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Volumn 6, Issue 3, 2005, Pages 200-207

Risk stratification of patients with newly dignosed multiple myeloma: Optimizing treatment based on pretreatment characteristics

Author keywords

Dexamethasone; International staging system; Melphalan; Prognostic factors; Stem cell transplantation

Indexed keywords

BORTEZOMIB; DEXAMETHASONE; DOXORUBICIN; LENALIDOMIDE; MELPHALAN; PREDNISONE; THALIDOMIDE; VINCRISTINE;

EID: 33644874173     PISSN: 15579190     EISSN: None     Source Type: Journal    
DOI: 10.3816/CLM.2005.n.047     Document Type: Review
Times cited : (6)

References (94)
  • 2
    • 12944271053 scopus 로고    scopus 로고
    • Cancer statistics, 2005
    • [Erratum in: CA Cancer J Clin 2005; 55:259]
    • Jemal A, Murray T, Ward E, et al. Cancer statistics, 2005. CA Cancer J Clin 2005; 55:10-30 [Erratum in: CA Cancer J Clin 2005; 55:259].
    • (2005) CA Cancer J Clin , vol.55 , pp. 10-30
    • Jemal, A.1    Murray, T.2    Ward, E.3
  • 3
    • 0034758836 scopus 로고    scopus 로고
    • The clinical significance of cytogenetic abnormalities in acute myeloid leukaemia
    • Grimwade D. The clinical significance of cytogenetic abnormalities in acute myeloid leukaemia. Best Pract Res Clin Haematol 2001; 14:497-529.
    • (2001) Best Pract Res Clin Haematol , vol.14 , pp. 497-529
    • Grimwade, D.1
  • 4
    • 0036344108 scopus 로고    scopus 로고
    • Cytogenetics and molecular genetics of acute lymphoblastic leukemia
    • Harrison CJ, Foroni L. Cytogenetics and molecular genetics of acute lymphoblastic leukemia. Rev Clin Exp Hematol 2002; 6:91-113.
    • (2002) Rev Clin Exp Hematol , vol.6 , pp. 91-113
    • Harrison, C.J.1    Foroni, L.2
  • 5
    • 0029155618 scopus 로고
    • International Prognostic Index for aggressive non-Hodgkin's lymphoma is valid for all malignancy grades
    • Hermans J, Krol AD, van Groningen K, et al. International Prognostic Index for aggressive non-Hodgkin's lymphoma is valid for all malignancy grades. Blood 1995; 86:1460-1463.
    • (1995) Blood , vol.86 , pp. 1460-1463
    • Hermans, J.1    Krol, A.D.2    van Groningen, K.3
  • 6
    • 4444326818 scopus 로고    scopus 로고
    • Follicular lymphoma international prognostic index
    • Solal-Celigny P, Roy P, Colombat P, et al. Follicular lymphoma international prognostic index. Blood 2004; 104:1258-1265.
    • (2004) Blood , vol.104 , pp. 1258-1265
    • Solal-Celigny, P.1    Roy, P.2    Colombat, P.3
  • 7
    • 23644455476 scopus 로고    scopus 로고
    • Drug therapy for acute myeloid leukemia
    • Tallman MS, Gilliland DG, Rowe JM. Drug therapy for acute myeloid leukemia. Blood 2005; 106:1154-1163.
    • (2005) Blood , vol.106 , pp. 1154-1163
    • Tallman, M.S.1    Gilliland, D.G.2    Rowe, J.M.3
  • 8
    • 22044440425 scopus 로고    scopus 로고
    • Cyclin D dysregulation: An early and unifying pathogenic event in multiple myeloma
    • Bergsagel PL, Kuehl WM, Zhan F, et al. Cyclin D dysregulation: an early and unifying pathogenic event in multiple myeloma. Blood 2005; 106:296-303.
    • (2005) Blood , vol.106 , pp. 296-303
    • Bergsagel, P.L.1    Kuehl, W.M.2    Zhan, F.3
  • 9
    • 10744223381 scopus 로고    scopus 로고
    • Genetics and cytogenetics of multiple myeloma: A workshop report
    • Fonseca R, Barlogie B, Bataille R, et al. Genetics and cytogenetics of multiple myeloma: a workshop report. Cancer Res 2004; 64:1546-1558.
    • (2004) Cancer Res , vol.64 , pp. 1546-1558
    • Fonseca, R.1    Barlogie, B.2    Bataille, R.3
  • 10
    • 20944437020 scopus 로고    scopus 로고
    • Gene expression profiling of plasma cell dyscrasias reveals molecular patterns associated with distinct IGH translocations in multiple myeloma
    • Mattioli M, Agnelli L, Fabris S, et al. Gene expression profiling of plasma cell dyscrasias reveals molecular patterns associated with distinct IGH translocations in multiple myeloma. Oncogene 2005; 24:2461-2473.
    • (2005) Oncogene , vol.24 , pp. 2461-2473
    • Mattioli, M.1    Agnelli, L.2    Fabris, S.3
  • 11
    • 20644460600 scopus 로고    scopus 로고
    • International staging system for multiple myeloma
    • Greipp PR, San Miguel J, Durie BG, et al. International staging system for multiple myeloma. J Clin Oncol 2005; 23:3412-3420.
    • (2005) J Clin Oncol , vol.23 , pp. 3412-3420
    • Greipp, P.R.1    San Miguel, J.2    Durie, B.G.3
  • 12
    • 0016804136 scopus 로고
    • A clinical staging system for multiple myeloma: Correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival
    • Durie BG, Salmon SE. A clinical staging system for multiple myeloma: correlation of measured myeloma cell mass with presenting clinical features, response to treatment, and survival. Cancer 1975; 36:842-854.
    • (1975) Cancer , vol.36 , pp. 842-854
    • Durie, B.G.1    Salmon, S.E.2
  • 13
    • 0020973430 scopus 로고
    • Serum beta2 microglobulin and survival duration in multiple myeloma: A simple reliable marker for staging
    • Bataille R, Durie BG, Grenier J. Serum beta2 microglobulin and survival duration in multiple myeloma: a simple reliable marker for staging. Br J Haematol 1983; 55:439-447.
