Stereological evaluation and Golgi study of the sexual dimorphisms in the volume, cell numbers, and cell size in the medial preoptic nucleus of the rat

Journal of Neurocytology

Volumn 28, Issue 2, 1999, Pages 131-148

  Madeira, Maria Dulce ^a   Leal, S ^a   Paula Barbosa, M M ^a  

^a Porto School of Nursing   (Portugal)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; CELL COUNT; CELL DENSITY; CELL DIFFERENTIATION; CELL DIVISION; CELL SIZE; DENDRITIC CELL; GOLGI COMPLEX; MEDIAL PREOPTIC AREA; NERVE CELL; NEUROPIL; NONHUMAN; PRIORITY JOURNAL; RAT; RECEPTOR DENSITY; SEX DIFFERENCE; STEREOLOGY;

ANIMALS; AZURE STAINS; BODY WEIGHT; BRAIN; CELL COUNT; CELL SIZE; DENDRITES; FEMALE; GOLGI APPARATUS; MALE; NEURONS; NEUROPIL; ORGAN SIZE; PREOPTIC AREA; RATS; RATS, WISTAR; SEX CHARACTERISTICS; SEX FACTORS;

ANIMALIA;

EID: 0033389459     PISSN: 03004864     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1007076206828     Document Type: Article

References (76)

