Polymorphisms in the DBH and DRD2 gene regions and smoking behavior

European Archives of Psychiatry and Clinical Neuroscience

Volumn 256, Issue 2, 2006, Pages 93-97

  Freire, Maria Teresa M V ^a   Marques, Francine Z C ^a   Hutz, Mara H ^a   Bau, Claiton H D ^a  

^a FEDERAL UNIVERSITY OF RIO GRANDE DO SUL   (Brazil)

Author keywords

Alcoholism; Dependence; Dopamine; Nicotine

Indexed keywords

DOPAMINE 2 RECEPTOR; DOPAMINE BETA MONOOXYGENASE;

ALCOHOLISM; ALLELE; ARTICLE; CONTROLLED STUDY; GENE FREQUENCY; GENETIC POLYMORPHISM; GENOTYPE; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; SMOKING;

EID: 33645066374     PISSN: 09401334     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00406-005-0610-x     Document Type: Article

References (44)

1. rd ed. Washington, DC: American Psychiatric Association
2. Bau CHD, Almeida S, Hutz MH (2000) The TaqI A1 allele of the dopamine D2 receptor gene and alcoholism in Brazil: association and interaction with stress and harm avoidance on severity prediction. Am J Med Genet 96:302-306
3. Bucholz KK, Cadoret R, Cloninger CR, Dinwiddie SH, Hesselbrock VM, Nurnberger JI, Reich T, Schmidt I, Schuckit MA (1994) A new, semistructured psychiatric interview for use in genetic linkage studies: a report of the reliability of SSAGA. J Stud Alcohol 55:149-158
4. Craig SP, Buckle VJ, Lamouroux A, Mallet J, Craig IW (1988) Localization of the human dopamine beta hydroxylase (DBH) gene to chromosome 9q34. Cytogenet Cell Genet 48:48-50
5. Cubells JF, Van Kammen DP, Kelley ME, Anderson GM, O'Connor DT, Price LH, Malison RT, Rao PA, Kobayaski K, Nagatsu T, Gelernter J (1998) Dopamine β-hydroxylase: two polymorphisms in linkage disequilibrium at the structural gene DBH associate with biochemical phenotypic variation. Hum Genet 102:533-540
6. Cubells JF, Kranzler HR, McCance-Katz E, Anderson GM, Malison RT, Price LH, Gelernter J (2000) A haplotype at the DBH locus, associated with low plasma dopamine β-hydroxylase activity, also associates with cocaine-induced paranoia. Mol Psychiatry 5:56-63
7. Cubells JF, Price LH, Meyers BS, Anderson GM, Zabetian CP, Alexopoulos GS, Nelson JC, Sanacora, G, Kirwin P, Carpenter L, Malison RT, Gelernter J (2002) Genotype-controlled analysis of plasma dopamine β-hydroxylase activity in psychotic unipolar major depression. Biol Psychiatry 51:358-364
8. Cubells JF, Zabetian CP (2004) Human genetics of plasma dopamine beta-hydroxylase activity: applications to research in psychiatry and neurology. Psychopharmacology 174:463-476
9. Dubertret C, Gouya L, Hanoun N, Deybach J, Ades J, Hamon M, Gorwood F (2004) The 3′ region of the DRD2 gene is involved in genetic susceptibility to schizophrenia. Schizophr Res 67:75-85
10. Ewing JA (1984) Detecting alcoholism: the CAGE questionnaire. JAMA 252:1905-1907
11. Galvin M, Shekhar A, Simon J, Stilwell B, TanEyck R, Laite G, et al. (1991) Low dopamine-beta-hydroxylase: a biological sequela of abuse and neglect? Psychiatry Res 39:1-11
12. Gilbert DG, McLernon J, Rabinovich NE, Sugai C, Plath LC, Asgaard G, Zuo Y, Huggenvik J, Botros N (2004) Effects of quitting smoking on EEG activation and attention last for more than 31 days and are more severe with stress, dependence, DRD2 A1 allele, and depressive traits. Nicotine and Tobacco Research 6: 249-267
