메뉴 건너뛰기




Volumn 29, Issue 2, 2006, Pages 313-322

The effects of maternal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin on testicular steroidogenesis in infantile male rats

Author keywords

Dioxin; Rat; Steroid acute regulatory protein; Testis; Testosterone

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; ANDROGEN; CYCLIC AMP; FOLLITROPIN; LUTEINIZING HORMONE; REGULATOR PROTEIN; STEROID ACUTE REGULATORY PROTEIN; TESTOSTERONE; UNCLASSIFIED DRUG;

EID: 33644890768     PISSN: 01056263     EISSN: 13652605     Source Type: Journal    
DOI: 10.1111/j.1365-2605.2005.00568.x     Document Type: Article
Times cited : (13)

References (54)
  • 1
    • 0024210242 scopus 로고
    • Pharmacokinetics and biological activity of 2,3,7,8-tetrachlorodibenzo-p- dioxin. 1. Dose-dependent tissue distribution and induction of hepatic ethoxyresorufin O-deethylase in rats following a single injection
    • Abraham K. Krowke R. Neubert D. 1988 Pharmacokinetics and biological activity of 2,3,7,8-tetrachlorodibenzo-p-dioxin. 1. Dose-dependent tissue distribution and induction of hepatic ethoxyresorufin O-deethylase in rats following a single injection Archives of Toxicology 62 359 368
    • (1988) Archives of Toxicology , vol.62 , pp. 359-368
    • Abraham, K.1    Krowke, R.2    Neubert, D.3
  • 2
    • 0029586657 scopus 로고
    • Developmental effects of dioxins and related endocrine disrupting chemicals
    • Birnbaum L. S. 1995 Developmental effects of dioxins and related endocrine disrupting chemicals Toxicology Letters 82-83 743 750
    • (1995) Toxicology Letters , vol.82-83 , pp. 743-750
    • Birnbaum, L.S.1
  • 3
    • 0027956142 scopus 로고
    • Reproductive toxicity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin in male rats: Different effects of in utero versus lactational exposure
    • Bjerke D. L. Peterson R. E. 1994 Reproductive toxicity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin in male rats: different effects of in utero versus lactational exposure Toxicology and Applied Pharmacology 127 241 249
    • (1994) Toxicology and Applied Pharmacology , vol.127 , pp. 241-249
    • Bjerke, D.L.1    Peterson, R.E.2
  • 4
    • 0017184389 scopus 로고
    • A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford M. M. 1976 A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Analytical Biochemistry 72 248 254
    • (1976) Analytical Biochemistry , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 5
    • 0034026589 scopus 로고    scopus 로고
    • Development of time-resolved immunofluorometric assays for rat follicle-stimulating hormone and luteinizing hormone and application on sera of cycling rats
    • van Casteren J. I. Schoonen W. G. Kloosterboer H. J. 2000 Development of time-resolved immunofluorometric assays for rat follicle-stimulating hormone and luteinizing hormone and application on sera of cycling rats Biology of Reproduction 62 886 894
    • (2000) Biology of Reproduction , vol.62 , pp. 886-894
    • Van Casteren, J.I.1    Schoonen, W.G.2    Kloosterboer, H.J.3
  • 6
    • 0024428640 scopus 로고
    • Reproductive toxicity and pharmacokinetics of 2,3,7,8-tetrachlorodibenzo- p-dioxin. 1. Effects of high doses on the fertility of male rats
    • Chahoud I. Krowke R. Schimmel A. Merker H. J. Neubert D. 1989 Reproductive toxicity and pharmacokinetics of 2,3,7,8-tetrachlorodibenzo-p- dioxin. 1. Effects of high doses on the fertility of male rats Archives of Toxicology 63 432 439
