Type 2 diabetic rats are sensitive to thioacetamide hepatotoxicity

Toxicology and Applied Pharmacology

Volumn 211, Issue 3, 2006, Pages 221-232

  Sawant, Sharmilee P ^a   Dnyanmote, Ankur V ^a   Warbritton, Alan ^b   Latendresse, John R ^b   Mehendale, Harihara M ^a  

^a UNIVERSITY OF LOUISIANA AT MONROE   (United States)

^b NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

Author keywords

CCl4; Liver injury; Thioacetamide; Tissue repair; Type 2 diabetes

Indexed keywords

ALANINE; ASPARTATE AMINOTRANSFERASE; CYTOCHROME P450 2E1; INSULIN; THIOACETAMIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL CYCLE S PHASE; CELL DIVISION; CONTROLLED STUDY; COVALENT BOND; DETERIORATION; DISEASE COURSE; DISEASE PREDISPOSITION; DNA SYNTHESIS; HISTOPATHOLOGY; IMMUNOCHEMISTRY; INSULIN BLOOD LEVEL; LABELING INDEX; LETHALITY; LIVER FAILURE; LIVER INJURY; LIVER NECROSIS; LIVER TOXICITY; MALE; MORTALITY; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; RAT; SURVIVAL; TISSUE REPAIR;

ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DISEASE SUSCEPTIBILITY; HEPATITIS, TOXIC; IMMUNOHISTOCHEMISTRY; LIVER; MALE; PROLIFERATING CELL NUCLEAR ANTIGEN; RATS; RATS, SPRAGUE-DAWLEY; THIOACETAMIDE;

ANIMALIA;

EID: 33644950000     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2005.07.019     Document Type: Article

References (61)

