Steroids or cocktails for alcoholic hepatitis

Journal of Hepatology

Volumn 44, Issue 4, 2006, Pages 633-636

  O'Shea, Robert ^a   McCullough, Arthur J ^a  

^a CLEVELAND CLINIC LERNER COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCYSTEINE; ALLOPURINOL; ALPHA TOCOPHEROL; ANTIOXIDANT; ASCORBIC ACID; BETA CAROTENE; CORTICOSTEROID; DEFEROXAMINE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; ISOPROSTANE DERIVATIVE; METHIONINE; PENTOXIFYLLINE; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; RETINOL; SELENIUM;

ALCOHOL LIVER DISEASE; CLINICAL TRIAL; DISEASE SEVERITY; DRUG EFFECT; DRUG EFFICACY; EDITORIAL; GASTROINTESTINAL HEMORRHAGE; GASTROINTESTINAL INFECTION; HUMAN; LIVER BIOPSY; LIVER TOXICITY; OXIDATIVE STRESS; PANCREATITIS; PRIORITY JOURNAL; TREATMENT OUTCOME;

ADRENAL CORTEX HORMONES; ANTIOXIDANTS; DRUG THERAPY, COMBINATION; HEPATITIS, ALCOHOLIC; HUMANS; OXIDATIVE STRESS; PENTOXIFYLLINE; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME;

EID: 33644896863     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2006.01.011     Document Type: Editorial

References (31)

