Enhanced sympathetic control of renal function in rats congenic for the hypertension-related region on chromosome 1

Clinical and Experimental Pharmacology and Physiology

Volumn 32, Issue 12, 2005, Pages 1055-1060

  Wang, Tao ^a   Kobayashi, Yuta ^a   Nabika, Toru ^a   Takabatake, Toshikazu ^a  

^a SHIMANE UNIVERSITY   (Japan)

Author keywords

Congenic strain; Denervation; Kidney; Stroke prone spontaneously hypertensive rat; Tubuloglomerular feedback

Indexed keywords

NORADRENALIN;

ADRENERGIC SYSTEM; ANESTHESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CHROMOSOME 1; CHROMOSOME NOR; CONGENIC STRAIN; CONTROLLED STUDY; FEEDBACK SYSTEM; FLOW RATE; GLOMERULUS FILTRATION; HYPERTENSION; KIDNEY BLOOD FLOW; KIDNEY DENERVATION; KIDNEY FUNCTION; KIDNEY TUBULE FUNCTION; KIDNEY VASCULAR RESISTANCE; MALE; NONHUMAN; PERFUSION; QUANTITATIVE TRAIT LOCUS; RAT; RAT STRAIN; SODIUM EXCRETION; STATISTICAL SIGNIFICANCE; SYMPATHETIC TONE; URINARY EXCRETION; VASOCONSTRICTION; ANIMAL; BLOOD PRESSURE; CEREBROVASCULAR ACCIDENT; CHROMOSOME; DENERVATION; GENETICS; IN VITRO STUDY; INNERVATION; KIDNEY; KIDNEY FUNCTION TEST; KIDNEY PROXIMAL TUBULE; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; SPONTANEOUSLY HYPERTENSIVE RAT; WISTAR KYOTO RAT;

ANIMALS; BLOOD PRESSURE; CEREBROVASCULAR ACCIDENT; CHROMOSOMES; DENERVATION; FEEDBACK; HYPERTENSION; KIDNEY; KIDNEY FUNCTION TESTS; KIDNEY TUBULES, PROXIMAL; MALE; NOREPINEPHRINE; PERFUSION; RATS; RATS, INBRED SHR; RATS, INBRED WKY; SYMPATHETIC NERVOUS SYSTEM;

EID: 33644976227     PISSN: 03051870     EISSN: 14401681     Source Type: Journal    
DOI: 10.1111/j.1440-1681.2005.04304.x     Document Type: Article

References (27)

