Inhibition of human cytochrome P450 isoforms and NADPH-CYP reductase in vitro by 15 herbal medicines, including Epimedii herba

Journal of Clinical Pharmacy and Therapeutics

Volumn 31, Issue 1, 2006, Pages 83-91

  Liu, K H ^a   Kim, M J ^a   Jeon, B H ^b   Shon, J H ^a   Cha, I J ^a   Cho, K H ^a   Lee, S S ^a,c   Shin, J G ^a,c  

^a Inje University College of Medicine   (South Korea)

^b Wonkwang University   (South Korea)

^c Inje University College of Medicine   (South Korea)

Author keywords

Cytochrome P450; Drug herb interaction; Herbal medicines; Inhibition

Indexed keywords

ANGELICAE GIGANTIS RADIX EXTRACT; ATRACTYLODIS MACROCEPHALAE RHIZOMA EXTRACT; CAMPESTEROL; CARBAMAZEPINE; CHLORPROPAMIDE; CHLORZOXAZONE; CYTOCHROME P450 ISOENZYME; DEXTROMETHORPHAN; DIOSCOREAE RHIZOMA EXTRACT; EPIMEDII HERBA EXTRACT; EUCOMMIAE CORTEX EXTRACT; GINSENG EXTRACT; GLYCYRRHIZA EXTRACT; HERBACEOUS AGENT; LANSOPRAZOLE; LEONURI HERBA EXTRACT; LIRIOPSIS TUBER EXTRACT; LYCII FRUCTUS EXTRACT; MORINDAE RADIX EXTRACT; PARACETAMOL; PERSICAE SEMEN EXTRACT; PHENACETIN; PLANT EXTRACT; PORIA COCOS EXTRACT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE FERRIHEMOPROTEIN REDUCTASE; REHMANNIAE RADIX EXTRACT; SALVIAE MILTIORRHIZAE RADIX EXTRACT; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANGELICAE GIGANTIS RADIX; ARTICLE; ATRACTYLODIS MACROCEPHALAE RHIZOMA; CONTROLLED STUDY; DIOSCOREAE RHIZOMA; DRUG HYDROXYLATION; DRUG INHIBITION; DRUG ISOLATION; DRUG POTENCY; ENZYME ACTIVITY; ENZYME INHIBITION; EPIMEDII HERBA; EUCOMMIAE CORTEX; FREEZE DRYING; GINSENG; GLYCYRRHIZA; HERB DRUG INTERACTION; HERBAL MEDICINE; HUMAN; HUMAN TISSUE; IC 50; LEONURI HERBA; LIRIOPIS TUBER; LIVER MICROSOME METABOLISM; LYCII FRUCTUS; MORINDAE RADIX; PERSICAE SEMEN; PHARMACOGENOMICS; PORIA COCOS; PROTEIN VARIANT; REHMANNIA ROOT; SALVIAE MILTIORRHIZAE RADIX;

ANGIOSPERMS; BASIDIOMYCOTA; CYTOCHROME P-450 ENZYME SYSTEM; DRUG INTERACTIONS; DRUGS, CHINESE HERBAL; HUMANS; KOREA; MICROSOMES, LIVER; NADPH-FERRIHEMOPROTEIN REDUCTASE; PLANT EXTRACTS; PLANTS, MEDICINAL; QUERCETIN;

EID: 33645126398     PISSN: 02694727     EISSN: 13652710     Source Type: Journal    
DOI: 10.1111/j.1365-2710.2006.00706.x     Document Type: Article

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