    • (1983) Br J Haematol , vol.55 , pp. 439-447
    • Bataille, R.1    Durie, B.G.2    Grenier, J.3
  • 14
    • 0025178669 scopus 로고
    • Prognostic value of pre-treatment serum beta 2 microglobulin in myeloma: A Southwest Oncology Group Study
    • Durie BG, Stock-Novack D, Salmon SE, et al. Prognostic value of pre-treatment serum beta 2 microglobulin in myeloma: a Southwest Oncology Group Study. Blood 1990; 75:823-830.
    • (1990) Blood , vol.75 , pp. 823-830
    • Durie, B.G.1    Stock-Novack, D.2    Salmon, S.E.3
  • 15
    • 0035869257 scopus 로고    scopus 로고
    • Chromosome 13 abnormalities identified by FISH analysis and serum beta2-microglobulin produce a powerful myeloma staging system for patients receiving high-dose therapy
    • Facon T, Avet-Loiseau H, Guillerm G, et al. Chromosome 13 abnormalities identified by FISH analysis and serum beta2-microglobulin produce a powerful myeloma staging system for patients receiving high-dose therapy. Blood 2001; 97:1566-1571.
    • (2001) Blood , vol.97 , pp. 1566-1571
    • Facon, T.1    Avet-Loiseau, H.2    Guillerm, G.3
  • 16
    • 0347815503 scopus 로고    scopus 로고
    • Single versus double autologous stem-cell transplantation for multiple myeloma
    • Attal M, Harousseau JL, Facon T, et al. Single versus double autologous stem-cell transplantation for multiple myeloma. N Engl J Med 2003; 349:2495-2502.
    • (2003) N Engl J Med , vol.349 , pp. 2495-2502
    • Attal, M.1    Harousseau, J.L.2    Facon, T.3
  • 17
    • 18544409610 scopus 로고    scopus 로고
    • Results of high-dose therapy for 1000 patients with multiple myeloma: Durable complete remissions and superior survival in the absence of chromosome 13 abnormalities
    • Desikan R, Barlogie B, Sawyer J, et al. Results of high-dose therapy for 1000 patients with multiple myeloma: durable complete remissions and superior survival in the absence of chromosome 13 abnormalities. Blood 2000; 95:4008-4010.
    • (2000) Blood , vol.95 , pp. 4008-4010
    • Desikan, R.1    Barlogie, B.2    Sawyer, J.3
  • 18
    • 0036162098 scopus 로고    scopus 로고
    • Predicting long-term (> or = 5 years) event-free survival in multiple myeloma patients following planned tandem autotransplants
    • Tricot G, Spencer T, Sawyer J, et al. Predicting long-term (> or = 5 years) event-free survival in multiple myeloma patients following planned tandem autotransplants. Br J Haematol 2002; 116:211-217.
    • (2002) Br J Haematol , vol.116 , pp. 211-217
    • Tricot, G.1    Spencer, T.2    Sawyer, J.3
  • 19
    • 0037217603 scopus 로고    scopus 로고
    • Prognostic impact of cytogenetic and interphase fluorescence in situ hybridization-defined chromosome 13 deletion in multiple myeloma: Early results of total therapy II
    • Shaughnessy J Jr, Tian E, Sawyer J, et al. Prognostic impact of cytogenetic and interphase fluorescence in situ hybridization-defined chromosome 13 deletion in multiple myeloma: early results of total therapy II. Br J Haematol 2003; 120:44-52.
    • (2003) Br J Haematol , vol.12 , pp. 44-52
    • Shaughnessy Jr., J.1    Tian, E.2    Sawyer, J.3
  • 20
    • 0029822773 scopus 로고    scopus 로고
    • Allogeneic marrow transplantation for multiple myeloma: An analysis of risk factors on outcome
    • Bensinger WI, Buckner CD, Anasetti C, et al. Allogeneic marrow transplantation for multiple myeloma: an analysis of risk factors on outcome. Blood 1996; 88:2787-2793.
    • (1996) Blood , vol.88 , pp. 2787-2793
    • Bensinger, W.I.1    Buckner, C.D.2    Anasetti, C.3
  • 21
    • 0029039069 scopus 로고
    • Prognostic factors in allogeneic bone marrow transplantation for multiple myeloma
    • Gahrton G, Tura S, Ljungman P, et al. Prognostic factors in allogeneic bone marrow transplantation for multiple myeloma. J Clin Oncol 1995; 13:1312-1322.
    • (1995) J Clin Oncol , vol.13 , pp. 1312-1322
    • Gahrton, G.1    Tura, S.2    Ljungman, P.3
  • 22
    • 0024557122 scopus 로고
    • High serum levels of lactic dehydrogenase identify a high-grade lymphoma-like myeloma
    • Barlogie B, Smallwood L, Smith T, et al. High serum levels of lactic dehydrogenase identify a high-grade lymphoma-like myeloma. Ann Intern Med 1989; 110:521-525.
    • (1989) Ann Intern Med , vol.110 , pp. 521-525
    • Barlogie, B.1    Smallwood, L.2    Smith, T.3
  • 23
    • 0026355691 scopus 로고
    • High serum lactate dehydrogenase level as a marker for drug resistance and short survival in multiple myeloma
    • Dimopoulos MA, Barlogie B, Smith TL, et al. High serum lactate dehydrogenase level as a marker for drug resistance and short survival in multiple myeloma. Ann Intern Med 1991; 115:931-935.
    • (1991) Ann Intern Med , vol.115 , pp. 931-935
    • Dimopoulos, M.A.1    Barlogie, B.2    Smith, T.L.3
  • 24
    • 0022650979 scopus 로고
    • Prognostic factors and staging in multiple myeloma: A reappraisal
    • Bataille R, Durie BG, Grenier J, et al. Prognostic factors and staging in multiple myeloma: a reappraisal. J Clin Oncol 1986; 4:80-87.
    • (1986) J Clin Oncol , vol.4 , pp. 80-87
    • Bataille, R.1    Durie, B.G.2    Grenier, J.3
  • 25
    • 0042128635 scopus 로고    scopus 로고
    • A new staging system for multiple myeloma patients based on the Southwest Oncology Group (SWOG) experience
    • Jacobson JL, Hussein MA, Barlogie B, et al. A new staging system for multiple myeloma patients based on the Southwest Oncology Group (SWOG) experience. Br J Haematol 2003; 122:441-450.
