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Volumn 43, Issue 11, 2006, Pages 1855-1863

Biological and molecular docking studies on coagulin-H: Human IL-2 novel natural inhibitor

Author keywords

Coagulin H; IL 2R; Immunosuppression; Interleukin 2; Withania coagulans; Withanolide

Indexed keywords

COAGULIN H; INTERLEUKIN 2; PREDNISOLONE; UNCLASSIFIED DRUG; WITHANOLIDE;

EID: 33644936754     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2005.10.020     Document Type: Article
Times cited : (55)

References (52)
  • 1
    • 0032788630 scopus 로고    scopus 로고
    • Studies on immunomodulatory activity of Withania somnifera (Ashwagandha) extracts in experimental immune inflammation
    • R. Agarwal, S. Diwanay, P. Patki, and B. Patwardhan Studies on immunomodulatory activity of Withania somnifera (Ashwagandha) extracts in experimental immune inflammation J. Ethnopharmacol. 67 1999 27 35
    • (1999) J. Ethnopharmacol. , vol.67 , pp. 27-35
    • Agarwal, R.1    Diwanay, S.2    Patki, P.3    Patwardhan, B.4
  • 2
    • 0025728741 scopus 로고
    • Effect of certain adaptogenic plant extract on drug-induced narcosis in female and male mice
    • F. Ahumada, M.A. Trincado, J.A. Arellano, J. Hancke, and G. Wikman Effect of certain adaptogenic plant extract on drug-induced narcosis in female and male mice Phytother. Res. 5 1991 29 31
    • (1991) Phytother. Res. , vol.5 , pp. 29-31
    • Ahumada, F.1    Trincado, M.A.2    Arellano, J.A.3    Hancke, J.4    Wikman, G.5
  • 3
  • 4
    • 0035136379 scopus 로고    scopus 로고
    • Screening of Yemeni medicinal plants for antibacterial and cytotoxic activities
    • N.A. Ali, W.D. Julich, C. Kusnick, and U. Lindequist Screening of Yemeni medicinal plants for antibacterial and cytotoxic activities J. Ethnopharmacol. 74 2001 173 179
    • (2001) J. Ethnopharmacol. , vol.74 , pp. 173-179
    • Ali, N.A.1    Julich, W.D.2    Kusnick, C.3    Lindequist, U.4
  • 5
    • 0037452709 scopus 로고    scopus 로고
    • Binding of small molecules to an adaptive protein-protein interface, Note: IUPAC Name of acyl phenyl alanine derivative [methyl (2S)-2-[(2-{3R)-1- [amino(imino)methyl]piperidinyl}acetyl)amino]-3-[4-(2-phenylethynyl)phenyl] propanoate] has been generated using Chem office ver. 6.0
    • Arkin, M.R., Randal, M., DeLano, W.L., Hyde, J., Luong, T.N., Oslob, J.D., Raphael, D.R., Taylor, L., Wang, J., McDowell, R.S., Wells, J.A., Braisted, A.C., 2003. Binding of small molecules to an adaptive protein-protein interface, Note: IUPAC Name of acyl phenyl alanine derivative [methyl (2S)-2-[(2-{3R)-1-[amino(imino)methyl]piperidinyl}acetyl)amino] -3-[4-(2-phenylethynyl)phenyl]propanoate] has been generated using Chem office ver. 6.0. Proc. Natl. Acad. Sci. 100, 1603-1608.
