Aza-retinoids as novel retinoid X receptor-specific agonists

Bioorganic and Medicinal Chemistry Letters

Volumn 16, Issue 9, 2006, Pages 2352-2356

  Farmer, Luc J ^a,b   Marron, Kristen S ^a   Canan Koch, Stacie S ^a,c   Hwang, C K ^a   Kallel, E Adam ^a   Zhi, Lin ^a   Nadzan, Alex M ^a   Robertson, Dave W ^a   Bennani, Youssef L ^a,b  

^a LIGAND PHARMACEUTICALS INC   (United States)

^b VERTEX PHARMACEUTICALS   (United States)

^c PFIZER INC   (United States)

Author keywords

RXR selective retinoids; RXR agonists

Indexed keywords

AZARETINOID DERIVATIVE; RETINOID DERIVATIVE; RETINOID X RECEPTOR AGONIST; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DOSE RESPONSE; DRUG CONFORMATION; DRUG POTENCY; DRUG STRUCTURE; DRUG SYNTHESIS; LIPOPHILICITY; STRUCTURE ACTIVITY RELATION;

AZA COMPOUNDS; MOLECULAR STRUCTURE; RETINOID X RECEPTORS; RETINOIDS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33644988190     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2005.12.003     Document Type: Article

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