1. ANDERSON, R. H., FLEMING, D. E., RHEES, R. W. & KINGHORN, E. (1986) Relationships between sexual activity, plasma testosterone, and the volume of the sexually dimorphic nucleus of the preoptic area in prenatally stressed and non-stressed rats. Brain Research 370, 1-10.
2. ANDRADE, J. P., CASTANHEIRA-VALE, A. J., PAZ-DIAS, P. G., MADEIRA, M. D. & PAULA-BARBOSA, M. M. (1996) The dendritic trees of neurons from the hippocampal formation of protein-deprived adult rats. A quantitative Golgi study. Experimental Brain Research 109, 419-33.
3. AYOUB, D. M., GREENOUGH, W. T. & JURASKA, J. M. (1983) Sex differences in dendritic structure in the preoptic area of the Juvenile Macaque monkey brain. Science 219, 197-98.
4. BAYER, S. A. & ALTMAN, J. (1987) Development of the preoptic area: Time and site of origin, migratory routes, and settling patterns of its neurons. Journal of Comparative Neurology 265, 65-95.
5. BLEIER, R., BYNE, W. & SIGGELKOW, I. (1982) Cytoarchitectonic sexual dimorphisms of the medial preoptic and anterior hypothalamic areas in guinea-pig, rat, hamster, and mouse. Journal of Comparative Neurology 212, 118-30.
6. BLOCH, G. J. & GORSKI, R. A. (1988a) Cytoarchitectonic analysis of the SDN-POA of the intact and gonadectomized rat. Journal of Comparative Neurology 275, 604-12.
7. BLOCH, G. J. & GORSKI, R. A. (1988b) Estrogen/progesterone treatment in adulthood affects the size of several components of the medial preoptic area in the male rat. Journal of Comparative Neurology 275, 613-22.
8. BLOCH, G. J., KURTH, S. M., AKESSON, T. R. & MICEVYCH, P. E. (1992) Estrogen-concentrating cells within cell groups of the medial preoptic area: Sex differences and co-localization with galanin-immunoreactive cells. Brain Research 595, 301-08.
9. BYNE, W. & BLEIER, R. (1987) Medial preoptic sexual dimorphisms in the guinea-pig. I. An investigation of their hormonal dependence. Journal of Neuroscience 7, 2688-96.
10. CAVALIERI, B. (1966) Geometria degli Indivisibili. Torino: Unione Tipografico Editrice.
11. CHERRY, J. A., BASHAM, M. E., WEAVER, C. E., KROHMER, R. W. & BAUM, M. J. (1990) Ontogeny of the sexually dimorphic male nucleus in the preoptic / anterior hypothalamus of ferrets and its manipulation by gonadal steroids. Journal of Neurobiology 21, 844-57.
12. COLEMAN, P. D. & REISEN, A. H. (1968) Environmental effects on cortical dendritic fields. I. Rearing in the dark. Journal of Anatomy 102, 363-74.
13. COMMINS, D. & YAHR, P. (1984) Adult testosterone levels influence the morphology of a sexually dimorphic area in the Mongolian gerbil brain. Journal of Comparative Neurology 224, 132-40.
14. nd Edition, pp. 213-343. New York: John Wiley & Sons.
15. CRUZ-ORIVE, L. M. (1997) Stereology of single objects. Journal of Microscopy 186, 93-107.
16. CRUZ-ORIVE, L. M. & WEIBEL, E. R. (1990) Recent stereological methods for cell biology: A brief survey. American Journal of Physiology 258, 148-56.
17. DAVIS, E. C., POPPER, P. & GORSKI, R. A. (1996) The role of apoptosis in sexual differentiation of the rat sexually dimorphic nucleus of the preoptic area. Brain Research 734, 10-18.
18. DE RUITER, J. P. & UYLINGS, H. B. M. (1987) Morphometric and dendritic analysis of fascia dentata granule cells in human aging and senile dementia. Brain Research 402, 217-29.
19. DIAMOND, M. C. (1985) Rat forebrain morphology: Right-left; male-female; young-old; enriched-impoverished. In Cerebral Lateralization in Nonhuman Species (edited by Glick, S. D.) pp. 73-88. New York: Academic Press.
20. DODSON, R. E. & GORSKI, R. A. (1993) Testosterone propionate administration prevents the loss of neurons within the central part of the medial preoptic nucleus of the rat. Journal of Neurobiology 24, 80-88.
