Evidence for linkage and association between autoimmune thyroid diseases and the 18q12-q21 region in a large Tunisian family

International Journal of Immunogenetics

Volumn 33, Issue 1, 2006, Pages 25-32

  Hadj Kacem, H ^a   Rebai, A ^b   Kaffel, N ^c   Abid, M ^c   Ayadi, H ^a,b  

^a UNIVERSITY OF SFAX   (Tunisia)

^b CENTRE DE BIOTECHNOLOGIE DE SFAX   (Tunisia)

^c HEDI CHAKER HOSPITAL   (Tunisia)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN TRANSCRIPTION FACTOR; PROTEIN BCL 2; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ALLELE; ARTICLE; AUTOIMMUNE DISEASE; CASE CONTROL STUDY; CHROMOSOME 18Q; CHROMOSOME REPLICATION; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; DNA FLANKING REGION; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENE LOCUS; GENETIC LINKAGE; GENETIC SUSCEPTIBILITY; GENOTYPE; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; LINKAGE ANALYSIS; MAJOR CLINICAL STUDY; MALE; MICROSATELLITE MARKER; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SCORING SYSTEM; SINGLE NUCLEOTIDE POLYMORPHISM; STATISTICAL SIGNIFICANCE; THYROID DISEASE; TRANSCRIPTION INITIATION SITE; TUNISIA;

AUTOIMMUNE DISEASES; CASE-CONTROL STUDIES; FEMALE; GENES, BCL-2; GENETIC MARKERS; GENETIC PREDISPOSITION TO DISEASE; GENETIC SCREENING; HUMANS; INHERITANCE PATTERNS; LINKAGE (GENETICS); MALE; POLYMORPHISM, GENETIC; TCF TRANSCRIPTION FACTORS; THYROID DISEASES; THYROIDITIS, AUTOIMMUNE; TUNISIA;

EID: 33645054310     PISSN: 17443121     EISSN: 1744313X     Source Type: Journal    
DOI: 10.1111/j.1744-313X.2005.00554.x     Document Type: Article

References (44)

