Adenosine A1 and A2A receptor cross-talk during ageing in the rat myocardium

Experimental Gerontology

Volumn 38, Issue 8, 2003, Pages 855-861

  Arosio, Beatrice ^b   Perlini, Stefano ^c   Calabresi, Carmen ^b   Tozzi, Rossana ^c   Palladini, Giuseppina ^c   Ferrari, Alberto U ^a,c   Vergani, Carlo ^b   Annoni, Giorgio ^a,b  

^a UNIVERSITY OF MILANO BICOCCA   (Italy)

^b FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^c UNIVERSITY OF PAVIA   (Italy)

Author keywords

Adenosine receptor; Ageing; Animal model; Gene expression; Heart

Indexed keywords

ADENOSINE A1 RECEPTOR; ADENOSINE A2A RECEPTOR; MESSENGER RNA;

AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HEART FUNCTION; HEART LEFT VENTRICLE CONTRACTION; HEART LEFT VENTRICLE ENDDIASTOLIC PRESSURE; HEART MUSCLE; HEART RIGHT VENTRICLE; M MODE ECHOCARDIOGRAPHY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SENESCENCE; ANIMAL; ECHOCARDIOGRAPHY; GENETICS; HEART VENTRICLE; METABOLISM; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT;

ANIMALIA;

AGING; ANIMALS; ECHOCARDIOGRAPHY; GENE EXPRESSION; HEART VENTRICLES; MALE; MYOCARDIUM; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR CROSS-TALK; RECEPTOR, ADENOSINE A1; RECEPTOR, ADENOSINE A2A; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 0042206656     PISSN: 05315565     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0531-5565(03)00095-0     Document Type: Article

References (44)

