Enantioselective syntheses of potent retinoid X receptor ligands: Differential biological activities of individual antipodes

Journal of Medicinal Chemistry

Volumn 44, Issue 14, 2001, Pages 2298-2303

  Vuligonda, V ^a   Thacher, S M ^a   Chandraratna, R A S ^a  

^a ALLERGAN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AGN 194204; AGN 194277; RETINOID; RETINOID X RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHIRALITY; CONTROLLED STUDY; DIASTEREOISOMER; ENANTIOMER; GENETIC TRANSCRIPTION; HYPOGLYCEMIA; LIGAND BINDING; MOUSE; NONHUMAN; RACEMIC MIXTURE; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TRANSACTIVATION;

ANIMALS; BACULOVIRIDAE; BINDING, COMPETITIVE; BLOOD GLUCOSE; CRYSTALLOGRAPHY, X-RAY; FATTY ACIDS, UNSATURATED; HYPOGLYCEMIC AGENTS; LIGANDS; MICE; MICE, MUTANT STRAINS; RADIOLIGAND ASSAY; RECEPTORS, RETINOIC ACID; RETINOID X RECEPTORS; STEREOISOMERISM; STRUCTURE-ACTIVITY RELATIONSHIP; TETRAHYDRONAPHTHALENES; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS;

EID: 0035811459     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm0100584     Document Type: Article

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