HLA class II genetic diversity in southern Tunisia and the Mediterranean area

International Journal of Immunogenetics

Volumn 33, Issue 2, 2006, Pages 93-103

  Abdennaji Guenounou, B ^a   Loueslati, B Yacoubi ^b   Buhler, S ^c   Hmida, S ^d   Ennafaa, H ^b   Khodjet Elkhil, H ^b   Moojat, N ^d   Dridi, A ^d   Boukef, K ^d   Ben Ammar Elgaaied, A ^b   Sanchez Mazas, A ^c  

^a Regional Center of Blood Transfusion   (Tunisia)

^b FACULTÉ DES SCIENCES DE TUNIS   (Tunisia)

^c UNIVERSITY OF GENEVA   (Switzerland)

^d National Blood Transfusion Center   (Tunisia)

Author keywords

[No Author keywords available]

Indexed keywords

HLA ANTIGEN CLASS 2; HLA DQB1 ANTIGEN; HLA DR ANTIGEN;

ARAB; ARTICLE; CHROMOSOME ANALYSIS; CONTROLLED STUDY; DNA POLYMORPHISM; GENE FREQUENCY; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HAPLOTYPE; HLA SYSTEM; HUMAN; LANGUAGE; NORMAL HUMAN; NORTH AFRICA; POPULATION GENETICS; POPULATION RESEARCH; POPULATION SIZE; PRIORITY JOURNAL; SOUTHERN EUROPE; TUNISIA; Y CHROMOSOME;

ALLELES; GENE FREQUENCY; GENETICS, POPULATION; HAPLOTYPES; HLA-DQ ANTIGENS; HLA-DR ANTIGENS; HUMANS; MEDITERRANEAN REGION; TUNISIA; VARIATION (GENETICS);

EID: 33645131019     PISSN: 17443121     EISSN: 1744313X     Source Type: Journal    
DOI: 10.1111/j.1744-313X.2006.00577.x     Document Type: Article

References (62)