    • (1989) Archives of Toxicology , vol.63 , pp. 432-439
    • Chahoud, I.1    Krowke, R.2    Schimmel, A.3    Merker, H.J.4    Neubert, D.5
  • 7
    • 0035370160 scopus 로고    scopus 로고
    • Disposition of polychlorinated dibenzo-p-dioxins, dibenzofurans, and non-ortho polychlorinated biphenyls in pregnant Long Evans rats and the transfer to offspring
    • Chen C. Y. Hamm J. T. Hass J. R. Birnbaum L. S. 2001 Disposition of polychlorinated dibenzo-p-dioxins, dibenzofurans, and non-ortho polychlorinated biphenyls in pregnant Long Evans rats and the transfer to offspring Toxicology and Applied Pharmacology 173 65 88
    • (2001) Toxicology and Applied Pharmacology , vol.173 , pp. 65-88
    • Chen, C.Y.1    Hamm, J.T.2    Hass, J.R.3    Birnbaum, L.S.4
  • 8
    • 0032213192 scopus 로고    scopus 로고
    • Effects of in utero and lactational exposure to 2,3,7,8- tetrachlorodibenzo-p-dioxin (TCDD) on serum androgens and steroidogenic enzyme activities in the male rat reproductive tract
    • Cooke G. M. Price A. Oko R. J. 1998 Effects of in utero and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on serum androgens and steroidogenic enzyme activities in the male rat reproductive tract Journal of Steroid Biochemistry and Molecular Biology 67 347 354
    • (1998) Journal of Steroid Biochemistry and Molecular Biology , vol.67 , pp. 347-354
    • Cooke, G.M.1    Price, A.2    Oko, R.J.3
  • 9
    • 0029148419 scopus 로고
    • Comparisons of estimated human body burdens of dioxinlike chemicals and TCDD body burdens in experimentally exposed animals
    • DeVito M. J. Birnbaum L. S. Farland W. H. Gasiewicz T. A. 1995 Comparisons of estimated human body burdens of dioxinlike chemicals and TCDD body burdens in experimentally exposed animals Environmental Health Perspectives 103 820 831
    • (1995) Environmental Health Perspectives , vol.103 , pp. 820-831
    • Devito, M.J.1    Birnbaum, L.S.2    Farland, W.H.3    Gasiewicz, T.A.4
  • 11
    • 0032103386 scopus 로고    scopus 로고
    • Reproductive toxicity and tissue concentrations of low doses of 2,3,7,8-tetrachlorodibenzo-p-dioxin in male offspring rats exposed throughout pregnancy and lactation
    • Faqi A. S. Dalsenter P. R. Merker H. J. Chahoud I. 1998 Reproductive toxicity and tissue concentrations of low doses of 2,3,7,8-tetrachlorodibenzo-p- dioxin in male offspring rats exposed throughout pregnancy and lactation Toxicology and Applied Pharmacology 150 383 392
    • (1998) Toxicology and Applied Pharmacology , vol.150 , pp. 383-392
    • Faqi, A.S.1    Dalsenter, P.R.2    Merker, H.J.3    Chahoud, I.4
  • 13
    • 84907133160 scopus 로고
    • Onset of steroidogenesis and differentiation of functional LH receptors in rat fetal testicular cultures
    • Gangnerau M. N. Picon R. 1987 Onset of steroidogenesis and differentiation of functional LH receptors in rat fetal testicular cultures Archives of Andrology 18 215 224
    • (1987) Archives of Andrology , vol.18 , pp. 215-224
    • Gangnerau, M.N.1    Picon, R.2
  • 14
    • 0028916903 scopus 로고
    • Exposure to TCDD during development permanently alters reproductive function in male Long-Evans rats and hamsters: Reduced ejaculated and epididymal sperm numbers and sex accessory gland weights in offspring with normal androgenic status
