Design, synthesis and structure-activity relationship of novel RXR-selective modulators

Bioorganic and Medicinal Chemistry Letters

Volumn 14, Issue 6, 2004, Pages 1593-1598

  Michellys, Pierre Yves ^a,d   D'Arrigo, Jennifer ^a   Grese, Timothy A ^a,c   Karanewsky, Donald S ^a,d   Leibowitz, Mark D ^a   Mais, Dale A ^a   Mapes, Christopher M ^a,e   Reifel Miller, Anne ^a,c   Rungta, Deepa ^a   Boehm, Marcus F ^a,b  

^a LIGAND PHARMACEUTICALS INC   (United States)

^b BIOGEN   (United States)

^c ELI LILLY AND COMPANY   (United States)

^d GENOMICS INSTITUTE OF THE NOVARTIS RESEARCH FOUNDATION   (United States)

^e JOHNSON AND JOHNSON PHARMACEUTICAL RESEARCH AND DEVELOPMENT   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BENZOFURAN DERIVATIVE; BENZOTHIOPHENE DERIVATIVE; LIGAND;

ARTICLE; BINDING AFFINITY; DRUG ACTIVITY; DRUG DESIGN; DRUG EFFICACY; DRUG SCREENING; DRUG SELECTIVITY; DRUG SYNTHESIS; HYDROLYSIS; STRUCTURE ANALYSIS; SUBSTITUTION REACTION;

DRUG DESIGN; PROTEIN BINDING; RECEPTORS, RETINOIC ACID; RETINOID X RECEPTORS; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION FACTORS; TRETINOIN;

EID: 10744225472     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2003.12.089     Document Type: Article

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