1. Ameur A. 1960 La Tunisie à travers l'histoire. El Hadi Abdelghani Librairie Ennajah, Tunis, Tunisia.
2. Arnaiz-Villena A. Benmamar D. Alvarez M. Diaz-Campos N. Varela P. Gomez-Casado E. Martinez-Laso J. 1995 HLA allele and haplotype frequencies in Algerians. Relatedness to Spaniards and Basques. Human Immunology 43 259.
3. Arnaiz-Villena A. Dimitroski K. Pacho A. Moscoso J. Gomez-Casado E. Silvera-Redondo C. Varela P. Blagoevska M. Zdravkovska V. Martinez-Laso J. 2001 HLA genes in Macedonians and the sub-Saharan origin of the Greeks. Tissue Antigens 57 118.
4. Arnaiz-Villena A. Gomez-Casado E. Martinez-Laso J. 2002 Population genetic relationships between Mediterranean populations determined by HLA allele distribution and a historic perspective. Tissue Antigens 60 111.
5. Arredi B. Poloni E.S. Paracchini S. Zerjal T. Fathallah D.M. Makrelouf M. Pascali V.L. Novelletto A. Tyler-Smith C. 2004 A predominantly neolithic origin for Y-chromosomal DNA variation in North Africa. American Journal of Human Genetics 75 338.
6. Ayed K. Barddi R. Geburer L. Gorgi Y. Betel H. 1987 HLA-A, B, C and DR antigens in a sample of the Tunisian population. Tissue Antigens 29 225.
7. Bias W. Nuwayri-Salti N. Wood W. Cissell B. Berger S. Schmeckpeper B. 1997 A comparison of HLA-DRB1 and -DQB1 alleles in three Lebanese villages reproductively isolated by geography and religion. In Proceedings of the 12th International Histocompatibility Workshop and Conference (ed. by Charron D. p. 189. EDK Paris.
8. Blanc M. Sanchez-Mazas A. van Blyenburgh N. Sevin A. Pison G. Langaney A. 1990 Interethnic genetic differentiation: GM polymorphism in eastern Senegal. American Journal of Human Genetics 46 383.
9. Bodmer W.F. 1987 The HLA system: structure and function. Journal of Clinical Pathology 40 948.
10. Bosch E. Calafell F. Comas D. Oefner P.J. Underhill P.A. Bertranpetit J. 2001 High-resolution analysis of human Y-chromosome variation shows a sharp discontinuity and limited gene flow between northwestern Africa and the Iberian Peninsula. American Journal of Human Genetics 68 1019.
11. Bosch E. Calafell F. Perez-Lezaun A. Comas D. Mateu E. Bertranpetit J. 1997 Population history of North Africa: evidence from classical genetic markers. Human Biology 69 295.
12. Buyse I. Dacorte R. Baens M. Cuppens H. Semana G. Edmonds M.P. Marynem M.P. Cassiman J.J. 1993 Rapid DNA typing of class II antigens using the polymerase chain reaction and reverse dot blot hybridization. Tissue Antigens 41 1.
13. Clayton J. Lonjou C. Whittle D. 1997 Allele and haplotype frequencies for HLA loci in various ethnic groups. In Genetic Diversity of HLA: Functional and Medical Implication. Proceedings of the 12th International Histocompatibility Workshop and Conference (Paris, June 1996) (ed. by Charron D. p. 665. EDK Paris.
14. Comas D. Calafell F. Mateu E. Perez-Lezaun A. Bertranpetit J. 1998 HLA evidence for the lack of genetic heterogeneity in Basques. Annals of Human Genetics 62 123.
15. Contu L. Arras M. Carcassi C. La Nasa G. Mulargia M. 1992 HLA structure of the Sardinian population: a haplotype study of 551 families. Tissue Antigens 40 165.
16. Djoulah S. Sanchez-Mazas A. Khalil I. Benhamamouch S. Degos L. Deschamps I. Hors J. 1994 HLA-DRB1, DQA1 and DQB1 DNA polymorphisms in healthy Algerian and genetic relationships with other populations. Tissue Antigens 43 102.
17. El Chenawi F. Djoulah S. Abbas F. Mahmoud L. Lapperière J. Hors J. Charron D. Sanchez-Mazas A. 1996 HLA class II DRB1 and DQB1 polymorphisms in the Egyptian population of Siwa. Human Immunology 47 142.
18. Ewens W.J. 1972 The sampling theory of selectively neutral alleles. Theoretical Population Biology 3 87.
19. Gomez-Casado E. del Moral P. Martinez-Laso J. Garcia-Gomez A. Allende L. Silvera-Redondo C. Longas J. Gonzalez-Hevilla M. Kandil M. Zamora J. Arnaiz-Villena A. 2000 HLA genes in Arabic-speaking Moroccans: close relatedness to Berbers and Iberians. Tissue Antigens 55 239.
20. Grubic Z. Zunec R. Cecuk-Jelicic E. Kerhin-Brkljacic V. Kastelan D. et al. 1998 HLA class II gene and haplotype diversity in the population of the island of Hvar, Croatia. Collegium Antropologicum 22 157.
21. Grubic Z. Zunec R. Naipal A. Kastelan A. Giphart M.J. 1995 Molecular analysis of HLA class II polymorphism in Croatians. Tissue Antigens 46 293.