    • (2003) Proc. Natl. Acad. Sci. , vol.100 , pp. 1603-1608
    • Arkin, M.R.1    Randal, M.2    Delano, W.L.3    Hyde, J.4    Luong, T.N.5    Oslob, J.D.6    Raphael, D.R.7    Taylor, L.8    Wang, J.9    McDowell, R.S.10    Wells, J.A.11    Braisted, A.C.12
  • 8
    • 3042524904 scopus 로고
    • A well-behaved electrostatic potential based method using charge restraints for deriving atomic charges: The RESP model
    • C. Bayly, P. Cieplak, W. Cornell, and P. Kollman A well-behaved electrostatic potential based method using charge restraints for deriving atomic charges: the RESP model J. Phys. Chem. 97 1993 10269 10280
    • (1993) J. Phys. Chem. , vol.97 , pp. 10269-10280
    • Bayly, C.1    Cieplak, P.2    Cornell, W.3    Kollman, P.4
  • 9
    • 0026763387 scopus 로고
    • Unraveling the structure of IL-2
    • J.F. Bazan Unraveling the structure of IL-2 Science 257 1992 410 413
    • (1992) Science , vol.257 , pp. 410-413
    • Bazan, J.F.1
  • 10
    • 0033574397 scopus 로고    scopus 로고
    • The discovery of steroids and other novel FKBP inhibitors using a molecular docking program
    • P. Burkhard, U. Hommel, M. Sanner, and M.D. Walkinshaw The discovery of steroids and other novel FKBP inhibitors using a molecular docking program J. Mol. Biol. 287 1999 853 858
    • (1999) J. Mol. Biol. , vol.287 , pp. 853-858
    • Burkhard, P.1    Hommel, U.2    Sanner, M.3    Walkinshaw, M.D.4
  • 11
    • 0023790658 scopus 로고
    • Autocrine regulation of T-lymphocyte proliferation: Differential induction of IL-2 and IL-2 receptor
    • D.A. Cantrell, M.K. Collins, and M.J. Crumpton Autocrine regulation of T-lymphocyte proliferation: differential induction of IL-2 and IL-2 receptor Immunology 65 1988 343 349
    • (1988) Immunology , vol.65 , pp. 343-349
    • Cantrell, D.A.1    Collins, M.K.2    Crumpton, M.J.3
  • 13
    • 0020629928 scopus 로고
    • Induction of phenotypic differentiation, interleukin 2 production, and PHA responsiveness of "immature" human thymocytes by interleukin 1 and phorbol ester
    • J.E. de Vries, F.A. Vyth-Dreese, C.G. Figdor, H. Spits, J.M. Leemans, and W.S. Bont Induction of phenotypic differentiation, interleukin 2 production, and PHA responsiveness of "immature" human thymocytes by interleukin 1 and phorbol ester J. Immunol. 131 1983 201 206
    • (1983) J. Immunol. , vol.131 , pp. 201-206
    • De Vries, J.E.1    Vyth-Dreese, F.A.2    Figdor, C.G.3    Spits, H.4    Leemans, J.M.5    Bont, W.S.6
  • 16
    • 0025135112 scopus 로고
    • Automated docking of substrates to proteins by simulated annealing
    • D.S. Goodsell, and A.J. Olson Automated docking of substrates to proteins by simulated annealing Protein 1990 195 202
    • (1990) Protein , pp. 195-202
    • Goodsell, D.S.1    Olson, A.J.2
  • 17
    • 0345601897 scopus 로고    scopus 로고
    • Withania somnifera (Ashwagandha) attenuates antioxidant defense in aged spinal cord and inhibits copper induced lipid peroxidation and protein oxidative modifications
    • S.K. Gupta, A. Dua, and B.P. Vohra Withania somnifera (Ashwagandha) attenuates antioxidant defense in aged spinal cord and inhibits copper induced lipid peroxidation and protein oxidative modifications Drug Metabol. Drug Interact. 19 2003 211 222
    • (2003) Drug Metabol. Drug Interact. , vol.19 , pp. 211-222
    • Gupta, S.K.1    Dua, A.2    Vohra, B.P.3
  • 18
  • 20
    • 0028986560 scopus 로고
    • Differential inhibition of lymphokine-activated killing, proliferation, and cytokine secretion by humanized antibodies against the low- and intermediate-affinity interleukin-2 receptors. a novel model for activation of human peripheral blood mononuclear cells by interleukin 2