    • Gray L. E. Kelce W. R. Monosson E. Ostby J. S. Birnbaum L. S. 1995 Exposure to TCDD during development permanently alters reproductive function in male Long-Evans rats and hamsters: reduced ejaculated and epididymal sperm numbers and sex accessory gland weights in offspring with normal androgenic status Toxicology and Applied Pharmacology 131 108 118
    • (1995) Toxicology and Applied Pharmacology , vol.131 , pp. 108-118
    • Gray, L.E.1    Kelce, W.R.2    Monosson, E.3    Ostby, J.S.4    Birnbaum, L.S.5
  • 15
    • 0342601484 scopus 로고    scopus 로고
    • A dose-response analysis of the reproductive effects of a single gestational dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin in male Long Evans Hooded rat offspring
    • Gray L. E. Ostby J. S. Kelce W. R. 1997 A dose-response analysis of the reproductive effects of a single gestational dose of 2,3,7,8-tetrachlorodibenzo- p-dioxin in male Long Evans Hooded rat offspring Toxicology and Applied Pharmacology 146 11 20
    • (1997) Toxicology and Applied Pharmacology , vol.146 , pp. 11-20
    • Gray, L.E.1    Ostby, J.S.2    Kelce, W.R.3
  • 17
    • 0035912878 scopus 로고    scopus 로고
    • Prenatal testosterone and luteinizing hormone levels in male rats exposed during pregnancy to 2,3,7,8-tetrachlorodibenzo-p-dioxin and diethylstilbestrol
    • Haavisto T. E. Nurmela K. Pohjanvirta R. Huuskonen H. El Gehani F. Paranko J. 2001 Prenatal testosterone and luteinizing hormone levels in male rats exposed during pregnancy to 2,3,7,8-tetrachlorodibenzo-p-dioxin and diethylstilbestrol Molecular and Cellular Endocrinology 178 169 179
    • (2001) Molecular and Cellular Endocrinology , vol.178 , pp. 169-179
    • Haavisto, T.E.1    Nurmela, K.2    Pohjanvirta, R.3    Huuskonen, H.4    El Gehani, F.5    Paranko, J.6
  • 18
    • 0242318890 scopus 로고    scopus 로고
    • Effects of 4-tert-octylphenol, 4-tert-butylphenol, and diethylstilbestrol on prenatal testosterone surge in the rat
    • Haavisto T. E. Adamsson N. Annika M. Sari A. Toppari J. Paranko J. 2003 Effects of 4-tert-octylphenol, 4-tert-butylphenol, and diethylstilbestrol on prenatal testosterone surge in the rat Reproductive Toxicology 17 593 605
    • (2003) Reproductive Toxicology , vol.17 , pp. 593-605
    • Haavisto, T.E.1    Adamsson, N.2    Annika, M.3    Sari, A.4    Toppari, J.5    Paranko, J.6
  • 19
    • 0021245267 scopus 로고
    • Testosterone, dihydrotestosterone and estradiol-17 beta levels in maternal and fetal plasma and in fetal testes in the rat
    • Habert R. Picon R. 1984 Testosterone, dihydrotestosterone and estradiol-17 beta levels in maternal and fetal plasma and in fetal testes in the rat Journal of Steroid Biochemistry 21 193 198
    • (1984) Journal of Steroid Biochemistry , vol.21 , pp. 193-198
    • Habert, R.1    Picon, R.2
  • 20
  • 21
    • 0024498263 scopus 로고
    • Kinetic studies on the development of the adult population of Leydig cells in testes of the pubertal rat
    • Hardy M. P. Zirkin B. R. Ewing L. L. 1989 Kinetic studies on the development of the adult population of Leydig cells in testes of the pubertal rat Endocrinology 124 762 770
    • (1989) Endocrinology , vol.124 , pp. 762-770
    • Hardy, M.P.1    Zirkin, B.R.2    Ewing, L.L.3
  • 23
    • 0026739968 scopus 로고
    • Reduced Leydig cell volume and function in adult rats exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin without a significant effect on spermatogenesis
    • Johnson L. Dickerson R. Safe S. H. Nyberg C. L. Lewis R. P. Welsh T. H. Jrq8 1992 Reduced Leydig cell volume and function in adult rats exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin without a significant effect on spermatogenesis Toxicology 76 103 118
