메뉴 건너뛰기




Volumn 189, Issue 7, 2005, Pages 1435-1448

Genetics of asthma and atopy: How many genes?;Génétique de l'asthme et de l'atopie: Combien de gènes identifiés?

Author keywords

Asthma; Genome; Hypersensitivity, immediate; Polymorphism, genetic

Indexed keywords


EID: 33645108282     PISSN: 00014079     EISSN: None     Source Type: Journal    
DOI: 10.1016/s0001-4079(19)33453-3     Document Type: Review
Times cited : (4)

References (50)
  • 1
    • 0032705972 scopus 로고    scopus 로고
    • Generational increase of self-reported first attack of asthma in fifteen industrialized countries. European Community Respiratory Health Survey (ECRHS)
    • SUNYER J., ANTO M.M., TOBIAS A., BURNEY P. - Generational increase of self-reported first attack of asthma in fifteen industrialized countries. European Community Respiratory Health Survey (ECRHS). Eur. Respir. J., 1999, 14, 885-891.
    • (1999) Eur. Respir. J. , vol.14 , pp. 885-891
    • Sunyer, J.1    Anto, M.M.2    Tobias, A.3    Burney, P.4
  • 4
    • 0034017303 scopus 로고    scopus 로고
    • Relationships of active smoking to asthma and asthma severity in the EGEA study. Epidemiological study on the Genetics and Environment of Asthma
    • SIROUX V., PIN I., ORYSZCZYN M.P., LE MOUAL N., KAUFFMANN F. - Relationships of active smoking to asthma and asthma severity in the EGEA study. Epidemiological study on the Genetics and Environment of Asthma. Eur. Respir. J., 2000, 15, 470-477.
    • (2000) Eur. Respir. J. , vol.15 , pp. 470-477
    • Siroux, V.1    Pin, I.2    Oryszczyn, M.P.3    Le Moual, N.4    Kauffmann, F.5
  • 5
    • 0035685413 scopus 로고    scopus 로고
    • Diet and obstructive lung diseases
    • ROMIEU I. and TRENGA C. - Diet and obstructive lung diseases. Epidemiol. Rev., 2001, 23, 268-287.
    • (2001) Epidemiol. Rev. , vol.23 , pp. 268-287
    • Romieu, I.1    Trenga, C.2
  • 7
    • 0024417450 scopus 로고
    • Hay fever hygiene and household size
    • STRACHAN D.P. - Hay fever hygiene and household size. Bmj., 1989, 299, 1259-1260.
    • (1989) Bmj , vol.299 , pp. 1259-1260
    • Strachan, D.P.1
  • 8
    • 0032720874 scopus 로고    scopus 로고
    • The importance of genetic influences in asthma
    • Los H., KOPPELMAN G.H., POSTMA D.S. - The importance of genetic influences in asthma. Eur. Respir. J., 1999, 14, 1210-1227.
    • (1999) Eur. Respir. J. , vol.14 , pp. 1210-1227
    • Los, H.1    Koppelman, G.H.2    Postma, D.S.3
  • 9
    • 0033678658 scopus 로고    scopus 로고
    • Familial aggregation and heritability of asthma-associated quantitative traits in a population-based sample of nuclear families
    • PALMER L.J., BURTON P.R., JAMES A.L., MUSK A.W., COOKSON W.O. - Familial aggregation and heritability of asthma-associated quantitative traits in a population-based sample of nuclear families. Eur. J. Hum. Genet., 2000, 8, 853-860.
    • (2000) Eur. J. Hum. Genet. , vol.8 , pp. 853-860
    • Palmer, L.J.1    Burton, P.R.2    James, A.L.3    Musk, A.W.4    Cookson, W.O.5
  • 10
    • 0035021432 scopus 로고    scopus 로고
    • Familial aggregation and heritability of adult lung function: Results from the Busselton Health Study
    • PALMER L.J., KNUIMAN M.W., DIVITINI M.L., BURTON P.R., JAMES A.L. et al. - Familial aggregation and heritability of adult lung function: results from the Busselton Health Study. Eur. Respir. J., 2001, 17, 696-702.
