Multipoint interphase FISH analysis of chromosome 3 abnormalities in 28 childhood AML patients

European Journal of Haematology

Volumn 76, Issue 2, 2006, Pages 124-133

  Haltrich, Irén ^a,b   Kost Alimova, Maria ^b   Kovács, Gábor ^a   Klein, George ^b   Fekete, György ^a   Imreh, Stefan ^b  

^a SEMMELWEIS UNIVERSITY   (Hungary)

^b KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Childhood AML; Elimination test; Isodisomy; MDS1 EVI1; Multipoint interphase FISH; Trisomy 3

Indexed keywords

ACUTE GRANULOCYTIC LEUKEMIA; ACUTE MYELOBLASTIC LEUKEMIA; ADOLESCENT; ADULT; ARTICLE; BONE MARROW; CHILD; CHROMOSOME 3P; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; CHROMOSOME DELETION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; GENE LOCUS; HUMAN; MALE; PEDIATRICS; PRIORITY JOURNAL; TETRASOMY; TRISOMY; UNIPARENTAL DISOMY;

ACUTE DISEASE; ADOLESCENT; CHILD; CHILD, PRESCHOOL; CHROMOSOME ABERRATIONS; CHROMOSOMES, HUMAN, PAIR 3; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; INFANT; INTERPHASE; LEUKEMIA, MYELOID; MALE;

EID: 33645089689     PISSN: 09024441     EISSN: 16000609     Source Type: Journal    
DOI: 10.1111/j.1600-0609.2005.00576.x     Document Type: Article

References (46)

