Computational design and experimental testing of a novel axial flow LVAD

ASAIO Journal

Volumn 51, Issue 6, 2005, Pages 702-710

  Untaroiu, Alexandrina ^a   Wood, Houston G ^a   Allaire, Paul E ^a   Throckmorton, Amy L ^b   Day, Steven ^c   Patel, Sonna M ^b   Ellman, Peter ^d   Tribble, Curt ^d   Olsen, Don B ^e  

^a University of Virginia   (United States)

^b University of Virginia   (United States)

^c Kate Gleason College of Engineering   (United States)

^d UNIVERSITY OF VIRGINIA   (United States)

^e Utah Artificial Heart Institute   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BODY FLUIDS; CARDIOLOGY; COMPUTATIONAL FLUID DYNAMICS; IMPLANTS (SURGICAL); NUMERICAL METHODS;

ANIMAL IMPLANTATIONS; DESTINATION THERAPY; STAGNANT FLOW; VENTRICULAR ASSIST DEVICE;

BIOMEDICAL EQUIPMENT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ASSISTED CIRCULATION; BLOOD FLOW; COMPUTATIONAL FLUID DYNAMICS; CONTROLLED STUDY; HEART FAILURE; HEART LEFT VENTRICLE PRESSURE; HYDRAULIC CONDUCTIVITY; IMPLANT; INTERMETHOD COMPARISON; LONG TERM CARE; NONHUMAN; ANIMAL; BIOMEDICAL ENGINEERING; BLOOD RHEOLOGY; COMPARATIVE STUDY; CONGESTIVE HEART FAILURE; EVALUATION; HEART ASSIST DEVICE; HUMAN; MECHANICAL STRESS; PATHOPHYSIOLOGY; PROSTHESIS; SHEEP; SWINE;

PLASTIC;

ANIMALS; BIOMEDICAL ENGINEERING; HEART FAILURE, CONGESTIVE; HEART-ASSIST DEVICES; HEMORHEOLOGY; HUMANS; PLASTICS; PROSTHESIS DESIGN; SHEEP; STRESS, MECHANICAL; SWINE;

EID: 33644876647     PISSN: 10582916     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.mat.0000186126.21106.27     Document Type: Article

References (37)