    • (2001) Eur. Respir. J. , vol.17 , pp. 696-702
    • Palmer, L.J.1    Knuiman, M.W.2    Divitini, M.L.3    Burton, P.R.4    James, A.L.5
  • 11
    • 7744229941 scopus 로고    scopus 로고
    • Familial correlations and inter-relationships of four asthma-associated quantitative phenotypes in 320 French EGEA families ascertained through asthmatic probands
    • BOUZIGON E., CHAUDRU V., CARPENTIER A.S., DIZIER M.H., ORYSZCZYN M.P. et al. - Familial correlations and inter-relationships of four asthma-associated quantitative phenotypes in 320 French EGEA families ascertained through asthmatic probands. Eur. J. Hum. Genet., 2004, 12, 955-963.
    • (2004) Eur. J. Hum. Genet. , vol.12 , pp. 955-963
    • Bouzigon, E.1    Chaudru, V.2    Carpentier, A.S.3    Dizier, M.H.4    Oryszczyn, M.P.5
  • 12
    • 0031954851 scopus 로고    scopus 로고
    • The genetics of asthma Maternal effects in atopic disease
    • discussion 65-56
    • MOFFATT M.F, COOKSON W.O. - The genetics of asthma Maternal effects in atopic disease Clin. Exp. Allergy, 1998, 28 Suppl 1, 56-61; discussion 65-56.
    • (1998) Clin. Exp. Allergy , vol.28 , Issue.SUPPL. 1 , pp. 56-61
    • Moffatt, M.F.1    Cookson, W.O.2
  • 14
    • 0035085576 scopus 로고    scopus 로고
    • Gibbs sampling-based segregation analysis of asthma-associated quantitative traits in a population-based sample of nuclear families
    • PALMER L.J., COOKSON W.O., JAMES A.L., MUSK A.W., BURTON P.R. - Gibbs sampling-based segregation analysis of asthma-associated quantitative traits in a population-based sample of nuclear families. Genet. Epidemiol., 2001, 20, 356-372.
    • (2001) Genet. Epidemiol. , vol.20 , pp. 356-372
    • Palmer, L.J.1    Cookson, W.O.2    James, A.L.3    Musk, A.W.4    Burton, P.R.5
  • 15
    • 1942494043 scopus 로고    scopus 로고
    • Association studies for asthma and atopic diseases: A comprehensive review of the literature
    • HOFFJAN S., NICOLAE D., OBER C. - Association studies for asthma and atopic diseases: a comprehensive review of the literature. Respir. Res., 2003, 4, 14.
    • (2003) Respir. Res. , vol.4 , pp. 14
    • Hoffjan, S.1    Nicolae, D.2    Ober, C.3
  • 16
    • 15944397667 scopus 로고    scopus 로고
    • The role of genetics in the development of asthma and atopy
    • BLUMENTHAL M.N. - The role of genetics in the development of asthma and atopy. Curr. Opin. Allergy Clin. Immunol., 2005, 5, 141-145.
    • (2005) Curr. Opin. Allergy Clin. Immunol. , vol.5 , pp. 141-145
    • Blumenthal, M.N.1
  • 17
    • 1942499447 scopus 로고    scopus 로고
    • Time to draw breath: Asthma-susceptibility genes are Identified
    • WILLS-KARP M., EWART S.L. - Time to draw breath: asthma-susceptibility genes are Identified. Nat. Rev. Genet., 2004, 5, 376-387.
    • (2004) Nat. Rev. Genet. , vol.5 , pp. 376-387
    • Wills-Karp, M.1    Ewart, S.L.2
  • 18
    • 0036237522 scopus 로고    scopus 로고
    • Genomics and proteomics of allergic disease
    • TODA M., ONO S.J. - Genomics and proteomics of allergic disease. Immunology, 2002, 106, 1-10.
    • (2002) Immunology , vol.106 , pp. 1-10
    • Toda, M.1    Ono, S.J.2
  • 19
    • 0037329595 scopus 로고    scopus 로고
    • Learning from discrepancies: CD14 polymorphisms, atopy and the endotoxin switch
    • VERCELLI D. - Learning from discrepancies: CD14 polymorphisms, atopy and the endotoxin switch. Clin. Exp. Allergy, 2003, 33, 153-155.
