Intracellular localization of keratinocyte Fas ligand explains lack of cytolytic activity under physiological conditions

Journal of Biological Chemistry

Volumn 278, Issue 18, 2003, Pages 16183-16188

  Viard Leveugle, Isabelle ^a   Bullani, Roberto R ^a   Meda, Paolo ^a   Micheau, Olivier ^b   Limat, Alain ^a   Saurat, Jean Hilaire ^a   Tschopp, Jürg ^b   French, Lars E ^a  

^a UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; CELL CULTURE; CELLS; CHEMICAL BONDS; ELECTRON MICROSCOPY; FLUORESCENCE; METALLORGANIC POLYMERS; PROTEINS;

CELL DEATH;

CYTOLOGY;

FAS ANTIGEN; FAS LIGAND; METALLOPROTEINASE INHIBITOR; CARRIER PROTEIN; FADD PROTEIN, HUMAN; FAS ASSOCIATED DEATH DOMAIN PROTEIN; FASLG PROTEIN, HUMAN; MEMBRANE PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN;

APOPTOSIS; ARTICLE; CELL CULTURE; CELL DEATH; CELL SURFACE; CONCENTRATION RESPONSE; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOLYSIS; DRUG ERUPTION; ELECTRON MICROSCOPY; EMBRYO; EPIDERMIS; FLUORESCENCE ACTIVATED CELL SORTING; HUMAN; HUMAN CELL; IN VITRO STUDY; KERATINOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; TOXIC EPIDERMAL NECROLYSIS; CHEMISTRY; CYTOLOGY; CYTOPLASM; IMMUNOELECTRON MICROSCOPY; PHYSIOLOGY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; APOPTOSIS; CARRIER PROTEINS; CELLS, CULTURED; CYTOPLASM; FAS LIGAND PROTEIN; FAS-ASSOCIATED DEATH DOMAIN PROTEIN; HUMANS; KERATINOCYTES; MEMBRANE GLYCOPROTEINS; MICROSCOPY, IMMUNOELECTRON;

EID: 0037507304     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M212188200     Document Type: Article

References (30)

1. Suda, T., Takahashi, T., Golstein, P., and Nagata, S. (1993) Cell 75, 1169-1178
2. Itoh, N., Yonehara, S., Ishii, A., Yonehara, M., Mizushima, S., Sameshima, M., Hase, A., Seto, Y., and Nagata, S. (1991) Cell 66, 233-243
3. Trauth, B. C., Klas, C., Peters, A. M., Matzku, S., Moller, P., Falk, W., and Krammer, P. H. (1989) Science 245, 301-305
4. Itoh, N., and Nagata, S. (1993) J. Biol. Chem. 268, 10932-10937
5. Tartaglia, L. A., Ayres, T. M., Wong, G. H., and Goeddel, D. V. (1993) Cell 74, 845-853
6. Boldin, M. P., Varfolomeev, E. E., Pancer, C., Mett, I. L., Camonis, J. H., and Wallach, D. (1995) J. Biol. Chem. 270, 7795-7798
7. Chinnaiyan, A. M., O'Rourke, K., Tewari, M., and Dixit, V. M. (1995) Cell 81, 505-512
8. Boldin, M. P., Goncharov, T. M., Goltsev, Y. V., and Wallach, D. (1996) Cell 85, 803-815
9. Muzio, M., Chinnaiyan, A. M., Kischkel, F. C., O'Rourke, K., Schevchenko, A., Ni, J., Scaffidi, C., Bretz, J. D., Zhang, M., Gentz, R., Mann, M., Krammer, P. H., Peter, M. E., and Dixit, V. M. (1996) Cell 85, 817-827
10. Hill, L. L., Ouhtit, A., Loughlin, S. M., Kripke, M. L., Ananthaswamy, H. N., and Owen-Schaub, L. B. (1999) Science 285, 898-900
11. Viard, I., Wehrli, P., Bullani, R., Schneider, P., Holler, N., Salomon, D., Hunziker, T., Saurat, J. H., Tschopp, J., and French, L. E. (1998) Science 282, 490-493
12. Baker, M. B., Altman, N. H., Podack, E. R., and Levy, R. B. (1996) J. Exp. Med. 183, 2645-2656
13. Braun, M. Y., Lowin, B., French, L., Acha-Orbea, H., and Tschopp, J. (1996) J. Exp. Med. 183, 657-661
14. Leithauser, F., Dhein, J., Mechtersheimer, G., Koretz, K., Bruderlein, S., Henne, C., Schmidt, A., Debatin, K. M., Krammer, P. H., and Moller, P. (1993) Lab. Invest. 69, 415-429
15. Sayama, K., Watanabe, Y., Tohyama, M., and Miki, Y. (1994) Dermatology 188, 305-309
16. Oishi, M., Sugiyama, S., and Maeda, K. (1994) Arch. Dermatol. Res. 286, 396-407
17. Matsue, H., Akitaya, T., Kobayashi, H., Ohkawara, A., and Hosokawa, T. (1995) Arch. Dermatol. Res. 287, 315-320
18. Gutierrez-Steil, C., Wrone-Smith, T., Sun, X., Krueger, J. G., Coven, T., and Nickoloff, B. J. (1998) J. Clin. Invest. 101, 33-39
19. Berthou, C., Michel, L., Soulie, A., Jean-Louis, F., Flageul, B., Dubertret, L., Sigaux, F., Zhang, Y., and Sasportes, M. (1997) J. Immunol. 159, 5293-5300
20. Arnold, R., Seifert, M., Asadullah, K., and Volk, H. D. (1999) J. Immunol. 162, 7140-7147
21. Leverkus, M., Yaar, M., and Gilchrest, B. A. (1997) Exp. Cell Res. 232,255-262
22. Limat, A., Hunziker, T., Boillat, C., Bayreuther, K., and Noser, F. (1989) J. Invest. Dermatol. 92, 758-762
23. French, L. E., Hahne, M., Viard, I., Radlgruber, G., Zanone, R., Becker, K., Muller, C., and Tschopp, J. (1996) J. Cell Biol. 133, 335-343
24. Kantor, R. R., Mattes, M. J., Lloyd, K. O., Old, L. J., and Albino, A. P. (1987) J. Biol. Chem. 262, 15158-15165
25. Wehrli, P., Viard, I., Bullani, R., Tschopp, J., and French, L. E. (2000) J. Invest. Dermatol. 115, 141-148
26. McCall, C. A., and Cohen, J. J. (1991) J. Invest. Dermatol. 97, 111-114
27. Kayagaki, N., Kawasaki, A., Ebata, T., Ohmoto, H., Ikeda, S., Inoue, S., Yoshino, K., Okumura, K., and Yagita, H. (1995) J. Exp. Med. 182, 1777-1783
28. Mariani, S. M., Matiba, B., Bäumler, C., and Krammer, P. H. (1995) Eur. J. Immunol. 25, 2303-2307
29. Bossi, G., and Griffiths, G. M. (1999) Nat. Med. 5, 90-96
30. Guilherme, A., Emoto, M., Buxton, J. M., Bose, S., Sabini, R., Theurkauf, W. E., Lezyk, J., and Czech, M. P. (2000) J. Biol. Chem. 275, 38151-38159