    • (2003) Br J Haematol , vol.122 , pp. 441-450
    • Jacobson, J.L.1    Hussein, M.A.2    Barlogie, B.3
  • 26
    • 0024832002 scopus 로고
    • Serum levels of interleukin 6, a potent myeloma cell growth factor, as a reflect of disease severity in plasma cell dyscrasias
    • Bataille R, Jourdan M, Zhang XG, et al. Serum levels of interleukin 6, a potent myeloma cell growth factor, as a reflect of disease severity in plasma cell dyscrasias. J Clin Invest 1989; 84:2008-2011.
    • (1989) J Clin Invest , vol.84 , pp. 2008-2011
    • Bataille, R.1    Jourdan, M.2    Zhang, X.G.3
  • 27
    • 0027164309 scopus 로고
    • Plasma cell labeling index and beta 2-microglobulin predict survival independent of thymidine kinase and C-reactive protein in multiple myeloma
    • Greipp PR, Lust JA, O'Fallon WM, et al. Plasma cell labeling index and beta 2-microglobulin predict survival independent of thymidine kinase and C-reactive protein in multiple myeloma. Blood 1993; 81:3382-3387.
    • (1993) Blood , vol.81 , pp. 3382-3387
    • Greipp, P.R.1    Lust, J.A.2    O'Fallon, W.M.3
  • 28
    • 0028899614 scopus 로고
    • A new staging system for multiple myeloma based on the number of S-phase plasma cells
    • San Miguel JF, Garcia-Sanz R, Gonzalez M, et al. A new staging system for multiple myeloma based on the number of S-phase plasma cells. Blood 1995; 85:448-455.
    • (1995) Blood , vol.85 , pp. 448-455
    • San Miguel, J.F.1    Garcia-Sanz, R.2    Gonzalez, M.3
  • 29
    • 0034930351 scopus 로고    scopus 로고
    • Laboratory correlates in multiple myeloma: How useful for prognosis?
    • Fonseca R, Conte G, Greipp PR. Laboratory correlates in multiple myeloma: how useful for prognosis? Blood Rev 2001; 15:97-102.
    • (2001) Blood Rev , vol.15 , pp. 97-102
    • Fonseca, R.1    Conte, G.2    Greipp, P.R.3
  • 30
    • 7244232591 scopus 로고    scopus 로고
    • Proliferative activity of plasma cells is the most relevant prognostic factor in elderly multiple myeloma patients
    • Garcia-Sanz R, Gonzalez-Fraile MI, Mateo G, et al. Proliferative activity of plasma cells is the most relevant prognostic factor in elderly multiple myeloma patients. Int J Cancer 2004; 112:884-889.
    • (2004) Int J Cancer , vol.112 , pp. 884-889
    • Garcia-Sanz, R.1    Gonzalez-Fraile, M.I.2    Mateo, G.3
  • 31
    • 0029814466 scopus 로고    scopus 로고
    • Peripheral blood monoclonal plasma cells as a predictor of survival in patients with multiple myeloma
    • Witzig TE, Gertz MA, Lust JA, et al. Peripheral blood monoclonal plasma cells as a predictor of survival in patients with multiple myeloma. Blood 1996; 88:1780-1787.
    • (1996) Blood , vol.88 , pp. 1780-1787
    • Witzig, T.E.1    Gertz, M.A.2    Lust, J.A.3
  • 32
    • 8244223868 scopus 로고    scopus 로고
    • Circulating plasma cells in multiple myeloma: Characterization and correlation with disease stage
    • Rawstron AC, Owen RG, Davies FE, et al. Circulating plasma cells in multiple myeloma: characterization and correlation with disease stage. Br J Haematol 1997; 97:46-55.
    • (1997) Br J Haematol , vol.97 , pp. 46-55
    • Rawstron, A.C.1    Owen, R.G.2    Davies, F.E.3
  • 33
    • 0029893342 scopus 로고    scopus 로고
    • Detection of myeloma cells in the peripheral blood by flow cytometry
    • Witzig TE, Kimlinger TK, Ahmann GJ, et al. Detection of myeloma cells in the peripheral blood by flow cytometry. Cytometry 1996; 26:113-120.
    • (1996) Cytometry , vol.26 , pp. 113-120
    • Witzig, T.E.1    Kimlinger, T.K.2    Ahmann, G.J.3
  • 34
    • 27144493396 scopus 로고    scopus 로고
    • Circulating plasma cells detected by flow cytometry as a predictor of survival in 302 patients with newly diagnosed multiple myeloma
    • Nowakowski GS, Witzig TE, Dingli D, et al. Circulating plasma cells detected by flow cytometry as a predictor of survival in 302 patients with newly diagnosed multiple myeloma. Blood 2005; 106:2276-2279.
    • (2005) Blood , vol.106 , pp. 2276-2279
    • Nowakowski, G.S.1    Witzig, T.E.2    Dingli, D.3
  • 35
    • 0032055938 scopus 로고    scopus 로고
    • Plasmablastic morphology-an independent prognostic factor with clinical and laboratory correlates: Eastern Cooperative Oncology Group (ECOG) myeloma trial E9486 report by the ECOG Myeloma Laboratory Group
    • Greipp PR, Leong T. Bennett JM, et al. Plasmablastic morphology-an independent prognostic factor with clinical and laboratory correlates: Eastern Cooperative Oncology Group (ECOG) myeloma trial E9486 report by the ECOG Myeloma Laboratory Group. Blood 1998; 91:2501-2507.
    • (1998) Blood , vol.91 , pp. 2501-2507
    • Greipp, P.R.1    Leong, T.2    Bennett, J.M.3
  • 36
    • 0032945928 scopus 로고    scopus 로고
    • Plasmablastic morphology is an independent predictor of poor survival after autologous stem-cell transplantation for multiple myeloma
    • Rajkumar SV, Fonseca R, Lacy MQ, et al. Plasmablastic morphology is an independent predictor of poor survival after autologous stem-cell transplantation for multiple myeloma. J Clin Oncol 1999; 17:1551-1557.
