Design of a hyperstable protein by rational consideration of unfolded state interactions

Journal of the American Chemical Society

Volumn 128, Issue 10, 2006, Pages 3144-3145

  Anil, Burcu ^a   Craig Schapiro, Rebecca ^b   Raleigh, Daniel P ^a  

^a STONY BROOK UNIVERSITY   (United States)

^b WASHINGTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETIC ACID; ALANINE; GLYCINE; LYSINE; METHIONINE; RIBOSOME PROTEIN; RIBOSOME PROTEIN L9; SODIUM CHLORIDE; UNCLASSIFIED DRUG; UREA;

ALPHA HELIX; AMINO TERMINAL SEQUENCE; ARTICLE; BETA SHEET; BIOTECHNOLOGY; ENTROPY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN STABILITY; THERMOSTABILITY;

ALANINE; AMINO ACID SUBSTITUTION; CIRCULAR DICHROISM; GLYCINE; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN FOLDING; PROTEIN STRUCTURE, QUATERNARY; PROTEIN STRUCTURE, SECONDARY; RIBOSOMAL PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 33644965220     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja057874b     Document Type: Article

References (30)

1. (a) Chen, J.; Lu, Z.; Sakon, J.; Stiles, W. E. J. Mol. Biol. 2000, 303. 125-130 and references therein.
2. (b) Kumar, S.; Tsai, C. J.; Nussinov, R. Protein Eng. 2000, 13, 179-191.
3. (c) Lien, S.; Lowman, H. B. Trends Biotechnol. 2003, 21, 556-562.
4. (a) Schildbach, J. F.; Milla, M. E.; Jeffrey, P. D.; Raumann, B. E.; Sauer, R. T. Biochemists 1995, 34, 1405-1412.
5. (b) Malakauskas, S. M.; Mayo, S. L. Nat. Struct. Biol. 1998, 5, 470-475.
6. (c) Lehmann, M.; Wyss, M. Curr. Opin. Biotechnol. 2001, 12, 371-375.
7. (d) van den Burg, B.; Eijsink, V. G. Curr. Opin. Biotechnol. 2002, 13, 333-337.
8. (a) Lee, B.; Vasmatzis, G. Curr. Opin. Biotechnol. 1997, 4, 423-428.
9. (b) Pokkuluri, P. R.; Raffen, R.; Dieckman, L.; Boogaard, C.; Stevens, F. J.; Schiffer, M. Biophys. J. 2002, 82, 391-398.
10. (a) Shortle, D. FASEB J. 1996, 10, 27-34.
11. (b) Pace, C. N.; Alston, R. W.; Shaw, K. L. Protein Sci. 2000, 9, 1395-1398.
12. (c) Cho, J. H.; Raleigh, D. P. J. Mol. Biol. 2005, 353, 174-185.
13. Efimov, A. V. FEBS Lett. 1994, 355, 213-219.
14. (a) Kuhlman, B.; Boice, J. A.; Fairman, R.; Raleigh, D. P. Biochemistry 1998, 37, 1025-1032.
15. (b) Kuhlman, B.; Luisi, D. L.; Evans, P. A.; Raleigh, D. P. J. Mol. Biol. 1998, 284, 1661-1670.
16. (c) Luisi, D. L.; Raleigh, D. P. J. Mol. Biol. 2000, 299, 1091-1100.
17. (a) Kuhlman, B.; Luisi, D. L.; Young, P.; Raleigh, D. P. Biochemistry 1999, 38, 4896-4903.
18. (b) Luisi, D. L.; Wu, W. J.; Raleigh, D. P. J. Mol. Biol. 1999, 287, 395-407.
19. (a) Whitten, S. T.; Garcia-Moreno, E. B. Biochemistry 2000, 39, 14292-14304.
20. (b) Paci, E.; Vendruscolo, M.; Karplus, M. Proteins: Struct., Funct., Genet. 2002, 47, 379-392.
21. Cho, J. H.; Sato, S.; Raleigh. D. P. J. Mol. Biol. 2004, 338, 827-837.
22. (a) Matthews, B. W.; Nicholson, H.; Becktel, W. J. Proc. Natl. Acad. Sci. U.S.A. 1987, 84, 6663-6667.
23. (b) Ganter, C.; Plückthun, A. Biochemistry 1990, 29, 9395-9402.
24. (c) Stiles, W. E.; Pranata, J. Proteins 1995, 22, 132-140.
25. (a) Stiles, W. E.; Meeker, A. K.; Shortle, D. J. Mol. Biol. 1994, 235, 27-32.
26. (b) Takano, K.; Yamagala, Y.; Yulani, K. Proteins 2001, 45, 274-280.
27. (c) Kim, J.; Brych, S. R.; Lee, J.; Logan, T. M.; Blaber, M. J. Mol. Biol. 2003, 328, 951-961.
28. Anil, B.; Song, B.; Tang, Y.; Raleigh, D. P. J. Am. Chem. Soc. 2004, 126, 13194-13195.
29. Kraulis, P. J. J. Appl. Crystallogr. 1991, 24, 946-950.
30. Wulhrich, K. NMR of Proteins and Nucleic Acids; John Wiley and Sons: New York, 1986.