13. Grandy DK, Litt M, Allen L, Bunzow JR, Marchionni M, Makam H, Reed L, Magenis RE, Civelli O (1989) The human dopamine D2 receptor gene is located on chromosome 11 at q22-q23 and identifies a TaqI RFLP. Am J Hum Genet 45:778-785
14. Grandy DK, Zhang Y, Civelli O (1993) PCR detection of the TaqA RFLP at the DRD2 locus. Hum Mol Genet 2:2197
15. Instituto Brasileiro de Geografia e Estatística. Censo Demográfico 2000. Rio de Janeiro: IBGE. 2002
16. Johnson BA (2004) Topiramate-induced neuromodulation of cortico-mesolimbic dopamine function: a new vista for the treatment of comorbid alcohol and nicotine dependence? Addict Behav 29:1465-1479
17. Johnstone EC, Clark TG, Griffiths S, Murphy MFG, Walton RT (2002) Polymorphisms in dopamine metabolic enzymes and tobacco consumption in smokers: seeking confirmation of the association in a follow-up study. Pharmacogenetics 12:1-3
18. Johnstone EC, Yudkin PL, Hey K, Roberts SJ, Welch SJ, Murphy MF, Griffiths SE, Walton RT (2004) Genetic variation in dopaminergic pathways and short-term effectiveness of the nicotine patch. Pharmacogenetics 14:83-90
19. Jonsson EG, Nothen MM, Grunhage F, Farde L, Nakashima Y, Propping P, Sedvall GC (1999) Polymorphisms in the dopamine D2 receptor gene and their relationships to striatal dopamine receptor density of healthy volunteers. Mol Psychiatry 4:290-296
20. Kohnke MD, Zabetian CP, Anderson GM, Kolb W, Gaertner I, Buchkremer G, Vonthein R, Schick S, Lutz U, Kohnke AM, Cubells JF (2002) A genotype-controlled analysis of plasma dopamine β-hydroxylase in healthy and alcoholic subjects: evidence for alcohol-related differences in noradrenergic function. Biol Psychiatry 52:1151-1158
21. Lahiri DK, Nurnberger JI (1991) A rapid non-enzimatic method for the preparation of HMW DNA from blood for RFLP studies. Nucleic Acids Res 19:5444
22. Li MD, Ma JZ, Beuten J (2004) Progress in searching for susceptibility loci and genes for smoking-related behavior. Clin Genet 66:382-392
23. Mayhew KP, Flay BR, Mott JA (2000) Stages in the development of adolescent smoking. Drug and Alcohol Dependence 59:61-81
24. McKinney EF, Walton RT, Yudkin P, Fuller A, Haldar NA, Mant D, Murphy M, Welsh KI, Marshall SE (2000) Association between polymorphisms in dopamine metabolic enzymes and tobacco consumption in smokers. Pharmacogenetics 10:1-9
25. Munafò MR, Clark TG, Johnstone EC, Murphy MFG, Walton RT (2004) The genetic basis for smoking behavior: a systematic review and meta-analysis. Nicotine and Tobacco Research 6:1-15
26. Neville MJ, Johnstone EC, Walton RT (2004) Identification and characterization of ANKK1: a novel kinase gene closely linked to DRD2 on chromosome band 11q23.1. Hum Mutat 23:540-545
27. Noble EP, Blum K, Ritchie T, Montgomery A, Sheridan PJ (1991) Allelic association of the D2 dopamine receptor gene with receptor-binding characteristics in alcoholism. Arch Gen Psychiatr 48:648-654
28. Noble EP, Gottschalk LA, Fallon JH, Ritchie TL, Wu JC (1997) D2 dopamine receptor polymorphism and brain regional glucose metabolism. Am J Med Genet 74:162-166
29. Noble EP (2003) D2 dopamine receptor gene in psychiatric and neurologic disorders and its phenotypes. Am J Med Genet Neuropsychiatr Genet 116:103-125