    • (1999) J Clin Oncol , vol.17 , pp. 1551-1557
    • Rajkumar, S.V.1    Fonseca, R.2    Lacy, M.Q.3
  • 37
    • 0032728111 scopus 로고    scopus 로고
    • Mature plasma cells as indicator of better prognosis in multiple myeloma. New methodology for the assessment of plasma cell morphology
    • Goasguen JE, Zandecki M, Mathiot C, et al. Mature plasma cells as indicator of better prognosis in multiple myeloma. New methodology for the assessment of plasma cell morphology. Leuk Res 1999; 23:1133-1140.
    • (1999) Leuk Res , vol.23 , pp. 1133-1140
    • Goasguen, J.E.1    Zandecki, M.2    Mathiot, C.3
  • 38
    • 0021792205 scopus 로고
    • The clinical significance of cytogenetic studies in 100 patients with multiple myeloma, plasma cell leukemia, or amyloidosis
    • Dewald GW, Kyle RA, Hicks CA, et al. The clinical significance of cytogenetic studies in 100 patients with multiple myeloma, plasma cell leukemia, or amyloidosis. Blood 1985; 66:380-390.
    • (1985) Blood , vol.66 , pp. 380-390
    • Dewald, G.W.1    Kyle, R.A.2    Hicks, C.A.3
  • 39
  • 40
    • 0032819014 scopus 로고    scopus 로고
    • Cytogenetic abnormalities correlate with the plasma cell labeling index and extent of bone marrow involvement in myeloma
    • Rajkumar SV, Fonseca R, Dewald GW, et al. Cytogenetic abnormalities correlate with the plasma cell labeling index and extent of bone marrow involvement in myeloma. Cancer Genet Cytogenet 1999; 113:73-77.
    • (1999) Cancer Genet Cytogenet , vol.113 , pp. 73-77
    • Rajkumar, S.V.1    Fonseca, R.2    Dewald, G.W.3
  • 41
    • 0032879477 scopus 로고    scopus 로고
    • Abnormal cytogenetics predict poor survival after high-dose therapy and autologous blood cell transplantation in multiple myeloma
    • Rajkumar S, Fonseca R, Lacy M, et al. Abnormal cytogenetics predict poor survival after high-dose therapy and autologous blood cell transplantation in multiple myeloma. Bone Marrow Transplant 1999; 24:497-503.
    • (1999) Bone Marrow Transplant , vol.24 , pp. 497-503
    • Rajkumar, S.1    Fonseca, R.2    Lacy, M.3
  • 42
    • 17144433568 scopus 로고    scopus 로고
    • Unique role of cytogenetics in the prognosis of patients with myeloma receiving high-dose therapy and auto-transplants
    • Tricot G, Sawyer JR, Jagannath S, et al. Unique role of cytogenetics in the prognosis of patients with myeloma receiving high-dose therapy and auto-transplants. J Clin Oncol 1997; 15:2659-2666.
    • (1997) J Clin Oncol , vol.15 , pp. 2659-2666
    • Tricot, G.1    Sawyer, J.R.2    Jagannath, S.3
  • 43
    • 0028880424 scopus 로고
    • Poor prognosis in multiple myeloma is associated only with partial or complete deletions of chromosome 13 or abnormalities involving 11q and not with other karyotype abnormalities
    • Tricot G, Barlogie B, Jagannath S, et al. Poor prognosis in multiple myeloma is associated only with partial or complete deletions of chromosome 13 or abnormalities involving 11q and not with other karyotype abnormalities. Blood 1995; 86:4250-4256.
    • (1995) Blood , vol.86 , pp. 4250-4256
    • Tricot, G.1    Barlogie, B.2    Jagannath, S.3
  • 44
    • 7144255524 scopus 로고    scopus 로고
    • Prognostic value of cytogenetics in multiple myeloma
    • Seong C, Delasalle K, Hayes K, et al. Prognostic value of cytogenetics in multiple myeloma. Br J Haematol 1998; 101:189-194.
    • (1998) Br J Haematol , vol.101 , pp. 189-194
    • Seong, C.1    Delasalle, K.2    Hayes, K.3
  • 45
    • 20244363331 scopus 로고    scopus 로고
    • Chromosome abnormalities clustering and its implications fbr pathogenesis and prognosis in myeloma
    • Debes-Marun CS, Dewald GW, Bryant S, et al. Chromosome abnormalities clustering and its implications fbr pathogenesis and prognosis in myeloma. Leukemia 2003; 17:427-436.
    • (2003) Leukemia , vol.17 , pp. 427-436
    • Debes-Marun, C.S.1    Dewald, G.W.2    Bryant, S.3
  • 46
    • 0035496928 scopus 로고    scopus 로고
    • Hypodiploidy is a major prognostic factor in multiple myeloma
    • Smadja NV, Bastard C, Brigaudeau C, et al. Hypodiploidy is a major prognostic factor in multiple myeloma. Blood 2001; 98:2229-2238.
    • (2001) Blood , vol.98 , pp. 2229-2238
    • Smadja, N.V.1    Bastard, C.2    Brigaudeau, C.3
  • 47
    • 18544363372 scopus 로고    scopus 로고
    • Both hypodiploidy and deletion of chromosome 13 independently confer poor prognosis in multiple myeloma
    • Fassas AB, Spencer T, Sawyer J, et al. Both hypodiploidy and deletion of chromosome 13 independently confer poor prognosis in multiple myeloma. Br J Haematol 2002; 118:1041-1047.
    • (2002) Br J Haematol , vol.118 , pp. 1041-1047
    • Fassas, A.B.1    Spencer, T.2    Sawyer, J.3
  • 48
    • 0038495926 scopus 로고    scopus 로고
    • Continuous absence of metaphase-defined cytogenetic abnormalities, especially of chromosome 13 and hypodiploidy, ensures long-term survival in multiple myeloma treated with Total Therapy I: Interpretation in the context of global gene expression
    • Shaughnessy J, Jacobson J, Sawyer J, et al. Continuous absence of metaphase-defined cytogenetic abnormalities, especially of chromosome 13 and hypodiploidy, ensures long-term survival in multiple myeloma treated with Total Therapy I: interpretation in the context of global gene expression. Blood 2003; 101:3849-3856.