1. Abecasis G.R. Cherny S.S. Cookson W.O. Cardon L.R. 2002 Merlin-rapid analysis of dense genetic map using sparse gene flow trees Nature Genetics 30 97
2. Allen E.M. Hsueh W.C. Sabra M.M. Pollin T.I. Ladenson P.W. Silver K.D. Mitchell B.D. Shuldiner A.R. 2003 A genome-wide scan for autoimmune thyroiditis in the Old Order Amish: replication of genetic linkage on chromosome 5q11.2-q14.3 Journal of Clinical Endocrinology and Metabolism 88 1292
3. Ayadi H. Hadj Kacem H. Rebai A. Farid N.R. 2004 The genetics of autoimmune thyroid disease Trends in Endocrinology and Metabolism 15 234
4. Baker D. Rosenwasser O.A. O'Neill J.K. Turk J.L. 1995 Genetic analysis of experimental allergic encephalomyelitis in mice Journal of Immunology 155 4046
5. Ban Y. Ban Y. Taniyama M. Katagiri T. 2000a Vitamin D receptor initiation codon polymorphism in Japanese patients with Graves' disease Thyroid 10 475
6. Ban Y. Taniyama M. Ban Y. 2000b Vitamin D receptor gene polymorphism is associated with Graves' disease in the Japanese population Journal of Clinical Endocrinology and Metabolism 85 4639
7. Ban Y. Taniyama M. Ban Y. 2001 Vitamin D receptor gene polymorphisms in Hashimoto's thyroiditis Thyroid 11 607
8. Breschel T.S. McInnis M.G. Margolis R.L. Sirugo G. Corneliussen B. Simpson S.G. et al. 1997 A novel, heritable, expanding CTG repeat in an intron of the SEF2-1 gene on chromosome 18q21.1 Human Molecular Genetics 6 1855
9. Bureau J.F. Montagutelli X. Bihl F. Lefebvre S. Guenet J.L. Brahic M. 1993 Mapping loci influencing the persistence of Theiler's virus in the murine central nervous system Nature Genetics 5 87
10. Cornelis F. Faure S. Martinez M. et al. 1998 New susceptibility locus for rheumatoid arthritis suggested by a genome-wide linkage study Proceedings of the National Academy of Sciences, USA 95 107460
11. Cuddihy R.M. Dutton C.M. Bahn R.S. 1995 A polymorphism in the extracellular domain of the thyrotropin receptor is highly associated with autoimmune thyroid disease in females Thyroid 5 89
12. Curtis D. Sham P.C. 1995 A note on the application of transmission disequilibrium test when a parent is missing American Journal of Human Genetics 56 811
13. Dahlman I. Wallstrom E. Weissert R. et al. 1999 Linkage analysis of myelin oligodendrocyte glycoprotein-induced experimental autoimmune encephalomyelitis in the rat identifies a locus controlling demyelination on chromosome 18 Human Molecular Genetics 8 2183
14. Davies J.L. Kawaguchi Y. Bennett S.T. et al. 1994 A genome-wide search for human type 1 diabetes susceptibility genes Nature 371 130
15. Dib C. Faure S. Fizames C. et al. 1996 A comprehensive genetic map of the human genome based on 5264 microsatellites Nature 380 152
16. Elleuch-Bougacha N. Maalej A. Makni H. et al. 2001 HLA class I and II polymorphisms in a large multiplex family with autoimmune thyroid diseases Clinical Endocrinology (Oxf) 55 557
17. Hadj Kacem H. Bellassoued M. Bougacha-Elleuch N. Abid M. Ayadi H. 2001 CTLA-4 gene polymorphisms in Tunisian patients with Graves' disease Clinical Immunology 101 361
18. Hadj Kacem H. Rebai A. Kaffel N. Masmoudi S. Abid M. Ayadi H. 2003 PDS is a new susceptibility gene to autoimmune thyroid diseases: association and linkage study Journal of Clinical Endocrinology and Metabolism 88 2274
19. Hall R.J. Merriman M.E. Green R.A. et al. 2003 The deleted in colorectal carcinoma (DCC) gene 201 R - > G polymorphism: no evidence for genetic association with autoimmune disease European Journal of Human Genetics 11 840
20. Horvath S. Xu X. Lake S.L. Silverman E.K. Weiss S.T. Laird N.M. 2004 Family-based tests for associating haplotypes with general phenotype data: application to asthma genetics Genetic Epidemiology 26 61
21. Huang Q.R. Morris D. Manolios N. 1996 Evaluation of the BCL-2 gene locus as a susceptibility locus linked to the clinical expression of systemic lupus erythematosus (SLE) Rheumatology International 16 121
22. Hunt P.J. Marshall S.E. Weetman A.P. Bell J.I. Wass J.A. Welsh K.I. 2000 Cytokine gene polymorphisms in autoimmune thyroid disease Journal of Clinical Endocrinology and Metabolism 85 1984
