Emergence of functional δ-opioid receptors induced by long-term treatment with morphine

Molecular Pharmacology

Volumn 69, Issue 4, 2006, Pages 1137-1145

  Ma, Junyi ^a   Zhang, Yong ^a   Kalyuzhny, Alex E ^b   Pan, Zhizhong Z ^a  

^a UNIVERSITY OF TEXAS   (United States)

^b UNIVERSITY OF MINNESOTA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID; DELTA OPIATE RECEPTOR; DELTA OPIATE RECEPTOR AGONIST; DELTORPHIN; DEXTRO PHENYLALANYLCYSTEINYLTYROSYL DEXTRO TRYPTOPHYLARGINYLTHREONYLPENICILLAMINYLTHREONINAMIDE 2,7 DISULFIDE; GLUTAMATE DECARBOXYLASE; MORPHINE; NALTRIBEN;

4 AMINOBUTYRIC ACID RELEASE; AMINO ACID SYNTHESIS; ANALGESIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN NERVE CELL; BRAIN STEM; CONTROLLED STUDY; DRUG ACTIVATION; IC 50; IMMUNOHISTOCHEMISTRY; MALE; MORPHINE TOLERANCE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RAPHE MAGNUS NUCLEUS; RAT; SPINAL PAIN; WESTERN BLOTTING;

ANIMALS; BASE SEQUENCE; DNA PRIMERS; IMMUNOHISTOCHEMISTRY; MICROINJECTIONS; MORPHINE; RATS; RECEPTORS, OPIOID, DELTA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 33645106458     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.105.019109     Document Type: Article

References (40)