    • (2003) Clin. Exp. Allergy , vol.33 , pp. 153-155
    • Vercelli, D.1
  • 22
    • 1542721504 scopus 로고    scopus 로고
    • Toll-like receptor 2 as a major gene for asthma in children of European farmers
    • EDER W., KLIMECKI W., YU L., VON MUTIUS E., RIEDLER J. et al. - Toll-like receptor 2 as a major gene for asthma in children of European farmers. J. Allergy Clin. Immunol., 2004, 113, 482-488.
    • (2004) J. Allergy Clin. Immunol. , vol.113 , pp. 482-488
    • Eder, W.1    Klimecki, W.2    Yu, L.3    Von Mutius, E.4    Riedler, J.5
  • 23
    • 0942276431 scopus 로고    scopus 로고
    • IL10 gene polymorphisms are associated with asthma phenotypes in children
    • LYON H., LANGE C., LAKE S., SILVERMAN E.K., RANDOLPH A.G. et al. - IL10 gene polymorphisms are associated with asthma phenotypes in children. Genet. Epidemiol., 2004, 26, 155-165.
    • (2004) Genet. Epidemiol. , vol.26 , pp. 155-165
    • Lyon, H.1    Lange, C.2    Lake, S.3    Silverman, E.K.4    Randolph, A.G.5
  • 24
    • 0030903861 scopus 로고    scopus 로고
    • A genome-wide search for asthma susceptibility loci in ethnically diverse populations. The Collaborative Study on the Genetics of Asthma (CSGA)
    • A genome-wide search for asthma susceptibility loci in ethnically diverse populations. The Collaborative Study on the Genetics of Asthma (CSGA). Nat. Genet., 1997, 15, 389-392.
    • (1997) Nat. Genet. , vol.15 , pp. 389-392
  • 25
    • 0033563231 scopus 로고    scopus 로고
    • A genome-wide search for linkage to asthma
    • German Asthma Genetics Group
    • WJST M., FISCHER G., IMMERVOLL T., JUNG M., SAAR K. et al. - A genome-wide search for linkage to asthma. German Asthma Genetics Group. Genomics., 1999, 58, 1-8.
    • (1999) Genomics , vol.58 , pp. 1-8
    • Wjst, M.1    Fischer, G.2    Immervoll, T.3    Jung, M.4    Saar, K.5
  • 26
    • 0035205425 scopus 로고    scopus 로고
    • A genomewide search for quantitative-trait loci underlying asthma
    • Xu X., FANG Z., WANG B., CHEN C., GUANG W. et al. - A genomewide search for quantitative-trait loci underlying asthma. Am. J. Hum. Genet., 2001, 69, 1271-1277.
    • (2001) Am. J. Hum. Genet. , vol.69 , pp. 1271-1277
    • Xu, X.1    Fang, Z.2    Wang, B.3    Chen, C.4    Guang, W.5
  • 27
    • 0037173639 scopus 로고    scopus 로고
    • Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness
    • VAN EERDEWEGH P., LITTLE R.D., DUPUIS J., DEL MASTRO R.G., FALLS K. et al. - Association of the ADAM33 gene with asthma and bronchial hyperresponsiveness. Nature. 2002, 418, 426-430.
    • (2002) Nature , vol.418 , pp. 426-430
    • Van Eerdewegh, P.1    Little, R.D.2    Dupuis, J.3    Del Mastro, R.G.4    Falls, K.5
  • 28
    • 0036479817 scopus 로고    scopus 로고
    • A genome-wide linkage analysis of orchard grass-sensitive childhood seasonal allergic rhinitis in Japanese families
    • YOKOUCHI Y., SHIBASAKI M., NOGUCHI E., NAKAYAMA J., OHTSUKI T. et al. - A genome-wide linkage analysis of orchard grass-sensitive childhood seasonal allergic rhinitis in Japanese families. Genes Immun., 2002, 3, 9-13.
    • (2002) Genes Immun. , vol.3 , pp. 9-13
    • Yokouchi, Y.1    Shibasaki, M.2    Noguchi, E.3    Nakayama, J.4    Ohtsuki, T.5
  • 30
    • 19944432535 scopus 로고    scopus 로고
    • A genome-wide screen on the genetics of atopy in a multiethnic European population reveals a major atopy locus on chromosome 3q21.3
    • KURZ T., ALTMUELLER J., STRAUCH K., RUSCHENDORF F., HEINZMANN A. et al. - A genome-wide screen on the genetics of atopy in a multiethnic European population reveals a major atopy locus on chromosome 3q21.3. Allergy, 2005, 60, 192-199.
