Residues of dimethoate in the liver and AChE activity in blood of rats after exposure to dimethoate, and dimethoate and pyrantel embonate

Polish Journal of Veterinary Sciences

Volumn 9, Issue 1, 2006, Pages 43-49

  Barski, D ^a   Zasadowski, A ^a  

^a UNIVERSITY OF WARMIA AND MAZURY IN OLSZTYN   (Poland)

Author keywords

Acetylcholinesterase (AChE); Dimethoate; Pyrantel embonate; Rat; Residues

Indexed keywords

ACETYLCHOLINESTERASE; CHOLINESTERASE INHIBITOR; DIMETHOATE; DRUG RESIDUE; INSECTICIDE; PYRANTEL EMBONATE;

ANIMAL; ARTICLE; BIOASSAY; BLOOD; CHEMISTRY; DOSE RESPONSE; DRUG COMBINATION; DRUG POTENTIATION; LD 50; LIVER; MALE; METABOLISM; RANDOMIZATION; RAT; TIME; WISTAR RAT;

ACETYLCHOLINESTERASE; ANIMALS; BIOLOGICAL ASSAY; CHOLINESTERASE INHIBITORS; DIMETHOATE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMBINATIONS; DRUG RESIDUES; DRUG SYNERGISM; INSECTICIDES; LETHAL DOSE 50; LIVER; MALE; PYRANTEL PAMOATE; RANDOM ALLOCATION; RATS; RATS, WISTAR; TIME FACTORS;

ANIMALIA;

EID: 33645105125     PISSN: 15051773     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. Abou-Donia MB (2003) Organophosphorus ester-induced chronic neurotoxicity. Arch Environ Health 58: 484-497.
2. Abu-Qare AW, Abou-Donia MB (2001) Inhibition and recovery of maternal and fetal cholinesterase enzyme activity following a single cutaneous dose of methyl parathion and diazinon, alone and in combination, in pregnant rats. J Appl Toxicol 21: 307-316.
3. Afifi NA, Ramadan A, el-Aziz MI, Saki EE (1991) Influence of dimethoate on testicular and epididymal organs, testosterone plasma level and their tissue residues in rats. Dtsch Tierarztl Wocheschr 98: 419-423.
4. Aprea C, Terenzoni B, Angelis VDe, Sciarra G, Lunghini L, Borzacchi G, Vasconi D, Fani D, Quercia A, Salvan A, Settimi L (2004) Evaluation of Skin and Respiratory Doses and urinary Excretion of Alkylphosphates in Workers Exposed to Dimethoate During Treatment of Olive Trees. Arch Environ Contam Toxicol 48: 127-134.
5. Aysal P, Tiryaki O, Tuncbilek AS (2004) 14C-Dimethoate Residues in Tomatoes and Tomato Products. Bull Environ Contam Toxicol 73: 351-357.
6. Bapiro TE, Egnell AC, Hasler JA, Masimirembwa CM (2001) Application of higher throughput screening (HTS) inhibition assays to evaluate the interaction of antiparasitic drugs with cytochrome P450s. Drug Metab Dispos 29: 30-35.
7. Baranowa NP, Aleksandrova LG, Kovalenko VF (1986) Tissue distribution and biochemical effects of dimethoate entering the body via the skin. Gig Tr Prof Zabol 3: 20-23.
8. Barski D, Zasadowski A (1997) The effects of toxic activity of lead and selected phosphoorganic insecticides in rats. II. Acetylcholinesterase activity (AChE) assessment in the blood and brain of rats intoxicated with lead, fenitrothion and foschlor as well as with combinations of lead with fenitrothion and foschlor. Acta Acad Agricult Tech Olst Veterinaria 25: 101-111.
9. Churchill D, Churchill DJ, Will RG (1999) Organophosphate exposure and variant Creutzfeldt-Jakob disease. Lancet 353: 1410.
10. Deike S, Wosnitzka H (1989) Behavior of serum cholinesterase and acetylcholinesterase activity in acute dimethoate poisoning. Z Gesamte Inn Med 44: 548-549.
11. Dongren Y, Tao L, Fengsheng H (1999) Electroneurophysiological studies in rats of acute dimethoate poisoning. Toxicol Lett 107: 249-254.
12. Getenga ZM, Jondiko JIO, Wandiga SO, Beck E (2000) Dissipation Behavior of Malathion and Dimethoate Residues from the Soil and Their Uptake by Garden Pea (Pisum sativum). Bull Environ Contam Toxicol 64: 359-367.
13. Gokbulut C, Nolan AM, Mckellar OA (2001) Pharmacokinetic disposition and faecal excretion of pyrantel embonate following oral administration in horses. J Vet Pharmacol Ther 24: 77-79.
14. Horton J (2003) Global anthelmintic chemotherapy programs: learning from history. Trends in Pathol 19: 405-409.
15. Karanth S, Olivier K, Liu J, Pope C (2001) In vivo interaction between chlorpyrifos and parathion in adult rats: sequence of administration can markedly influence toxic outcome. Toxicol Appl Pharmacol 177: 247-255.
16. Mileson BE, Chambers JE, Chen WL, Dettbarn W (1998) Common mechanism of toxicity: a case study of organophosphorus pesticides. Toxicol Sci 41: 8-20.
17. Ruckebusch Y, Ruckebusch M (1961) Sur le systeme acetylcholinesterase et la pharmacologie des insecticides organophosphores. Cah Med Vet 30: 126-151.
18. Sharma Y, Bashir S., Irshad M, Gupta SD, Dogra TD (2005) Effects of acute dimethoate administration on antioxidant status of liver and brain of experimental rats. Toxicology 206: 49-57.
19. Siller FR, Quintanilla-Vega B, Cebrian ME, Albores A (1997) Effects of arsenite pretreatment on the acute toxicity of parathion. Toxicology 116: 59-65.
20. Soliman KM (2001) Changes in concentration of pesticide residues in potatoes during washing and home preparation. Food Chem Toxicol 39: 887-891.
21. Storm JE, Rozman KK, Doull J (2000) Occupational exposure limits for 30 organophosphate pesticides based on inhibition of red blood cell acetylcholinesterase. Toxicology 150: 1-29.
22. Vale JA (1998) Toxicokinetic and toxicodynamic aspects of organophosphorus (OP) insecticide poisoning. Toxicol Lett 102-103: 649-652.
23. WHO (1996) Report of the WHO Informal Consultation on hookworm infection and anaemia in girls and women. Division of Control of Tropical Diseases, WHO/CTD/SIP.96.1. Geneva, pp 25-32.
24. Zasadowski A, Barski D (1999) The effects of cadmium chloride and fenitrothion administration on the activity of acetylcholine esterase (AChE) and fenitrothion residues in broiler chicken. Bromat Chem Toxicol 32: 143-148.
25. Zasadowski A, Barski D, Spodniewska A (1997) The effect of lead and selenium on the residue levels of phosphoro-organic insecticides in rat tissues. Acta Pol Toxicol 5: 63-71.