    • (1992) Toxicology , vol.76 , pp. 103-118
    • Johnson, L.1    Dickerson, R.2    Safe, S.H.3    Nyberg, C.L.4    Lewis, R.P.5    Welsh Jr., T.H.6
  • 24
    • 0028348954 scopus 로고
    • 2,3,7,8-tetrachlorodibenzo-p-dioxin reduces the number, size, and organelle content of Leydig cells in adult rat testes
    • Johnson L. Wilker C. E. Safe S. H. Scott B. Dean D. D. White P. H. 1994 2,3,7,8-tetrachlorodibenzo-p-dioxin reduces the number, size, and organelle content of Leydig cells in adult rat testes Toxicology 89 49 65
    • (1994) Toxicology , vol.89 , pp. 49-65
    • Johnson, L.1    Wilker, C.E.2    Safe, S.H.3    Scott, B.4    Dean, D.D.5    White, P.H.6
  • 25
    • 0023783567 scopus 로고
    • The fate of fetal Leydig cells during the development of the fetal and postnatal rat testis
    • Kerr J. B. Knell C. M. 1988 The fate of fetal Leydig cells during the development of the fetal and postnatal rat testis Development 103 535 544
    • (1988) Development , vol.103 , pp. 535-544
    • Kerr, J.B.1    Knell, C.M.2
  • 26
    • 0025648069 scopus 로고
    • Inhibition of testicular steroidogenesis in 2,3,7,8-tetrachlorodibenzo-p- dioxin-treated rats: Evidence that the key lesion occurs prior to or during pregnenolone formation
    • Kleeman J. M. Moore R. W. Peterson R. E. 1990 Inhibition of testicular steroidogenesis in 2,3,7,8-tetrachlorodibenzo-p-dioxin-treated rats: evidence that the key lesion occurs prior to or during pregnenolone formation Toxicology and Applied Pharmacology 106 112 125
    • (1990) Toxicology and Applied Pharmacology , vol.106 , pp. 112-125
    • Kleeman, J.M.1    Moore, R.W.2    Peterson, R.E.3
  • 27
    • 77957187147 scopus 로고
    • Toxicokinetics of 2,3,7,8-tetrachlorodibenzo-p-dioxin in female Sprague-Dawley rats including placental and lactational transfer to fetuses and neonates
    • Li X. Weber L. W. Rozman K. K. 1995 Toxicokinetics of 2,3,7,8-tetrachlorodibenzo-p-dioxin in female Sprague-Dawley rats including placental and lactational transfer to fetuses and neonates Fundamental and Applied Toxicology 27 70 76
    • (1995) Fundamental and Applied Toxicology , vol.27 , pp. 70-76
    • Li, X.1    Weber, L.W.2    Rozman, K.K.3
  • 28
    • 0026755842 scopus 로고
    • In utero and lactational exposure of male rats to 2,3,7,8- tetrachlorodibenzo-p-dioxin. 3. Effects on spermatogenesis and reproductive capability
    • Mably T. A. Bjerke D. L. Moore R. W. Gendron-Fitzpatrick A. Peterson R. E. 1992a In utero and lactational exposure of male rats to 2,3,7,8- tetrachlorodibenzo-p-dioxin. 3. Effects on spermatogenesis and reproductive capability Toxicology and Applied Pharmacology 114 118 126
    • (1992) Toxicology and Applied Pharmacology , vol.114 , pp. 118-126
    • Mably, T.A.1    Bjerke, D.L.2    Moore, R.W.3    Gendron-Fitzpatrick, A.4    Peterson, R.E.5
  • 29
    • 0026755841 scopus 로고
    • In utero and lactational exposure of male rats to 2,3,7,8- tetrachlorodibenzo-p-dioxin. 2. Effects on sexual behavior and the regulation of luteinizing hormone secretion in adulthood
    • Mably T. A. Moore R. W. Goy R. W. Peterson R. E. 1992b In utero and lactational exposure of male rats to 2,3,7,8-tetrachlorodibenzo-p-dioxin. 2. Effects on sexual behavior and the regulation of luteinizing hormone secretion in adulthood Toxicology and Applied Pharmacology 114 108 117