    • (2005) Allergy , vol.60 , pp. 192-199
    • Kurz, T.1    Altmueller, J.2    Strauch, K.3    Ruschendorf, F.4    Heinzmann, A.5
  • 31
    • 0033753931 scopus 로고    scopus 로고
    • Major genes regulating total serum immunoglobulin E levels in families with asthma
    • XU J., POSTMA D.S., HOWARD T.D., KOPPELMAN G.H., ZHENG S.L. et al. - Major genes regulating total serum immunoglobulin E levels in families with asthma. Am. J. Hum. Genet., 2000, 67, 1163-1173.
    • (2000) Am. J. Hum. Genet. , vol.67 , pp. 1163-1173
    • Xu, J.1    Postma, D.S.2    Howard, T.D.3    Koppelman, G.H.4    Zheng, S.L.5
  • 32
    • 0035030767 scopus 로고    scopus 로고
    • A susceptibility locus for asthma-related traits on chromosome 7 revealed by genome-wide scan in a founder population
    • LAITINEN T., DALY M.J., RIOUX J.D., KAUPPI P., LAPRISE C. et al. - A susceptibility locus for asthma-related traits on chromosome 7 revealed by genome-wide scan in a founder population. Nat. Genet., 2001, 28, 87-91.
    • (2001) Nat. Genet. , vol.28 , pp. 87-91
    • Laitinen, T.1    Daly, M.J.2    Rioux, J.D.3    Kauppi, P.4    Laprise, C.5
  • 33
    • 19944409283 scopus 로고    scopus 로고
    • Clustering patterns of LOD scores for asthma-related phenotypes revealed by a genome-wide screen in 295 French EGEA families
    • BOUZIGON E., DIZIER M.H., KRÉHENBÜHL C., LEMAINQUE A., ANNESI-MAESANO I. et al. - Clustering patterns of LOD scores for asthma-related phenotypes revealed by a genome-wide screen in 295 French EGEA families. Hum. Mol. Genet., 2004, 13, 3103-3113.
    • (2004) Hum. Mol. Genet. , vol.13 , pp. 3103-3113
    • Bouzigon, E.1    Dizier, M.H.2    Kréhenbühl, C.3    Lemainque, A.4    Annesi-Maesano, I.5
  • 35
    • 16044372682 scopus 로고    scopus 로고
    • A genome-wide search for quantitative trait loci underlying asthma
    • DANIELS S.E., BHATTACHARRYA S., JAMES A., LEAVES N.I., YOUNG A. et al. - A genome-wide search for quantitative trait loci underlying asthma. Nature. 1996, 383, 247-250.
    • (1996) Nature , vol.383 , pp. 247-250
    • Daniels, S.E.1    Bhattacharrya, S.2    James, A.3    Leaves, N.I.4    Young, A.5
  • 36
    • 7344248546 scopus 로고    scopus 로고
    • Genome-wide search for asthma susceptibility loci in a founder population. The Collaborative Study on the Genetics of Asthma
    • OBER C., Cox N.J., ABNEY M., DI RIENZO A., LANDER E.S. et al. - Genome-wide search for asthma susceptibility loci in a founder population. The Collaborative Study on the Genetics of Asthma. Hum. Mol. Genet., 1998, 7, 1393-1398.
    • (1998) Hum. Mol. Genet. , vol.7 , pp. 1393-1398
    • Ober, C.1    Cox, N.J.2    Abney, M.3    Di Rienzo, A.4    Lander, E.S.5
  • 38
    • 7044226471 scopus 로고    scopus 로고
    • Positionally cloned susceptibility genes in allergy and asthma
    • KERE J., LAITINEN T. - Positionally cloned susceptibility genes in allergy and asthma. Curr. Opin. Immunol., 2004, 16, 689-694.
    • (2004) Curr. Opin. Immunol. , vol.16 , pp. 689-694
    • Kere, J.1    Laitinen, T.2
  • 40
    • 0037603549 scopus 로고    scopus 로고
    • Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma
    • ZHANG Y., LEAVES N.I., ANDERSON G.G., PONTING C.P., BROXHOLME J. et al. - Positional cloning of a quantitative trait locus on chromosome 13q14 that influences immunoglobulin E levels and asthma. Nat. Genet., 2003, 34, 181-186.