21. DODSON, R. E., SHRYNE, J. E. & GORSKI, R. A. (1988) Hormonal modification of the number of total and late-arising neurons in the central part of the medial preoptic nucleus of the rat. Journal of Comparative Neurology 275, 623-29.
22. DÖHLER, K.-D., COQUELIN, A., DAVIS, F., HINES, M., SHRYNE, J. E. & GORSKI, R. A. (1984a) Pre- and postnatal influence of testosterone propionate and diethylstilbestrol on differentiation of the sexually dimorphic nucleus of the preoptic area in male and female rats. Brain Research 302, 291-95.
23. DÖHLER, K. D., SRIVASTAVA, S. S., SHRYNE, J. E., JARZAB, B., SIPOS, A. & GORSKI, R. A. (1984b) Differentiation of the sexually dimorphic nucleus in the preoptic area of the rat brain is inhibited by postnatal treatment with an estrogen antagonist. Neuroendocrinology 38, 297-301.
24. EAYRS, T. J. (1955) The cerebral cortex of normal and hypothyroid rats. Acta Anatomica 25, 160-83.
25. ECKENHOFF, M. F. & RAKIC, P. (1984) Radial organization of the hippocampal dentate gyrus: a Golgi, ultrastructural, and immunocytochemical analysis in the developing Rhesus monkey. Journal of Comparative Neurology 233, 1-21.
26. GORSKI, R. A., GORDON, J. H., SHRYNE, J. E. & SOUTHAM, A. M. (1978) Evidence for a morphological sex difference within the medial preoptic area of the rat brain. Brain Research 148, 333-46.
27. GORSKI, R. A., HARLAN, R. E., JACOBSON, C. D., SHRYNE, J. E. & SOUTHAM, A. M. (1980) Evidence for the existence of a sexually dimorphic nucleus in the preoptic area of the rat. Journal of Comparative Neurology 193, 529-39.
28. GREENOUGH, W. T., CARTER, C. S., STEERMAN, C. & DEVOOGD, T. J. (1977) Sex differences in dendritic patterns in hamster preoptic area. Brain Research 126, 63-72.
29. GUNDERSEN, H. J. G. & JENSEN, E. B. (1987) The efficiency of systematic sampling in stereology and its prediction. Journal of Microscopy 147, 229-63.
30. GUNDERSEN, H. J. G., BENDTSEN, T. F., KORBO, L., MARCUSSEN, N., MØLLER, A., NIELSEN, K., NYENGAARD, J. R., PAKKENBERG, B., SØRENSEN, F. B., VESTERBY, A. & WEST, M. J. (1988) Some new, simple and efficient stereological methods and their use in pathological research and diagnosis. Acta Pathologica et Microbiologica Scandinavica 96, 379-94.
31. HAMMER, R. P. & JACOBSON, C. D. (1984) Sex difference in dendritic development of the sexually dimorphic nucleus of the preoptic area in the rat. International Journal of Developmental Neuroscience 2, 77-85.
32. HINES, M., DAVIS, F. C., COQUELIN, A., GOY, R. W. & GORSKI, R. A. (1985) Sexually dimorphic regions in the medial preoptic area and the bed nucleus of the stria terminalis of the guinea pig brain: A description and an investigation of their relationship to gonadal steroids in adulthood. Journal of Neuroscience 5, 40-47.
33. HOFFMAN, N. W., KIM, Y. I., GORSKI, R. A. & DUDEK, F. E. (1994) Homogeneity of intracellular electrophysiological properties in different neuronal subtypes in medial preoptic slices containing the sexually dimorphic nucleus of the rat. Journal of Comparative Neurology 345, 396-408.
34. HORNER, C. H. (1993) Plasticity of the dendritic spine. Progress in Neurobiology 41, 281-321.
35. JACOBSON, C. D. & GORSKI, R. A. (1981) Neurogenesis of the sexually dimorphic nucleus of the preoptic area in the rat. Journal of Comparative Neurology 196, 519-29.
36. JACOBSON, C. D., SHRYNE, J. E., SHAPIRO, F. & GORSKI, R. A. (1980) Ontogeny of the sexually dimorphic nucleus of the preoptic area. Journal of Comparative Neurology 193, 541-48.
37. JACOBSON, C. D., CSERNUS, V. J., SHRYNE, J. E. & GORSKI, R. A. (1981) The influence of gonadectomy, androgen exposure, or a gonadal graft in the neonatal rat on the volume of the sexually dimorphic nucleus of the preoptic area. Journal of Neuroscience 1, 1142-47.
38. JACOBSON, C. D., DAVIS, F. C. & GORSKI, R. A. (1985) Formation of the sexually dimorphic nucleus of the preoptic area: Neuronal growth, migration and changes in cell number. Developmental Brain Research 21, 7-18.