1. Arvidsson U, Dado RJ, Riedl M, Lee JH, Law PY, Loh HH, Elde R, and Wessendorf MW (1995) delta-Opioid receptor immunoreactivity: distribution in brainstem and spinal cord, and relationship to biogenic amines and enkephalin. J Neurosci 15:1215-1235.
2. Bao L, Jin SX, Zhang C, Wang LH, Xu ZZ, Zhang FX, Wang LC, Ning FS, Cai HJ, Guan JS, et al. (2003) Activation of delta opioid receptors induces receptor insertion and neuropeptide secretion. Neuron 37:121-133.
3. Bie B, Peng Y, Zhang Y, and Pan ZZ (2005) cAMP-mediated mechanisms for pain sensitization during opioid withdrawal. J Neurosci 25:3824-3832.
4. Browning KN, Kalyuzhny AE, and Travagli RA (2004) Mu-opioid receptor trafficking on inhibitory synapses in the rat brainstem. J Neurosci 24:7344-7352.
5. Cahill CM, Morinville A, Lee MC, Vincent JP, Collier B, and Beaudet A (2001) Prolonged morphine treatment targets delta opioid receptors to neuronal plasma membranes and enhances delta-mediated antinociception. J Neurosci 21:7598-7607.
6. Cheng PY, Svingos AL, Wang H, Clarke CL, Jenab S, Beczkowska IW, Inturrisi CE, and Pickel VM (1995) Ultrastructural immunolabeling shows prominent presynaptic vesicular localization of delta-opioid receptor within both enkephalin- and nonenkephalin-containing axon terminals in the superficial layers of the rat cervical spinal cord. J Neurosci 15:5976-5988.
7. Chieng B and Christie MJ (1994) Inhibition by opioids acting on mu-receptors of GABAergic and glutamatergic postsynaptic potentials in single rat periaqueductal gray neurones in vitro. Br J Pharmacol 113:303-309.
8. Commons KG (2003) Translocation of presynaptic delta opioid receptors in the ventrolateral periaqueductal gray after swim stress. J Comp Neurol 464:197-207.
9. Commons KG, Beck SG, Rudoy C, and Van Bockstaele EJ (2001) Anatomical evidence for presynaptic modulation by the delta opioid receptor in the ventrolateral periaqueductal gray of the rat. J Comp Neurol 430:200-208.
10. Fields HL (2004) State-dependent opioid control of pain. Nat Rev Neurosci 5:565-575.
11. Glaum SR, Miller RJ, and Hammond DL (1994) Inhibitory actions of delta 1-, delta 2- and mu-opioid receptor agonists on excitatory transmission in lamina II neurons of adult rat spinal cord. J Neurosci 14:4965-4971.
12. Gomes I, Gupta A, Filipovska J, Szeto HH, Pintar JE, and Devi LA (2004) A role for heterodimerization of mu and delta opiate receptors in enhancing morphine analgesia. Proc Natl Acad Sci USA 101:5135-5139.
13. Guan J-S, Xu ZZ, Gao H, He SQ, Ma GQ, Sun T, Wang LH, Zhang ZN, Lena I, Kitchen I, et al. (2005) Interaction with vesicle luminal protachykinin regulates surface expression of δ-opioid receptors and opioid analgesia. Cell 122:619-631.
14. Hack SP, Bagley EE, Chieng BC, and Christie MJ (2005) Induction of delta-opioid receptor function in the midbrain after chronic morphine treatment. J Neurosci 25:3192-3198.
15. Hurley RW, Banfor P, and Hammond DL (2003) Spinal pharmacology of antinociception produced by microinjection of mu or delta opioid receptor agonists in the ventromedial medulla of the rat. Neuroscience 118:789-796.
16. Hurley RW and Hammond DL (2000) The analgesic effects of supraspinal mu and delta opioid receptor agonists are potentiated during persistent inflammation. J Neurosci 20:1249-1259.
17. Ingram SL, Vaughan CW, Bagley EE, Connor M, and Christie MJ (1998) Enhanced opioid efficacy in opioid dependence is caused by an altered signal transduction pathway. J Neurosci 18:10269-10276.
18. Inturrisi CE (2002) Clinical pharmacology of opioids for pain. Clin J Pain 18:S3-S13.
19. Kalyuzhny AE, Arvidsson U, Wu W, and Wessendorf MW (1996) mu-Opioid and delta-opioid receptors are expressed in brainstem antinociceptive circuits: studies using immunocytochemistry and retrograde tract-tracing. J Neurosci 16:6490-6503.
20. Kalyuzhny AE and Wessendorf MW (1998) Relationship of mu- and delta-opioid receptors to GABAergic neurons in the central nervous system, including antinociceptive brainstem circuits. J Comp Neurol 392:528-547.
21. Kieffer BL (2000) Opioid receptors: from genes to mice. J Pain 1:45-50.
22. Kohno T, Kumamoto E, Higashi H, Shimoji K, and Yoshimura M (1999) Actions of opioids on excitatory and inhibitory transmission in substantia gelatinosa of adult rat spinal cord. J Physiol 518 (Pt 3):803-813.
23. Kovelowski CJ, Bian D, Hruby VJ, Lai J, Ossipov MH, and Porreca F (1999) Selective opioid delta agonists elicit antinociceptive supraspinal/spinal synergy in the rat. Brain Res 843:12-17.
24. Krupnick JG and Benovic JL (1998) The role of receptor kinases and arrestins in G protein-coupled receptor regulation. Annu Rev Pharmacol Toxicol 38:289-319.
25. -ΔΔCT method. Methods 25:402-408.
26. Matthes HW, Maldonado R, Simonin F, Valverde O, Slowe S, Kitchen I, Befort K, Dierich A, Le Meur M, Dolle P, et al. (1996) Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the mu-opioid-receptor gene. Nature (Lond) 383:819-823.
27. Matthes HW, Smadja C, Valverde O, Vonesch JL, Foutz AS, Boudinot E, Denavit-Saubie M, Severini C, Negri L, Roques BP, et al. (1998) Activity of the delta-opioid receptor is partially reduced, whereas activity of the kappa-receptor is maintained in mice lacking the mu-receptor. J Neurosci 18:7285-7295.
28. Pan ZZ (2003) Opioid tolerance in adult and neonatal rats, in Opioid Research: Methods and Protocols (Pan ZZ ed), pp 223-232, Humana Press, Totowa, NJ.
29. Pan ZZ, Tershner SA, and Fields HL (1997) Cellular mechanism for anti-analgesic action of agonists of the kappa-opioid receptor. Nature (Lond) 389:382-385.
30. Pan ZZ, Williams JT, and Osborne PB (1990) Opioid actions on single nucleus raphe magnus neurons from rat and guinea-pig in vitro. J Physiol 427:519-532.
31. Paxinos G and Watson C (1986) The Rat Brain in Stereotaxic Coordinates, 2nd ed, Academic Press, Sydney.
32. Quinn B, Toga AW, Motamed S, and Merlic CA (1995) Fluoro nissl green: a novel fluorescent counterstain for neuroanatomy. Neurosci Lett 184:169-172.
33. Scherrer G, Befort K, Contet C, Becker J, Matifas A, and Kieffer BL (2004) The delta agonists DPDPE and deltorphin II recruit predominantly mu receptors to produce thermal analgesia: a parallel study of mu, delta and combinatorial opioid receptor knockout mice. Eur J Neurosci 19:2239-2248.
34. Schmidt BL, Tambeli CH, Levine JD, and Gear RW (2002) mu/delta Cooperativity and opposing kappa-opioid effects in nucleus accumbens-mediated antinociception in the rat. Eur J Neurosci 15:861-868.
35. Scholz J and Woolf CJ (2002) Can we conquer pain? Nat Neurosci 5 (Suppl):1062-1067.
36. Sora I, Takahashi N, Funada M, Ujike H, Revay RS, Donovan DM, Miner LL, and Uhl GR (1997) Opiate receptor knockout mice define mu receptor roles in endogenous nociceptive responses and morphine-induced analgesia. Proc Natl Acad Sci USA 94:1544-1549.
37. Standifer KM, Chien CC, Wahlestedt C, Brown GP, and Pasternak GW (1994) Selective loss of delta opioid analgesia and binding by antisense oligodeoxynucleotides to a delta opioid receptor. Neuron 12:805-810.
38. Tan CM, Brady AE, Nickols HH, Wang Q, and Limbird LE (2004) Membrane trafficking of G protein-coupled receptors. Annu Rev Pharmacol Toxicol 44:559-609.
39. Wang H and Wessendorf MW (2002) Mu- and delta-opioid receptor mRNAs are expressed in periaqueductal gray neurons projecting to the rostral ventromedial medulla. Neuroscience 109:619-634.
40. Zhu Y, King MA, Schuller AG, Nitsche JF, Reidl M, Elde RP, Unterwald E, Pasternak GW, and Pintar JE (1999) Retention of supraspinal delta-like analgesia and loss of morphine tolerance in delta opioid receptor knockout mice. Neuron 24:243-252.