Intrauterine proximity to male fetuses affects the morphology of the sexually dimorphic nucleus of the preoptic area in the adult rat brain

European Journal of Neuroscience

Volumn 23, Issue 5, 2006, Pages 1234-1240

  Pei, Minjuan ^a   Matsuda, Ken Ichi ^a   Sakamoto, Hirotaka ^a   Kawata, Mitsuhiro ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

Aromatase; Calbindin; Estradiol; Sex differentiation; Testosterone

Indexed keywords

BIOCHEMICAL MARKER; CALBINDIN; ESTRADIOL; STEROID HORMONE; TESTOSTERONE;

ADULTHOOD; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN DEVELOPMENT; BRAIN LEVEL; BRAIN NUCLEUS; BRAIN SIZE; CELL STRUCTURE; CONTROLLED STUDY; FEMALE; FETUS; FETUS DEVELOPMENT; IMMUNOREACTIVITY; MALE; NONHUMAN; PREGNANCY; PRENATAL DEVELOPMENT; PRENATAL DRUG EXPOSURE; PREOPTIC AREA; PRIORITY JOURNAL; RAT; SEX DIFFERENCE;

ANIMALS; ESTRADIOL; FEMALE; FETUS; HUMANS; MALE; PREGNANCY; PREGNANCY, ANIMAL; PREOPTIC AREA; RATS; SEX CHARACTERISTICS; SEX DIFFERENTIATION; TESTOSTERONE;

EID: 33645091224     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2006.04661.x     Document Type: Article

References (50)