    • (2003) Nat. Genet. , vol.34 , pp. 181-186
    • Zhang, Y.1    Leaves, N.I.2    Anderson, G.G.3    Ponting, C.P.4    Broxholme, J.5
  • 41
    • 18444377877 scopus 로고    scopus 로고
    • Polymorphisms within the PHF11 gene at chromosome 13q14 are associated with childhood atopic dermatitis
    • JANG N., STEWART G., JONES G. - Polymorphisms within the PHF11 gene at chromosome 13q14 are associated with childhood atopic dermatitis. Genes Immun., 2005, 6, 262-264.
    • (2005) Genes Immun. , vol.6 , pp. 262-264
    • Jang, N.1    Stewart, G.2    Jones, G.3
  • 42
    • 0242329880 scopus 로고    scopus 로고
    • Positional cloning of a novel gene influencing asthma from chromosome 2q14
    • ALLEN M., HEINZMANN A., NOGUCHI E., ABECASIS G., BROXHOLME J. et al. - Positional cloning of a novel gene influencing asthma from chromosome 2q14. Nat. Genet., 2003, 35, 258-263.
    • (2003) Nat. Genet. , vol.35 , pp. 258-263
    • Allen, M.1    Heinzmann, A.2    Noguchi, E.3    Abecasis, G.4    Broxholme, J.5
  • 43
    • 11144357144 scopus 로고    scopus 로고
    • Characterization of a common susceptibility locus for asthma-related traits
    • LAITINEN T., POLVI A., RYDMAN P., VENDELIN J., PULKKINEN V. et al. - Characterization of a common susceptibility locus for asthma-related traits. Science. 2004, 304, 300-304.
    • (2004) Science , vol.304 , pp. 300-304
    • Laitinen, T.1    Polvi, A.2    Rydman, P.3    Vendelin, J.4    Pulkkinen, V.5
  • 44
  • 45
    • 20844448390 scopus 로고    scopus 로고
    • Haplotypes of G protein-coupled receptor 154 are associated with childhood allergy and asthma
    • MELEN E., BRUCE S., DOEKES G., KABESCH M., LAITINEN T. et al. - Haplotypes of G Protein-coupled Receptor 154 Are Associated with Childhood Allergy and Asthma. Am. J. Respir. Crit. Care Med., 2005, 171, 1089-1095.
    • (2005) Am. J. Respir. Crit. Care Med. , vol.171 , pp. 1089-1095
    • Melen, E.1    Bruce, S.2    Doekes, G.3    Kabesch, M.4    Laitinen, T.5
  • 46
    • 19944433619 scopus 로고    scopus 로고
    • Fine mapping and positional candidate studies identify HLA-G as an asthma susceptibility gene on chromosome 6p21
    • NICOLAE D., COX N.J., LESTER L.A., SCHNEIDER D., TAN Z. et al. - Fine mapping and positional candidate studies identify HLA-G as an asthma susceptibility gene on chromosome 6p21. Am. J. Hum. Genet., 2005, 76, 349-357.
    • (2005) Am. J. Hum. Genet. , vol.76 , pp. 349-357
    • Nicolae, D.1    Cox, N.J.2    Lester, L.A.3    Schneider, D.4    Tan, Z.5
  • 49
    • 20144388814 scopus 로고    scopus 로고
    • Gene-environment interaction effects on the development of immune responses in the 1st year of life
    • HOFFJAN S., NICOLAE D., OSTROVNAYA I., ROBERG K., EVANS M. et al. - Gene-environment interaction effects on the development of immune responses in the 1st year of life. Am. J. Hum. Genet., 2005, 76, 696-704.
    • (2005) Am. J. Hum. Genet. , vol.76 , pp. 696-704
    • Hoffjan, S.1    Nicolae, D.2    Ostrovnaya, I.3    Roberg, K.4    Evans, M.5
  • 50
    • 0042881041 scopus 로고    scopus 로고
    • Mathematical multi-locus approaches to localizing complex human trait genes
    • HOH J., OTT J. - Mathematical multi-locus approaches to localizing complex human trait genes. Nat. Rev. Genet., 2003, 4, 701-709.
    • (2003) Nat. Rev. Genet. , vol.4 , pp. 701-709
    • Hoh, J.1    Ott, J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.