22. Hafez M. El Chennawi F. 1986 HLA-antigens in the Egyptian population. Forensic Science International 31 241.
23. Hmida S. Gauthier A. Dridi A. Quillivic F. Genetet B. Boukef K. Semana G. 1995 HLA class II gene polymorphism in Tunisians. Tissue Antigens 45 63.
24. Hors J. El Chenawi F. Djoulah S. Hafez M. Abbas F. El Borai M.-H. et al. 1997 HLA in North African populations: 12th International Histocompatibility Workshop: NAFR report. In Genetic Diversity of HLA: Functional and Medical Implication. Proceedings of the 12th International Histocompatibility Workshop and Conference (Paris, June 1996) (ed. by Charron D. p. 328. EDK Paris.
25. Hristova-Dimceva A. Verduijn W. Schipper R.F. Schreuder G.M. 2000 HLA-DRB and -DQB1 polymorphism in the Macedonian population. Tissue Antigens 55 53.
26. Imanishi T. Akaza T. Kimura A. Tokunaga K. Gojobori T. 1992 Allele and haplotype frequencies for HLA and complement loci in various ethnic groups. In HLA 1991 (ed. by Tsuji K. Aizawa M. Sasazuki T. p. 1065. Oxford University Press Oxford.
27. Izaabel H. Sanchez-Mazas A. Caillat-Zuccman S. Beaurin G. Akhayat O. Bach J. Garchon H. 1996 Three DRB1-DQA1-DQB1 haplotypes account for 45% of total haplotype frequencies in Moroccans from the Souss Area. Human Immunology 47 57.
28. Jenhani F. Badri R. Gorgi Y. Ayed K. Chammaki S. Boukhris R. 1989 Polymorphisme HLA, A, B, C, DR, C4, Bf chez les diabétiques insulinodépendants dans la population tunisienne. Annales de Biologie Clinique 47 23.
29. Julien C.A. 1961 Histoire de l'Afrique Du Nordiska. Payot Paris.
30. Khaldoun I. 1925-1956 Histoire des Berbères et des dynasties musulmanes de l'Afrique. Librairie Orientaliste Paul Geuthner Paris.
31. Khodjet El Khil H. Triki Marrakchi R. Yacoubi Loueslati B. Langaney A. Fellous M. Benammar Elgaaied A. 2001 Y chromosome microsatellite variation in three populations of Jerba Island (Tunisia). Annals of Human Genetics 65 263.
32. Kruskal J.B. 1964 Nonmetric multidimensional scaling: a numerical method. Psychometrika 29 28.
33. Lampis R. Morelli L. De Virgiliis S. Congia M. Cucca F. 2000 The distribution of HLA class II haplotypes reveals that the Sardinian population is genetically differentiated from the other Caucasian populations. Tissue Antigens 56 515.
34. Lebon G. 1884 ) La civilisation des Arabes. Librairie Firmin Diderot et Cie Paris.
35. Mack S.J. Meyer D. Single R.M. Sanchez-Mazas A. Thomson G. Erlich H.A. in press 13th International Histocompatibility Workshop Anthropology / Human Genetic Diversity Joint Report - Chapter 1: Introduction and Overview. In HLA 2002: Immunobiology of the Human MHC (ed. by Hansen J. A. Dupont B. IHWG Press Seattle.
36. Mantel G. 1967 The detection of disease clustering and a generalized regression approach. Cancer Research 27 209.
37. Meyer D. Thomson G. 2001 How selection shapes variation of the human major histocompatibility complex: a review. Annals of Human Genetics 65 1.
38. Miller S.A. Dykes D.D. Polesky H.F. 1988 A sampling salting out procedure for extraction DNA from human nucleated cells. Nucleic Acid Research 16 1215.
39. Muro M. Marin L. Torio A. Moya-Quiles M.R. Minguela A. Rosique-Roman J. Sanchis M.J. Garcia-Calatayud M.C. Garcia-Alonso A.M. Alvarez-Lopez M.R. 2001 HLA polymorphism in the Murcia population (Spain): in the cradle of the archaeologic Iberians. Human Immunology 62 910.
40. Oumhani K. Canossi A. Piancatelli D. Di Rocco M. Del Beato T. Liberatore G. et al. 2002 Sequence-based analysis of the HLA-DRB1 polymorphism in Metalsa Berber and Chaouya Arabic-speaking groups from Morocco. Human Immunology 63 129.
41. Piazza A. Lonjou C. 1997 HLA in Europe and in the Mediterranean countries. In Genetic Diversity of HLA: Functional and Medical Implication. Proceedings of the 12th International Histocompatibility Workshop and Conference (Paris, June 1996) (ed. by Charron D. p. 374. EDK Paris.
42. Plaza S. Calafell F. Helal A. Bouzerna N. Lefranc G. Bertranpetit J. Comas D. 2003 Joining the pillars of Hercules: mtDNA sequences show multidirectional gene flow in the western Mediterranean. Annals of Human Genetics 67 312.
43. Reynolds J. Weir B.S. Cockerham C.C. 1983 Estimation for the coancestry coefficient: basis for a short-term genetic distance. Genetics 105 767.