    • (1992) Toxicology and Applied Pharmacology , vol.114 , pp. 108-117
    • Mably, T.A.1    Moore, R.W.2    Goy, R.W.3    Peterson, R.E.4
  • 30
    • 0026736617 scopus 로고
    • In utero and lactational exposure of male rats to 2,3,7,8- tetrachlorodibenzo-p-dioxin. 1. Effects on androgenic status
    • Mably T. A. Moore R. W. Peterson R. E. 1992c In utero and lactational exposure of male rats to 2,3,7,8-tetrachlorodibenzo-p-dioxin. 1. Effects on androgenic status Toxicology and Applied Pharmacology 114 97 107
    • (1992) Toxicology and Applied Pharmacology , vol.114 , pp. 97-107
    • Mably, T.A.1    Moore, R.W.2    Peterson, R.E.3
  • 31
    • 0035883851 scopus 로고    scopus 로고
    • 7,12-Dimethylbenz[a]anthracene inhibition of steroid production in MA-10 mouse Leydig tumor cells is not directly linked to induction of CYP1B1
    • Mandal P. K. McDaniel L. R. Prough R. A. Clark B. J. 2001 7,12-Dimethylbenz[a]anthracene inhibition of steroid production in MA-10 mouse Leydig tumor cells is not directly linked to induction of CYP1B1 Toxicology and Applied Pharmacology 175 200 208
    • (2001) Toxicology and Applied Pharmacology , vol.175 , pp. 200-208
    • Mandal, P.K.1    McDaniel, L.R.2    Prough, R.A.3    Clark, B.J.4
  • 32
    • 0023131239 scopus 로고
    • Depression of rat testicular 17-hydroxylase and 17,20-lyase after administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
    • Mebus C. A. Reddy V. R. Piper W. N. 1987 Depression of rat testicular 17-hydroxylase and 17,20-lyase after administration of 2,3,7,8- tetrachlorodibenzo-p-dioxin (TCDD) Biochemical Pharmacology 36 727 731
    • (1987) Biochemical Pharmacology , vol.36 , pp. 727-731
    • Mebus, C.A.1    Reddy, V.R.2    Piper, W.N.3
  • 34
    • 0025909716 scopus 로고
    • 2,3,7,8-Tetrachlorodibenzo-p-dioxin inhibits steroidogenesis in the rat testis by inhibiting the mobilization of cholesterol to cytochrome P450scc
    • Moore R. W. Jefcoate C. R. Peterson R. E. 1991 2,3,7,8- Tetrachlorodibenzo-p-dioxin inhibits steroidogenesis in the rat testis by inhibiting the mobilization of cholesterol to cytochrome P450scc Toxicology and Applied Pharmacology 109 85 97
    • (1991) Toxicology and Applied Pharmacology , vol.109 , pp. 85-97
    • Moore, R.W.1    Jefcoate, C.R.2    Peterson, R.E.3
  • 35
    • 0025143320 scopus 로고
    • A modification of a protein-binding method for rapid quantification of cAMP in cell-culture supernatants and body fluid
    • Nordstedt C. Fredholm B. B. 1990 A modification of a protein-binding method for rapid quantification of cAMP in cell-culture supernatants and body fluid Analytical Biochemistry 189 231 234
    • (1990) Analytical Biochemistry , vol.189 , pp. 231-234
    • Nordstedt, C.1    Fredholm, B.B.2
  • 36
    • 17744400089 scopus 로고    scopus 로고
    • Maternal exposure to a low dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) suppressed the development of reproductive organs of male rats: Dose-dependent increase of mRNA levels of 5a-reductase type 2 in contrast to decrease of androgen receptor in the pubertal ventral prostate
    • Ohsako S. Miyabara Y. Nishimura N. Kurosawa S. Sakaue M. Ishimura R. et al. 2001 Maternal exposure to a low dose of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) suppressed the development of reproductive organs of male rats: dose-dependent increase of mRNA levels of 5a-reductase type 2 in contrast to decrease of androgen receptor in the pubertal ventral prostate Toxicological Sciences 60 132 143
