Chronic hypoxia accelerates the progression of atherosclerosis in apolipoprotein E-knockout mice

Hypertension Research

Volumn 28, Issue 10, 2005, Pages 837-845

  Nakano, Daisuke ^a   Hayashi, Tetsuya ^a   Tazawa, Naoko ^a   Yamashita, Chika ^a   Inamoto, Sakiko ^a   Okuda, Nobuaki ^a   Mori, Tatsuhiko ^a   Sohmiya, Koichi ^a   Kitaura, Yasushi ^a   Okada, Yoshikatsu ^a   Matsumura, Yasuo ^a  

^a OSAKA MEDICAL COLLEGE   (Japan)

Author keywords

Apolipoprotein E; Atherosclerosis; Hypoxia; Matrix metalloproteinase; Superoxide

Indexed keywords

APOLIPOPROTEIN E; CYCLINE; GELATINASE B; LOW DENSITY LIPOPROTEIN CHOLESTEROL; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; SUPEROXIDE; CHOLESTEROL; LOW DENSITY LIPOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; CELL PROLIFERATION; CONTROLLED STUDY; DISEASE COURSE; FEMALE; HYPOXIA; MALE; MOUSE; NONHUMAN; SEX DIFFERENCE; SMOOTH MUSCLE FIBER; ANIMAL; ANOXIA; BLOOD; CHRONIC DISEASE; METABOLISM; MOUSE MUTANT; PATHOLOGY; PHYSIOLOGY;

ANIMALS; ANOXIA; APOLIPOPROTEINS E; ATHEROSCLEROSIS; CHOLESTEROL; CHRONIC DISEASE; FEMALE; LIPOPROTEINS, LDL; MALE; MATRIX METALLOPROTEINASE 9; MICE; MICE, KNOCKOUT; REACTIVE OXYGEN SPECIES; SUPEROXIDES;

EID: 33644852310     PISSN: 09169636     EISSN: 13484214     Source Type: Journal    
DOI: 10.1291/hypres.28.837     Document Type: Article

References (39)