    • (2003) Blood , vol.101 , pp. 3849-3856
    • Shaughnessy, J.1    Jacobson, J.2    Sawyer, J.3
  • 49
    • 27744568383 scopus 로고    scopus 로고
    • Relationship of patient survival and chromosome anomalies detected in metaphase and/or interphase cells at diagnosis of myeloma
    • [Epub ahead of print]
    • Dewald G, Therneau T, Larson D, et al. Relationship of patient survival and chromosome anomalies detected in metaphase and/or interphase cells at diagnosis of myeloma. Blood 2005 [Epub ahead of print].
    • (2005) Blood
    • Dewald, G.1    Therneau, T.2    Larson, D.3
  • 50
    • 1842557964 scopus 로고    scopus 로고
    • The t(4; 14) is associated with poor prognosis in myeloma patients undergoing autologous stem cell transplant
    • Chang H, Sloan S, Li D, et al. The t(4; 14) is associated with poor prognosis in myeloma patients undergoing autologous stem cell transplant. Br J Haematol 2004; 125:64-68.
    • (2004) Br J Haematol , vol.125 , pp. 64-68
    • Chang, H.1    Sloan, S.2    Li, D.3
  • 51
    • 0038142356 scopus 로고    scopus 로고
    • Clinical and biologic implications of recurrent genomic aberrations in myeloma
    • Fonseca R, Blood E, Rue M, et al. Clinical and biologic implications of recurrent genomic aberrations in myeloma. Blood 2003; 101:4569-4575.
    • (2003) Blood , vol.101 , pp. 4569-4575
    • Fonseca, R.1    Blood, E.2    Rue, M.3
  • 52
    • 0037441747 scopus 로고    scopus 로고
    • In multiple myeloma, t(4; 14) (p 16; q32) is an adverse prognostic factor irrespective of FGFR3 expression
    • Keats JJ, Reiman T. Maxwell CA, et al. In multiple myeloma, t(4; 14) (p 16; q32) is an adverse prognostic factor irrespective of FGFR3 expression. Blood 2003; 101:1520-1529.
    • (2003) Blood , vol.101 , pp. 1520-1529
    • Keats, J.J.1    Reiman, T.2    Maxwell, C.A.3
  • 53
    • 85030598889 scopus 로고    scopus 로고
    • Clinical implications of t(11; 14)(q13; q32), t(4; 14)(p16.3; q32), and -17p13 in myeloma patients treated with high-dose therapy
    • (Abstract #334)
    • Gertz MA, Lacy MQ, Dispenzieri A, et al. Clinical implications of t(11; 14)(q13; q32), t(4; 14)(p16.3; q32), and -17p13 in myeloma patients treated with high-dose therapy. Blood 2005; 103(suppl):99a (Abstract #334).
    • (2005) Blood , vol.103 , Issue.SUPPL.
    • Gertz, M.A.1    Lacy, M.Q.2    Dispenzieri, A.3
  • 54
    • 11144219996 scopus 로고    scopus 로고
    • p53 gene deletion detected by fluorescence in situ hybridization is an adverse prognostic factor for patients with multiple myeloma following autologous stem cell transplantation
    • Chang H, Qi C, Yi QL, et al. p53 gene deletion detected by fluorescence in situ hybridization is an adverse prognostic factor for patients with multiple myeloma following autologous stem cell transplantation. Blood 2005; 105:358-360.
    • (2005) Blood , vol.105 , pp. 358-360
    • Chang, H.1    Qi, C.2    Yi, Q.L.3
  • 55
    • 0032147210 scopus 로고    scopus 로고
    • Presence of a p53 gene deletion in patients with multiple myeloma predicts for short survival after conventional-dose chemotherapy
    • Drach J, Ackermann J, Fritz E, et al. Presence of a p53 gene deletion in patients with multiple myeloma predicts for short survival after conventional-dose chemotherapy. Blood 1998; 92:802-809.
    • (1998) Blood , vol.92 , pp. 802-809
    • Drach, J.1    Ackermann, J.2    Fritz, E.3
  • 56
    • 0035883062 scopus 로고    scopus 로고
    • The t(4; 14)(p16.3; q32) is strongly associated with chromosome 13 abnormalities in both multiple myeloma and monoclonal gammopathy of undetermined significance
    • Fonseca R, Oken MM, Greipp, PR. The t(4; 14)(p16.3; q32) is strongly associated with chromosome 13 abnormalities in both multiple myeloma and monoclonal gammopathy of undetermined significance. Blood 2001; 98:1271-1272.
    • (2001) Blood , vol.98 , pp. 1271-1272
    • Fonseca, R.1    Oken, M.M.2    Greipp, P.R.3
  • 57
    • 0037085787 scopus 로고    scopus 로고
    • Oncogenesis of multiple myeloma: 14q32 and 13q chromosomal abnormalities are not randomly distributed, but correlate with natural history, immunological features, and clinical presentation
    • Avet-Loiseau H, Facon T, Grosbois B, et al. Oncogenesis of multiple myeloma: 14q32 and 13q chromosomal abnormalities are not randomly distributed, but correlate with natural history, immunological features, and clinical presentation. Blood 2002; 99:2185-2191.
    • (2002) Blood , vol.99 , pp. 2185-2191
    • Avet-Loiseau, H.1    Facon, T.2    Grosbois, B.3
  • 58
    • 0141481984 scopus 로고    scopus 로고
    • The recurrent IgH translocations are highly associated with nonhyperdiploid variant multiple myeloma
    • Fonseca R, Debes-Marun CS, Picken EB, et al. The recurrent IgH translocations are highly associated with nonhyperdiploid variant multiple myeloma. Blood 2003; 102:2562-2567.
    • (2003) Blood , vol.102 , pp. 2562-2567
    • Fonseca, R.1    Debes-Marun, C.S.2    Picken, E.B.3
  • 59
    • 16844377305 scopus 로고    scopus 로고
    • Elevated expression of CKS1B at 1q21 is highly correlated with short survival in myeloma
    • Presented at the 46th Annual Meeting of the American Society of Hematology, December 4-7, San Diego, CA Abstract #77
    • Zhan F, Sawyer J, Gupta S, et al. Elevated expression of CKS1B at 1q2I is highly correlated with short survival in myeloma. Presented at the 46th Annual Meeting of the American Society of Hematology, December 4-7, 2004; San Diego, CA Abstract #77.