1. Anderson RH. Fleming DE. Rhees RW. Kinghorn E. 1986 Relationships between sexual activity, plasma testosterone, and the volume of the sexually dimorphic nucleus of the preoptic area in prenatally stressed and non-stressed rats Brain Res 370 1 10
2. Bloch GJ. Gorski RA. 1988 Cytoarchitectonic analysis of the SDN-POA of the intact and gonadectomized rat JCompNeurol 275 604 612
3. Carretero J. Vazquez G. Blanco E. Rubio M. Santos M. Martin-Clavijo A. Torres JL. Vazquez R. 1999 Immunohistochemical evidence of the presence of aromatase P450 in the rat hypophysis Cell Tissue Res 295 419 423
4. Davis EC. Popper P. Gorski RA. 1996 The role of apoptosis in sexual differentiation of the rat sexually dimorphic nucleus of the preoptic area Brain Res 734 10 18
5. De Jonge FH. Louwerse AL. Ooms MP. Evers P. Endert E. van de Poll NE. 1989 Lesions of the SDN-POA inhibit sexual behavior of male wistar rats Brain ResBull 23 483 492
6. De Vries GJ. Simerly RB. 2002 Anatomy, development, and function of sexually dimorphic neural circuits in the mammalian brain. In Pfaff DW. Arnold AP. Etgen AM. Fahrbach SE. Rubin RT. (Eds) Hormones, Brain and Behavior Vol. 4 Academic Press
7. Dodson RE. Gorski RA. 1993 Testosterone propionate administration prevents the loss of neurons within the central part of the medial preoptic nucleus JNeurobiol 24 80 88
8. Dodson RE. Shryne JE. Gorski RA. 1988 Hormonal modification of the number of total and late-arising neurons in the central part of the medial preoptic nucleus of the rat JCompNeurol 275 623 629
9. Dohler KD. Coquelin A. Davis F. Hines M. Shryne JE. Gorski RA. 1984 Pre- and postnatal influence of testosterone propionate and diethylstilbestrol on differentiation of the sexually dimorphic nucleus of the preoptic area in male and female rats Brain Res 302 291 295
10. Even MD. Dhar MG. vom Saal FS. 1992 Transport of steroids between fetuses via amniotic fluid in relation to the intrauterine position phenomenon in rats JReprodFertil 96 709 716
11. Faber KA. Hughes CL. Jr. 1993 Dose-response characteristics of neonatal exposure to genistein on pituitary responsiveness to gonadotropin releasing hormone and volume of the sexually dimorphic nucleus of the preoptic area (SDN-POA) in postpubertal castrated female rats ReprodToxicol 7 35 39
12. Faber KA. Ayyash L. Dixon S. Hughes CL. Jr. 1993 Effect of neonatal diethylstilbestrol exposure on volume of the sexually dimorphic nucleus of the preoptic area of the hypothalamus and pituitary responsiveness to gonadotropin-releasing hormone in female rats of known anogenital distance at birth BiolReprod 48 947 951
13. Forger NG. Galef BG. Jr. Clark MM. 1996 Intrauterine position affects motoneuron number and muscle size in a sexually dimorphic neuromuscular system Brain Res 735 119 124
14. Gorski RA. Gordon JH. Shryne JE. Southam AM. 1978 Evidence for a morphological sex difference within the medial preoptic area of the rat brain Brain Res 148 333 346
15. Gorski RA. Harlan RE. Jacobson CD. Shryne JE. Southam AM. 1980 Evidence for the existence of a sexually dimorphic nucleus in the preoptic area of the rat JCompNeurol 193 529 539
16. Hernandez-Tristan R. Arevalo C. Canals S. 1999 Effect of prenatal uterine position on male and female rats sexual behavior PhysiolBehav 67 401 408
17. Hines M. Davis FC. Coquelin A. Goy RW. Gorski RA. 1985 Sexually dimorphic regions in the medial preoptic area and the bed nucleus of the stria terminalis of the guinea pig brain: a description and an investigation of their relationship to gonadal steroids in adulthood JNeurosci 5 40 47
18. Houtsmuller EJ. Slob AK. 1990 Masculinization and defeminization of female rats by males located caudally in the uterus PhysiolBehav 48 555 560
19. Houtsmuller EJ. Brand T. de Jonge FH. Joosten RN. van de Poll NE. Slob AK. 1994 SDN-POA volume, sexual behavior, and partner preference of male rats affected by perinatal treatment with ATD PhysiolBehav 56 535 541
20. Hsieh YL. Hsu C. Yang SL. Hsu HK. Peng MT. 1996 Estradiol modulation of neuron loss in the medial division of medial preoptic nucleus in rats during aging Gerontology 42 18 24
21. Ikeda M. Mitsui T. Setani K. Tamura M. Kakeyama M. Sone H. Tohyama C. Tomita T. 2005 In utero and lactational exposure to 2,3,7,8-tetrachlorodibenzo- p-dioxin in rats disrupts brain sexual differentiation ToxicolApplPharmacol 205 98 105
22. Ito S. Murakami S. Yamanouchi K. Arai Y. 1986 Prenatal androgen exposure, preoptic area and reproductive functions in the female rat Brain Dev 8 463 468
23. Jones D. Gonzalez-Lima F. Crews D. Galef BG. Jr. Clark MM. 1997 Effects of intrauterine position on the metabolic capacity of the hypothalamus of female gerbils PhysiolBehav 61 513 519
24. Kawata M. 1995 Roles of steroid hormones and their receptors in structural organization in the nervous system NeurosciRes 24 1 46
