Detection of the Mr 110,000 lung resistance-related protein LRP/MVP with monoclonal antibodies

Journal of Histochemistry and Cytochemistry

Volumn 49, Issue 11, 2001, Pages 1379-1385

  Schroeijers, A B ^a   Scheffer, G L ^a   Reurs, A W ^a   Pijnenborg, A C L M ^a   Abbondanza, C ^a   Wiemer, E A C ^a   Scheper, R J ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

Author keywords

Lung resistance related protein (LRP); Major vault protein (MVP); Monoclonal antibody (MAb); Multidrug resistance (MDR); Vault

Indexed keywords

DOXORUBICIN; LUNG RESISTANCE PROTEIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY MVP 16; MONOCLONAL ANTIBODY MVP 18; MONOCLONAL ANTIBODY MVP 37; MONOCLONAL ANTIBODY MVP 9; RIBONUCLEOPROTEIN; UNCLASSIFIED DRUG; FIXATIVE; FORMALDEHYDE; PARAFFIN; TUMOR PROTEIN;

ANIMAL CELL; ARTICLE; CHEMOTHERAPY; CONTROLLED STUDY; DIAGNOSTIC VALUE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; LUNG RESISTANCE; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; PREDICTION; PRIORITY JOURNAL; PROGNOSIS; PROTEIN EXPRESSION; SENSITIVITY AND SPECIFICITY; ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; CELL CULTURE; DRUG RESISTANCE; IMMUNOLOGY; LUNG NON SMALL CELL CANCER; LUNG TUMOR; MALE; METABOLISM; SMALL CELL CARCINOMA; TISSUE FIXATION; WESTERN BLOTTING;

ANIMALS; ANTIBODIES, MONOCLONAL; BLOTTING, WESTERN; CARCINOMA, NON-SMALL-CELL LUNG; CARCINOMA, SMALL CELL; DRUG RESISTANCE, MULTIPLE; DRUG RESISTANCE, NEOPLASM; FIXATIVES; FORMALDEHYDE; IMMUNOHISTOCHEMISTRY; LUNG NEOPLASMS; MALE; MICE; MICE, INBRED BALB C; NEOPLASM PROTEINS; PARAFFIN EMBEDDING; TISSUE FIXATION; TUMOR CELLS, CULTURED; VAULT RIBONUCLEOPROTEIN PARTICLES;

EID: 0034740685     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1177/002215540104901106     Document Type: Article

References (26)

1. Interaction of vault particles with estrogen receptor in the MCF-7 breast cancer cell
2. The multidrug resistance protein family
3. Evidence that vault ribonucleoprotein particles localize to the nuclear pore complex
4. A multidrug resistance transporter from human MCF-7 breast cancer cells [erratum Proc Natl Acad Sci USA 1999;96(5):2569]
5. Identification of novel drug resistance-associated proteins by a panel of rat monoclonal antibodies
6. P-glycoproteina mediator of multidrug resistance in tumour cells
7. Characterization of the sea urchin major vault proteina possible role for vault ribonucleoprotein particles in nucleocytoplasmic transport
8. Recombinant major vault protein is targeted to neuritic tips of PC12 cells
9. The major vault protein (MVP100) is contained in cholinergic nerve terminals of electric ray electric organ
10. Broad distribution of the multidrug resistance-related vault lung resistance protein in normal human tissues and tumors
11. Vault-related resistance to anticancer drugs determined by the expression of the major vault protein LRP
12. Overlapping phenotypes of multidrug resistance among panels of human cancer-cell lines
13. Vaults. II. Ribonucleoprotein structures are highly conserved among higher and lower eukaryotes
14. Isolation and characterization of a novel ribonucleoprotein particle: Large structures contain a single species of small RNA
15. Vaults are up-regulated in multidrug-resistant cancer cell lines
16. Multidrug resistance and the lung resistance-related protein in human colon carcinoma SW-620 cells
17. Structure of the vault, a ubiquitous cellular component
18. Drug transport variants without P-glycoprotein overexpression from a human squamous lung cancer cell line after selection with doxorubicin
19. Clinical multidrug resistance in cancer: A multi-factorial problem
20. A method for exposing hidden antigenic sites in paraformaldehyde-fixed cultured cells, applied to initially unreactive antibodies
21. Unlocking vaults: Organelles in search of a function
22. The drug resistance-related protein LRP is the human major vault protein
23. Overexpression of a M(r) 110,000 vesicular protein in non-P-glycoprotein-mediated multidrug resistance
24. Upregulation of vaults, Pgp and MRP1 during dendritic cell development: A physiological role for vaults in dendritic cell differentiation
25. The Mr 193,000 vault protein is up-regulated in multidrug-resistant cancer cell lines
26. Multifactorial drug resistance in an adriamycin-resistant human small cell lung carcinoma cell line