    • (2004)
    • Zhan, F.1    Sawyer, J.2    Gupta, S.3
  • 60
    • 0043245842 scopus 로고    scopus 로고
    • Soluble receptor activator of nuclear factor kappaB ligand-osteoprotegerin ratio predicts survival in multiple myeloma: Proposal for a novel prognostic index
    • Terpos E, Szydlo R, Apperley JF, et al. Soluble receptor activator of nuclear factor kappaB ligand-osteoprotegerin ratio predicts survival in multiple myeloma: proposal for a novel prognostic index. Blood 2003; 102:1064-1069.
    • (2003) Blood , vol.102 , pp. 1064-1069
    • Terpos, E.1    Szydlo, R.2    Apperley, J.F.3
  • 61
    • 0141707692 scopus 로고    scopus 로고
    • Serum levels of macrophage inflammatory protein-1 alpha (MIP-lalpha) correlate with the extent of bone disease and survival in patients with multiple myeloma
    • Terpos E, Politou M, Szydlo R, et al. Serum levels of macrophage inflammatory protein-1 alpha (MIP-lalpha) correlate with the extent of bone disease and survival in patients with multiple myeloma. Br J Haematol 2003; 123:106-109.
    • (2003) Br J Haematol , vol.123 , pp. 106-109
    • Terpos, E.1    Politou, M.2    Szydlo, R.3
  • 62
    • 0035207952 scopus 로고    scopus 로고
    • Increased bone marrow microvessel density in newly diagnosed multiple myeloma carries a poor prognosis
    • Munshi NC, Wilson C. Increased bone marrow microvessel density in newly diagnosed multiple myeloma carries a poor prognosis. Semin Oncol 2001; 28:565-569.
    • (2001) Semin Oncol , vol.28 , pp. 565-569
    • Munshi, N.C.1    Wilson, C.2
  • 63
    • 0032006829 scopus 로고    scopus 로고
    • Elevated serum concentrations of hepatocyte growth factor in patients with multiple myeloma
    • The Nordic Myeloma Study Group
    • Seidel C, Borset M, Turesson I, et al. Elevated serum concentrations of hepatocyte growth factor in patients with multiple myeloma. The Nordic Myeloma Study Group. Blood 1998; 91:806-812.
    • (1998) Blood , vol.91 , pp. 806-812
    • Seidel, C.1    Borset, M.2    Turesson, I.3
  • 64
    • 0037312547 scopus 로고    scopus 로고
    • Low p27Yipl expression is an independent adverse prognostic factor in patients with multiple myeloma
    • Filipits M, Pohl G, Stranzl T, et al. Low p27Yipl expression is an independent adverse prognostic factor in patients with multiple myeloma. Clin Cancer Res 2003; 9:820-826.
    • (2003) Clin Cancer Res , vol.9 , pp. 820-826
    • Filipits, M.1    Pohl, G.2    Stranzl, T.3
  • 65
  • 66
    • 0032929769 scopus 로고    scopus 로고
    • Total therapy with tandem transplants for newly diagnosed multiple myeloma
    • Barlogie B, Jagannath S, Desikan KR, et al. Total therapy with tandem transplants for newly diagnosed multiple myeloma. Blood 1999; 93:55-65.
    • (1999) Blood , vol.93 , pp. 55-65
    • Barlogie, B.1    Jagannath, S.2    Desikan, K.R.3
  • 67
    • 0038509089 scopus 로고    scopus 로고
    • Criteria for the classification of monoclonal gammopathies, multiple myeloma and related disorders: A report of the International Myeloma Working Group
    • The International Myeloma Working Group
    • The International Myeloma Working Group. Criteria for the classification of monoclonal gammopathies, multiple myeloma and related disorders: a report of the International Myeloma Working Group. Br J Haematol 2003; 121:749-757.
    • (2003) Br J Haematol , vol.121 , pp. 749-757
  • 68
    • 0027523010 scopus 로고
    • Initial versus deferred melphalan-prednisone therapy for asymptomatic multiple myeloma stage I - A randomized study
    • Myeloma Group of Western Sweden
    • Hjorth M, Hellquist L, Holmberg E, et al. Initial versus deferred melphalan-prednisone therapy for asymptomatic multiple myeloma stage I--a randomized study. Myeloma Group of Western Sweden. EurJ Haematol 1993; 50:95-102.
    • (1993) EurJ Haematol , vol.50 , pp. 95-102
    • Hjorth, M.1    Hellquist, L.2    Holmberg, E.3
  • 69
    • 17944376919 scopus 로고    scopus 로고
    • Thalidomide for previously untreated indolent or smoldering multiple myeloma
    • Rajkumar SV, Dispenzieri A, Fonseca F, et al. Thalidomide for previously untreated indolent or smoldering multiple myeloma. Leukemia 2001; 15:1274-1276.
    • (2001) Leukemia , vol.15 , pp. 1274-1276
    • Rajkumar, S.V.1    Dispenzieri, A.2    Fonseca, F.3
  • 70
    • 0034102430 scopus 로고    scopus 로고
    • Long-term survival of stage I multiple myeloma given chemotherapy just after diagnosis or at progression of the disease: A multicentre randomized study
    • Cooperative Group of Study and Treatment of Multiple Myeloma
    • Riccardi A, Mora O, Tinelli C, et al. Long-term survival of stage I multiple myeloma given chemotherapy just after diagnosis or at progression of the disease: a multicentre randomized study. Cooperative Group of Study and Treatment of Multiple Myeloma. Br J Cancer 2000; 82:1254-1260.
    • (2000) Br J Cancer , vol.82 , pp. 1254-1260
    • Riccardi, A.1    Mora, O.2    Tinelli, C.3
  • 71
    • 8944220233 scopus 로고    scopus 로고
    • A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma
    • Intergroupe Francais du Myelome
    • Attal M, Harousseau JL, Stoppa AM, et al. A prospective, randomized trial of autologous bone marrow transplantation and chemotherapy in multiple myeloma. Intergroupe Francais du Myelome. N Engl J Med 1996; 335:91-97.