1. I mreh S K holodnyuk I A llikmetts R S tanbridge JE Z abarovsky RE K lein G Nonrandom loss of human chromosome 3 fragments from mouse-human microcell hybrids following progressive growth in SCID mice Genes Chromosomes Cancer 1994 11 237 245
2. Y ang Y K ost -A limova M I ngvarsson S Q ianhui Q K iss H S zeles A K holodnyuk I C uthbert A K lein G I mreh S Similar regions of human chromosome 3 are eliminated from or retained in human/human and human/mouse microcell hybrids during tumor growth in severe combined immunodeficient (SCID) mice Proc Natl Acad Sci USA 2000 98 1136 1141
3. I mreh S K lein G Z abarovsky RE Search for unknown tumor-antagonizing genes Genes Chromosomes Cancer 2003 38 307 321
4. K nuutila S A alto Y A utio K B jorkqvist AM E l -R ifai W H emmer S H uhta T K ettunen E K iuru -K uhlefelt S L arramendy ML L ushnikova T M onni O P ere H T apper J T arkkanen M V aris A W asenius VM W olf M Z hu Y DNA copy number losses in human neoplasms Am J Pathol 1999 155 683 694
5. A limov A K ost -A limova M L iu J L i C B ergerheim U I mreh S K lein G Z abarovsky ER Combined LOH/CGH analysis proves the existence of interstitial 3p deletions in renal cell carcinoma Oncogene 2000 19 1392 1399
6. M itelman F J ohansson B M ertens F eds Mitelman Database of Chromosome Aberrations in Cancer 2004 q5
7. J ohansson B B illström R K ristoffersson U Åkerman M G arwicz S A hlgren T M alm C M itelman F Deletion of chromosome arm 3p in hematologic malignancies Leukemia 1997 11 1207 1213
8. M auritzson N A lbin M R ylander L B illstrom R A hlgren T M ikoczy Z B jork J S tromberg U N ilsson PG M itelman F H agmar L J ohansson B Pooled analysis of clinical and cytogenetic features in treatment-related and de novo adult acute myeloid leukemia and myelodysplastic syndromes based on a consecutive series of 761 patients analyzed 1976-1993 and on 5098 unselected cases reported in the literature 1974-2001 Leukemia 2002 16 2366 2378
9. G rimwade D W alker H O liver F W heatley K H arrison C H arrison G R ees J H ann I S tevens R B urnett A G oldstone A The importance of diagnostic cytogenetics on outcome in AML: analysis of 1612 patients entered into the MRC AML 10 trial The Medical Research Council Adult and Children's Leukaemia Working Parties Blood 1998 92 2322 2333
10. F orestier E H eim S B lennow E B orgstrom G H olmgren G H einonen K J ohannsson J K erndrup G A ndersen MK L undin C N ordgren A R osenquist R S wolin B J ohansson B Nordic Society of Paediatric Haematology and Oncology (NOPHO) Swedish Cytogenetic Leukaemia Study Group (SCLSG) NOPHO Leukaemia Cytogenetic Study Group (NLCSG) Cytogenetic abnormalities in childhood acute myeloid leukaemia: a Nordic series comprising all children enrolled in the NOPHO-93-AML trial between 1993 and 2001 Br J Haematol 2003 121 566 577
11. M rozek K H eerema NA B loomfield CD Cytogenetics in acute leukemia Blood 2004 18 115 136
12. B ennett JM C atovsky D D aniel MT F landrin G G alton DA G ralnick HR S ultan C Proposed revised criteria for the classification of acute myeloid leukemia A report of the French-American-British Cooperative Group Ann Intern Med 1985 103 620 625
13. Y ang Y K iss H K ost -A limova M K edra D F ransson I S eroussi E L i J S zeles A K holodnyuk I I mreh MP F odor K H adlaczky GY K lein G D umanski JP I mreh S 1-Mb PAC contig spanning the common eliminated region 1 (CER1) in microcell hybrid-derived SCID tumors Genomics 1999 6 147 157
14. K iss H Y ang Y K iss C A ndersson K K lein G I mreh S D umanski JP The transcriptional map of the common eliminated region (C3CER1) in 3p21.3 Eur J Hum Genet 2002 10 52 61
15. Y ang Y A limova MK I ngvarsson S Q ianhui Q K iss H S zeles A C uthbert A K lein G I mreh S 'Elimination test (Et)' identifies similar 3p regions, including CER1 at 3p21.3, in the human/human and in human/mouse microcell hybrid derived tumors Proc Natl Acad Sci USA 2001 98 1136 1141
16. R aimondi SC C hang MN R avindranath Y B ehm FG G resik MV S teuber CP W einstein HJ C arroll AJ Chromosomal abnormalities in 478 children with acute myeloid leukemia: clinical characteristics and treatment outcome in a cooperative pediatric oncology group study-POG 8821 Blood 1999 94 3707 3716
17. J ohansson B M ertens F M itelman F Geographic heterogeneity of neoplasia-associated chromosome aberrations Genes Chromosomes Cancer 1991 3 1 7
18. A rana -T rejo RM G omez -M orales E R ubio -B orja ME K assack -I pina JJ C ervantes -P eredo A G uerrero -R ivera S G onzalez -L laven J G utierrez -R omero M P izzuto -C havez J K ofman -A lfaro S Cytogenetic findings in 303 Mexican patients with de novo acute myeloblastic leukemia Arch Med Res 1997 28 209 214
19. C harrin C B elhabri A T reille -R itouet D T heuil G M agaud JP F iere D T homas X Structural rearrangements of chromosome 3 in 57 patients with acute myeloid leukemia: clinical, hematological and cytogenetic features Hematol J 2002 3 21 31
20. S uzukawa K P arganas E G ajjar A A be T T akahashi S T ani K A sano S A sou H K amada N Y okota J M orishita K I hle JN Identification of a breakpoint cluster region 3′ of the ribophorin I gene at 3q21 associated with the transcriptional activation of the EVI1 gene in acute myelogenous leukemias with inv(3)(q21q26) Blood 1994 84 2681 2688
21. R ynditch A P ekarsky Y S chnittger S G ardiner K Leukemia breakpoint region in 3q21 is gene rich Gene 1997 193 49 57
