Gene transfer with inducible nitric oxide synthase decreases production of urea by arginase in pulmonary arterial endothelial cells

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 290, Issue 2, 2006, Pages

  Stanley, Kate P ^a   Chicoine, Louis G ^a,b   Young, Tamara L ^b   Reber, Kristina M ^b   Lyons, C Richard ^a   Liu, Yusen ^b   Nelin, Leif D ^a,b,c  

^a UNIVERSITY OF NEW MEXICO HEALTH SCIENCES CENTER   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c THE RESEARCH INSTITUTE AT NATIONWIDE CHILDREN S HOSPITAL   (United States)

Author keywords

Nitric oxide; Pulmonary hypertension; Pulmonary vascular remodeling; Urea

Indexed keywords

ADENOVIRUS VECTOR; ARGINASE; ARGININE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; INDUCIBLE NITRIC OXIDE SYNTHASE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRITE; UREA; VALINE;

ANIMAL CELL; ARTERY ENDOTHELIUM; ARTICLE; CELL PROLIFERATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; COW; DRUG MECHANISM; ENDOTHELIUM CELL; GENE OVEREXPRESSION; GENE TRANSFER; GENETIC TRANSFECTION; NONHUMAN; PRIORITY JOURNAL; PULMONARY ARTERY; UREA CYCLE; VASODILATATION; VIRAL GENE DELIVERY SYSTEM; VIRAL GENE THERAPY; ADENOVIRUS; ANIMAL; BIOSYNTHESIS; CATTLE; CELL CULTURE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; GENE EXPRESSION PROFILING; GENE VECTOR; GENETICS; METABOLISM; VASCULAR ENDOTHELIUM;

ADENOVIRIDAE; ANIMALS; ARGINASE; ARGININE; CATTLE; CELL PROLIFERATION; CELLS, CULTURED; ENDOTHELIUM, VASCULAR; GENE EXPRESSION PROFILING; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; NG-NITROARGININE METHYL ESTER; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; PULMONARY ARTERY; UREA;

EID: 33644848544     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00140.2005     Document Type: Article

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