Comparison of topical glyceryl trinitrate ointment and oral nifedipine in the treatment of chronic anal fissure

Acta Chirurgica Belgica

Volumn 106, Issue 1, 2006, Pages 55-58

  Mustafa, Nadhim A ^a   Cengiz, S ^a   Turkyilmaz S ^a   Yucel Y ^a  

^a KARADENIZ TECHNICAL UNIVERSITY   (Turkey)

Author keywords

Anal fissure; Glyceryl trinitrate; Nifedipine

Indexed keywords

EID: 33645033947     PISSN: 00015458     EISSN: 25770160     Source Type: Journal    
DOI: 10.1080/00015458.2006.11679834     Document Type: Article

References (30)

1. KHUBCHANDAIL I. T., REED J. F. Sequelae of internal sphincterotomy for chronic fissure in -ano. Br J Surg, 1989, 76: 431-4.
2. GARCIA AGUILAR J., BELMONTE C., WONG W. D., LOWRY A. C., MADOFF R. D. Open vs. closed sphincterotomy for chronic anal fissure: long-term results. Dis Colon Rectum, 1996, 39: 440-3.
3. COOK T. A., BRADING A. F., MORTENSEN N. J. M. Differences in contractile properties of anorectal smooth muscle and the effect of calcium channel blockade. Br J Surg, 1999, 86: 70-5.
4. COOK T. A., BRADING A. F., MORTENSEN N. J. M. Effects of nifedipine on anorectal smooth muscle in vitro. Dis Colon Rectum, 1999, 42: 782-7.
5. MACLEOD S. R., EVANS J. Symptomatic care and nitroglycerin in the management of anal fissure. J Gastrointest, 2002, 6: 278-80.
6. CARAPETI E. A., KAMM M. A., EVANS B. K., PHILIPS R. Topical Diltiazem and bethanechol decrease anal sphincter pressure without side effects. Gut, 1999, 45: 719-22.
7. PITT J., DAXON P. M., HALLAN R. I., BOULOS P. B. A double-blind randomized placebo-controlled trial of oral indoramin to treat chronic anal fissure. Colorectal Disease, 2001, 3: 165-8.
8. MARIA G., CASSETTA E., GUL D., BRISINDA G., BENTIVOGGLO A. R. I. A comparison of botulinum toxin and saline for the treatment of chronic anal fissure. N Engl J Med, 1998, 338: 217-20.
9. BIRISINDA G., MARIA G., BENTIVAGLIO A. R., CASSETTE E., GUI D., ALBANASE A. A comparison of injection of botulinum toxin and topical nitroglycerin ointment for the treatment of chronic anal fissure. N Eng J Med, 1999, 341: 65-9.
10. ARGOV S., LEVENDOVSKY O. Open lateral sphincterotomy is still the best treatment for chronic anal fissure. Am J Surg, 2000, 179: 201-2.
11. PERNIKOFF B. J., EISENSTAT T. E., RUBIN R. J., OLIVER G. C., SELVATI E. P. Reappraisal of partial lateral internal sphincterotomy. Dis Colon Rectum, 1994, 37: 1291-5.
12. RICHARD C. S., GREGOIRE R., PLEWES E. A. Internal sphincterotomy is superior to topical nitroglycerin in the treatment of chronic anal fissure: results of a randomized, controlled trial by the Canadian Colorectal Surgical Trials Group. Dis Colon Rectum, 2000, 43: 1048-57.
13. JAMESON J. S., CHIA Y. W., KAMM M. A., SPEAKMAN C. T., CHYE Y. H., HENRY M. M. Effect of age, sex and parity on anorectal function. Br J Surg, 1994, 81: 1689-92.
14. O'KELLY T., BRADING A., MORTENSEN N. Nerve mediated relaxation of the human internal anal sphincter: the role of nitric oxide. Gut, 1993, 34: 689-93.
15. JONARD P., ESSAMRI B. Diltiazem and internal anal sphincter. Lancet, 1987, 1: 754.
16. LUND J. N., SCHOLEFIELD J. H. A prospective, randomized double blind, placebo-controlled trial of glyceryl trinitrate ointment treatment in anal fissure. Lancet, 1997, 349: 11-4.
17. KENNEDY M. L., SOWTER S., NGUYEN H., LUBOWSKI D. Z. Glyceryl trinitrate ointment for the treatment of chronic anal fissure: Results of a placebo-controlled trial and long term follow-up. Dis Colon Rectum, 1999, 42: 1000-6.
18. LODER P. B., KAMM M. A., NICHOLLS R. J., PHILIPS R. K. 'Reversible chemical sphincterotomy' by local application of glyceryl trinitrate. Br J Surg, 1994, 81: 1386-9.
19. GUILLEMOT F., LONE Y. C., LEROI H., LAMBLIN M. D., CORTOT A. Nitroglycerin in situ reduces upper anal canal pressure. Dig Dig Sci, 1992, 37: 155 (letter).
20. GUILLEMOT F., LEROI H., LONE Y. C., ROUSSEAU C. G., LAMBLIN M. D., CORTOT A. Action of in situ nitroglycerin on upper anal canal pressure of patients with terminal constipation. A pilot study. Dis Colon Rectum, 1993, 36: 372-6.
21. KNIGT J. S., BIRKS M., FAROUK R. Topical diltiazem ointment in the treatment of chronic anal fissure. Br J Surg, 2001, 88: 553-6.
22. CARAPETI E. A., KAMM M. A., PHILLIPS R. K. Topical diltiazem and bethanechol decrease anal sphincter pressure and heal anal fissure without side effects. Dis Colon Rectum, 2000, 43: 1359-62.
23. ANTROPOLI C., PERROTTI P., RUBINO M. Nifedipine for local use in conservative treatment of anal fissures: preliminary results of a multicenter study. Dis Colon Rectum, 1999, 42: 1011-5.
24. ALTOMARE D. F., RINALDI M., MILITO G. Glyceryl trinitrate for chronic anal fissure-healing or headache? Results of a multicenter, randomized, placebo-controlled, double-blind trial. Dis Colon Rectum, 2000, 43: 174-81.
25. BACHER H., MISCHINGER H. J., WERKGARTNER G. Local nitroglycerin for treatment of anal fissure: An alternative to lateral sphincterotomy?. Dis Colon Rectum, 1997, 40: 840-5.
26. CARAPETI E. A., KAMM M. A., MCDONALD P. J. Randomized controlled trial shows that glyceryl trinitrate heals anal fissures, higher doses are not more effective, and there is a high recurrence rate. Gut, 1999, 44: 727-30.
27. CARAPETI E. A., KAMM M. A., EVANS B. K., PHILLIPS R. K. S. Diltiazem lowers resting anal sphincter pressure: A potential low side-effect alternative to glyceryl trinitrate for fissures. Gut, 1998, 42: A97.
28. COOK T. A., HUMPHREYS M. M. F., MORTENSEN N. J. M. Oral nifedipine reduces resting anal pressure and heals chronic anal fissure. Br J Surg, 1999, 86: 1269-73.
29. KOCHER H. M., STEWARD M., LEATHER A. J. M., CULLEN P. T. Randomized clinical trial assessing the side-effect of glyceryl trinitrate and diltiazem hydrochloride in the treatment of chronic anal fissure. Br J Surg, 2002, 89: 413-7.
30. OETTLE G. J. Glycerly trinitrate vs. sphincterotomy for treatment of chronic fissure in-ano: a randomized, controlled trial. Dis Colon Rectum, 1997, 40: 1318-20.