1. J.H. Albrecht, and L.K. Hansen Cyclin D1 promotes mitogen-independent cell cycle progression in hepatocytes Cell Growth Differ. 10 1999 397 404
2. Y. Aniya, Y. Ojiri, R. Sunagawa, K. Murakami, G. Zhenzhong, G. Mimura, and M. Sakanashi Glutathione S-transferases and chloroform toxicity in streptozotocin-induced diabetic rats Jpn. J. Pharmacol. 50 1989 263 269
3. A.A. Aznar, C.T. Sanchez, R.M.L. Bentura, A.A. Lopez, and P.L. Diaz Effect of alloxan-induced diabetes on hepatic regeneration Rev. Esp. Enferm. Dig. 79 1991 313 319
4. R. Barra, and J.C. Hall Liver regeneration in normal and alloxan-induced diabetic rats J. Exp. Zool. 201 1977 93 99
5. N. Begum, and L. Ragolia High glucose and insulin inhibit VSMC MKP-1 expression by blocking iNOS via p38 MAPK activation Am. J. Physiol.: Cell Physiol. 278 2000 C81 C91
6. M. Brownlee Lilly lecture 1993. Glycation and diabetic complications Diabetes 43 1993 836 841
7. R. Bucala, P. Model, and A. Cerami Modification of DNA by reducing sugars: a possible mechanism for nucleic acid aging and age-related dysfunction in gene expression Proc. Natl. Acad. Sci. 81 1984 105 109
8. K. Burton A study of the conditions and mechanism of the diphenylamine reaction for the colorimetric estimation of deoxyribonucleic acid Biochem. J. 62 1956 315 323
9. A. Cerami, H. Vlassara, and M. Brownlee Glucose and aging Sci. Am. 256 1987 90 96
10. S. Chanda, and H.M. Mehendale Nutritional impact on the final outcome of injury inflicted by model hepatotoxicants: effect of glucose loading FASEB J. 9 1995 240 245
11. L.O. Chang, and W.B. Looney A biochemical and autoradiographic study of the in vivo utilization of tritiated thymidine in regenerating rat liver Cancer Res. 25 1965 1817 1822
12. J. Chauveau, Y. Moule, and C. Rouiller Isolation of pure and unaltered liver nuclei morphology and biochemical composition Exp. Cell Res. 11 1956 317 321
13. J. Chilakapati, M.C. Korrapati, and H.M. Mehendale Role of toxicokinetics of thioacetamide: role in initiation of liver injury Drug Metab. Dispos. 33 2005 1877 1885
14. J.F.L. Childs, and E.A. Siegler Compounds for control of orange decays Science 102 1945 68
15. S. Chin, S. Ramirez, L.E. Greenbaum, A. Naji, and R. Taub Blunting of the immediate-early gene and mitogenic response in hepatectomized type 1 diabetic animals Am. J. Physiol. 269 1995 E691 E700
16. O.F. Dajani, M. Refsnes, T.K. Guren, R.S. Horn, G.H. Thoresen, and T. Christoffersen Elevated glucose concentrations inhibit DNA synthesis and expression of c-myc in cultured hepatocytes Biochem. Biophys. Res. Commun. 202 1994 1476 1482
17. 1 to S phase clearance via cyclin signaling in the impaired liver tissue repair in thioacetamide-treated type 1 diabetic rats Toxicol. Appl. Pharmacol. 207 2005 89 102
18. S.S. Devi, and H.M. Mehendale The role of NF-κB signaling in impaired tissue repair in thioacetamide-treated type 1 diabetic rats Eur. J. Pharmacol. 523 2005 127 136
19. A.M. El-Hawari, and G.L. Plaa Potentiation of thioacetamide-induced hepatotoxicity in alloxan- and streptozotocin-diabetic rats Toxicol. Lett. 17 1983 293 300
20. H.B. El-Serag, and J.E. Everhart Diabetes increases the risk of acute hepatic failure Gastroenterology 122 2002 1822 1828
21. H.B. El-Serag, T. Tran, and J.E. Everhart Diabetes increases the risk of chronic liver disease and hepatocellular carcinoma Gastroenterology 126 2004 460 468
22. O.G.N. Fitzhugh, and A. Arthur Liver tumors in rats fed thiourea or thioacetamide Science 108 1948 626 628
23. B.I. Gaynes, and J.B. Watkins III Carbon tetrachloride and the sorbitol pathway in the diabetic mouse Comp. Biochem. Physiol., B 94 1989 213 217