    • K.M. Heaton, and E.A. Grimm Differential inhibition of lymphokine-activated killing, proliferation, and cytokine secretion by humanized antibodies against the low- and intermediate-affinity interleukin-2 receptors. A novel model for activation of human peripheral blood mononuclear cells by interleukin 2 Hum. Immunol. 42 1995 274 280
    • (1995) Hum. Immunol. , vol.42 , pp. 274-280
    • Heaton, K.M.1    Grimm, E.A.2
  • 21
    • 0027245684 scopus 로고
    • Human interleukin 2 analogues that preferentially bind the intermediate-affinity interleukin 2 receptor lead to reduced secondary cytokine secretion: Implications for the use of these interleukin 2 analogues in cancer immunotherapy
    • K.M. Heaton, G. Ju, and E.A. Grimm Human interleukin 2 analogues that preferentially bind the intermediate-affinity interleukin 2 receptor lead to reduced secondary cytokine secretion: implications for the use of these interleukin 2 analogues in cancer immunotherapy Cancer Res. 53 1993 2597 2602
    • (1993) Cancer Res. , vol.53 , pp. 2597-2602
    • Heaton, K.M.1    Ju, G.2    Grimm, E.A.3
  • 22
    • 0027480380 scopus 로고
    • Characterization of lymphokine-activated killing by human peripheral blood mononuclear cells stimulated with interleukin 2 (IL-2) analogs specific for the intermediate affinity IL-2 receptor
    • K.M. Heaton, G. Ju, D.K. Morris, K. Delisio, P. Bailon, and E.A. Grimm Characterization of lymphokine-activated killing by human peripheral blood mononuclear cells stimulated with interleukin 2 (IL-2) analogs specific for the intermediate affinity IL-2 receptor Cell. Immunol. 147 1993 167 179
    • (1993) Cell. Immunol. , vol.147 , pp. 167-179
    • Heaton, K.M.1    Ju, G.2    Morris, D.K.3    Delisio, K.4    Bailon, P.5    Grimm, E.A.6
  • 23
    • 0026663806 scopus 로고
    • IL-2 responsiveness of lectin-induced lymphoblasts: Soluble IL-2 receptor release and differential in vitro effects of immunosuppressants
    • N. Hornung, J. Raskova, J. Raska, and D. Degiannis IL-2 responsiveness of lectin-induced lymphoblasts: soluble IL-2 receptor release and differential in vitro effects of immunosuppressants Int. J. Immunopharmacol. 14 1992 753 760
    • (1992) Int. J. Immunopharmacol. , vol.14 , pp. 753-760
    • Hornung, N.1    Raskova, J.2    Raska, J.3    Degiannis, D.4
  • 24
    • 0028473075 scopus 로고
    • Regulation of the human interleukin-2/interleukin-2 receptor system: A role for immunosuppression
    • R. Kaempfer Regulation of the human interleukin-2/interleukin-2 receptor system: a role for immunosuppression Proc. Soc. Exp. Biol. Med. 206 1994 176 180
    • (1994) Proc. Soc. Exp. Biol. Med. , vol.206 , pp. 176-180
    • Kaempfer, R.1
  • 26
    • 0034284355 scopus 로고    scopus 로고
    • Molecular mechanisms and Th1/Th2 pathways in corticosteroid of cytokine production
    • D. Kovalovsky, D. Refojo, F. Holsboer, and E. Arzt Molecular mechanisms and Th1/Th2 pathways in corticosteroid of cytokine production J. Neuroimmunol. 109 2000 23 29
    • (2000) J. Neuroimmunol. , vol.109 , pp. 23-29
    • Kovalovsky, D.1    Refojo, D.2    Holsboer, F.3    Arzt, E.4
  • 27
    • 1642344588 scopus 로고    scopus 로고
    • Effect of Withania somnifera on B16F-10 melanoma induced metastasis in mice
    • P.V. Leyon, and G. Kuttan Effect of Withania somnifera on B16F-10 melanoma induced metastasis in mice Phytother. Res. 18 2004 118 122
    • (2004) Phytother. Res. , vol.18 , pp. 118-122
    • Leyon, P.V.1    Kuttan, G.2
  • 28
    • 2942562539 scopus 로고    scopus 로고
    • Cyclosporine, tacrolimus, and mycophenolate mofetil in the treatment of inflammatory bowel disease
    • C.G. Loftus, L.J. Egan, and W.J. Sandborn Cyclosporine, tacrolimus, and mycophenolate mofetil in the treatment of inflammatory bowel disease Gastroenterol. Clin. North Am. 33 2004 141 169