    • (2001) Toxicological Sciences , vol.60 , pp. 132-143
    • Ohsako, S.1    Miyabara, Y.2    Nishimura, N.3    Kurosawa, S.4    Sakaue, M.5    Ishimura, R.6
  • 37
    • 0036208501 scopus 로고    scopus 로고
    • Developmental stage-specific effects of perinatal 2,3,7,8- tetrachlorodibenzo-p-dioxin exposure on reproductive organs of male rat offspring
    • Ohsako S. Miyabara Y. Sakaue M. Ishimura R. Kakeyama M. Izumi H. Yonemoto J. Tohyama C. 2002 Developmental stage-specific effects of perinatal 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure on reproductive organs of male rat offspring Toxicological Sciences 66 283 292
    • (2002) Toxicological Sciences , vol.66 , pp. 283-292
    • Ohsako, S.1    Miyabara, Y.2    Sakaue, M.3    Ishimura, R.4    Kakeyama, M.5    Izumi, H.6    Yonemoto, J.7    Tohyama, C.8
  • 39
    • 0028588925 scopus 로고
    • Short-term toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in laboratory animals: Effects, mechanisms, and animal models
    • Pohjanvirta R. Tuomisto J. 1994 Short-term toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in laboratory animals: effects, mechanisms, and animal models Pharmacological Reviews 46 483 549
    • (1994) Pharmacological Reviews , vol.46 , pp. 483-549
    • Pohjanvirta, R.1    Tuomisto, J.2
  • 40
  • 41
    • 0028849927 scopus 로고
    • In utero and lactational exposure of the male rat to 2,3,7,8- tetrachlorodibenzo-p-dioxin: Impaired prostate growth and development without inhibited androgen production
    • Roman B. L. Sommer R. J. Shinomiya K. Peterson R. E. 1995 In utero and lactational exposure of the male rat to 2,3,7,8-tetrachlorodibenzo-p-dioxin: impaired prostate growth and development without inhibited androgen production Toxicology and Applied Pharmacology 134 241 250
    • (1995) Toxicology and Applied Pharmacology , vol.134 , pp. 241-250
    • Roman, B.L.1    Sommer, R.J.2    Shinomiya, K.3    Peterson, R.E.4
  • 42
    • 0010417886 scopus 로고    scopus 로고
    • Responsiveness of the adult male rat reproductive tract to 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure: Ah receptor and ARNT expression, CYP1A1 induction, and Ah receptor down-regulation
    • Roman B. L. Pollenz R. S. Peterson R. E. 1998 Responsiveness of the adult male rat reproductive tract to 2,3,7,8-tetrachlorodibenzo-p-dioxin exposure: Ah receptor and ARNT expression, CYP1A1 induction, and Ah receptor down-regulation Toxicology and Applied Pharmacology 150 228 239
    • (1998) Toxicology and Applied Pharmacology , vol.150 , pp. 228-239
    • Roman, B.L.1    Pollenz, R.S.2    Peterson, R.E.3
  • 43
    • 0025899116 scopus 로고
    • Human chorionic gonadotropin treatment prevents depressed 17 alpha-hydroxylase/C17-20 lyase activities and serum testosterone concentrations in 2,3,7,8-tetrachlorodibenzo-p-dioxin-treated rats
    • Ruangwises S. Bestervelt L. L. Piper D. W. Nolan C. J. Piper W. N. 1991 Human chorionic gonadotropin treatment prevents depressed 17 alpha-hydroxylase/C17-20 lyase activities and serum testosterone concentrations in 2,3,7,8-tetrachlorodibenzo-p-dioxin-treated rats Biology of Reproduction 45 143 150
    • (1991) Biology of Reproduction , vol.45 , pp. 143-150
    • Ruangwises, S.1    Bestervelt, L.L.2    Piper, D.W.3    Nolan, C.J.4    Piper, W.N.5
  • 44
    • 0025942027 scopus 로고
    • Morphological and histochemical pattern of response in rat testes after administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)