23. Jawaheer D. Seldin M.F. Amos C.I. et al. 2003 Screening the genome for rheumatoid arthritis susceptibility genes: a replication study and combined analysis of 512 multicase families Arthritis and Rheumatism 48 906
24. Jin Y. Teng W. Ben S. et al. 2003 Genome-wide scan of Graves' disease: evidence for linkage on chromosome 5q31 in Chinese Han pedigrees Journal of Clinical Endocrinology and Metabolism 88 1798
25. Johansson C. Castillejo-Lopez C. Johanneson B. et al. 2000 Association analysis with microsatellite and SNP markers does not support the involvement of BCL-2 in systemic lupus erythematosus in Mexican and Swedish patients and their families Genes and Immunity 1 380
26. Kawazaki E. 1990 Sample preparation from blood, cells and other fluids In: PCR ProtocolsA Guide to Methods and Application (eds by Innis M. Gelffand D. Snisky G. White T. p. 146 Academic Press San Diego
27. Kono D.H. Burlingame R.W. Owens D.G. et al. 1994 Lupus susceptibility loci in New Zealand mice Proceedings of the National Academy of Sciences, USA 91 101682
28. Laird N.M. Horvath S. Xu X. 2000 Implementing a unified approach to family-based tests of association Genetic Epidemiology 19 Suppl. 1 36
29. Maalej A. Makni H. Ayadi F. et al. 2001 A full genome screening in a large Tunisian family affected with thyroid autoimmune disorders Genes and Immunity 2 71
30. Makni H. Maalej A. Ayadi F. Abid M. Jouida J. Ayadi H. 1996 Clinical and biological follow up of a family with high prevalence of thyroid autoimmune disease La Tunisie Médicale 74 433
31. Mehrian R. Quismorio F.P. Jr. Strassmann G. et al. 1998 Synergistic effect between IL-10 and bcl-2 genotypes in determining susceptibility to systemic lupus erythematosus Arthritis and Rheumatism 41 596
32. Merriman T. Twells R. Merriman M. et al. 1997 Evidence by allelic association-dependent methods for a type 1 diabetes polygene (IDDM6) on chromosome 18q21 Human Molecular Genetics 6 10030
33. Merriman T.R. Eaves I.A. Twells R.C. et al. 1998 Transmission of haplotypes of microsatellite markers rather than single marker alleles in the mapping of a putative type 1 diabetes susceptibility gene (IDDM6) Human Molecular Genetics 7 517
34. Merriman T.R. Cordell H.J. Eaves I.A. et al. 2001 Suggestive evidence for association of human chromosome 18q12-q21 and its orthologue on rat and mouse chromosome 18 with several autoimmune diseases Diabetes 50 184
35. Riou S. Buresi-Elyounsi C. Chaabouni H. 1989 Etude de la consanguinité dans le nord de la Tunisie La Tunisie Médicale 67 167
36. Sakai K. Shirasawa S. Ishikawa N. et al. 2001 Identification of susceptibility loci for autoimmune thyroid disease to 5q31-q33 and Hashimoto's thyroiditis to 8q23-q24 by multipoint affected sib-pair linkage analysis in Japanese Human Molecular Genetics 10 1379
37. Shai R. Quismorio F.P. Jr. Li L. et al. 1999 Genome-wide screen for systemic lupus erythematosus susceptibility genes in multiplex families Human Molecular Genetics 8 639
38. Sham P.C. Curtis D. 1995 Monte Carlo tests for associations between disease and alleles at highly polymorphic loci Annals of Human Genetics 59 97
39. Spielman R.S. McGinnis R.E. Ewens W.J. 1993 Transmission test for linkage disequilibrium: the insulin gene region and insulin-dependent diabetes mellitus (IDDM) American Journal of Human Genetics 52 506
40. Tanaka S. Kant J. Reed J.C. 1991 G to A polymorphism in the second exon of the BCL2 gene Nucleic Acids Research 19 1964
41. Tomer Y. Concepcion E. Greenberg D.A. 2002a A C/T single-nucleotide polymorphism in the region of the CD40 gene is associated with Graves' disease Thyroid 12 1129
42. Tomer Y. Greenberg D.A. Concepcion E. Ban Y. Davies T.F. 2002b Thyroglobulin is a thyroid specific gene for the familial autoimmune thyroid diseases Journal of Clinical Endocrinology and Metabolism 87 404
43. Ueda H. Howson J.M. Esposito L. et al. 2003 Association of the T-cell regulatory gene CTLA4 with susceptibility to autoimmune disease Nature 423 506
44. Vaidya B. Imrie H. Perros P. et al. 2000 Evidence for a new Grave's disease susceptibility locus at chromosome 18q21 American Journal of Human Genetics 66 1710