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Volumn 14, Issue 1, 2006, Pages 37-41

Expression of thymidylate synthase in primary colorectal adenocarcinoma

Author keywords

5 fluorouracil; Gene expression; Gene polymorphism; Immunohistochemical staining; Thymidylate synthase

Indexed keywords

DNA; FLUOROURACIL; MESSENGER RNA; RNA; THYMIDYLATE SYNTHASE;

EID: 33645167950     PISSN: 15412016     EISSN: 15334058     Source Type: Journal    
DOI: 10.1097/01.pai.0000154057.41274.6b     Document Type: Article
Times cited : (12)

References (10)
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  • 2
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    • Discrepancies between the gene expression, protein expression, and enzymatic activity of thymidylate synthase and dihadropyrimidine dehydrogenase in human gastrointestinal cancers and adjacent normal mucosa
    • Miyamoto S, Ochiai A, Narikazy B, et al. Discrepancies between the gene expression, protein expression, and enzymatic activity of thymidylate synthase and dihadropyrimidine dehydrogenase in human gastrointestinal cancers and adjacent normal mucosa. Int J Oncol. 2001;18:705-713.
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    • Miyamoto, S.1    Ochiai, A.2    Narikazy, B.3
  • 3
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    • Thymidylate synthase and dihydropyrimidine dehydrogenase mRNA expression levels: Predictors for survival in colorectal cancer patients receiving adjuvant 5-fluorouracil
    • Kornmann M, Schwabe W, Sander S, et al. Thymidylate synthase and dihydropyrimidine dehydrogenase mRNA expression levels: predictors for survival in colorectal cancer patients receiving adjuvant 5-fluorouracil. Clin Cancer Res. 2003;6:1322-1327.
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    • Kornmann, M.1    Schwabe, W.2    Sander, S.3
  • 4
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    • Different lengths of a polymorphic repeat sequence in the thymidylate synthase gene affect translational efficiency but not its gene expression
    • Kawakami K, Salonga D, Park JM, et al. Different lengths of a polymorphic repeat sequence in the thymidylate synthase gene affect translational efficiency but not its gene expression. Clin Cancer Res. 2001;7:4096-4101.
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  • 5
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    • Merkelbach-Bruse S, Mathiak HV, Sangueldolce R, et al. Associations between polymorphisms in the thymidylate synthase gene, the expression of thymidylate synthase mRNA and microsatellite instability phenotype of colorectal cancer. Oncol Rep. 2004;11:839-843.
    • (2004) Oncol Rep , vol.11 , pp. 839-843
    • Merkelbach-Bruse, S.1    Mathiak, H.V.2    Sangueldolce, R.3
  • 6
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    • Polymorphic tandem repeats in the thymidylate synthase gene is associated with its protein expression in human gastrointestinal cancers
    • Kawakami K, Omura K, Kanchira E, et al. Polymorphic tandem repeats in the thymidylate synthase gene is associated with its protein expression in human gastrointestinal cancers. Anticancer Res. 1999;19:3249-3252.
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  • 7
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    • Polymorphism in the thymidylate synthase promoter enhancer region is not an efficacious marker for tumor sensitivity to 5-fluorouracil-based oral adjuvant chemotherapy in colorectal cancer
    • Tsuji T, Hidaka S, Sawai T, et al. Polymorphism in the thymidylate synthase promoter enhancer region is not an efficacious marker for tumor sensitivity to 5-fluorouracil-based oral adjuvant chemotherapy in colorectal cancer. Clin Cancer Res. 2003;9:3700-3704.
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  • 8
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    • Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase and thymidine phosphorylase
    • Salong D, Danenberg KD, Johnson M, et al. Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase and thymidine phosphorylase. Clin Cancer Res. 2000;6:1322-1327.
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    • (2002) J Clin Oncol , vol.20 , pp. 1721-1728
    • Edler, D.1    Glimelius, B.2    Hallström, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.