    • (1996) N Engl J Med , vol.335 , pp. 91-97
    • Attal, M.1    Harousseau, J.L.2    Stoppa, A.M.3
  • 72
    • 0037739753 scopus 로고    scopus 로고
    • High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma
    • Child JA, Morgan GJ, Davies FE, et al. High-dose chemotherapy with hematopoietic stem-cell rescue for multiple myeloma. N Engl J Med 2003; 348:1875-1883.
    • (2003) N Engl J Med , vol.348 , pp. 1875-1883
    • Child, J.A.1    Morgan, G.J.2    Davies, F.E.3
  • 73
    • 0034933036 scopus 로고    scopus 로고
    • Interferon as therapy for multiple myeloma: An individual patient data overview of 24 randomized trials and 4012 patients
    • Myeloma Trialists' Collaborative Group
    • Myeloma Trialists' Collaborative Group. Interferon as therapy for multiple myeloma: an individual patient data overview of 24 randomized trials and 4012 patients. Br J Haematol 2001; 113:1020-1034.
    • (2001) Br J Haematol , vol.113 , pp. 1020-1034
  • 74
    • 85030598088 scopus 로고    scopus 로고
    • A prospective randomized trial of oral melphalan, prednisone, thalidomide (MPT) vs oral melphalan, prednisone (MO): An interim analysis
    • Presented at the 46th Annual Meeting of the American Society of Hematology, December 4-7, San Diego, CA. Abstract #207
    • Palumbo A, Bertola A, Musto P, et al. A prospective randomized trial of oral melphalan, prednisone, thalidomide (MPT) vs oral melphalan, prednisone (MO): an interim analysis. Presented at the 46th Annual Meeting of the American Society of Hematology, December 4-7, 2004; San Diego, CA. Abstract #207.
    • (2004)
    • Palumbo, A.1    Bertola, A.2    Musto, P.3
  • 75
    • 21944449652 scopus 로고    scopus 로고
    • Treatment of myeloma in patients not eligible for transplantation
    • Jagannath S. Treatment of myeloma in patients not eligible for transplantation. Curr Treat Options Oncol 2005; 6:241-253.
    • (2005) Curr Treat Options Oncol , vol.6 , pp. 241-253
    • Jagannath, S.1
  • 76
    • 0037208595 scopus 로고    scopus 로고
    • Thalidomide alone or with dexamethasone for previously untreated multiple myeloma
    • Weber D, Rankin K, Gavino M, et al. Thalidomide alone or with dexamethasone for previously untreated multiple myeloma. J Clin Oncol 2003; 21:16-19.
    • (2003) J Clin Oncol , vol.21 , pp. 16-19
    • Weber, D.1    Rankin, K.2    Gavino, M.3
  • 77
    • 0036843032 scopus 로고    scopus 로고
    • Combination therapy with thalidomide plus dexamethasone for newly diagnosed myeloma
    • Rajkumar SV, Hayman S, Gertz MA, et al. Combination therapy with thalidomide plus dexamethasone for newly diagnosed myeloma. J Clin Oncol 2002; 20:4319-4323.
    • (2002) J Clin Oncol , vol.20 , pp. 4319-4323
    • Rajkumar, S.V.1    Hayman, S.2    Gertz, M.A.3
  • 78
    • 22044452126 scopus 로고    scopus 로고
    • Superiority of thalidomide and dexamethasone over vincristine-doxorubicin dexamethasone (VAD) as primary therapy in preparation for autologous transplantation for multiple myeloma
    • Cavo M, Zamagni E, Tosi P, et al. Superiority of thalidomide and dexamethasone over vincristine-doxorubicin dexamethasone (VAD) as primary therapy in preparation for autologous transplantation for multiple myeloma. Blood 2005; 106:35-39.
    • (2005) Blood , vol.106 , pp. 35-39
    • Cavo, M.1    Zamagni, E.2    Tosi, P.3
  • 79
    • 21344450660 scopus 로고    scopus 로고
    • Combination therapy with CC-5013 (lenalidomide; Revfimid™) plus dexamethasone (REV/DEX) for newly diagnosed myeloma
    • (Abstract #331)
    • Rajkumar SV, Hayman SR, Lacy MQ, et al. Combination therapy with CC-5013 (lenalidomide; Revfimid™) plus dexamethasone (REV/DEX) for newly diagnosed myeloma. Blood 2005; 104(suppl):98a (Abstract #331).
    • (2005) Blood , vol.104 , Issue.SUPPL.
    • Rajkumar, S.V.1    Hayman, S.R.2    Lacy, M.Q.3
  • 80
    • 0032211193 scopus 로고    scopus 로고
    • High-dose therapy and autologous peripheral blood stem cell transplantation in multiple myeloma: Up-front or rescue treatment? Results of a multicenter sequential randomized clinical trial
    • Fermand JP, Ravaud P, Chevret S, et al. High-dose therapy and autologous peripheral blood stem cell transplantation in multiple myeloma: up-front or rescue treatment? Results of a multicenter sequential randomized clinical trial. Blood 1998; 92:3131-3136.
    • (1998) Blood , vol.92 , pp. 3131-3136
    • Fermand, J.P.1    Ravaud, P.2    Chevret, S.3
  • 81
    • 0034791513 scopus 로고    scopus 로고
    • Autologous stem cell transplantation in elderly multiple myeloma patients over the age of 70 years
    • Badros A, Barlogie B, Siegel E, et al. Autologous stem cell transplantation in elderly multiple myeloma patients over the age of 70 years. Br J Haematol 2001; 114:600-607.
    • (2001) Br J Haematol , vol.114 , pp. 600-607
    • Badros, A.1    Barlogie, B.2    Siegel, E.3
  • 82
  • 83
    • 15944378835 scopus 로고    scopus 로고
    • CHIR-258, a novel, multitargeted tyrosine kinase inhibitor for the potential treatment of t(4; 14) multiple myeloma
    • Trudel S, Li ZH, Wei E, et al. CHIR-258, a novel, multitargeted tyrosine kinase inhibitor for the potential treatment of t(4; 14) multiple myeloma. Blood 2005; 105:2941-2948.