1. Parthasarathy S, Young SG, Witztum JL, Pittman RC, Steinberg D: Probucol inhibits oxidative modification of low-density lipoprotein. J Clin Invest 1986; 77: 641-644.
2. phox is required for atherosclerotic lesion progression in ApoE-/- mice. J Clin Invest 2001; 108: 1513-1522.
3. Williams RJ, Motteram JM, Sharp CH, Gallagher PJ: Dietary vitamin E and the attenuation of early lesion development in modified Watanabe rabbits. Atherosclerosis 1992; 94: 153-159.
4. Rajagopalan S, Meng XP, Ramasamy S, Harrison DG, Galis ZS: Reactive oxygen species produced by macrophage-derived foam cells regulate the activity of vascular matrix metalloproteinases in vitro. J Clin Invest 1996; 98: 2572-2579.
5. Yasunari K, Maeda K, Nakamura M, Yoshikawa J: Carvedilol inhibits pressure-induced increase in oxidative stress in coronary smooth muscle cells. Hypertens Res 2002; 25: 419-425.
6. Pagano PJ, Clark JK, Cifuentes-Pagano ME, Clark SM, Callis GM, Quinn MT: Localization of a constitutively active, phagocyte-like NADPH oxidase in rabbit aortic adventitia: enhanced by angiotensin II. Proc Natl Acad Sci U S A 1997; 94: 14483-14488.
7. Yin CJ, Xu JW, Takahashi K, Nara Y, Yamori Y: Tea polyphenols regulate nicotinamide adenine dinucleotide phosphate oxidase subunit expression and ameliorate angiotensin II-induced hyperpermeability in endothelial cells. Hypertens Res 2003; 26: 823-828.
8. Pinsky DJ, Oz MC, Koga S, et al: Cardiac preservation is enhanced in a heterotopic rat transplant model by supplementing the nitric oxide pathway. J Clin Invest 1994; 93: 2291-2297.
9. Griendling KK, Ushio-Fukai M: Redox control of vascular smooth muscle proliferation. J Lab Clin Med 1998; 132: 9-15.
10. G-nitro-L-arginine methyl ester-induced hypertension: modulation of proinflammatory signals. Hypertension 2000; 36: 103-109.
11. Galis ZS, Sukhova GK, Lark MW, Libby P: Increased expression of matrix metalloproteinases and matrix degrading activity in vulnerable regions of human atherosclerotic plaques. J Clin Invest 1994; 94: 2493-2503.
12. Damås JK, Wæhre T, Yndestad A, Gullestad L, Aukrust P: Atherosclerotic plaque stabilization - potential role for immunomodulatory therapy. Vasc Dis Prevent 2004; 1: 17-31.
13. Duranteau J, Chandel NS, Kulisz A, Shao Z, Schumacker PT: Intracellular signaling by reactive oxygen species during hypoxia in cardiomyocytes. J Biol Chem 1998; 273: 11619-11624.
14. Aoki M, Nata T, Morishita R, et al: Endothelial apoptosis induced by oxidative stress through activation of NF-κB. Antiapoptotic effect of antioxidant agents on endothelial cells. Hypertension 2001; 38: 48-55.
15. Chen L, Einbinder E, Zhang Q, Hasday J, Balke WC, Scharf SM: Oxidative stress and left ventricular function with chronic intermittent hypoxia in rats. Am J Respir Crit Care Med 2005; 172: 915-920.
16. Martin JM, Carrizo SJ, Vicente E, Agusti AGN: Long-term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational study. Lancet 2005; 365: 1046-1053.
17. Takai S, Jin D, Sakaguchi M, et al: Comparative effects of candesartan and amlodipine in a monkey atherosclerotic model. Hypertens Res 2004; 27: 517-522.
18. Okuda N, Hayashi T, Mori T, et al: Nifedipine enhances the cardioprotective effect of an angiotensin-II receptor blocker in an experimental animal model of heart failure. Hypertens Res 2005; 28: 431-438.
19. Isoda K, Shiigai M, Ishigai N, et al: Deficiency of interleukin-1 receptor antagonist promotes neointimal formation after injury. Circulation 2003; 108: 516-518.
20. Miller FJ, Cutterman DD, Rios DC, Heistad DD, Davidson BL: Superoxide production in vascular smooth muscle contributes to oxidative stress and impaired relaxation in atherosclerosis. Circ Res 1998; 82: 1298-1305.
21. Nakano D, Itoh C, Ishii F, et al: Effects of sesamin on aortic oxidative stress and endothelial dysfunction in deoxycorticosterone acetate-salt hypertensive rats. Biol Pharm Bull 2003; 26: 1701-1705.
22. Li Y, Zhu H, Kuppusamy P, Rouband V, Zweier JL, Trush MA: Validation of lucigenin (bis-N-methylacridinium) as a chemilumigenic probe for detecting superoxide anion radical production by enzymatic and cellular systems. J Biol Chem 1998; 273: 2015-2023.
23. Skatchkov MP, Sperling D, Hink U, et al: Validation of lucigenin as a chemiluminescent probe to monitor vascular superoxide as well as basal vascular nitric oxide production. Biochem Biophys Res Commun 1999; 254: 319-324.
24. Hayashi T, Sohmiya K, Ukimura A, et al: Angiotensin II receptor blockade prevents microangiopathy and preserves diastolic function in the diabetic rat heart. Heart 2003; 89: 1236-1242.
25. Hayashi T, Nozawa M, Sohmiya K, et al: Efficacy of pancreatic transplantation on cardiovascular alterations in diabetic rats: an ultrastructural and immunohistochemical study. Transplant Proc 1998; 30: 335-338.
26. Budhiraja R, Tuder RM, Hassoun PM: Endothelial dysfunction in pulmonary hypertension. Circulation 2004; 109: 159-165.
27. Carmena R, Duriez P, Fruchart JC: Atherogenic lipoprotein particles in atherosclerosis. Circulation 2004; 109 (Suppl III): III-2-III-7.
28. Matsumoto K, Taniguchi T, Fujioka Y, Shimizu H, Ishikawa Y, Yokoyama M: Effects of hypoxia on cholesterol metabolism in human monocyte-derived macrophages. Life Sci 2000; 67: 2083-2091.
29. Wada Y, Sugiyama A, Yamamoto T, et al: Lipid accumulation in smooth muscle cells under LDL loading is independent of LDL receptor pathway and enhanced by hypoxic conditions. Arterioscler Thromb Vasc Biol 2002; 22: 1712-1719.
30. Sato H, Sato M, Kanai H, et al: Mitochondrial reactive oxygen species and c-Src play a critical role in hypoxic response in vascular smooth muscle cells. Cardiovasc Res 2005; 67: 714-722.
31. Schäfer M, Schäfer C, Ewald N, Piper HM, Noll TH: Role of redox signaling in the autonomous proliferative response of endothelial cells to hypoxia. Circ Res 2003; 92: 1010-1015.
32. Cathcart MK: Regulation of superoxide anion production by NADPH oxidase in monocytes/macrophages: contributions to atherosclerosis. Arterioscler Thromb Vasc Biol 2004; 24: 23-28.
33. Kalinina N, Agrotis A, Tararak E, et al: Cytochrome b558-dependent NAD(P)H oxidase-phox units in smooth muscle and macrophages of atherosclerotic lesions. Arterioscler Thromb Vasc Biol 2002; 22: 2037-2043.
34. Galis ZS, Khatri JJ: Matrix metalloproteinases in vascular remodeling and atherogenesis. The good, the bad, and the ugly. Circ Res 2002; 90: 251-262.
35. Galia ZS, Sukhova GK, Kranzhöfer R, Clark S, Libby P: Macrophage foam cells from experimental atheroma constitutively produce matrix-degrading proteinases. Proc Natl Acad Sci U S A 1995; 92: 402-406.
36. Brown DL, Hibbs MS, Kearney M, Loushin C, Isner JM: Identification of 92-kD gelatinase in human coronary atherosclerotic lesions. Association of active enzyme synthesis with unstable angina. Circulation 1995; 91: 2125-2131.
37. Lemaître V, O'Byrne TK, Borczuk AC, Okada Y, Tall AR, D'Armiento J: ApoE knockout mice expressing human matrix metalloproteinase-1 in macrophages have less advanced atherosclerosis. J Clin Invest 2001; 107: 1227-1234.
38. Potier M, Elliot SJ, Tack I, et al: Expression and regulation of estrogen receptors in mesangial cells: influence on matrix metalloproteinase-9. J Am Soc Nephrol 2001; 12: 241-251.
39. Xu Y, Arenas IA, Armstrong SJ, Davidge ST: Estrogen modulation of left ventricular remodeling in the aged heart. Cardiovasc Res 2003; 57: 388-394.