24. M.H. Grant, and S.J. Duthie The cytotoxicity of menadione in hepatocytes isolated from streptozotocin-induced diabetic rats Biochem. Pharmacol. 37 1988 3793 3796
25. A. Greenwell, J.F. Foley, and R.R. Maronpot An enhancement method for immunohistochemical staining of proliferating cell nuclear antigen in archival rodent tissues Cancer Lett. 59 1991 251 256
26. G.K. Hanasono, M.G. Cote, and G.L. Plaa Potentiation of carbon tetrachloride-induced hepatotoxicity in alloxan- or streptozotocin-diabetic rats J. Pharmacol. Exp. Ther. 192 1975 592 604
27. G.K. Hanasono, H. Witschi, and G.L. Plaa Potentiation of the hepatotoxic responses to chemicals in alloxan-diabetic rats Proc. Soc. Exp. Biol. Med. 149 1975 903 907
28. P.M. Harrison, R.D. Hughes, A. Forbes, B. Portmann, G.J. Alexander, and R. Williams Failure of insulin and glucagon infusion to stimulate liver regeneration in fulminant hepatic failure J. Hepatol. 10 1990 332 336
29. M. Holecek, J. Simek, V. Palicka, and Z. Zadak Effect of glucose and branched chain amino acid (BCAA) infusion on onset of liver regeneration and plasma amino acid pattern in partially hepatectomized rats J. Hepatol. 13 1991 14 20
30. C. Huerta, S.Z. Zhao, and L.A. Garcia Rodriguez Risk of acute liver injury in patients with diabetes Pharmacotherapy 22 2002 1091 1096
31. M. Igarashi, H. Wakasaki, N. Takahara, H. Ishii, Z.Y. Jiang, T. Yamauchi, K. Kuboki, M. Meier, C.J. Rhodes, and G.L. King Glucose or diabetes activates p38 mitogen-activated protein kinase via different pathways J. Clin. Invest. 103 1999 185 195
32. J.N. Lavoie, G. L'Allemain, A. Brunet, R. Muller, and J. Pouyssegur Cyclin D1 expression is regulated positively by the p42/p44MAPK and negatively by the p38/HOGMAPK pathway J. Biol. Chem. 271 1999 20608 20616
33. I.A. Leclercq, J. Field, and G.C. Farrell Leptin-specific mechanisms for impaired liver regeneration in ob/ob mice after toxic injury Gastroenterology 124 2003 1451 1464
34. P.B. Limaye, U.M. Apte, K. Shankar, T.J. Bucci, A. Warbritton, and H.M. Mehendale Calpain released from dying hepatocytes mediates progression of acute liver injury induced by model hepatotoxicants Toxicol. Appl. Pharmacol. 191 2003 211 226
35. M. Lorenzi, E. Cagliero, and S. Toledo Glucose toxicity for human endothelial cells in culture. Delayed replication, disturbed cell cycle, and accelerated death Diabetes 34 1985 621 627
36. D.H. Mak, and K.M. Ko Alterations in susceptibility to carbon tetrachloride toxicity and hepatic antioxidant/detoxification system in streptozotocin-induced short-term diabetic rats: effects of insulin and Schisandrin B treatment Mol. Cell. Biochem. 175 1997 225 232
37. R.S. Mangipudy, and H.M. Mehendale Temporal changes in tissue repair upon repeated exposure to thioacetamide Toxicol. Appl. Pharmacol. 149 1998 254 257
38. R.S. Mangipudy, S. Chanda, and H.M. Mehendale Tissue repair response as a function of dose in thioacetamide hepatotoxicity Environ. Health Perspect. 103 1995 260 267
39. R.S. Mangipudy, P.S. Rao, and H.M. Mehendale Effect of an antimitotic agent colchicine on thioacetamide hepatotoxicity Environ. Health Perspect. 104 1996 744 749
40. T. Matsumoto, M. Yamaguchi, M. Kuzume, A. Matsumiya, H. Nakano, Y. Sanada, and K. Kumada Insulin gene transfer improves posthepatectomized status of diabetic rats Transplant. Proc. 32 2000 2378 2379
41. H.M. Mehendale Tissue repair: an important determinant of final outcome of toxicant-induced injury Toxicol. Pathol. 33 2005 41 51
42. H.M. Mehendale, and P.B. Limaye Calpain: a death protein that mediates progression of liver injury Trends Pharmacol. Sci. 26 2005 232 236
