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Volumn 126, Issue 4, 2006, Pages 841-848

Heavy water labeling of keratin as a non-invasive biomarker of skin turnover in vivo in rodents and humans

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGICAL MARKER; DEUTERIUM OXIDE; KERATIN;

EID: 33645034938     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1038/sj.jid.5700189     Document Type: Article
Times cited : (25)

References (50)
  • 1
    • 0022961251 scopus 로고
    • Separation of cytokeratin polypeptides by gel electrophoretic and chromatographic techniques and their identification by immunoblotting
    • Achtstaetter T, Hatzfeld M, Quinlan RA, Parmelee DC, Franke WW (1986) Separation of cytokeratin polypeptides by gel electrophoretic and chromatographic techniques and their identification by immunoblotting. Methods Enzymol 134:355-71
    • (1986) Methods Enzymol , vol.134 , pp. 355-371
    • Achtstaetter, T.1    Hatzfeld, M.2    Quinlan, R.A.3    Parmelee, D.C.4    Franke, W.W.5
  • 3
    • 0028850270 scopus 로고
    • The flaky skin (fsn) mutation in mice: Map location and description of the anemia
    • Beamer WG, Pelsue SC, Shultz LD, Sundberg JP, Barker JE (1995) The flaky skin (fsn) mutation in mice: map location and description of the anemia. Blood 86:3220-6
    • (1995) Blood , vol.86 , pp. 3220-3226
    • Beamer, W.G.1    Pelsue, S.C.2    Shultz, L.D.3    Sundberg, J.P.4    Barker, J.E.5
  • 4
    • 33646106593 scopus 로고    scopus 로고
    • Measurement of slow protein turnover rates by heavy water labeling via nonessential amino acids
    • in press
    • Busch R, Kim Y, Neese RA, Schade-Serin V, Collins M, Awada M et al. (2006) Measurement of slow protein turnover rates by heavy water labeling via nonessential amino acids. Biochim Biphys Acta, in press
    • (2006) Biochim Biphys Acta
    • Busch, R.1    Kim, Y.2    Neese, R.A.3    Schade-Serin, V.4    Collins, M.5    Awada, M.6
  • 5
    • 0037840686 scopus 로고    scopus 로고
    • Measurement of mitochondrial DNA synthesis in vivo using a stable isotope-mass spectrometric technique
    • Collins M, Eng S, Hoh R, Hellerstein MK (2003) Measurement of mitochondrial DNA synthesis in vivo using a stable isotope-mass spectrometric technique. J Appl Physiol 94:2203-11
    • (2003) J Appl Physiol , vol.94 , pp. 2203-2211
    • Collins, M.1    Eng, S.2    Hoh, R.3    Hellerstein, M.K.4
  • 7
    • 0009730232 scopus 로고
    • Cell kinetics of keratinocytes
    • (Leigh IM, Lane EB, Watt FM, eds), Cambridge: Cambridge University Press
    • Dover R (1993) Cell kinetics of keratinocytes. In: The keratinocyte handbook (Leigh IM, Lane EB, Watt FM, eds), Cambridge: Cambridge University Press, 203-34
    • (1993) The Keratinocyte Handbook , pp. 203-234
    • Dover, R.1
  • 8
  • 9
    • 9644254222 scopus 로고    scopus 로고
    • In vivo measurement of microtubule dynamics using stable isotope labeling with heavy water
    • Fanara P, Turner S, Busch R, Killion S, Awada M, Turner H et al. (2004) In vivo measurement of microtubule dynamics using stable isotope labeling with heavy water. J Biol Chem 279:49940-7
    • (2004) J Biol Chem , vol.279 , pp. 49940-49947
    • Fanara, P.1    Turner, S.2    Busch, R.3    Killion, S.4    Awada, M.5    Turner, H.6
  • 10
    • 14844320077 scopus 로고    scopus 로고
    • The epidermal skin barrier: Implications for the wound care practitioner, part II
    • Fore-Pfliger J (2004) The epidermal skin barrier: implications for the wound care practitioner, part II. Adv Skin Wound Care 17:480-8
    • (2004) Adv Skin Wound Care , vol.17 , pp. 480-488
    • Fore-Pfliger, J.1
  • 11
    • 0030474645 scopus 로고    scopus 로고
    • The cytoskeleton and disease: Genetic disorders of intermediate filaments
    • Fuchs E (1996) The cytoskeleton and disease: genetic disorders of intermediate filaments. Annu Rev Genet 30:197-231