1. Nabika T Kobayashi Y Yamori Y. Congenic rats for hypertension: How useful are they for the hunting of hypertension genes? Clin. Exp. Pharmacol. Physiol. 2000 27 : 251 6.
2. Iwai N Tsujita Y Kinoshita M. Isolation of a chromosome 1 region that contributes to high blood pressure and salt sensitivity. Hypertension 1998 32 : 636 8.
3. Samani NJ Lodwick D Vincent M et al. A gene differentially expressed in the kidney of the spontaneously hypertensive rat cosegregates with increased blood pressure. J. Clin. Invest. 1993 92 : 1099 103.
4. Frantz SA Kaiser M Gardiner SM et al. Successful isolation of a rat chromosome 1 blood pressure quantitative trait locus in reciprocal congenic strains. Hypertension 1998 32 : 639 46.
5. Hubner N Lee YA Lindpaintner K Ganten D Kreutz R. Congenic substitution mapping excludes Sa as a candidate gene locus for a blood pressure quantitative trait locus on rat chromosome 1. Hypertension 1999 34 : 643 8.
6. St Lezin E Liu W Wang JM. Genetic analysis of rat chromosome 1 and the Sa gene in spontaneous hypertension. Hypertension 2000 35 : 225 30.
7. Rapp JP. Genetic analysis of the inherited hypertension in the rat. Physiol. Rev. 2000 80 : 135 72.
8. Folkow B. Physiological aspects of primary hypertension. Physiol. Rev. 1982 62 : 347 504.
9. Judy WV Watanabe AM Murphy WR Aprison BS Yu PL. Sympathetic nerve activity and blood pressure in normotensive backcross rats genetically related to the spontaneously hypertensive rat. Hypertension 1979 1 : 598 604.
10. Cui ZH Ikeda K Kawakami K Gonda T Nabika T Masuda J. Exaggerated response to restraint stress in rats congenic for the chromosome 1 blood pressure quantitative trait locus. Clin. Exp. Pharmacol. Physiol. 2003 30 : 464 9.
11. Cui ZH Ikeda K Kawakami K Gonda T Masuda J Nabika T. Exaggerated response to cold stress in a congenic strain for the quantitative trait locus for blood pressure. J. Hypertens. 2004 11 : 2103 9.
12. Grisk O Rettig R. Interactions between the sympathetic nervous system and the kidneys in arterial hypertension. Cardiovasc. Res. 2004 61 : 238 46.
13. Rettig R Schmitt B Pelzl B Speck T. The kidney and primary hypertension: Contributions from renal transplantation studies in animals and humans. J. Hypertens. 1993 11 : 883 91.
14. Takabatake T Ushiogi Y Ohta K Hattori N. Attenuation of enhanced tubuloglomerular feedback activity in SHR by renal denervation. Am. J. Physiol. 1990 258 : F980 5.
15. Schnermann J. Juxtaglomerular cell complex in the regulation of renal salt excretion. Am. J. Physiol. 1998 274 : R263 79.
16. Mashimo T Nabika T Matsumoto C et al. Aging and salt-loading modulate blood pressure QTLs in rats. Am. J. Hypertens. 1999 12 : 1098 104.
17. Takabatake T. Feedback regulation of glomerular filtration rate in the denervated rat kidney. Kidney Int. 1982 22 ( Suppl. 12 S129 35.
18. Hjemdahl P Daleskog M Kahan T. Determination of plasma catecholamines by high performance liquid chromatography with electrochemical detection: Comparison with a radioenzymatic method. Life Sci. 1979 25 : 131 8.
19. Lawry OH Rosenburg NJ Farr AL Randall RJ. Protein measurement with the folin phenol reagent. J. Biol. Chem. 1951 193 : 265 75.
20. Kobayashi Y Nabika T Cui Z-H Kawakami K Masuda J Gonda T. Vascular and serum noradrenaline in congenic rat strain for the hypertension related region on the chromosome 1. Clin. Exp. Hypertens. 2001 23 : 429.
21. Hall JE Brands MW. The renin-angiotensin-aldosterone systems: Renal mechanisms and circulatory homeostasis. In: Seldin DW, Giebisch G (eds). The Kidney: Physiology and Pathophysiology. Lippincott Williams & Wilkins, New York. 2000 Ch 0.
22. Gebremedhin D Fenoy FJ Harder DR Roman RJ. Enhanced vascular tone in the renal vasculature of spontaneously hypertensive rats. Hypertension 1990 16 : 648 54.
23. Grisk O Rose HJ Lorenz G Rettig R. Sympathetic-renal interaction in chronic arterial pressure control. Am. J. Physiol. Renal. Physiol. 2002 283 : R441 50.
24. 1-Adrenergic receptor blockade reduces afferent and efferent glomerular arteriolar resistances in SHR. Am. J. Physiol. 1991 261 : R576 80.
25. Rudd MA Grippo RS Arendshorst WJ. Acute renal denervation produces a diuresis and natriuresis in young SHR but not WKY rats. Am. J. Physiol. 1986 251 : F655 61.
26. Beach RE. Renal nerve-mediated proximal tubule solute reabsorption contributes to hypertension in spontaneously hypertensive rats. Clin. Exp. Hypertens. A 1992 14 : 685 97.
27. 2O transport in Henle's loop of the rat. Am. J. Physiol. 1982 243 : F576 80.