Hepatic pharmacokinetics of propranolol in rats with adjuvant-induced systemic inflammation

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 290, Issue 2, 2006, Pages

  Hung, Daniel Y ^a   Siebert, Gerhard A ^a   Chang, Ping ^a   Whitehouse, Michael W ^a   Fletcher, Linda ^b   Crawford, Darrell H G ^b   Roberts, Michael S ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b PRINCESS ALEXANDRA HOSPITAL   (Australia)

Author keywords

Acidic vesicles; Ion trapping; Iron overload

Indexed keywords

ADJUVANT; CYTOCHROME P450; IRON; OROSOMUCOID; PROPRANOLOL; ALANINE AMINOTRANSFERASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASE; BETA ADRENERGIC RECEPTOR BLOCKING AGENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DILUTION; DRUG DISPOSITION; ENZYME ACTIVITY; FEMALE; INFLAMMATION; IRON OVERLOAD; IRON STORAGE; LIVER CELL; LIVER LYSOSOME; LIVER METABOLISM; LIVER MITOCHONDRION; LIVER STRUCTURE; NONHUMAN; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RAT; TRANSMISSION ELECTRON MICROSCOPY; ALGORITHM; ANIMAL; ARTHRITIS; BLOOD; CHEMICALLY INDUCED DISORDER; CYTOSKELETON; DRUG EFFECT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; LIVER; METABOLISM; ORGAN SIZE; OXYGEN CONSUMPTION; PATHOLOGY; PERFUSION; STATISTICAL ANALYSIS;

ADRENERGIC BETA-ANTAGONISTS; ALANINE TRANSAMINASE; ALGORITHMS; ALKALINE PHOSPHATASE; ANIMALS; ARTHRITIS, EXPERIMENTAL; ASPARTATE AMINOTRANSFERASES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYTOCHROME P-450 ENZYME SYSTEM; CYTOSKELETON; DATA INTERPRETATION, STATISTICAL; FEMALE; HEPATOCYTES; INFLAMMATION; IRON; LIVER; ORGAN SIZE; OROSOMUCOID; OXYGEN CONSUMPTION; PERFUSION; PROPRANOLOL; RATS;

EID: 33644866367     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.00155.2005     Document Type: Article

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