    • (1996) Annu Rev Genet , vol.30 , pp. 197-231
    • Fuchs, E.1
  • 13
    • 0020640790 scopus 로고
    • Age-associated changes in human epidermal cell renewal
    • Grove GL, Kligman AM (1983) Age-associated changes in human epidermal cell renewal. J Gerontol 38:137-42
    • (1983) J Gerontol , vol.38 , pp. 137-142
    • Grove, G.L.1    Kligman, A.M.2
  • 14
    • 3242728098 scopus 로고    scopus 로고
    • Structure and function of the skin: Overview of the epidermis and dermis
    • (Freinkel R, Woodley D, eds), New York: Parthenon Publishing
    • Haake A, Scott GA, Holbrook KA (2001) Structure and function of the skin: overview of the epidermis and dermis. In: The biology of the skin (Freinkel R, Woodley D, eds), New York: Parthenon Publishing, 19-45
    • (2001) The Biology of the Skin , pp. 19-45
    • Haake, A.1    Scott, G.A.2    Holbrook, K.A.3
  • 15
    • 16844386596 scopus 로고    scopus 로고
    • Interleukin-4 suppresses the enhancement of ceramide synthesis and cutaneous permeability barrier functions induced by tumor necrosis factor-alpha and interferon-gamma in human epidermis
    • Hatano Y, Terashi H, Arakawa S, Katagiri K (2005) Interleukin-4 suppresses the enhancement of ceramide synthesis and cutaneous permeability barrier functions induced by tumor necrosis factor-alpha and interferon-gamma in human epidermis. J Invest Dermatol 124:786-92
    • (2005) J Invest Dermatol , vol.124 , pp. 786-792
    • Hatano, Y.1    Terashi, H.2    Arakawa, S.3    Katagiri, K.4
  • 18
    • 0033038503 scopus 로고    scopus 로고
    • Mass isotopomer distribution analysis at eight years: Theoretical, analytic, and experimental considerations
    • Hellerstein MK, Neese RA (1999) Mass isotopomer distribution analysis at eight years: theoretical, analytic, and experimental considerations. Am J Physiol 276(Part 1):E1146-70
    • (1999) Am J Physiol , vol.276 , Issue.1 PART
    • Hellerstein, M.K.1    Neese, R.A.2
  • 19
    • 0346363876 scopus 로고    scopus 로고
    • The organization of human epidermis: Functional epidermal units and phi proportionality
    • Hoath SB, Leahy DG (2003) The organization of human epidermis: functional epidermal units and phi proportionality. J Invest Dermatol 121:1440-6
    • (2003) J Invest Dermatol , vol.121 , pp. 1440-1446
    • Hoath, S.B.1    Leahy, D.G.2
  • 20
    • 3242888059 scopus 로고    scopus 로고
    • Dynamics of keratinocytes in vivo using HO labeling: A sensitive marker of epidermal proliferation state
    • Hsieh E, Chai CM, de Lumen BO, Neese RA, Hellerstein MK (2004) Dynamics of keratinocytes in vivo using HO labeling: a sensitive marker of epidermal proliferation state. J Invest Dermatol 123:530-6
    • (2004) J Invest Dermatol , vol.123 , pp. 530-536
    • Hsieh, E.1    Chai, C.M.2    De Lumen, B.O.3    Neese, R.A.4    Hellerstein, M.K.5
  • 21
    • 2442562327 scopus 로고    scopus 로고
    • Isolation of nuclei from label-retaining cells and measurement of their turnover rates in rat colon
    • Kim SJ, Cheung S, Hellerstein MK (2004) Isolation of nuclei from label-retaining cells and measurement of their turnover rates in rat colon. Am J Physiol Cell Physiol 286:C1464-73
    • (2004) Am J Physiol Cell Physiol , vol.286
    • Kim, S.J.1    Cheung, S.2    Hellerstein, M.K.3
  • 22
    • 0037275640 scopus 로고    scopus 로고
    • Keratins: A structural scaffold with emerging functions
    • Kirfel J, Magin TM, Reichelt J (2003) Keratins: a structural scaffold with emerging functions. Cell Mol Life Sci 60:56-71
    • (2003) Cell Mol Life Sci , vol.60 , pp. 56-71
    • Kirfel, J.1    Magin, T.M.2    Reichelt, J.3
  • 23
    • 4644309388 scopus 로고    scopus 로고
    • Evaluating psoriasis with psoriasis area and severity index, psoriasis global assessment, and lattice system physician's global assessment
