Skeletons in the p53 tumor suppressor closet: Genetic evidence that p53 blocks bone differentiation and development

Journal of Cell Biology

Volumn 172, Issue 6, 2006, Pages 795-797

  Zambetti, Gerard P ^a   Horwitz, Edwin M ^a   Schipani, Ernestina ^b  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COLONY STIMULATING FACTOR 1; OSTEOCLAST DIFFERENTIATION FACTOR; PROTEIN MDM2; PROTEIN P53; TRANSCRIPTION FACTOR RUNX1; TUMOR NECROSIS FACTOR; TUMOR SUPPRESSOR PROTEIN; UBIQUITIN PROTEIN LIGASE E3;

ANTIBODY PRODUCTION; APOPTOSIS; BONE DEVELOPMENT; BONE METABOLISM; BONE TURNOVER; CELL ACTIVITY; CELL CYCLE ARREST; CELL DIFFERENTIATION; CELL MATURATION; GENE DELETION; HUMAN; MESENCHYME CELL; NEGATIVE FEEDBACK; NONHUMAN; OSTEOBLAST; OSTEOCLAST; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN FUNCTION; REVIEW; SARCOMA; SIGNAL TRANSDUCTION;

ANIMALS; BONE DEVELOPMENT; CELL DIFFERENTIATION; CELL TRANSFORMATION, NEOPLASTIC; CORE BINDING FACTOR ALPHA 1 SUBUNIT; HUMANS; MICE; MICE, KNOCKOUT; OSTEOBLASTS; PROTO-ONCOGENE PROTEINS C-MDM2; TRANSCRIPTION FACTORS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 33644910689     PISSN: 00219525     EISSN: 00219525     Source Type: Journal    
DOI: 10.1083/jcb.200601114     Document Type: Review

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