Roles for Gcn5p and Ada2p in transcription and nucleotide excision repair at the Saccharomyces cerevisiae MET16 gene

Nucleic Acids Research

Volumn 34, Issue 3, 2006, Pages 976-985

  Ferreiro, J A ^c   Powell, N G ^a   Karabetsou, N ^b   Mellor, J ^b   Waters, R ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF OVIEDO   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

3' PHOSPHO 5' ADENYLYLSULFATE REDUCTASE; ADAPTOR PROTEIN; CYCLOBUTANE; DIMER; FUNGAL DNA; HISTONE ACETYLTRANSFERASE GCN5; PYRIMIDINE; SACCHAROMYCES CEREVISIAE PROTEIN; UNCLASSIFIED DRUG; ADA2 PROTEIN, S CEREVISIAE; GCN5 PROTEIN, S CEREVISIAE; HISTONE ACETYLTRANSFERASE; MET16 PROTEIN, S CEREVISIAE; OXIDOREDUCTASE; TRANSCRIPTION FACTOR;

ARTICLE; CHROMATIN ASSEMBLY AND DISASSEMBLY; CHROMATIN STRUCTURE; CONTROLLED STUDY; DNA STRAND; EXCISION REPAIR; FUNGUS GROWTH; GENE DELETION; GENE LOCUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; SACCHAROMYCES CEREVISIAE; SENSITIVITY ANALYSIS; STRAIN DIFFERENCE; TRANSCRIPTION INITIATION; TRANSCRIPTION REGULATION; ULTRAVIOLET RADIATION; BIOSYNTHESIS; CHEMISTRY; CHROMATIN; DNA REPAIR; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; PHYSIOLOGY; RADIATION EXPOSURE;

FUNGI; SACCHAROMYCES CEREVISIAE;

CHROMATIN; DNA REPAIR; GENE DELETION; GENE EXPRESSION REGULATION, FUNGAL; HISTONE ACETYLTRANSFERASES; OXIDOREDUCTASES; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; ULTRAVIOLET RAYS;

EID: 33644851078     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkj501     Document Type: Article

References (38)