1. Annoni G., Luvarà G., Arosio B., Gagliano N., Fiordaliso F., Santambrogio D., Jeremic G., Mircoli L., Latini R., Vergani C., Masson S. Age-dependent expression of fibrosis-related genes and collagen deposition in the rat myocardium. Mech. Ageing Dev. 101:1998;57-72.
2. Anversa P., Li P., Sonnenblick E.H., Olivetti G. Effects of aging on quantitative structural properties of coronary vasculature and microvasculature in rats. Am. J. Physiol. 267:1994;H1062-H1073.
3. Belardinelli L., Linden J., Berne R.M. The cardiac effects of adenosine. Prog. Cardiovasc. Dis. 32:1989;73-97.
4. 1 receptor and Gα protein coupling in rat ventricular myocardium during aging. Circ. Res. 81:1997;1065-1071.
5. 2A receptor in the modulation of myocardial reperfusion damage. J. Cardiovasc. Pharmacol. 33:1999;883-893.
6. Chien K.R., Knowlton K.U., Zhu H., Chien S. Regulation of cardiac gene expression during myocardial growth and hypertrophy: molecular studies of an adaptative physiologic response. FASEB J. 5:1991;3037-3046.
7. Chomczynski P., Sacchi N. Single-step method of RNA isolation by acid guanidinium thyocyanate-phenol-chloroform extraction. Anal. Biochem. 162:1987;156-159.
8. Chung E.S., Perlini S., Fenton R.A., Dobson J.G., Meyer T.E. Effects of chronic adenosine uptake blockade on adrenergic responsiveness and left ventricular chamber function in pressure overload hypertrophy in the rat. J. Hypertens. 16:1998;1813-1822.
9. 1 receptor binding sites in the rat brain. Eur. J. Biochem. 268:2001;2939-2947.
10. Di Gennaro M., Bernabei R., Sgadari A., Carosella L., Carboni P.U. Age-related differences in isolated rat sinus node function. Basic Res. Cardiol. 82:1987;530-536.
11. Dixon A.K., Gubitz A.K., Sirinathsinghji D.J.S., Richardons P.J., Freeman T.C. Tissue distribution of adenosine receptor mRNAs in the rat. Br. J. Pharmacol. 118:1996;1461-1468.
12. Dobson J.G., Fenton R.A. Adenosine inhibition of β-adrenergic-induced responses in aged hearts. Am. J. Physiol. Heart Circ. Physiol. 265:1993;H494-H503.
13. Dobson J.G., Ordway R.W., Fenton R.A. Endogenous adenosine inhibits catecholamine contractile responses in normoxic hearts. Am. J. Physiol. 251:1986;H455-H462.
14. Dobson J.G., Fenton R.A., Romano F.D. Increased myocardial adenosine production and reduction of β-adrenergic contractile response in aged hearts. Circ. Res. 66:1990;1381-1390.
15. Duckles S.P., Banner W. Changes in vascular smooth muscle reactivity during development. Annu. Rev. Pharmacol. Toxicol. 24:1984;65-83.
16. Fleisch J.H. Age-related changes in the sensitivity of blood vessels to drugs. Pharmacol. Ther. 8:1980;477-487.
17. Ford G.A., Hoffman B.B., Vestal R.E., Blascheke T.F. Age-related changes in adenosine β-responsiveness of vascular smooth muscle in man. Br. J. Clin. Pharmacol. 33:1992;83-87.
18. 1 receptor function in the rat heart. J. Mol. Cell. Cardiol. 298:1997;593-602.
19. 1 receptor function in the heart are attenuated by dietary restriction. J. Pharmacol. Exp. Ther. 285:1998;186-192.
20. Headrick J.P. Impact of aging on adenosine levels, A1/A2 responses, arhythmogenesis, and henergy metabolism in rat heart. Am. J. Physiol. Heart Circ. Physiol. 270:1996;H897-H906.
21. Lakatta E.G. Cardiac muscle changes in senescence. Annu. Rev. Physiol. 49:1987;519-531.
22. Lakatta E.G., Yin F.C.P. Myocardial aging: functional alterations and related cellular mechanism. Am. J. Physiol. 242:1982;C1-C9.
23. Lerman B.B., Belardinelli L. Cardiac electrophysiology of adenosine: basic and clinical concepts. Circulation. 83:1991;1499-1509.
24. Lompre A.M., Mercadier J.J., Schwarts K. Changes in gene expression during cardiac growth. Int. Rev. Cytol. 124:1991;137-186.
25. Matherne G.P., Byford A.M., Gilrain J.T., Dalkin A.C. Changes in myocardial A1 adenosine receptor and message levels during fetal development and postnatal maturation. Biol. Neonate. 70:1996;199-205.
26. Meyer T.E., Chung E.S., Perlini S., Norton G.R., Woodiwiss A.J., Lorbar M., Fenton R.A., Dobson J.G. Pressure-overload hypertrophy is associated with attenuated adenosine A1 receptor-mediated antiadrenergic signaling. Hypertension. 37:2001;862-868.
27. 2a receptor activation in rat heart. Am. J. Physiol. 276:1999;H341-H349.
28. Olivetti G., Melissari M., Capasso J.M., Anversa P. Cardiomyopathy of the aging human heart. Myocyte loss and reactive cellular hypertrophy. Circ. Res. 68:1991;1560-1568.
29. Olivetti G., Melissari M., Balbi T., Quaini F., Cigola E., Sonnenblick E.H., Anversa P. Myocyte cellular hypertrophy is responsible for ventricular remodelling in the hypertrophyed heart of middle aged individuals in absences of cardiac failure. Cardiovasc. Res. 28:1994;1199-1208.
30. Pan H.Y.M., Hoffman B.B., Pershe R.A., Blascheke T.F. Decline in beta adrenergic receptor-mediated vascular relaxation with aging in man. J. Pharmacol. Exp. Ther. 239:1986;802-807.
31. Peralta C., Hotter G., Closa D., Gelpi E., Bulbena O., Rosello-Catafau J. Protective effect of preconditioning on the injury associated to hepatic ischemia-reperfusion in the rat: role of nitric oxide and adenosine. Hepatology. 25:1997;934-937.
32. Perlini S., Khouri E.P., Chung E.S., Norton G.R., Fenton R.A., Dobson J.G., Meyer T.E. Adenosine mediates sustained adrenergic desensitization in the rat heart via activation of protein kinase C. Circ. Res. 83:1998;761-771.
33. Perlini S., Arosio B., Vandoni P., Santambrogio D., Gagliano N., Chung E.S., Palladini G., Parmeggiani L., Annoni G., Meyer T.E., Ferrari A.U. Gene expression of myocardial adenosine-A1 receptor increases in compensated pressure-overload hypertrophy but decreases when the left ventricle fails. Circulation 99. 1999;I-271.
34. Rongen G.A., Lenders J.W.M., Lambrou J., Willemsen J., Van Belle H., Thien T., Smits P. Presynaptic inhibition of norepinephrine release from sympathetic nerve endings by endogenous adenosine. Hypertension. 27:1996;933-938.
35. Sahn D.J., DeMaria A., Kisslo J., Weyman A. Recommendations regarding quantitation in M-mode echocardiography: results of a survery of echocardiographic measurements. Circulation. 58:1978;1072-1083.
36. Schiffman S.N., Vanderhaegen J.J. Age-related loss of mRNA encoding adenosine A2 receptor in the rat striatum. Neurosci. Lett. 158:1993;121-124.
37. 2-receptor activation at reperfusion reduces infarct size and improves myocardial wall function in dog heart. J. Cardiovasc. Pharmacol. 101:1993;746-752.
38. Schulman D., Latchman D.S., Yellon D.M. Effect of aging on the ability of preconditioning to protect rat hearts from ischemia-reperfusion injury. Am. J. Physiol. Heart Circ. Physiol. 281:(4):2001;H1630-H1636.
39. Shryock J.C., Belardinelli L. Adenosine and adenosine receptors in the cardiovascular system: biochemistry, physiology, and pharmacology. Am. J. Cardiol. 79:(12A):1997;2-10.
40. Swynghedauw B., Besse S., Assayag P., Carrè F., Chevalier B., Charlemagne D., Delcayre C., Hardouin S., Heymes C., Moalic J.M. Molecular and cellular biology of the senescent hypertrophied and failing heart. Am. J. Cardiol. 76:1995;2D-7D.
41. Vestal R.E., Wood A.J.J., Shand D.G. Reduced β-adrenoceptor sensitivity in the elderly. Clin. Pharmacol. Ther. 26:1979;181-186.
42. Vinten-Johansen J., Zhao Z.Q., Sato H. Reduction in surgical ischemic-reperfusion injury with adenosine and nitric-oxide therapy. Ann. Thorac. Surg. 60:1995;852-857.
43. Von Lubitz D.K.J.E., Lin R.C.S., Bischofberger N., Beenhakker M., Boyd M., Lipartowska R., Jacobson K.A. Protection against ischemic damage by adenosine amine conger, a potential and selective adenosine A1 receptor agonist. Eur. J. Pharmacol. 369:(3):1999;313-317.
44. ATP-channel activation. Am. J. Physiol. Heart Circ. Physiol. 273:1997;H1677-H1687.