43. K. Ozawa, T. Yamada, M. Ukikusa, K. Ngala, T. Ida, A. Nakase, and T. Tobe Mitochondrial phosphorylative activity and DNA synthesis in regenerating liver of diabetic rats J. Surg. Res. 31 1981 38 45
44. W.R. Porter, and R.A. Neal Metabolism of thioacetamide and thioacetamide S-oxide by rat liver microsomes Drug Metab. Dispos. 6 1978 379 388
45. W.R. Porter, M.J. Gudzinowicz, and R.A. Neal Thioacetamide-induced hepatic necrosis: II. Pharmacokinetics of thioacetamide and thioacetamide-S- oxide in the rat J. Pharmacol. Exp. Ther. 208 1979 386 391
46. V.F. Price, and D.J. Jollow Increased resistance of diabetic rats to acetaminophen-induced hepatotoxicity J. Pharmacol. Exp. Ther. 220 1982 504 513
47. S.K. Ramaiah, U. Apte, and H.M. Mehendale Cytochrome P4502E1 induction increases thioacetamide liver injury in diet-restricted rats Drug Metab. Dispos. 29 2001 1088 1095
48. P.S. Rao, B.D. Lyn-Cook, N.A. Littlefield, and H.M. Mehendale High glucose alters cell proliferation dynamics in human hepatoma cells Int. J. Toxicol. 18 1999 297 306
49. S. Rojas, R. Rojas, L. Lamperti, P. Casanello, and L. Sobrevia Hyperglycaemia inhibits thymidine incorporation and cell growth via protein kinase C, mitogen-activated protein kinases and nitric oxide in human umbilical vein endothelium Exp. Physiol. 88 2003 209 219
50. S.P. Sawant, A.V. Dnyanmote, K. Shankar, P.B. Limaye, J.R. Latendresse, and H.M. Mehendale Potentiation of carbon tetrachloride hepatotoxicity and lethality in type 2 diabetic rats J. Pharmacol. Exp. Ther. 308 2004 694 704
51. S.P. Sawant, A.V. Dnyanmote, J.R. Latendresse, A. Warbritton, and H.M. Mehendale Molecular mechanisms of inhibited compensatory liver repair upon hepatotoxic challenge of type 2 diabetic rats The Toxicologist 84 2005 390
52. T.E. Starzl, A. Francavilla, C.G. Halgrimson, F.R. Francavilla, K.A. Porter, T.H. Brown, and C.W. Putnam The origin, hormonal nature, and action of hepatotrophic substances in portal venous blood Surg. Gynecol. Obstet. 137 1973 179 199
53. P. Stralfors Insulin second messengers BioEssays 19 1997 327 335
54. S. Swamy-Mruthinti, S.M. Shaw, H.R. Zhao, K. Green, and E.C. Abraham Evidence of a glycemic threshold for the development of cataracts in diabetic rats Curr. Eye Res. 18 1999 423 429
55. M. Torbenson, S.Q. Yang, H.Z. Liu, J. Huang, W. Gage, and A.M. Diehl STAT-3 overexpression and p21 up-regulation accompany impaired regeneration of fatty livers Am. J. Pathol. 161 2002 155 161
56. T. Wang, R.D. Fontenot, M.G. Soni, T.J. Bucci, and H.M. Mehendale Enhanced hepatotoxicity and toxic outcome of thioacetamide in streptozotocin-induced diabetic rats Toxicol. Appl. Pharmacol. 166 2000 92 100
57. T. Wang, K. Shankar, M.J. Ronis, and H.M. Mehendale Potentiation of thioacetamide liver injury in diabetic rats is due to induced CYP2E1 J. Pharmacol. Exp. Ther. 294 2000 473 479
58. T. Wang, K. Shankar, T.J. Bucci, A. Warbritton, and H.M. Mehendale Diallyl sulfide inhibition of CYP2E1 does not rescue diabetic rats from thioacetamide-induced mortality Toxicol. Appl. Pharmacol. 173 2001 27 37
59. C.H. Wang, Y.J. Chen, T.H. Lee, Y.S. Chen, B. Jawan, K.S. Hung, C.N. Lu, and J.K. Liu Protective effect of MDL28170 against thioacetamide-induced acute liver failure in mice J. Biomed. Sci. 11 2004 571 578
60. J.B. Watkins III, R.A. Sanders, and L.V. Beck The effect of long-term streptozotocin-induced diabetes on the hepatotoxicity of bromobenzene and carbon tetrachloride and hepatic biotransformation in rats Toxicol. Appl. Pharmacol. 93 1988 329 338
61. Y. Yamada, I. Kirillova, J.J. Peschon, and N. Fausto Initiation of liver growth by tumor necrosis factor: deficient liver regeneration in mice lacking type I tumor necrosis factor receptor Proc. Natl. Acad. Sci. 94 1997 1441 1446