22. W ieser R S chreiner U P irc -D anoewinata H A ytekin M S chmidt HH R ieder H F onatsch C Interphase fluorescence in situ hybridization assay for the detection of 3q21 rearrangements in myeloid malignancies Genes Chromosomes Cancer 2001 32 373 380
23. W alter TA M organ R O ndreyco S S andberg AA Apparent duplication of inv(3)(q21q26) in one of five cases with inv (3) in myelodysplastic syndromes and acute leukemia Am J Hematol 1990 33 210 214
24. M onni O O inonen R E lonen E F ranssila K T eerenhovi L J oensuu H K nuutila S Gain of 3q and deletion of 11q22 are frequent aberrations in mantle cell lymphoma Genes Chromosomes Cancer 1998 21 298 307
25. B ea S R ibas M H ernandez JM B osch F P inyol M H ernandez L G arcia JL F lores T G onzalez M L opez -G uillermo A P iris MA C ardesa A M ontserrat E M iro R C ampo E Increased number of chromosomal imbalances and high-level DNA amplifications in mantle cell lymphoma are associated with blastoid variants Blood 1999 93 4365 4374
26. G azzo S B aseggio L C oignet L P oncet C M orei D C oiffier B F elman P B erger F S alles G C allet -B auchu E Cytogenetic and molecular delineation of a region of chromosome 3q commonly gained in marginal zone B-cell lymphoma Haematologica 2003 88 31 38
27. T onnies H H uber S K uhl JS G erlach A E bell W N eitzel H Clonal chromosomal aberrations in bone marrow cells of Fanconi anemia patients: gains of the chromosomal segment 3q26q29 as an adverse risk factor Blood 2003 101 3872 3874
28. R eis MD D ube ID P inkerton PH C hen -L ai J R obinson JB K lock RJ S enn JS 'Jumping' translocations involving band 3q13.3 in a case of acute monocytic leukemia Cancer Genet Cytogenet 1991 51 189 194
29. M ichalova K B artsch O S tary J J elinek J W iegant J B ubanska E Partial trisomy of 3q detected by chromosome painting in a case of juvenile chronic myelomonocytic leukemia Cancer Genet Cytogenet 1993 71 67 70
30. T osi S M osna G C azzaniga G G iudici G K earney L B iondi A P rivitera E Unbalanced t(3;12) in a case of juvenile myelomonocytic leukemia (JMML) results in partial trisomy of 3q as defined by FISH Leukemia 1997 11 1465 1468
31. M orishita K P arganas E W illiam CL W hittaker MH D rabkin H O val J T aetle R V alentine MB I hle JN Activation of EVI1 gene expression in human acute myelogenous leukemias by translocations spanning 300-400 kilobases on chromosome band 3q26 Proc Natl Acad Sci USA 1992 89 3937 3941
32. M artinelli G O ttaviani E B uonamici S I sidori A B orsaru G V isani G P iccaluga PP M alagola M T estoni N R ondoni M N ucifora G T ura S B accarani M Association of 3q21q26 syndrome with different RPN1/EVI1 fusion transcripts Haematologica 2003 88 1221 1228
33. N ucifora G The EVI1 gene in myeloid leukemia Leukemia 1997 11 2022 2031
34. P ekarsky Y R ynditch A W ieser R F onatsch C G ardiner K Activation of a novel gene in 3q21 and identification of intergenic fusion transcripts with ecotropic viral insertion site I in leukemia Cancer Res 1997 57 3914 3919
35. K reider BL O rkin SH I hle JN Loss of erythropoietin responsiveness in erythroid progenitors due to expression of the Evi-1 myeloid-transforming gene Proc Natl Acad Sci USA 1993 90 6454 6458
36. T estoni N B orsaru G M artinelli G C arboni C R uggeri D O ttaviani E P elliconi S R icci P P astano R V isani G Z accaria A T ura S 3q21 and 3q26 cytogenetic abnormalities in acute myeloblastic leukemia: biological and clinical features Haematologica 1999 84 690 694
37. J ohansson B F ioretos T G arwicz S H eim S M itelman F t(3;21)(q26;q22) with AML1 rearrangement in a de novo childhood acute monoblastic leukaemia Br J Haematol 1996 92 429 431
38. M otomura S F ujisawa S T sunooka S F ujimaki K H arano H M ohri H O kubo T F ujita H M aruta A K odama F Translocation (3;21)(q26;q22) in de novo acute myelogenous leukemia Leukemia 1997 11 172 173
39. H altrich I M üller J S zabó J K ovács G K oós R P oros A D obos M F ekete GY Donor-cell myelodysplastic syndrome developing 13 years after marrow grafting for aplastic anemia Cancer Genet Cytogenet 2003 142 124 128
40. R ubin CM L arson RA A nastasi J W inter JN T hangavelu M V ardiman JW R owley JD L e B eau MM t(3;21)(q26;q22): a recurring chromosomal abnormality in therapy-related myelodysplastic syndrome and acute myeloid leukemia Blood 1990 76 2594 2598
41. M iyoshi H S himizu K K ozu T M aseki N K aneko Y O hki M t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1 Proc Natl Acad Sci USA 1991 88 10431 10434
42. G olub TR B arker GF B ohlander SK H iebert SW W ard DC B ray -W ard P M organ E R aimondi SC R owley JD G illiland DG Fusion of the TEL gene on 12p13 to the AML1 gene on 21q22 in acute lymphoblastic leukemia Proc Natl Acad Sci USA 1995 92 4917 4921
43. N ucifora G R owley JD AML1 and the 8;21 and 3;21 translocations in acute and chronic myeloid leukemia Blood 1995 86 1 14
44. Z ent C K im N H iebert S Z hang DE T enen DG R owley JD N ucifora G Rearrangement of the AML1/CBFA2 gene in myeloid leukemia with the 3;21 translocation: expression of co-existing multiple chimeric genes with similar functions as transcriptional repressors, but with opposite tumorigenic properties Curr Top Microbiol Immunol 1996 211 243 252
45. C uenco GM R en R Both AML1 and EVI1 oncogenic components are required for the cooperation of AML1/MDS1/EVI1 with BCR/ABL in the induction of acute myelogenous leukemia in mice Oncogene 2004 23 569 579
46. L indvall C N ordenskjold M P orwit A B jorkholm M B lennow E Molecular cytogenetic characterization of acute myeloid leukemia and myelodysplastic syndromes with multiple chromosome rearrangements Haematologica 2001 86 1158 1164