    • Rune G. M. de Souza P. Krowke R. Merker H. J. Neubert D. 1991 Morphological and histochemical pattern of response in rat testes after administration of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) Histology and Histopathology 6 459 467
    • (1991) Histology and Histopathology , vol.6 , pp. 459-467
    • Rune, G.M.1    De Souza, P.2    Krowke, R.3    Merker, H.J.4    Neubert, D.5
  • 45
    • 0032102432 scopus 로고    scopus 로고
    • Treatment of rats during pubertal development with 2,3,7,8- tetrachlorodibenzo-p-dioxin alters both signaling kinase activities and epidermal growth factor receptor binding in the testis and the motility and acrosomal reaction of sperm
    • el Sabeawy F. Wang S. Overstreet J. Miller M. Lasley B. Enan E. 1998 Treatment of rats during pubertal development with 2,3,7,8-tetrachlorodibenzo-p- dioxin alters both signaling kinase activities and epidermal growth factor receptor binding in the testis and the motility and acrosomal reaction of sperm Toxicology and Applied Pharmacology 150 427 442
    • (1998) Toxicology and Applied Pharmacology , vol.150 , pp. 427-442
    • El Sabeawy, F.1    Wang, S.2    Overstreet, J.3    Miller, M.4    Lasley, B.5    Enan, E.6
  • 46
    • 0037370164 scopus 로고    scopus 로고
    • Expression of aryl hydrocarbon receptor and aryl hydrocarbon receptor nuclear translocator messenger ribonucleic acids and proteins in rat and human testis
    • Schultz R. Suominen J. Varre T. Hakovirta H. Parvinen M. Toppari J. Pelto-Huikko M. 2003 Expression of aryl hydrocarbon receptor and aryl hydrocarbon receptor nuclear translocator messenger ribonucleic acids and proteins in rat and human testis Endocrinology 144 767 776
    • (2003) Endocrinology , vol.144 , pp. 767-776
    • Schultz, R.1    Suominen, J.2    Varre, T.3    Hakovirta, H.4    Parvinen, M.5    Toppari, J.6    Pelto-Huikko, M.7
  • 47
    • 3242789451 scopus 로고    scopus 로고
    • Pattern of male reproductive system effects after in utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure in three differentially TCDD-sensitive rat lines
    • Simanainen U. Haavisto T. Tuomisto J.T. Paranko J. Toppari J. Tuomisto J. Peterson R.E. Viluksela M. 2004 Pattern of male reproductive system effects after in utero and lactational 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure in three differentially TCDD-sensitive rat lines Toxicological Sciences 80 101 108
    • (2004) Toxicological Sciences , vol.80 , pp. 101-108
    • Simanainen, U.1    Haavisto, T.2    Tuomisto, J.T.3    Paranko, J.4    Toppari, J.5    Tuomisto, J.6    Peterson, R.E.7    Viluksela, M.8
  • 48
    • 0021735168 scopus 로고
    • Rat testicular endogenous steroids and number of Leydig cells between the fetal period and sexual maturity
    • Tapanainen J. Kuopio T. Pelliniemi L. J. Huhtaniemi I. 1984 Rat testicular endogenous steroids and number of Leydig cells between the fetal period and sexual maturity Biology of Reproduction 31 1027 1035
    • (1984) Biology of Reproduction , vol.31 , pp. 1027-1035
    • Tapanainen, J.1    Kuopio, T.2    Pelliniemi, L.J.3    Huhtaniemi, I.4
  • 49
    • 0031194864 scopus 로고    scopus 로고
    • In utero and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin: Effects on development of the male and female reproductive system of the mouse