    • (2004) Gastroenterol. Clin. North Am. , vol.33 , pp. 141-169
    • Loftus, C.G.1    Egan, L.J.2    Sandborn, W.J.3
  • 30
    • 2342663668 scopus 로고    scopus 로고
    • In vivo anti-inflammatory activity of Alchornea cordifolia (Schumach. & Thonn.) Mull. Arg. (Euphorbiaceae)
    • H.M. Manga, D. Brkic, D.E. Marie, and J. Quetin-Leclercq In vivo anti-inflammatory activity of Alchornea cordifolia (Schumach. & Thonn.) Mull. Arg. (Euphorbiaceae) J. Ethnopharmacol. 92 2004 209 214
    • (2004) J. Ethnopharmacol. , vol.92 , pp. 209-214
    • Manga, H.M.1    Brkic, D.2    Marie, D.E.3    Quetin-Leclercq, J.4
  • 31
    • 0026332547 scopus 로고
    • Electrostatic effects in proteins: Comparison of dielectric and charge models
    • E.L. Mehler, and T. Solmjer Electrostatic effects in proteins: comparison of dielectric and charge models Prot. Eng. 1991 903 910
    • (1991) Prot. Eng. , pp. 903-910
    • Mehler, E.L.1    Solmjer, T.2
  • 32
    • 0030203710 scopus 로고    scopus 로고
    • Distributed automated docking of flexible ligands to proteins: Parallel applications of AutoDock 2.4
    • G.M. Morris, D.S. Goodsell, R. Huey, and A.J. Olson Distributed automated docking of flexible ligands to proteins: parallel applications of AutoDock 2.4 J. Comp.-Aided Mol. Des. 1996 293 304
    • (1996) J. Comp.-Aided Mol. Des. , pp. 293-304
    • Morris, G.M.1    Goodsell, D.S.2    Huey, R.3    Olson, A.J.4
  • 34
    • 0028305712 scopus 로고
    • Novel mechanism of glucocorticoid-mediated gene repression: NF-KB is a target for glucocorticoid-mediated IL-8 gene repression
    • N. Mukaida, M. Morita, Y. Ishikawa, N. Rice, S. Okamoto, T. Kasahara, and K. Matsushima Novel mechanism of glucocorticoid-mediated gene repression: NF-KB is a target for glucocorticoid-mediated IL-8 gene repression J. Biol. Chem. 269 1994 13289 13295
    • (1994) J. Biol. Chem. , vol.269 , pp. 13289-13295
    • Mukaida, N.1    Morita, M.2    Ishikawa, Y.3    Rice, N.4    Okamoto, S.5    Kasahara, T.6    Matsushima, K.7
  • 35
    • 0009576874 scopus 로고
    • Individual antineoplastic drugs
    • A.B. Wingard J. Larner J. Schwartz Wolfe Publishing Ltd. London
    • A.E. Munson Individual antineoplastic drugs A.B. Wingard J. Larner J. Schwartz Human Pharmacology. Molecular to Clinical 1991 Wolfe Publishing Ltd. London 598 600
    • (1991) Human Pharmacology. Molecular to Clinical , pp. 598-600
    • Munson, A.E.1
  • 38
    • 0035213508 scopus 로고    scopus 로고
    • A central role for IL-2 in fate determination of mature T cells - I: Role in determining the Th1/Th2 profile in primary T cell cultures
    • K. Raju, B.A. Rabinovich, L.G. Radvanyi, D. Spaner, and R. Miller A central role for IL-2 in fate determination of mature T cells - I: role in determining the Th1/Th2 profile in primary T cell cultures Int. Immunol. 13 2001 1453 1459
    • (2001) Int. Immunol. , vol.13 , pp. 1453-1459
    • Raju, K.1    Rabinovich, B.A.2    Radvanyi, L.G.3    Spaner, D.4    Miller, R.5
  • 39
    • 0023934242 scopus 로고
    • Prospects in the immunological treatments of rheumatoid arthritis
    • J. Sany Prospects in the immunological treatments of rheumatoid arthritis Scand. J. Rheumatol. Suppl. 66 1987 129 136
    • (1987) Scand. J. Rheumatol. Suppl. , vol.66 , pp. 129-136
    • Sany, J.1
  • 41
    • 2342496204 scopus 로고    scopus 로고
    • Analgesic and anti-inflammatory activity of lactuca sativa seed extract in rats
    • M. Sayyah, N. Hadidi, and M. Kamalinejad Analgesic and anti-inflammatory activity of lactuca sativa seed extract in rats J. Ethnopharmacol. 92 2004 325 329
    • (2004) J. Ethnopharmacol. , vol.92 , pp. 325-329
    • Sayyah, M.1    Hadidi, N.2    Kamalinejad, M.3
  • 42
    • 0022133057 scopus 로고