39. JACOBSON, C. D., ARNOLD, A. P. & GORSKI, R. A. (1987) Steroid autoradiography of the sexually dimorphic nucleus of the preoptic area. Brain Research 414, 349-56.
40. 2-adrenergic agonist salbutamol influences the volume of the sexually dimorphic nucleus in the preoptic area. Brain Research 516, 257-62.
41. KALRA, S. P. & KALRA, P. S. (1983) Neural regulation of luteinizing hormone secretion in the rat. Endocrine Reviews 3, 311-51.
42. KELLEY, D. B. (1988) Sexually dimorphic behaviors. Annual Review of Neuroscience 11, 225-51.
43. KERCHNER, M. & WARD, I. L. (1992) SDN-MPOA volume in male rats is decreased by prenatal stress, but is not related to ejaculatory behavior. Brain Research 581, 244-51.
44. KONIGSMARK, B. W. (1970) Methods for the counting of neurons. In Contemporary Research Methods in Neuroanatomy (edited by Nauta, W. J. H. & Ebbesson S. O. E.) pp. 315-340. New York: Springer-Verlag.
45. KROUSTRUP, J. P. & GUNDERSEN, H. J. G. (1983) Sampling problems in a heterogeneous organ: Quantitation of relative and total volume of pancreatic islets by light microscopy. Journal of Microscopy 132, 43-55.
46. LANGUB, M. C., MALEY, B. E. & WATSON, R. E. (1994) Estrous cycle-associated axosomatic synaptic plasticity upon estrogen receptive neurons in the rat preoptic area. Brain Research 641, 303-10.
47. LEAL, S., ANDRADE, J. P., PAULA-BARBOSA, M. M. & MADEIRA, M. D. (1998) Arcuate nucleus of the hypothalamus: Effects of age and sex. Journal of Comparative Neurology 401, 65-88.
48. LENT, R. & SCHMIDT, S. L. (1993) The ontogenesis of the forebrain commissures and the determination of brain asymmetries. Progress in Neurobiology 40, 249-76.
49. LING, E. A., PATERSON, J. A., PRIVAT, A., MORI, S. & LEBLOND, C. P. (1973) Investigation of glial cells in semithin sections. I. Identification of glial cells in the brain of young rats. Journal of Comparative Neurology 149, 43-72.
50. MADEIRA, M. D. & LIEBERMAN, A. R. (1995) Sexual dimorphism in the mammalian limbic system. Progress in Neurobiology 45, 275-333.
51. MADEIRA, M. D., SOUSA, N., CADETE-LEITE, A., LIEBERMAN, A. R. & PAULA-BARBOSA, M. M. (1993) The supraoptic nucleus of the adult rat hypothalamus displays marked sexual dimorphism which is dependent on body weight. Neuroscience 52, 497-513.
52. MADEIRA, M. D., SOUSA, N., SANTER, R. M., PAULA-BARBOSA, M. M. & GUNDERSEN, H. J. G. (1995) Age and sex do not affect the volume, cell numbers, or cell size of the suprachiasmatic nucleus of the rat: An unbiased stereological study. Journal of Comparative Neurology 361, 585-601.
53. MADEIRA, M. D., ANDRADE, J. P., LIEBERMAN, A. R., SOUSA, N., ALMEIDA, O. F. X. & PAULA-BARBOSA, M. M. (1997) Chronic alcohol consumption and withdrawal do not induce cell death in the suprachiasmatic nucleus, but lead to irreversible depression of peptide immunoreactivity and mRNA levels. Journal of Neuroscience 17, 1302-19.
54. MAYHEW, T. M. & GUNDERSEN, H. J. G. (1996) "If you assume, you can make an ass out of u and me": A decade of the disector for stereological counting of particles in 3D space. Journal of Anatomy 188, 1-15.
55. MØLLER, A., STRANGE, P. & GUNDERSEN, H. J. G. (1990) Efficient estimation of cell volume and number using the nucleator and the disector. Journal of Microscopy 159, 61-71.
56. RAISMAN, G. & FIELD, P. M. (1973) Sexual dimorphism in the neuropil of the preoptic area of the rat and its dependence on neonatal androgen. Brain Research 54, 1-29.
57. REIER, P. J., CULLEN, M. J., FROELICH, J. S. & ROTHCHILD, I. (1977) The ultrastructure of the developing medial preoptic nucleus in the postnatal rat. Brain Research 122, 415-36.
58. RHEES, R. W., SHRYNE, J. E. & GORSKI, R. A. (1990) Termination of the hormone-sensitive period for differentiation of the sexually dimorphic nucleus of the preoptic area in male and female rats. Developmental Brain Research 52, 17-23.