    • Theobald H. M. Peterson R. E. 1997 In utero and lactational exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin: effects on development of the male and female reproductive system of the mouse Toxicology and Applied Pharmacology 145 124 135
    • (1997) Toxicology and Applied Pharmacology , vol.145 , pp. 124-135
    • Theobald, H.M.1    Peterson, R.E.2
  • 50
    • 0034523380 scopus 로고    scopus 로고
    • 2,3,7,8-tetrachlorodibenzo-p-dioxin inhibits luminal cell differentiation and androgen responsiveness of the ventral prostate without inhibiting prostatic 5α-dihydrotestosterone formation or testicular androgen production in rat offspring
    • Theobald H. Michael R. Beth L. Lin T. M. Ohtani S. Chen S. W. Peterson R. E. 2000 2,3,7,8-tetrachlorodibenzo-p-dioxin inhibits luminal cell differentiation and androgen responsiveness of the ventral prostate without inhibiting prostatic 5α-dihydrotestosterone formation or testicular androgen production in rat offspring Toxicological Sciences 58 324 338
    • (2000) Toxicological Sciences , vol.58 , pp. 324-338
    • Theobald, H.1    Michael, R.2    Beth, L.3    Lin, T.M.4    Ohtani, S.5    Chen, S.W.6    Peterson, R.E.7
  • 51
    • 0036300445 scopus 로고    scopus 로고
    • 2,3,7,8-tetrachlorodibenzo-p-dioxin interacts with endogenous estradiol to disrupt prostate gland morphogenesis in male rat fetuses
    • Timms B. G. Peterson R. E. vom Saal F. S. 2002 2,3,7,8- tetrachlorodibenzo-p-dioxin interacts with endogenous estradiol to disrupt prostate gland morphogenesis in male rat fetuses Toxicological Sciences 67 264 274
    • (2002) Toxicological Sciences , vol.67 , pp. 264-274
    • Timms, B.G.1    Peterson, R.E.2    Vom Saal, F.S.3
  • 52
    • 0028928891 scopus 로고
    • Human chorionic gonadotropin protects Leydig cell function against 2,3,7,8-tetrachlorodibenzo-p-dioxin in adult rats: Role of Leydig cell cytoplasmic volume
    • Wilker C. E. Welsh S. Jr. Stephen H. Narasimhan T. R. Johnson L 1995 Human chorionic gonadotropin protects Leydig cell function against 2,3,7,8-tetrachlorodibenzo-p-dioxin in adult rats: role of Leydig cell cytoplasmic volume Toxicology 95 93 102
    • (1995) Toxicology , vol.95 , pp. 93-102
    • Wilker, C.E.1    Welsh Jr., S.2    Stephen, H.3    Narasimhan, T.R.4    Johnson, L.5
  • 53
    • 0030296968 scopus 로고    scopus 로고
    • Effects of developmental exposure to indole-3-carbinol or 2,3,7,8-tetrachlorodibenzo-p-dioxin on reproductive potential of male rat offspring
    • Wilker C. Johnson L. Safe S. 1996 Effects of developmental exposure to indole-3-carbinol or 2,3,7,8-tetrachlorodibenzo-p-dioxin on reproductive potential of male rat offspring Toxicology and Applied Pharmacology 141 68 75
    • (1996) Toxicology and Applied Pharmacology , vol.141 , pp. 68-75
    • Wilker, C.1    Johnson, L.2    Safe, S.3
  • 54
    • 0347481466 scopus 로고    scopus 로고
    • Characteristic expression of aryl hydrocarbon receptor repressor gene in human tissues: Organ-specific distribution and variable induction patterns in mononuclear cells
    • Yamamoto J. Ihara K. Nakayama H. Hikino S. Satoh K. Kubo N. Iida T. Fujii Y. Hara T. 2004 Characteristic expression of aryl hydrocarbon receptor repressor gene in human tissues: organ-specific distribution and variable induction patterns in mononuclear cells Life Sciences 74 1039 1049
    • (2004) Life Sciences , vol.74 , pp. 1039-1049
    • Yamamoto, J.1    Ihara, K.2    Nakayama, H.3    Hikino, S.4    Satoh, K.5    Kubo, N.6    Iida, T.7    Fujii, Y.8    Hara, T.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.