1. R.S. O'Shea, and A.J. McCullough Treatment of alcoholic hepatitis Clin Liv Dis 2005 103 134
2. W.C. Maddrey, J.K. Boitnott, M.S. Bedine, F.L. Weber Jr, E. Mezey, and R.I. White Jr Corticosteroid therapy of alcoholic hepatitis Gastroenterology 75 1978 193 199
3. T.F. Impteriale, and A.J. McCullough Do corticosteroids reduce mortality from alcoholic hepatitis? Ann Intern Med 113 1990 299 307
4. M.J. Ramond, T. Poynard, B. Rueff, P. Mathur, C. Theodore, and J.C. Chaput A randomized trial of prednisolone in patients with severe alcoholic hepatitis N Engl J Med 326 1992 507 512
5. R.L. Carithers, H.F. Herlong, A.M. Diehl, E.W. Shaw, B. Combes, and H.J. Fallon Methylprednisolone therapy in patients with severe alcoholic hepatitis: a randomized multicenter trial Ann Intern Med 110 1989 685 690
6. P. Mathurin, V. Duchatelle, M.J. Ramond, C. Degott, P. Bedossa, and S. Erlinger Survival and prognostic factors in patients with severe alcoholic hepatitis treated with prednisolone Gastroenterology 110 1996 1847 1855
7. A.J. McCullough, and B. O'Connor The American College of Gastroenterology position paper on the therapy of alcoholic liver disease Am J Gastroenterol 93 1998 2022 2036
8. C.L. Mendenhall, S. Anderson, P. Garcia-Pont, S. Goldberg, T Kiernan, and L.B. Seeff Short-term and long-term survival in patients with alcoholic hepatitis treated with oxandrolone and prednisolone N Engl J Med 311 1984 1464 1470
9. P. Mathurin, C.L. Mendenhall, R.L. Carithers, M.J. Ramond, W.C. Maddrey, and P. Garstide Corticosteroids improve short-term survival in patients with severe alcoholic hepatitis (AH): individual data analysis of the last three randomized placebo controlled double-blind trials of corticosteroids in severe AH J Hepatol 36 2002 480 487
10. E. Akriviadis, R. Botla, W. Briggs, S. Han, T. Reynolds, and O. Shakil Pentoxifylline improves short-term survival in severe acute alcoholic hepatitis: a double-blind, placebo-controlled trial Gastroenterology 119 2000 1787 1791
11. M. Phillips, H. Curtis, B. Portmann, N. Donaldson, A. Bomford, and J. O'Grady Antioxidants versus corticosteroids in the treatment of severe alcoholic hepatitis-A randomized clinical trial J Hepatol 44 2006 784 790
12. T. Zima, E. Alhano, M. Ingelman-Sundberg, G.E. Arteel, G.M. Thiele, and L.W. Klassen Modulation of oxidative stress by alcohol Alcohol Clin Exp Res 29 2005 1060 1065
13. G.E. Arteel Oxidants and anti-oxidants in alcohol-induced liver disease Gastroenterology 124 2003 778 790
14. W. Dunn, L.H. Jamil, L.S. Brown, R.H. Wiesner, W.R. Kim, and K.V. Menon MELD accurately predicts mortality in patients with alcoholic hepatitis Hepatology 8 2005 495
15. W. Srikureja, N.L. Kyalo, B.A. Runyon, and K.Q. Hu MELD score is a better prognostic model than Child-Turcotte-Pugh score or discriminant function score in patients with alcoholic hepatitis J Hepatol 42 2005 700 706
16. E. Forrest, S. Singhal, G. Haydon, C. Day, N. Fisher, and A. Brind Grading alcoholic hepatitis Hepatology 42 2005 495 496
17. E. Mezey, and J.J. Potter A randomized placebo controlled trial of Vitamin E for alcoholic hepatitis J Hepatol 40 2004 40 46
18. M.P. de la Maza, M. Pterman, D. Bunout, and S. Hirsh Effects of long-term vitamin supplementation in alcoholic cirrhotics J Am Coll Nutr 14 1995 192 196
19. J. Levitsky, and M.E. Malliard Diagnosis and therapy of alcoholic liver disease Semin Liv Dis 24 2004 233 247
20. E.R. Miller, R. Pastor-Barriuso, D. Dalal, R.A. Riemersma, L.J. Appel, and E. Guellar Meta-analysis: high dose Vitamin E supplementation may increase all-cause mortality Ann Intern Med 142 2005 37 46
21. E. Meagher, O.P. Barry, J.A. Lawson, J. Rokach, and G. Fitzgerald Effects of vitamin E on lipid peroxidation in healthy persons JAMA 285 2001 1178 1182
22. S.R. Thomas, and R. Stocker Molecular action of Vitamin E in lipoprotein oxidation: implications for atherosclerosis Free Radiol Biol Med 28 2000 1795 1805
23. I.D. Podmore, H.R. Griffiths, K.E. Herbert, N. Mistry, P. Mistry, and J. Lunec Vitamin C exhibits pro-oxidant properties Nature 392 1998 559 April 9
24. L.J. Roberts, and J.D. Morrow Measurement of F(2) isoprostanes as an index of oxidative stress in vivo Free Radiol Biol Med 28 2000 505 513
25. C. Leeuwenburgh, M.M. Hardy, S.L. Hazen, P. Wagner, S. Oh-ishi, and U.P. Steinbrecher Reactive nitrogen intermediates promote low density lipoprotein oxidation in human atherosclerotic intima J Biol Chem 272 1997 1433 1436
26. S.L. Hazen, and J.W. Heinecke 3-Chlorotyrosine, a specific marker of myeloperoxidase catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima J Clin Invest 99 1997 2075 2081
27. A. Parlesak, C. Schafer, S.B. Paulus, S.D. Hammes, J.P. Diedrich, and C. Bode Phagocytosis and production of reactive oxygen species by peripheral blood phagocytes in patients with different stages of alcohol-induced liver disease: effect of acute exposure to low ethanol concentrations Alcohol Clin Exp Res 3 2003 503 508
28. C.J. McClain, D.B. Hill, Z. Song, I. Deacius, and S. Barve Monocyte activation in alcoholic liver disease Alcohol 27 2002 53 61
29. H.M. Abu-soud, and S.L. Hazen Nitric oxide modulates the catalytic activity of myeloperoxidase JBC 275 2000 5425 5430
30. L. Tao, H.R. Liu, E. Gao, Z.P. Teng, B.L. Lopez, and T.A. Christopher Antioxidative, antinitrative, and vasculoprotective effects of a peroxisome proliferator-activated receptor-gamma agonist in hypercholesterolemia Circulation 108 2003 2805 2811
31. M.H. Shishehbor, R.J. Aviles, M.L. Brennan, X. Fu, M. Goormastic, and G.L. Pearce Association of nitrotyrosine levels with cardiovascular disease and modulation by statin therapy JAMA 289 2003 1675 1680