30. Pohjalainen T, Rinne JO, Nagren K, Lehikoinen P, Anttila K, Syvalahti EK, Hietala J (1998) The A1 allele of the human D2 dopamine receptor gene predicts low D2 receptor availability in healthy volunteers. Mol Psychiatry 3:256-260
31. Rogeness GA, Hernandez JM, Macedo CA, Mitchell EL, Amrung AS, Harris WR (1984) Clinical characteristics of emotionally disturbed boys with very low activities of dopamine β-hydroxylase. J Am Acad Child Adolesc Psychiatry 23:203-208
32. Rogeness GA, Hernandez JM, Macedo CA, Amrung AS, Hoppe SK (1986) Near-zero plasma dopamine β-hydroxylase and conduct disorder in emotionally disturbed boys. J Am Acad Child Adolesc Psychiatry 25:521-527
33. Rogeness GA, Javors MA, Maas JW, Macedo CA, Fisher C (1987) Plasma dopamine-beta-hydroxylase, HVA, MHPG and conduct disorder in emotionally disturbed boys. Biol Psychiatry 22: 1155-1158
34. Rogeness GA, Maas JW, Javors MA, Macedo CA, Harris WR, Hoppe SK (1988) Diagnoses, catecholamine metabolism, and plasma dopamine β-hydroxylase. J Acad Child Adolesc Psychiatry 27:121-125
35. Salzano FM, Freire-Maia N (1970) Problems in Human Biology. A Study of Brazilian Populations. Detroit: Wayne State University Press
36. Salzano FM, Bortolini MC (2002) The Evolution and Genetics of Latin American Populations. Cambridge: Cambridge University Press
37. Shoaib M, Lowe AS, Williams SCR (2004) Imaging localized dynamic changes in the nucleus accumbens following nicotine withdrawal in rats. Neuroimage 22:847-854
38. Thompson J, Thomas N, Singleton A, Piggott M, Lloyd S, Perry EK, Morris CM, Perry RH, Ferrier IN, Court JA (1997) D2 dopamine receptor gene (DRD2) Taq1 A polymorphism: reduced dopamine D2 receptor binding in the human striatum associated with the A1 allele. Pharmacogenetics 7:479-484
39. True WR, Xian H, Scherrer JF, Madden PAF, Bucholz KK, Heath AC, Eisen SA, Lyons MJ, Goldberg J, Tsuang M (1999) Common genetic vulnerability for nicotine and alcohol dependence in men. Arch Gen Psychiatry 56:655-661
40. Wei J, Xu H, Ramchand CN, Hemmings GP (1997) Is the polymorphic microsatellite repeat of the dopamine β-hydroxylase gene associated with biochemical variability of the catecholamine pathway in schizophrenia? Biol Psychiatry 41: 762-767
41. Wei J, Ramchand CN, Hemmings GP (1998) TaqI polymorphic sites at the human dopamine β-hydroxylase gene possibly associated with biochemical alterations of the catecholamine pathway in schizophrenia. Psychiatr Genet 8:19-24
42. Wellman RJ, DiFranza JR, Savageau JA, Dussault GF (2004) Short term patterns of early smoking acquisition. Tob Control 13:251-257
43. Zabetian CP, Anderson GM, Buxbaum SG, Elston RC, Ichinose H, Nagatsu T, Kim KS, Kim CH, Malison RT, Gelernter J, Cubells JF (2001) A Quantitative-trait analysis of plasma-dopamine β-hydroxylase activity: evidence for a major functional polymorphism at the DBH Locus. Am J Hum Genet 68:515-522
44. Zabetian CP, Buxbaum SG, Elston RC, Kohnke MD, Anderson GM, Gelernter J, Cubells JF (2003) The structure of linkage disequilibrium at the DBH locus strongly influences the magnitude of association between diallelic markers and plasma dopamine β-hydroxylase activity. Am J Hum Genet 72:1389-1400