. J.B. Blumer, M.J. Cismowski, M. Sato, and S.M. Lanier AGS proteins: receptor-independent activators of G-protein signaling Trends Pharmacol. Sci. 26 2005 470 476
4. M.J. Cismowski, and S.M. Lanier Activation of heterotrimeric G-proteins independent of a G-protein coupled receptor and the implications for signal processing Rev. Physiol. Biochem. Pharmacol. 155 2005 57 80
5. M.J. Cismowski, A. Takesono, C. Ma, J.S. Lizano, X. Xie, H. Fuernkranz, S.M. Lanier, and E. Duzic Genetic screens in yeast to identify mammalian nonreceptor modulators of G-protein signaling Nat. Biotechnol. 17 1999 878 883
6. A. Takesono, M.J. Cismowski, C. Ribas, M. Bernard, P. Chung, S. Hazard 3rd, E. Duzic, and S.M. Lanier Receptor-independent activators of heterotrimeric G-protein signaling pathways J. Biol. Chem. 274 1999 33202 33205
7. V. Mittal, and M.E. Linder The RGS14 GoLoco domain discriminates among Galphai isoforms J. Biol. Chem. 279 2004 46772 46778
8. K. Sanada, and L.H. Tsai G protein betagamma subunits and AGS3 control spindle orientation and asymmetric cell fate of cerebral cortical progenitors Cell 122 2005 119 131
9. J. Betschinger, and J.A. Knoblich Dare to be different: asymmetric cell division in Drosophila, C. elegans and vertebrates Curr. Biol. 14 2004 674 685
10. Y. Bellaiche, and M. Gotta Heterotrimeric G proteins and regulation of size asymmetry during cell division Curr. Opin. Cell Biol. 17 2005 658 663
11. L. Yao, K. McFarland, P. Fan, Z. Jiang, Y. Inoue, and I. Diamond Activator of G protein signaling 3 regulates opiate activation of protein kinase A signaling and relapse of heroin-seeking behavior Proc. Natl. Acad. Sci. USA 102 2005 8746 8751
12. M.S. Bowers, K. McFarland, R.W. Lake, Y.K. Peterson, C.C. Lapish, M.L. Gregory, S.M. Lanier, and P.W. Kalivas Activator of G protein signaling 3: a gatekeeper of cocaine sensitization and drug seeking Neuron 42 2004 269 281
13. T.L. Bailey, and M. Gribskov Combining evidence using p-values: application to sequence homology searches Bioinformatics 14 1998 48 54
14. S. Eden, R. Rohatgi, A.V. Podtelejnikov, M. Mann, and M.W. Kirschner Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck Nature 418 2002 790 793
15. S. Suetsugu, D. Yamazaki, S. Kurisu, and T. Takenawa Differential roles of WAVE1 and WAVE2 in dorsal and peripheral ruffle formation for fibroblast cell migration Dev Cell 5 2003 595 609
16. S.H. Soderling, K.L. Binns, G.A. Wayman, S.M. Davee, S.H. Ong, T. Pawson, and J.D. Scott The WRP component of the WAVE-1 complex attenuates Rac-mediated signalling Nat. Cell. Biol. 4 2002 970 975
17. T.E. Stradal, K. Rottner, A. Disanza, S. Confalonieri, M. Innocenti, and G. Scita Regulation of actin dynamics by WASP and WAVE family proteins Trends Cell Biol. 14 2004 303 311
18. J.E. Bear, J.F. Rawls, and C.L. Saxe 3rd SCAR, a WASP-related protein, isolated as a suppressor of receptor defects in late Dictyostelium development J. Cell Biol. 142 1998 1325 1335
19. Y.K. Peterson, S. Hazard 3rd, S.G. Graber, and S.M. Lanier Identification of structural features in the G-protein regulatory motif required for regulation of heterotrimeric G-proteins J. Biol. Chem. 277 2002 6767 6770
20. Y.K. Peterson, M.L. Bernard, H. Ma, S. Hazard 3rd, S.G. Graber, and S.M. Lanier Stabilization of the GDP-bound conformation of Gialpha by a peptide derived from the G-protein regulatory motif of AGS3 J. Biol. Chem. 275 2000 33193 33196
21. M.L. Bernard, Y.K. Peterson, P. Chung, J. Jourdan, and S.M. Lanier Selective interaction of AGS3 with G-proteins and the influence of AGS3 on the activation state of G-proteins J. Biol. Chem. 276 2001 1585 1593
22. X. Cao, M.J. Cismowski, M. Sato, J.B. Blumer, and S.M. Lanier Identification and characterization of AGS4: a protein containing three G-protein regulatory motifs that regulate the activation state of Gialpha J. Biol. Chem. 279 2004 27567 27574
23. R.J. Kimple, M.E. Kimple, L. Betts, J. Sondek, and D.P. Siderovski Structural determinants for GoLoco-induced inhibition of nucleotide release by Galpha subunits Nature 416 2002 878 881
24. R.J. Kimple, F.S. Willard, M.D. Hains, M.B. Jones, G.K. Nweke, and D.P. Siderovski Guanine nucleotide dissociation inhibitor activity of the triple GoLoco motif protein G18: alanine-to-aspartate mutation restores function to an inactive second GoLoco motif Biochem. J. 378 2004 801 808
25. A. Adhikari, and S.R. Sprang Thermodynamic characterization of the binding of activator of G protein signaling 3 (AGS3) and peptides derived from AGS3 with G alpha i1 J. Biol. Chem. 278 2003 51825 51832
26. W.W. Ja, and R.W. Roberts In vitro selection of state-specific peptide modulators of G protein signaling using mRNA display Biochemistry 43 2004 9265 9275
27. W.W. Ja, A. Adhikari, R.J. Austin, S.R. Sprang, and R.W. Roberts A peptide core motif for binding to heterotrimeric G protein alpha subunits J. Biol. Chem. 280 2005 32057 32060
28. M. Ghosh, Y.K. Peterson, S.M. Lanier, and A.V. Smrcka Receptor- and nucleotide exchange-independent mechanisms for promoting G protein subunit dissociation J. Biol. Chem. 278 2003 34747 34750
29. N.B. David, C.A. Martin, M. Segalen, F. Rosenfeld, F. Schweisguth, and Y. Bellaiche Drosophila Ric-8 regulates Galphai cortical localization to promote Galphai-dependent planar orientation of the mitotic spindle during asymmetric cell division Nat. Cell. Biol. 7 2005 1083 1090
30. B. Hampoelz, O. Hoeller, S.K. Bowman, D. Dunican, and J.A. Knoblich Drosophila Ric-8 is essential for plasma-membrane localization of heterotrimeric G proteins Nat. Cell Biol. 7 2005 1099 1105
31. H. Wang, K.H. Ng, H. Qian, D.P. Siderovski, W. Chia, and F. Yu Ric-8 controls Drosophila neural progenitor asymmetric division by regulating heterotrimeric G proteins Nat. Cell Biol. 7 2005 1091 1098
32. G.G. Tall, and A.G. Gilman Resistance to inhibitors of cholinesterase 8A catalyzes release of Galphai-GTP and nuclear mitotic apparatus protein (NuMA) from NuMA/LGN/Galphai-GDP complexes Proc. Natl. Acad. Sci. USA 102 2005 16584 16589
33. G.G. Tall, A.M. Krumins, and A.G. Gilman Mammalian Ric-8A (synembryn) is a heterotrimeric Galpha protein guanine nucleotide exchange factor J. Biol. Chem. 278 2003 8356 8362