    • Expression of interleukin 2 receptor on Hodgkin's and non-Hodgkin's lymphomas and macrophages
    • R. Schwarting, J. Gerdes, and H.J. Stein Expression of interleukin 2 receptor on Hodgkin's and non-Hodgkin's lymphomas and macrophages Clin. Pathol. (Lond.) 38 1985 1196 1197
    • (1985) Clin. Pathol. (Lond.) , vol.38 , pp. 1196-1197
    • Schwarting, R.1    Gerdes, J.2    Stein, H.J.3
  • 43
    • 0018136449 scopus 로고
    • Immunosuppressive activity of two plant steroidal lactones withaferin a and withanolide e
    • B. Shohat, I. Kirson, and D. Lavie Immunosuppressive activity of two plant steroidal lactones withaferin A and withanolide E Biomedicine 28 1978 18 24
    • (1978) Biomedicine , vol.28 , pp. 18-24
    • Shohat, B.1    Kirson, I.2    Lavie, D.3
  • 44
    • 0020645505 scopus 로고
    • In vitro absorption of [14C] leucine during inflammation and the effect of anti-inflammatory drugs in the jejunum of rats
    • S. Somasundaram, J. Sadique, and A. Subramoniam In vitro absorption of [14C] leucine during inflammation and the effect of anti-inflammatory drugs in the jejunum of rats Biochem. Med. 29 1983 259 264
    • (1983) Biochem. Med. , vol.29 , pp. 259-264
    • Somasundaram, S.1    Sadique, J.2    Subramoniam, A.3
  • 47
    • 0010599450 scopus 로고    scopus 로고
    • Enhancement of cell proliferation and cytokines production in human peripheral blood mononuclear cells by extracts from blood enriching Dang-Qui decoction
    • T. Tsai, C. Hseih, Y. Lin, W. Tsai, and Y.-C. Kuo Enhancement of cell proliferation and cytokines production in human peripheral blood mononuclear cells by extracts from blood enriching Dang-Qui decoction J. Chin. Med. 12 2001 191 202
    • (2001) J. Chin. Med. , vol.12 , pp. 191-202
    • Tsai, T.1    Hseih, C.2    Lin, Y.3    Tsai, W.4    Kuo, Y.-C.5
  • 48
    • 0029817355 scopus 로고    scopus 로고
    • Identification and characterization of two alternative splice variants of human interleukin-2
    • V.N. Tsytsikov, V.V. Yurovsky, S.P. Atamas, W.J. Alms, and B. White Identification and characterization of two alternative splice variants of human interleukin-2 J. Biol. Chem. 271 1996 23055 23060
    • (1996) J. Biol. Chem. , vol.271 , pp. 23055-23060
    • Tsytsikov, V.N.1    Yurovsky, V.V.2    Atamas, S.P.3    Alms, W.J.4    White, B.5
  • 49
    • 0027252110 scopus 로고
    • The IL-2/IL-2 receptor system: A target for rational immune intervention
    • T.A. Waldmann The IL-2/IL-2 receptor system: a target for rational immune intervention Immunol. Today 14 1993 264 270
    • (1993) Immunol. Today , vol.14 , pp. 264-270
    • Waldmann, T.A.1
  • 50
    • 0021253518 scopus 로고
    • Functional and phenotypic comparison of human T cell leukemia/lymphoma virus positive adult T cell leukemia with human T cell leukemia/lymphoma virus negative Sezary leukemia, and their distinction using anti-Tac. Monoclonal antibody identifying the human receptor for T cell growth factor
    • T.A. Waldmann, W.C. Greene, P.S. Sarin, C. Saxinger, D.W. Blayney, W.A. Blattner, C.K. Goldman, K. Bongiovanni, S. Sharrow, J.M. Depper, W. Leonard, T. Uchiyama, and R.C. Gallo Functional and phenotypic comparison of human T cell leukemia/lymphoma virus positive adult T cell leukemia with human T cell leukemia/lymphoma virus negative Sezary leukemia, and their distinction using anti-Tac. Monoclonal antibody identifying the human receptor for T cell growth factor J. Clin. Invest. 73 1984 1711 1718
    • (1984) J. Clin. Invest. , vol.73 , pp. 1711-1718
    • Waldmann, T.A.1    Greene, W.C.2    Sarin, P.S.3    Saxinger, C.4    Blayney, D.W.5    Blattner, W.A.6    Goldman, C.K.7    Bongiovanni, K.8    Sharrow, S.9    Depper, J.M.10    Leonard, W.11    Uchiyama, T.12    Gallo, R.C.13


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