Pkn is a novel partner of cyclin T2a in muscle differentiation

Journal of Cellular Physiology

Volumn 207, Issue 1, 2006, Pages 232-237

  Cottone, Giuliano ^a   Baldi, Alfonso ^a,b   Palescandolo, Emanuele ^a   Manente, Lucrezia ^a   Penta, Roberta ^b   Paggi, Marco G ^a   De Luca, Antonio ^a,b  

^a REGINA ELENA NATIONAL CANCER INSTITUTE   (Italy)

^b SECOND UNIVERSITY OF NAPLES   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN T2A; CYCLINE; LUCIFERASE; MYOD PROTEIN; MYOGENIN; MYOSIN HEAVY CHAIN; PROTEIN PKNALPHA; PROTEIN SERINE THREONINE KINASE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ASSAY; CATALYSIS; CELL CULTURE; CELL DIFFERENTIATION; CELL STRAIN 3T3; CULTURE MEDIUM; DNA LIBRARY; GENETIC TRANSCRIPTION; GENETIC TRANSFECTION; IMMUNOPRECIPITATION; MOUSE; MUSCLE DEVELOPMENT; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; STARVATION; TWO HYBRID SYSTEM; YEAST;

ANIMALS; BINDING SITES; BINDING, COMPETITIVE; CELL DIFFERENTIATION; CELL LINE; CYCLIN-DEPENDENT KINASE 9; CYCLINS; DNA, COMPLEMENTARY; GENE EXPRESSION; HUMANS; MICE; MUSCLE CELLS; MUTATION; MYOD PROTEIN; MYOGENIN; MYOSIN HEAVY CHAINS; NIH 3T3 CELLS; PLASMIDS; PROTEIN BINDING; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; RECOMBINANT PROTEINS; SACCHAROMYCES CEREVISIAE; TRANSFECTION; TWO-HYBRID SYSTEM TECHNIQUES;

ANIMALIA;

EID: 33644880875     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.20566     Document Type: Article

References (19)

1. Bagella L, MacLachlan TK, Buono RJ, Pisano MM, Giordano A, De Luca A. 1998. Cloning of murine CDK9/PITALRE and its tissue-specific expression in development. J Cell Physiol 177:206-213.
2. De Luca A, Tosolini A, Russo P, Severino A, Baldi A, De Luca L, Cavallotti I, Baldi F, Giordano A, Testa JR, Paggi MG. 2001a. Cyclin T2a gene maps on human chromosome 2q21. J Histochem Cytochem 49:693-698.
3. De Luca A, Russo P, Severino A, Baldi A, Battista T, Cavallotti I, De Luca L, Baldi F, Giordano A, Paggi MG. 2001b. Pattern of expression of cyclin T1 in human tissues. J Histochem Cytochem 49:685-692.
4. De Luca A, De Falco M, Baldi A, Paggi MG. 2003. Cyclin T: Three forms for different roles in physiological and pathological functions. J Cell Physiol 194: 101-107.
5. Garriga J, Peng J, Parreno M, Price DH, Henderson EE, Graña X. 1998. Upregulation of cyclin T1/cdk9 complexes during T cell activation. Oncogene 17:3093-3102.
6. Grana X, Reddy EP. 1995. Cell cycle control in mammalian cells: Role of cyclins, cyclin dependent kinases (CDKs), growth suppressor genes and cyclin-dependent kinase inhibitors. Oncogene 11:211-219.
7. Grapa X, De Luca A, Sang N, Fu Y, Claudio PP, Rosenblatt J, Morgan DO, Giordano A. 1994. PITALRE, a nuclear CDC2-related protein kinase that phosphorylates the retinoblastoma protein in vitro. Proc Natl Acad Sci USA 91:3834-3838.
8. MacLellan WR, Schneider MD. 2000. Genetic dissection of cardiac growth control pathways. Annu Rev Physiol 62:289-320.
9. Morissette MR, Sah VP, Glembotski CC, Brown JH. 2000. The Rho effector, PKN, regulates ANF gene transcription in cardiomyocytes through a serum response element. Am J Physiol Heart Circ Physiol 278:H1769-H1774.
10. Mukai H. 2003. The structure and function of PKN, a protein kinase having a catalytic homologous to that of PKC. J Biochem 133:17-27.
11. Mukai H, Miyahara M, Sunakawa H, Shibata H, Toshimori M, Kitagawa M, Shimakawa M, Takanaga H, Ono Y. 1996. Translocation of PKN from the cytosol to the nucleus induced by stresses. Proc Nat Acad Sci 93:10195-10199.
12. Peng J, Zhu Y, Milton JT, Price DH. 1998. Identification of multiple cyclin subunits of human P-TEFb. Genes Dev 12:755-762.
13. Ping YH, Rana TM. 1999. Tat-associated kinase (P-TEFb): A component of transcription preinitiation and elongation complexes. J Biol Chem 274:7399-7404.
14. Sang N, Condorelli G, De Luca A, MacLachlan K, Giordano A. 1996. Generation of site directed mutagenesis by extralong, high-fidelity polymerase chain reaction analytical. Biochemistry 233:142-144.
15. Sano M, Abdellatif M, Oh H, Xie M, Bagella L, Giordano A, Michael LH, DeMajo FJ, Schneider MD. 2002. Activation and function of cyclin T-cdk9 (positive transcription elongation factor-b) in cardiac muscle-cell hypertrophy. Nature Med 8(11):1310-1317.
16. Sherr CS. 1996. Cancer cell cycles. Science 274:1672-1677.
17. Shibata H, Oda H, Mukai H, Oishi K, Misaki K, Ohkubo H, Ono Y. 1999. Interaction of PKN with a neuron-specific basic Helix-Loop-Helix transcription factor, NDRF/NeuroD2. Mol Brain Res 74:126, 134.
18. Simone C, Stiegler P, Bagella L, Pucci B, Bellan C, De Falco G, De Luca A, Guanti G, Puri PL, Giordano A. 2002. Activation of MyoD dependent transcription by CDK9/Cyclin T2. Oncogene 21:4137-4148.
19. Sordella R, Jiang W, Chen GC, Curto M, Settleman J. 2003. Modulation of Rho GTPase signaling regulates a switch between adipogenesis and myogenesis. Cell 113:147-158.