59. ROBINSON, S. M., FOX, T. O., DIKKES, P. & PEARLSTEIN, R. A. (1986) Sex differences in the shape of the sexually dimorphic nucleus of the preoptic area and suprachiasmatic nucleus of the rat: 3-D computer reconstructions and morphometrics. Brain Research 371, 380-84.
60. SHAPIRO, L. E., LEONARD, C. M., SESSIONS, C. E., DEWSBURY, D. A. & INSEL T. R. (1991) Comparative neuroanatomy of the sexually dimorphic hypothalamus in monogamous and polygamous voles. Brain Research 541, 232-40.
61. SIMERLY, R. B. & SWANSON, L. W. (1986) The organization of neural inputs to the medial preoptic nucleus of the rat. Journal of Comparative Neurology 246, 312-42.
62. SIMERLY, R. B. & SWANSON, L. W. (1988) Projections of the medial preoptic nucleus: A Phaseolus vulgaris leucoagglutinin anterograde tract-tracing study in the rat. Journal of Comparative Neurology 270, 209-42.
63. SIMERLY, R. B., SWANSON, L. W. & GORSKI, R. A. (1984) Demonstration of a sexual dimorphism in the distribution of serotonin-immunoreactive fibers in the medial preoptic nucleus of the rat. Journal of Comparative Neurology 225, 151-66.
64. SIMERLY, R. B., GORSKI, R. A. & SWANSON, L. W. (1986) Neurotransmitter specificity of cells and fibers in the medial preoptic nucleus: An immunocytochemical study in the rat. Journal of Comparative Neurology 246, 343-63.
65. SIMERLY, R. B., CHANG, C., MURAMATSU, M. & SWANSON, L. W. (1990) Distribution of androgen and estrogen receptor mRNA-containing cells in the rat brain: An in situ hybridization study. Journal of Comparative Neurology 294, 76-95.
66. STENSAAS, L. J. (1967) The development of hippocampal and dorsolateral pallial regions of the cerebral hemisphere in fetal rabbits. I. Fifteen milimeter stage, spongioblast morphology. Journal of Comparative Neurology 129, 59-70.
67. STEWART, J. & KOLB, B. (1988) The effects of neonatal gonadectomy and prenatal stress on cortical thickness and asymmetry in rats. Behavioral and Neural Biology 49, 144-60.
68. TANDRUP, T., GUNDERSEN, H. J. G. & JENSEN, E. B. V. (1997) The optical rotator. Journal of Microscopy 186, 108-20.
69. TANG, Y. & NYENGAARD, J. R. (1997) A stereological method for estimating the total length and size of myelin fibers in human brain white matter. Journal of Neuroscience Methods 73, 193-200.
70. TARTTELIN, M. F. & GORSKI, R. A. (1988) Postnatal influence of diethylstilbestrol on the differentiation of the sexually dimorphic nucleus in the rat is as effective as perinatal treatment. Brain Research 456, 271-74.
71. TORAN-ALLERAND, C. D. (1980) Sex steroids and the development of the newborn mouse hypothalamus and preoptic area in vitro. II. Morphological correlates and hormonal specificity. Brain Research 189, 413-27.
72. UYLINGS, H. B. M., RUIZ-MARCOS, A. & VAN PELT, J. (1986) The metric analysis of three-dimensional dendritic tree patterns: A methodological review. Journal of Neuroscience Methods 18, 127-51.
73. WEST, M. J., SLOMIANKA, L. & GUNDERSEN, H. J. G. (1991) Unbiased stereological estimation of the total number of neurons in the subdivisions of the rat hippocampus using the optical fractionator. Anatomical Record 231, 482-97.
74. WEST, M. J., ØSTERGAARD, K., ANDREASSEN, O. A. & FINSEN, B. (1996) Estimation of the number of somatostatin neurons in the striatum: An in situ hybridization study using the optical fractionator method. Journal of Comparative Neurology 370, 11-22.
75. YOUNG, J. K. (1982) A comparison of hypothalami of rats and mice: Lack of gross sexual dimorphism in the mouse. Brain Research 239, 233-39.
76. ZOELLER, R. T. & YOUNG, W. S. (1988) Changes in cellular levels of messenger ribonucleic acid encoding gonadotropin releasing hormone in the anterior hypothalamus of female rats during the estrous cycle. Endocrinology 123, 1688-89.