    • (2005) Blood , vol.105 , pp. 2941-2948
    • Trudel, S.1    Li, Z.H.2    Wei, E.3
  • 84
    • 2542448169 scopus 로고    scopus 로고
    • The occurrence of graft-versus-host disease is the major predictive factor for response to donor lymphocyte infusions in multiple myeloma
    • Lokhorst HM, Wu K, Verdonck LF, et al. The occurrence of graft-versus-host disease is the major predictive factor for response to donor lymphocyte infusions in multiple myeloma. Blood 2004; 103:4362-4364.
    • (2004) Blood , vol.103 , pp. 4362-4364
    • Lokhorst, H.M.1    Wu, K.2    Verdonck, L.F.3
  • 85
    • 0030043438 scopus 로고    scopus 로고
    • Graft-versus-myeloma effect: Proof of principle
    • Tricot G, Vesole DH, Jagannath S, et al. Graft-versus-myeloma effect: proof of principle. Blood 1996; 87:1196-1198.
    • (1996) Blood , vol.87 , pp. 1196-1198
    • Tricot, G.1    Vesole, D.H.2    Jagannath, S.3
  • 86
    • 0032895599 scopus 로고    scopus 로고
    • Molecular and clinical remissions in multiple myeloma: Role of autologous and allogeneic transplantation of hematopoietic cells
    • Corradini P, Voena C, Tarella. C, et al. Molecular and clinical remissions in multiple myeloma: role of autologous and allogeneic transplantation of hematopoietic cells. J Clin Oncol 1999; 17-.208-215.
    • (1999) J Clin Oncol , vol.17 , pp. 208-215
    • Corradini, P.1    Voena, C.2    Tarella, C.3
  • 87
    • 4644249497 scopus 로고    scopus 로고
    • Relapse to prior autograft and chronic graft-versus-host disease are the strongest prognostic factors for outcome of melphatan/fludarabine-based dose-reduced allogencic stem cell transplantation in patients with multiple myeloma
    • Kroger N, Perez-Simon JA, Myint H, et al. Relapse to prior autograft and chronic graft-versus-host disease are the strongest prognostic factors for outcome of melphatan/fludarabine-based dose-reduced allogencic stem cell transplantation in patients with multiple myeloma. Biol Blood Marrow Transplant 2004; 10-.698-708.
    • (2004) Biol Blood Marrow Transplant , vol.10 , pp. 698-708
    • Kroger, N.1    Perez-Simon, J.A.2    Myint, H.3
  • 88
    • 21144446701 scopus 로고    scopus 로고
    • Outcomes for reduced-intensity allogeneic transplantation fbr multiple myeloma: An analysis of prognostic factors from the Chronic Leukaemia Working Party of the EBMT
    • Crawley C, Lalancette M, Szydlo R, et al. Outcomes for reduced-intensity allogeneic transplantation fbr multiple myeloma: an analysis of prognostic factors from the Chronic Leukaemia Working Party of the EBMT. Blood 2005; 105:4532-4539.
    • (2005) Blood , vol.105 , pp. 4532-4539
    • Crawley, C.1    Lalancette, M.2    Szydlo, R.3
  • 89
    • 0036682491 scopus 로고    scopus 로고
    • Autologous stem cell transplantation followed by a dose-reduced allograft induces high complete remission rate in multiple myeloma
    • Kroger N, Schwerdtfeger R, Kiehl M, et al. Autologous stem cell transplantation followed by a dose-reduced allograft induces high complete remission rate in multiple myeloma. Blood 2002; 100:755-760.
    • (2002) Blood , vol.100 , pp. 755-760
    • Kroger, N.1    Schwerdtfeger, R.2    Kiehl, M.3
  • 90
    • 0142152420 scopus 로고    scopus 로고
    • Allografting with nomnyeloablative conditioning following cytoreductive autografts for the treatment of patients with multiple myeloma
    • Maloney DG, Molina AJ, Sahebi F, et al. Allografting with nomnyeloablative conditioning following cytoreductive autografts for the treatment of patients with multiple myeloma. Blood 2003; 102:3447-3454.
    • (2003) Blood , vol.102 , pp. 3447-3454
    • Maloney, D.G.1    Molina, A.J.2    Sahebi, F.3
  • 92
    • 0037973279 scopus 로고    scopus 로고
    • A phase 2 study of bortezomib in relapsed, refractory myeloma
    • Richardson PG, Barlogie B, Berenson J, et al. A phase 2 study of bortezomib in relapsed, reftactory myeloma. N Engl J Med 2003; 348:2609-2617.
    • (2003) N Engl J Med , vol.348 , pp. 2609-2617
    • Richardson, P.G.1    Barlogie, B.2    Berenson, J.3
  • 93
    • 0036839013 scopus 로고    scopus 로고
    • Immunomodulatory drug CC-5013 overcomes drug resistance and is well tolerated in patients with relapsed multiple myeloma
    • Richardson PG, Schlossman RL, Weller E, et al. Immunomodulatory drug CC-5013 overcomes drug resistance and is well tolerated in patients with relapsed multiple myeloma. Blood 2002; 100:3063-3067.
    • (2002) Blood , vol.100 , pp. 3063-3067
    • Richardson, P.G.1    Schlossman, R.L.2    Weller, E.3
  • 94
    • 30944436753 scopus 로고    scopus 로고
    • Bortezomib appears to overcome poor prognosis conferred by chromosome 13 deletion in phase 2 and 3 trials
    • Late-breaking abstracts from the 41st Annual Meeting of. the American Society of Clinical Oncology. (Abstract #6501)
    • Jagannath S, Richardson PG, Sonneveld P, et al. Bortezomib appears to overcome poor prognosis conferred by chromosome 13 deletion in phase 2 and 3 trials. Late-breaking abstracts from the 41st Annual Meeting of the American Society of Clinical Oncology. J Clin Oncol 2005; 23(16 suppl): 560s (Abstract #6501).
    • (2005) J Clin Oncol , vol.23 , Issue.16 SUPPL.
    • Jagannath, S.1    Richardson, P.G.2    Sonneveld, P.3


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