Possible role of Fas/Fas ligand-mediated apoptosis in the pathogenesis of fixed drug eruption

British Journal of Dermatology

Volumn 154, Issue 3, 2006, Pages 419-425

  Choi, H J ^a   Ku, J K ^a   Kim, M Y ^a   Kang, H ^a   Cho, S H ^a   Kim, H O ^a   Park, Y M ^a  

^a The Catholic University of Korea   (South Korea)

Author keywords

Apoptosis; CD8+ T cells; Fas; Fas ligand; Fixed drug eruption

Indexed keywords

ACETYLSALICYLIC ACID; AMOXICILLIN; CASPASE 3; CEFACLOR; CEPHALOSPORIN; CODEINE; COTRIMOXAZOLE; DOXYCYCLINE; FAS ANTIGEN; FAS LIGAND; IBUPROFEN; LEVOFLOXACIN; MEFENAMIC ACID; OFLOXACIN; PARACETAMOL; PHENAZONE; PIROXICAM; PREDNISOLONE; TETRACYCLINE;

ADULT; AGED; ANTIGEN EXPRESSION; APOPTOSIS; ARTICLE; BASAL CELL; CD8+ T LYMPHOCYTE; CELL DEATH; CELL INFILTRATION; CLINICAL ARTICLE; CYTOTOXICITY; ENZYME ANALYSIS; FEMALE; FIXED DRUG ERUPTION; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; KERATINOCYTE; MALE; MONONUCLEAR CELL; NICK END LABELING; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SCHOOL CHILD; SKIN CELL; T LYMPHOCYTE SUBPOPULATION;

ADULT; AGED; ANTIGENS, CD95; APOPTOSIS; CASPASE 3; CASPASES; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CHILD; DRUG ERUPTIONS; FAS LIGAND PROTEIN; FEMALE; HUMANS; IMMUNOENZYME TECHNIQUES; IN SITU NICK-END LABELING; KERATINOCYTES; MALE; MEMBRANE GLYCOPROTEINS; MIDDLE AGED; PORE FORMING CYTOTOXIC PROTEINS; SIGNAL TRANSDUCTION; TUMOR NECROSIS FACTORS;

EID: 33644898100     PISSN: 00070963     EISSN: 13652133     Source Type: Journal    
DOI: 10.1111/j.1365-2133.2005.07057.x     Document Type: Article

References (28)

1. Teraki Y Shiohara T IFN-gamma-producing effector CD8+ T cells and IL-10-producing regulatory CD4+ T cells in fixed drug eruption J Allergy Clin Immunol 2003 112 609 15
2. Weedon D Apoptosis Adv Dermatol 1990 5 243 54
3. Korkij W Soltani K Fixed drug eruption. A brief review Arch Dermatol 1984 120 520 4
4. French LE Tschopp J Fas-mediated cell death in toxic epidermal necrolysis and graft-versus-host disease: potential for therapeutic inhibition Schweiz Med Wochenschr 2000 130 1656 61
5. Wehrli P Viard I Bullani R et al. Death receptors in cutaneous biology and disease J Invest Dermatol 2000 115 141 8
6. Inachi S Mizutani H Shimizu M Epidermal apoptotic cell death in erythema multiforme and Stevens-Johnson syndrome. Contribution of perforin-positive cell infiltration Arch Dermatol 1997 133 845 9
7. Langley RG Walsh N Nevill T et al. Apoptosis is the mode of keratinocyte death in cutaneous graft-versus-host disease J Am Acad Dermatol 1996 35 187 90
8. Kumar V Abbas AK Fausto N Cellular adaptations, cell injury, and cell death. In: Robbins and Cotran Pathologic Basis of Disease Robbins SL Cotran RS Kumar V Collins T, eds) 7th edn
9. Itoh N Yonehara S Ishii A et al. The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis Cell 1991 66 233 43
10. Nagata S Golstein P The Fas death factor Science 1995 267 1449 56
11. Walczak H Krammer PH The CD95 (APO-1/Fas) and the TRAIL (APO-2L) apoptosis systems Exp Cell Res 2000 256 58 66
12. Riedl SJ Shi Y Molecular mechanisms of caspase regulation during apoptosis Nat Rev Mol Cell Biol 2004 5 897 907
13. Mizukawa Y Yamazaki Y Teraki Y et al. Direct evidence for interferon-gamma production by effector-memory-type intraepidermal T cells residing at an effector site of immunopathology in fixed drug eruption Am J Pathol 2002 161 1337 47
14. Hindsen M Christensen OB Gruic V Lofberg H. Fixed drug eruption: an immunohistochemical investigation of the acute and healing phase Br J Dermatol 1987 116 351 60
15. Shiohara T Mizukawa Y Teraki Y Pathophysiology of fixed drug eruption: the role of skin-resident T cells Curr Opin Allergy Clin Immunol 2002 2 317 23
16. Viard-Leveugle I Bullani RR Meda P et al. Intracellular localization of keratinocyte Fas ligand explains lack of cytolytic activity under physiological conditions J Biol Chem 2003 278 16183 8
17. Shiohara T Moriya N Nagashima M The lichenoid tissue reaction. A new concept of pathogenesis Int J Dermatol 1988 27 365 74
18. Teraki Y Shiohara T Successful desensitization to fixed drug eruption: the presence of CD25+CD4+ T cells in the epidermis of fixed drug eruption lesions may be involved in the induction of desensitization Dermatology 2004 209 29 32
19. Teraki Y Moriya N Shiohara T Drug-induced expression of intercellular adhesion molecule-1 on lesional keratinocytes in fixed drug eruption Am J Pathol 1994 145 550 60
20. Shiohara T Moriya N Epidermal T cells: their functional role and disease relevance for dermatologists J Invest Dermatol 1997 109 271 5
21. Matsue H Kobayashi H Hosokawa T et al. Keratinocytes constitutively express the Fas antigen that mediates apoptosis in IFN gamma-treated cultured keratinocytes Arch Dermatol Res 1995 287 315 20
22. Yamauchi R Morita A Tsuji T Fixed drug eruption caused by iopamidol, a contrast medium J Dermatol 1997 24 243 5
23. Alderson MR Armitage RJ Maraskovsky E et al. Fas transduces activation signals in normal human T lymphocytes J Exp Med 1993 178 2231 5
24. Biancone L Martino AD Orlandi V et al. Development of inflammatory angiogenesis by local stimulation of Fas in vivo J Exp Med 1997 186 147 52
25. Restifo NP Not so Fas: re-evaluating the mechanisms of immune privilege and tumor escape Nat Med 2000 6 493 5
26. Hohlbaum AM Moe S Marshak-Rothstein A Opposing effects of transmembrane and soluble Fas ligand expression on inflammation and tumor cell survival J Exp Med 2000 191 1209 20
27. Yawalkar N Pichler WJ Immunohistology of drug-induced exanthema: clues to pathogenesis Curr Opin Allergy Clin Immunol 2001 1 299 303
28. Yawalkar N Pichler WJ Pathogenesis of drug-induced exanthema Int Arch Allergy Immunol 2001 124 336 8