    • Langley R, Ellis CN (2004) Evaluating psoriasis with psoriasis area and severity index, psoriasis global assessment, and lattice system physician's global assessment. J Am Acad Dermatol 51:563-9
    • (2004) J Am Acad Dermatol , vol.51 , pp. 563-569
    • Langley, R.1    Ellis, C.N.2
  • 24
    • 0037420518 scopus 로고    scopus 로고
    • Psoriasis
    • Lebwohl M (2003) Psoriasis. Lancet 361:1197-204
    • (2003) Lancet , vol.361 , pp. 1197-1204
    • Lebwohl, M.1
  • 25
    • 8344232534 scopus 로고    scopus 로고
    • Stratum corneum adhesive tape stripping: Influence of anatomical site, application pressure, duration and removal
    • Löffler H, Dreher F, Maibach HI (2004) Stratum corneum adhesive tape stripping: influence of anatomical site, application pressure, duration and removal. Br J Dermatol 151:746-52
    • (2004) Br J Dermatol , vol.151 , pp. 746-752
    • Löffler, H.1    Dreher, F.2    Maibach, H.I.3
  • 26
    • 8844270938 scopus 로고    scopus 로고
    • A Simplified Psoriasis Area Severity Index (SPASI) for rating psoriasis severity in clinic patients
    • Louden B, Pearce DJ, Lang W, Feldman SR (2004) A Simplified Psoriasis Area Severity Index (SPASI) for rating psoriasis severity in clinic patients. Dermatol Online J 10:7
    • (2004) Dermatol Online J , vol.10 , pp. 7
    • Louden, B.1    Pearce, D.J.2    Lang, W.3    Feldman, S.R.4
  • 28
    • 20044372326 scopus 로고    scopus 로고
    • In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells
    • Messmer BT, Messmer D, Allen SL, Kolitz JE, Kudalkar P, Cesar D et al. (2005) In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells. J Clin Invest 115:755-64
    • (2005) J Clin Invest , vol.115 , pp. 755-764
    • Messmer, B.T.1    Messmer, D.2    Allen, S.L.3    Kolitz, J.E.4    Kudalkar, P.5    Cesar, D.6
  • 29
    • 0000586992 scopus 로고
    • Sticky slides and tape techniques to harvest stratum corneum
    • (Serup J, Jemec GBE, eds), Boca Raton, FL: CRC Press, Chapter 7.2
    • Miller DL (1995) Sticky slides and tape techniques to harvest stratum corneum. In: Handbook of non-invasive methods and the skin (Serup J, Jemec GBE, eds), Boca Raton, FL: CRC Press, Chapter 7.2
    • (1995) Handbook of Non-invasive Methods and the Skin
    • Miller, D.L.1
  • 30
    • 18444391222 scopus 로고    scopus 로고
    • Development of a novel method for measuring in vivo breast epithelial cell proliferation in humans
    • Misell L, Hwang ES, Au A, Esserman L, Hellerstein MK (2005) Development of a novel method for measuring in vivo breast epithelial cell proliferation in humans. Breast Cancer Res Treat 89:257-64
    • (2005) Breast Cancer Res Treat , vol.89 , pp. 257-264
    • Misell, L.1    Hwang, E.S.2    Au, A.3    Esserman, L.4    Hellerstein, M.K.5
  • 33
    • 0035892726 scopus 로고    scopus 로고
    • Advances in the stable isotope-mass spectrometric measurement of DNA synthesis and cell proliferation
    • Neese RA, Siler SQ, Cesar D, Antelo F, Lee D, Misell L et al. (2001) Advances in the stable isotope-mass spectrometric measurement of DNA synthesis and cell proliferation. Anal Biochem 298:189-95
    • (2001) Anal Biochem , vol.298 , pp. 189-195
    • Neese, R.A.1    Siler, S.Q.2    Cesar, D.3    Antelo, F.4    Lee, D.5    Misell, L.6
  • 34
    • 3042845754 scopus 로고    scopus 로고
    • Recent insights into the immunopathogenesis of psoriasis provide new therapeutic opportunities
    • Nickoloff BJ, Nestle FO (2004) Recent insights into the immunopathogenesis of psoriasis provide new therapeutic opportunities. J Clin Invest 113:1664-75
    • (2004) J Clin Invest , vol.113 , pp. 1664-1675
    • Nickoloff, B.J.1    Nestle, F.O.2
  • 35
    • 0031982101 scopus 로고    scopus 로고
    • Lymphadenopathy, elevated serum IgE levels, autoimmunity, and mast cell accumulation in flaky skin mutant mice