1. Wolffe,A. (1998) Chromatin: Structure and Function. Academic Press, San Diego, CA.
2. Workman,J.L. and Kingston,R.E. (1998) Alteration of nucleosome structure as a mechanism of transcriptional regulation. Annu. Rev. Biochem., 67, 545-579.
3. Meijer,M. and Smerdon,M.J. (1999) Accessing DNA damage in chromatin: insights from transcription. Bioessays, 21, 596-603.
4. Meyer,P. (2001) Chromatin remodelling. Curr. Opin. Plant Biol., 4, 457-462.
5. Svejstrup,J.Q. (2002) Mechanisms of transcription-coupled DNA repair. Nature Rev. Mol. Cell Biol., 3, 21-29.
6. Li,S. and Smerdon,M.J. (2002) Rpb4 and Rpb9 mediate subpathways of transcription-coupled DNA repair in Saccharomyces cerevisiae. EMBO J., 21, 5921-5929.
7. Powell,N.G., Ferreiro,J., Karabetsou,N., Mellor,J. and Waters,R. (2003) Transcription, nucleosome positioning and protein binding modulate nucleotide excision repair of the Saccharomyces cerevisiae MET17 promoter. DNA repair, 2, 375-386.
8. Wellinger,R.E. and Thoma,F. (1997) Nucleosome structure and positioning modulate nucleotide excision repair in the non-transcribed strand of an active gene. EMBO J., 16, 5046-5056.
9. Tijsterman,M., De Pril,R., Tasseron-de Jong,J.G. and Brouwer,J. (1999) RNA polymerase II transcription suppresses nucleosomal modulation of UV-induced (6-4) photoproduct and cyclobutane pyrimidine dimer repair in yeast. Mol. Cell. Biol., 19, 934-940.
10. Hara,R., Mo,J. and Sancar,A. (2000) DNA damage in the nucleosome core is refractory to repair by human excision nuclease. Mol. Cell. Biol., 20, 9173-9181.
11. Ura,K., Araki,M., Saeki,H., Masutani,C., Ito,T., Iwai,S., Mizukoshi,T., Kaneda,Y. and Hanaoka,F. (2001) ATP-dependent chromatin remodeling facilitates nucleotide excision repair of UV-induced DNA lesions in synthetic dinucleosomes. EMBO J., 20, 2004-2014.
12. Grunstein,M. (1990) Histone function in transcription. Annu. Rev. Cell. Biol., 6, 643-678.
13. Wu,J. and Grunstein,M. (2000) 25 years after the nucleosome model: chromatin modifications. Trends Biochem. Sci., 25, 619-623.
14. Hara,R. and Sancar,A. (2002) The Swi/Snf chromatin-remodeling factor stimulates repair by human excision nuclease in the mononucleosome core particle. Mol. Cell. Biol., 22, 6779-6787.
15. Hara,R. and Sancar,A. (2003) Effect of damage type on stimulation of human excision nuclease by Swi/Snf chromatin remodeling factor. Mol. Cell. Biol., 23, 4121-4125.
16. Teng,Y., Yu,Y. and Waters,R. (2002) The Saccharomyces cerevisiae histone acetyltransferase Gcn5 has a role in the photoreactivation and nucleotide excision repair of UV-induced cyclobutane pyrimidine dimers in the MFA2 gene. J. Mol. Biol., 316, 489-499.
17. Ferreiro,J.A., Powell,N.G., Karabetsou,N., Kent,N.A., Mellor, J. and Waters,R. (2004) Cbf1p modulates chromatin structure, transcription and repair at the Saccharomyces cerevisiae MET16 locus. Nucleic Acids Res., 32, 1617-1626.
18. Sterner,D.E. and Berger,S.L. (2000) Acetylation of histories and transcription-related factors. Microbiol. Mol. Biol. Rev., 64, 435-459.
19. Georgakopoulos,T. and Thireos,G. (1992) Two distinct yeast transcriptional activators require the function of the GCN5 protein to promote normal levels of transcription. EMBO J., 11, 4145-4152.
20. Grant,P.A., Duggan,L., Cote,J., Roberts,S.M., Brownell,J.E., Candau,R., Ohba,R., Owen-Hughes,T., Allis,C,D., Winston,F., Berger,S.L. and Workman,J.L. (1997) Yeast Gcn5 functions in two multisubunit complexes to acetylate nucleosomal histories: Characterization of an Ada complex and the SAGA (Spt/Ada) complex. Genes Dev., 11, 1640-1650.
21. Pray-Grant,M.G., Schieltz,D., McMahon,S.J., Wood,J.M., Kennedy,E.L., Cook,R.G., Workman,J.L., Yates,J.R.3rd and Grant,P.A. (2002) The novel SLIK histone acetyltransferase complex functions in the yeast retrograde response pathway. Mol. Cell Biol., 22, 8774-8786.
22. Marcus,G., Silverman,N., Berger,S., Horiuchi,J. and Guarente,L. (1994) Functional similarity and physical association between GCN5 and ADA2-putative transcriptional adaptors. EMBO J., 13, 4807-4815.
23. Candau,R. and Berger,S.L. (1996) Structural and functional analysis of yeast putative adaptors: Evidence for an adaptor complex in vivo. J. Biol. Chem., 271, 5237-5245.
24. Barlev,N.A., Candau,R., Wang,L., Darpino,P., Silverman,N. and Berger,S.L. (1995) Characterization of physical interactions of the putative transcriptional adaptor, ADA2, with acidic activation domains and TATA-binding protein. J. Biol. Chem., 270, 19337-19344.
25. Bhaumik,S.R. and Green,M.R. (2002) Differential requirement of SAGA components for recruitment of TATA-box-binding protein to promoters in vivo. Mol. Cell. Biol., 22, 7365-7371.
26. Thomas,D., Barbey,R. and Surdin-Kerjan,Y. (1990) Gene-enzyme relationship in the sulfate assimilation pathway of Saccharomyces cerevisiae. Study of the 3′-phosphoadenylylsulfate reductase structural gene. J. Biol. Chem., 265, 15518-15524.
27. Wang,Y., Liu,C.L., Storey,J.D., Tibshirani,R.J., Herschlag,D. and Brown,P.O. (2002) Precision and functional specificity in mRNA decay. Proc. Natl Acad. Sci. USA, 99, 5860-5865.
28. Kuras,L., Chérest,H., Surdin-Kerjan,Y. and Thomas,D. (1996) A heteromeric complex containing the centromere binding factor 1 and two basic leucine zipper factors, Met4 and Met28, mediates the transcription activation of yeast sulfur metabolism. EMBO J., 15, 2519-2529.
29. O'Connell,K.F., Surdin-Kerjan,Y. and Baker,R.E. (1995) Role of the Saccharomyces cerevisiae general regulatory factor CP1 in methionine biosynthetic gene transcription. Mol. Cell. Biol., 15, 1879-1888.
30. Reed,S.H., Boiteux,S. and Waters,R. (1996) UV-induced endonuclease III-sensitive sites at the mating type loci in Saccharomyces cerevisiae are repaired by nucleotide excision repair. RAD7 and RAD16 are not required for their removal from HML alpha. Mol. Gen. Genet., 250, 505-514.
31. Teng,Y., Li,S., Waters,R. and Reed,S.H. (1997) Excision repair at the level of the nucleotide in the Saccharomyces cerevisiae MFA2 gene: mapping of where enhanced repair in the transcribed strand begins or ends and identification of only a partial rad16 requisite for repairing upstream control sequences. J. Mol. Biol., 267, 324-337.
32. Kent,N.A. and Mellor,J. (1995) Chromatin structure snap-shots: Rapid nuclease digestion of chromatin in yeast. Nucleic Acids Res., 23, 3786-3787.
33. Teng,Y. and Waters,R. (2000) Excision repair at the level of the nucleotide in the upstream control region, the coding sequence and in the region where transcription terminates of the Saccharomyces cerevisiae MFA2 gene and the role of RAD26. Nucleic Acids Res., 28, 1114-1119.
34. Topalidou,I. and Thireos,G. (2003) Gcn4 occupancy of open reading frame regions results in the recruitment of chromatin-modifying complexes but not the mediator complex. EMBO Rep., 4, 872-976.
35. Balasubramanian,R., Pray-Grant,M.G., Selleck,W., Grant,P.A. and Tan,S. (2002) Role of the Ada2 and Ada.3 transcriptional coactivators in histone acetylation. J. Biol. Chem., 277, 7989-7995.
36. Berger,S.L., Pina,B., Silverman,N., Marcus,G.A., Agapite,J., Regier,J.L., Triezenberg,S.J. and Guarente,L. (1992) Genetic isolation of ADA2: A potential transcriptional adaptor required for function of certain acidic activation domains. Cell, 70, 251-265.
37. Zheng,Y., Pao,A., Adair,G.M. and Tang,M. (2001) Cyclobutane pyrimidine dimers and bulky chemical DNA adducts are efficiently repaired in both strands of either a transcriptionally active or promoter-deleted APRT gene. J. Biol. Chem., 276, 16786-16796.
38. Yu,Y., Teng,Y., Liu,H., Reed,S.H. and Waters,R. (2005) UV irradiation stimulates histone acetylation and chromatin remodeling at a repressed yeast locus. Proc. Natl Acad. Sci. USA, 102, 8650-8655.