44. Rohlf F.J. 1972 An empirical comparison of three ordination techniques in numerical taxonomy. Systematic Zoology 21 271.
45. Rohlf F.J. 2000 ) ntsys - pc, Numerical Taxonomy and Multivariate Analysis System. Place: 2.1 Edn Exeter Software. Applied Biostatistics, Inc Stony Brook, New York.
46. Roitberg-Tambur A. Witt C.S. Friedmann A. Safirman C. Sherman L. Battat S. Nelken D. Brautbar C. 1995 Comparative analysis of HLA polymorphism at the serologic and molecular level in Moroccan and Ashkenazi Jews. Tissue Antigens 46 104.
47. Ruhlen M. 1987 A Guide to the World's Languages, Vol. 1 Edward Arnold London.
48. Sanchez-Mazas A. in press 13th International Histocompatibility Workshop Anthropology / Human Genetic Diversity Joint Report - Chapter 7: HLA genetic diversity of the 13th IHWC population data relative to worldwide linguistic families. In HLA 2002: Immunobiology of the Human MHC (ed. by Hansen J. A. Dupont B. IHWG Press Seattle.
49. Sanchez-Mazas A. 2002 HLA data analysis in anthropology: basic theory and practice. 16th European Histocompatibility Conference, Strasbourg, France. European Federation for Immunogenetics (EFI), Strasbourg, France. p. 68.
50. Sanchez-Mazas A. Djoulah S. Busson M. Le Monnier de Gouville I. Poirier J.C. Dehay C. et al. 2000 A linkage disequilibrium map of the MHC region based on the analysis of 14 loci haplotypes in 50 French families. European Journal of Human Genetics 8 33.
51. Sanchez-Mazas A. 2001 African diversity from the HLA point of view: influence of genetic drift, geography, linguistics, and natural selection. Human Immunology 62 937.
52. Schneider S. Roessli D. Excoffier L. 2000 arlequin: A Software for Population Genetics Data Analysis. Place: 2.0 Edn Genetics and Biometry Laboratory. Department of Anthropology, University of Geneva, Geneva, Switzerland.
53. Seielstad M.T. Minch E. Cavalli-Sforza L.L. 1998 Genetic evidence for a higher female migration rate in humans. Nature Genetics 20 278.
54. Simoni L. Gueresi P. Pettener D. Barbujani G. 1999 Patterns of gene flow inferred from genetic distances in the Mediterranean region. Human Biology 71 399.
55. Single R. Meyer D. Mack S.J. Lancaster A. Nelson M.P. Erlich H. Fernandez Viña M. Thomson G. in press-a 13th International Histocompatibility Workshop Anthropology/ Human Genetic Diversity Joint Report - Chapter 5: Haplotype frequencies and linkage disequilibrium among classical HLA genes. In HLA 2002: Immunobiology of the Human MHC (ed. by Hansen J. A. Dupont B. IHWG Press Seattle.
56. Single R. Meyer D. Mack S.J. Lancaster A. Nelson M.P. Fernandez Viña M. Erlich H. Thomson G. in press b 13th International Histocompatibility Workshop Anthropology/ Human Genetic Diversity Joint Report - Chapter 4: Single locus polymorphism of classical HLA genes. In HLA 2002: Immunobiology of the Human MHC (ed. by Hansen J. A. Dupont B. IHWG Press Seattle.
57. Stravopoulos-Giokas C. Papasteriades C. Polymenidis A. Naumova E. Saruhan G. Varnavidou A. 1997 HLA in MEDI region populations: 12th International Histocompatibility Workshop MEDI Region report. In Genetic Diversity of HLA: Functional and Medical Implication. Proceedings of the 12th International Histocompatibility Workshop and Conference (Paris, June 1996) (ed. by Charron D. p. 323. EDK Paris.
58. Tiilikainen A. Fischer G. Grubic Z. Gyòdi E. Ivaskova E. Jungerman M. et al. 1997 Anthropological features of the East European region. In Genetic Diversity of HLA: Functional and Medical Implication. Proceedings of the 12th International Histocompatibility Workshop and Conference (Paris, June 1996) (ed. by Charron D. p. 307. EDK Paris.
59. Tlatli S.E. 1967 Djerba l'île des Lotophages. Ceres Production, Tunis, Tunisia.
60. Watterson G.A. 1978 The homozygosity test of neutrality. Genetics 88 405.
61. Wilder J.A. Kingan S.B. Mobasher Z. Pilkington M.M. Hammer M.F. 2004 Global patterns of human mitochondrial DNA and Y-chromosome structure are not influenced by higher migration rates of females versus males. Nature Genetics 36 1122.
62. Yacoubi Loveslati B. Sanchez-Mazas A. Ennafaa H. Marrakchi R. Dugoujon J.-M. Lefranc M.-P. Ben Ammar Elgaaied A. 2001 A study of Gm allotypes and immunoglobulin heavy gamma IGHG genes in Berbers, Arabs and sub-Saharan Africans from Jerba Island, Tunisia. European Journal of Immunogenetics 28 531.