    • Pelsue SC, Schweitzer PA, Schweitzer IB, Christianson SW, Gott B, Sundberg JP et al. (1998) Lymphadenopathy, elevated serum IgE levels, autoimmunity, and mast cell accumulation in flaky skin mutant mice. Eur J Immunol 28:1379-88
    • (1998) Eur J Immunol , vol.28 , pp. 1379-1388
    • Pelsue, S.C.1    Schweitzer, P.A.2    Schweitzer, I.B.3    Christianson, S.W.4    Gott, B.5    Sundberg, J.P.6
  • 36
    • 0021985475 scopus 로고
    • Skin surface stripping in diagnosing and monitoring inflammatory, xerotic, and neoplastic diseases
    • Pierard-Franchimont C, Pierard GE (1985) Skin surface stripping in diagnosing and monitoring inflammatory, xerotic, and neoplastic diseases. Pediatric Dermatol 2:180-4
    • (1985) Pediatric Dermatol , vol.2 , pp. 180-184
    • Pierard-Franchimont, C.1    Pierard, G.E.2
  • 37
    • 0001039866 scopus 로고
    • Glycine-C-14-incorporation into the proteins of normal stratum corneum and the abnormal stratum corneum of psoriasis
    • Rothberg S, Crounse RG, Lee JL (1961) Glycine-C-14-incorporation into the proteins of normal stratum corneum and the abnormal stratum corneum of psoriasis. J Invest Dermatol 37:497-505
    • (1961) J Invest Dermatol , vol.37 , pp. 497-505
    • Rothberg, S.1    Crounse, R.G.2    Lee, J.L.3
  • 39
    • 13444269249 scopus 로고    scopus 로고
    • Sta3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model
    • Sano S, Chan KS, Carbajal S, Clifford J, Peavey M, Kiguchi K et al. (2005) Sta3 links activated keratinocytes and immunocytes required for development of psoriasis in a novel transgenic mouse model. Nat Med 11:43-9
    • (2005) Nat Med , vol.11 , pp. 43-49
    • Sano, S.1    Chan, K.S.2    Carbajal, S.3    Clifford, J.4    Peavey, M.5    Kiguchi, K.6
  • 40
    • 0032908051 scopus 로고    scopus 로고
    • Animal models of psoriasis - What can we learn from them?
    • Schön MP (1999) Animal models of psoriasis - what can we learn from them? J Invest Dermatol 112:405-10
    • (1999) J Invest Dermatol , vol.112 , pp. 405-410
    • Schön, M.P.1
  • 42
    • 0025226174 scopus 로고
    • Inherited mouse mutations as models of human adnexal, cornification, and papulosquamous dermatoses
    • Sundberg JP, Beamer WG, Shultz LD, Dunstan RW (1990) Inherited mouse mutations as models of human adnexal, cornification, and papulosquamous dermatoses. J Invest Dermatol 95:62S-3S
    • (1990) J Invest Dermatol , vol.95
    • Sundberg, J.P.1    Beamer, W.G.2    Shultz, L.D.3    Dunstan, R.W.4
  • 44
    • 0030785132 scopus 로고    scopus 로고
    • Development and progression of psoriasiform dermatitis and systemic lesions in the flaky skin (fsn) mouse mutant
    • Sundberg JP, France M, Boggess D, Sundberg BA, Jenson AB, Beamer WG et al. (1997) Development and progression of psoriasiform dermatitis and systemic lesions in the flaky skin (fsn) mouse mutant. Pathobiology 65:271-86
    • (1997) Pathobiology , vol.65 , pp. 271-286
    • Sundberg, J.P.1    France, M.2    Boggess, D.3    Sundberg, B.A.4    Jenson, A.B.5    Beamer, W.G.6
  • 46
    • 0036683057 scopus 로고    scopus 로고
    • Role of integrins in regulating epidermal adhesion, growth and differentiation
    • Watt FM (2002) Role of integrins in regulating epidermal adhesion, growth and differentiation. EMBO J 21:3919-26
    • (2002) EMBO J , vol.21 , pp. 3919-3926
    • Watt, F.M.1
  • 50
    • 0038644624 scopus 로고    scopus 로고
    • Transgenic delivery of VEGF to mouse skin leads to an inflammatory condition resembling human psoriasis
    • Xia YP, Li B, Hylton D, Detmar M, Yancopoulos GD, Rudge JS (2003) Transgenic delivery of VEGF to mouse skin leads to an inflammatory condition resembling human psoriasis. Blood 102:161-8
    • (2003) Blood , vol.102 , pp. 161-168
    • Xia, Y.P.1    Li, B.2    Hylton, D.3    Detmar, M.4    Yancopoulos, G.D.5    Rudge, J.S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.