25. Lauber ME. Sarasin A. Lichtensteiger W. 1997a Transient sex differences of aromatase (CYP19) mRNA expression in the developing rat brain Neuroendocrinology 66 173 180
26. Lauber ME. Sarasin A. Lichtensteiger W. 1997b Sex differences and androgen-dependent regulation of aromatase (CYP19) mRNA expression in the developing and adult rat brain JSteroid BiochemMolBiol 61 359 364
27. Lephart ED. Simpson ER. McPhaul MJ. Kilgore MW. Wilson JD. Ojeda SR. 1992 Brain aromatase cytochrome P-450 messenger RNA levels and enzyme activity during prenatal and perinatal development in the rat Brain ResMolBrain Res 16 187 192
28. Lephart ED. Call SB. Rhees RW. Jacobson NA. Weber KS. Bledsoe J. Teuscher C. 2001 Neuroendocrine regulation of sexually dimorphic brain structure and associated sexual behavior in male rats is genetically controlled BiolReprod 64 571 578
29. Lund TD. Salyer DL. Fleming DE. Lephart ED. 2000 Pre- or postnatal testosterone and flutamide effects on sexually dimorphic nuclei of the rat hypothalamus Brain ResDevBrain Res 120 261 266
30. Madeira MD. Leal S. Paula-Barbosa MM. 1999 Stereological evaluation and Golgi study of the sexual dimorphisms in the volume, cell numbers, and cell size in the medial preoptic nucleus of the rat JNeurocytol 28 131 148
31. McCarthy MM. Besmer HR. Jasobs SC. Keidan GMO. Gibbs RB. 1997 Influence of maternal grooming, sex and age on FOS immunoreactivity in the preoptic area of the neonatal rats: implications for sexual differentiation DevNeurosci 19 488 496
32. Meisel RL. Ward IL. 1981 Fetal female rats are masculinized by male littermates located caudally in the uterus Science 213 239 242
33. Palanza P. Parmigiani S. vom Saal FS. 1995 Urine marking and maternal aggression of wild female mice in relation to anogenital distance at birth PhysiolBehav 58 827 835
34. Rhees RW. Shryne JE. Gorski RA. 1990a Onset of the hormone-sensitive perinatal period for sexual differentiation of the sexually dimorphic nucleus of the preoptic area in female rats JNeurobiol 21 781 786
35. Rhees RW. Shryne JE. Gorski RA. 1990b Termination of the hormone-sensitive period for differentiation of the sexually dimorphic nucleus of the preoptic area in male and female rats Brain ResDevBrain Res 52 17 23
36. Rhees RW. Al-Saleh HN. Kinghorn EW. Fleming DE. Lephart ED. 1999 Relationship between sexual behavior and sexually dimorphic structures in the anterior hypothalamus in control and prenatally stressed male rats Brain ResBull 50 193 199
37. Rhoda J. Corbier P. Roffi J. 1984 Gonadal steroid concentrations in serum and hypothalamus of the rat at birth: aromatization of testosterone to 17 beta-estradiol Endocrinology 114 1754 1760
38. Richmond G. Sachs BD. 1984 Further evidence for masculinization of female rats by males located caudally in utero HormBehav 18 484 490
39. Ryan BC. Vandenbergh JG. 2002 Intrauterine position effects NeurosciBiobehavRev 26 665 678
40. vom Saal FS. 1989 Sexual differentiation in litter-bearing mammals: influence of sex of adjacent fetuses in utero JAnimSci 67 1824 1840
41. vom Saal FS. Bronson FH. 1980 Sexual characteristics of adult female mice are correlated with their blood testosterone levels during prenatal development Science 208 597 599
42. vom Saal FS. Grant WM. McMullen CW. Laves KS. 1983 High fetal estrogen concentrations: correlation with increased adult sexual activity and decreased aggression in male mice Science 220 1306 1309
43. Sakamoto H. Mezaki Y. Shikimi H. Ukena K. Tsutsui K. 2003 Dendritic growth and spine formation in response to estrogen in the developing Purkinje cell Endocrinology 144 4466 4477
44. Sickel MJ. McCarthy MM. 2000 Calbindin-D28k immunoreactivity is a marker for a subdivision of the sexually dimorphic nucleus of the preoptic area of the rat: developmental profile and gonadal steroid modulation JNeuroendocrinol 12 397 402
45. Simerly RB. Swanson LW. Gorski RA. 1984 Demonstration of a sexual dimorphism in the distribution of serotonin-immunoreactive fibers in the medial preoptic nucleus of the rat JCompNeurol 225 151 166
46. Tarttelin MF. Gorski RA. 1988 Postnatal influence of diethylstilbestrol on the differentiation of the sexually dimorphic nucleus in the rat is as effective as perinatal treatment Brain Res. 456 271 274
47. Tobet SA. Hanna IK. 1997 Ontogeny of sex differences in the mammalian hypothalamus and preoptic area CellMolNeurobiol 17 565 601
48. Turkenburg JL. Swaab DF. Endert E. Louwerse AL. van de Poll NE. 1988 Effects of lesions of the sexually dimorphic nucleus on sexual behavior of testosterone-treated female Wistar rats Brain ResBull 21 215 224
49. Weisz J. Ward IL. 1980 Plasma testosterone and progesterone titers of pregnant rats, their male and female fetuses, and neonatal offspring Endocrinology 106 306 316
50. Yahr P. Finn PD. Hoffman NW. Sayag N. 1994 Sexually dimorphic cell groups in the medial preoptic area that are essential for male sex behavior and the neural pathways needed for their effects Psychoneuroendocrinology 19 463 470