1. American Heart Association: Heart Disease and Stroke Statistics: 2005 Update. Dallas, TX, American Heart Association, 2005.
2. Hunt S, Frazier OH: Mechanical circulatory support and cardiac transplantation. Circulation 97: 2079-2090, 1998.
3. Berne R, Levy MN: Physiology, 4th ed. St. Louis, Mosby Electronic Production, 1998.
4. Goldstein D, Oz M: Cardiac Assist Devices. New York, Future Publishing Company, 2000.
5. Funk D: Epidemiology of end-stage heart disease, in Committee to Evaluate the Artificial Heart Program of the National Heart, Lung, and Blood Institute. The Artificial Heart: Prototypes, Policies, and Patients, Washington, DC, National Academy Press, 1991.
6. Song X, Untaroiu A, Wood HG, et al: Design and transient CFD study of a continuous axial flow ventricular assist device. ASAIO J 50: 215-224, 2004.
7. Untaroiu A, Throckmorton AL, Patel SM, et al: Numerical and experimental analysis of an axial flow LVAD: The influence of the diffuser on the overall pump performance. J Artif Organs 29: 581-591, 2005.
8. Song X, Throckmorton AL, Untaroiu A, et al: Axial flow blood pumps. ASAIO J 49: 355-364, 2003.
9. Allaire P, Wood HG, Award RS, Olsen DB: Blood flow in a continuous flow ventricular assist device. Artif Organs 23: 769-773, 1999.
10. Baloh M, Allaire PE, Hilton EF, et al: Characterization of a magnetic bearing system and fluid properties for a continuous flow ventricular assist device. Artif Organs 23: 792-796, 1999.
11. Hilton E, Allaire PE, Baloh MJ, et al: Test controller design, implementation, and performance for a magnetic suspension continuous flow ventricular assist device. Artif Organs 23: 785-791, 1999.
12. Day S, McDaniel JC, Curtas A, et al: Optical measurements of blood velocity and shear in HeartQuest LVAD [Abstract]. ASAIO J 46:188, 2000.
13. Anderson J, Wood HG, Allaire PE, Olsen DB: Numerical analysis of blood flow in the clearance regions of a continuous flow artificial heart pump. Artif Organs 24: 492-500, 2000.
14. Anderson J, Wood HG, Allaire PE, et al: Numerical studies of blood shear and washing in a continuous flow ventricular assist device. ASAIO J 46: 486-494, 2000.
15. Curtas A, Wood HG, Allaire PE, et al: CFD Modeling of impeller designs for the HeartQuest™ LVAD. ASAIO J 48: 552-561, 2002.
16. Burgreen G, Antaki JF, Wu ZJ, Holmes AJ: Computational fluid dynamics as a development tool for rotary blood pumps. Artif Organs 25: 336-340, 2001.
17. Masuzawa T, Tsukiya T, Endo S, et al: Development of design methods for a centrifugal blood pump with a fluid dynamic approach: Results in hemolysis tests. Artif Organs 23: 757-761, 1999.
18. Miyazoe Y, Sawairi T, Ito K, et al: Computational fluid dynamics to establish the design process of a centrifugal blood pump: Second report. Artif Organs 23: 762-768, 1999.
19. Takiura K, Masuzawa T, Endo S, et al: Development of design methods of a centrifugal blood pump with in vitro test, flow visualization, and computational fluid dynamics: Result in hemolysis tests. Artif Organs 22: 393-398, 1998.
20. Stepanoff A: Centrifugal and Axial Flow Pumps. 2nd ed. New York, Krieger Publishing Company, 1957.
21. Anderson J, Wood HG, Allaire PE, et al: Computational flow study of the Cfvad 3 blood pump. Artif Organs 24: 377-385, 2000.
22. Song X, Wood HG, Olsen DB: CFD study of the 4th generation prototype of a continuous flow ventricular assist device. J Biomech Eng 126: 180-187, 2004.
23. Bludszuweit C: Model for general mechanical blood damage prediction. Artif Organs 19: 583-589, 1995.
24. Bludszuweit C: Three-dimensional numerical prediction of stress loading of blood particles in a centrifugal pump. Artif Organs 19: 590-596, 1995.
25. Kim W, Jo YH, Min BG, Won TH: Implantation of one piece biventricular assist device by left thoracotomy in an ovine model. Artif Organs 24: 760-763, 2000.
26. Nojiri C, Kijima T, Maekawa J: Recent progress in the development of Terumo implantable left ventricular assist system. ASAIO J 45: 199-203, 1999.
27. Nojiri C, Kijima T, Maekawa J: Terumo implantable left ventricular assist system: Results of long-term animal study. ASAIO J 46: 117-122, 2000.
28. Shum-Tim D, Duncan BW, Hraska V: Evaluation of a pulsatile pediatric ventricular assist device in an acute right heart failure model. Ann Thoracic Surg 64: 1374-1380, 1997.
29. Van der Meer A, James NL, Edwards GA: Initial in vivo experience of the VentrAssist implantable rotary blood pump in sheep. Artif Organs 27: 21-26, 1997.
30. Westaby S, Katsumata T, Houel R: Jarvik 2000 heart: potential for bridge to myocyte recovery. Circulation 98: 1568-1574, 1998.
31. Yamada T, Nishimura K, Akamatsu T: In vivo testing of a magnetically suspended centrifugal pump designed for long-term use. Int J Artif Organs 20: 562-569, 1997.
32. Zietkiewicz M, Perek B, Meyns B: Chronic heart failure model induced by coronary embolization in sheep. Int J Artif Organs 22: 499-504, 1999.
33. Apel J, Neudel F, Reul H: Computational fluid dynamics and experimental validation of a microaxial blood pump. ASAIO J 47: 552-558, 2001.
34. Sallam A, Hwang NC: Human red cell hemolysis in a turbulent shear flow: contribution of Reynolds shear stresses. Biorheology 21: 783-797, 1984.
35. Grigioni M, Daniele C, D'Avenio, G, Barbaro V: A discussion on the threshold limit for hemolysis related to Reynolds shear stress. J Biomech 32: 1107-1112, 1999.
36. Grigioni M, Daniele C, D'Avenio, G, Barbaro V: On the monodimensional approach to the estimation of the highest Reynolds shear stress in a turbulent flow. J Biomech 33: 701-708, 2000.
37. Day SW, McDaniel JC: PIV measurements of flow in a centrifugal blood pump: Time-varying flow. J Biomech Eng 127: 254-263, 2005.