Lower vitamin-D production from solar ultraviolet-B irradiance may explain some differences in cancer survival rates

Journal of the National Medical Association

Volumn 98, Issue 3, 2006, Pages 357-364

  Grant, William B ^a,b  

^a Sunlight Nutrition and Health Research Center ^*

^b Sunlight   (United States)

Author keywords

Lung cancer; Prostate cancer; Tobacco; Ultraviolet B; Vitamin D

Indexed keywords

25 HYDROXYVITAMIN D; VITAMIN D;

ALCOHOL CONSUMPTION; ARTICLE; BREAST CANCER; CANCER INCIDENCE; CANCER MORTALITY; CANCER STAGING; CANCER SURVIVAL; CAUCASIAN; COLON CANCER; CORRELATIONAL STUDY; DATA ANALYSIS; ESOPHAGUS CANCER; HUMAN; MULTIVARIATE LOGISTIC REGRESSION ANALYSIS; POVERTY; PRIORITY JOURNAL; RECTUM CANCER; RISK REDUCTION; SMOKING; SOLAR RADIATION; STOMACH CANCER; ULTRAVIOLET B RADIATION; URBANIZATION; VITAMIN D METABOLISM;

AFRICAN AMERICANS; EUROPEAN CONTINENTAL ANCESTRY GROUP; HUMANS; NEOPLASMS; RISK FACTORS; SURVIVAL RATE; ULTRAVIOLET RAYS; UNITED STATES; VITAMIN D;

EID: 33644792884     PISSN: 00279684     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (105)

1. Piffath TA, Whiteman MK, Flaws JA, et al. Ethnic differences in cancer mortality trends in the United States, 1950-1992. Ethn Health. 2001;6:105-119.
2. Bach PB, Schrag D, Brawley OW, et al. Survival of blacks and whites after a cancer diagnosis. JAMA. 2002;287:2106-2113.
3. Clegg LX, Li FP, Hankey BF, et al. Cancer survival among U.S. whites and minorities: a SEER (Surveillance, Epidemiology, and End Results) Program population-based study. Arch Intern Med. 2002;162:1985-1993.
4. Jemal A, Clegg LX, Ward E, et al. Annual report to the nation on the status of cancer, 1975-2001, with a special feature regarding survival. Cancer. 2004;101:3-27.
5. Jemal A, Murray T, Ward E, et al. Cancer statistics, 2005. CA Cancer J Clin. 2005;55:10-30.
6. Shavers VL, Brown ML. Racial and ethnic disparities in the receipt of cancer treatment. J Natl Cancer Inst. 2002;94:334-357.
7. Madison T, Schottenfeld D, James SA, et al. Endometrial cancer: socioeconomic status and racial/ethnic differences in stage at diagnosis, treatment, and survival. Am J Public Health. 2004;94:2104-2111.
8. Leistikow B. Lung cancer rates as an index of tobacco smoke exposures: validation against black male approximate non-lung cancer death rates, 1969-2000. Prev Med. 2004;38:511-515.
9. Leistikow BN, Tsodikov A. Cancer death epidemics in United States Black males: Evaluating courses, causation, and cures. Prev Med. 2005;41:380-385.
10. Prout GR Jr, Wesley MN, McCarron PG, et al. Survival experience of black patients and white patients with bladder carcinoma. Cancer. 2004;100:621-630.
11. O'Malley CD, Le GM, Glaser SL, et al. Socioeconomic status and breast carcinoma survival in four racial/ethnic groups: a population-based study. Cancer. 2003;97:1303-1311.
12. Polednak AP. Racial differences in mortality from obesity-related chronic diseases in U.S. women diagnosed with breast cancer. Ethn Dis. 2004;14:463-468
13. Chlebowski RT, Chen Z, Anderson GL, et al. Ethnicity and breast cancer; factors influencing differences in incidence and outcome. J Natl Cancer Inst. 2005;97:439-448.
14. Newman LA. Breast carcinoma in African-American and White women: application of molecular biology to understand outcome disparities. Cancer. 2004;101:1261-1263.
15. Rosenberg J, Chia YL, Plevritis S. The effect of age, race, tumor size, tumor grade, and disease stage on invasive ductal breast cancer survival in the U.S. SEER database. Breast Cancer Res Treat. 2005;89:47-54.
16. Garner EI. Cervical cancer: disparities in screening, treatment, and survival. Cancer Epidemiol Biomarkers Prev. 2003;12:242s-247s
17. Patel DA, Barnholtz-Sloan JS, et al. A population-based study of racial and ethnic differences in survival among women with invasive cervical cancer: analysis of Surveillance, Epidemiology, and End Results data. Gynecol Oncol. 2005;97:550-558.
18. Slattery ML, Samowtiz W, Ma K, et al. CYP1A1, cigarette smoking, and colon and rectal cancer. Am J Epidemiol. 2004;160:842-852.
19. Tammemagi CM, Neslund-Dudas C, Simoff M, et al. Lung carcinoma symptoms-an independent predictor of survival and an important mediator of African-American disparity in survival. Cancer. 2004;101:1655-1663.
20. Tomar SL, Loree M, Logan H. Racial differences in oral and pharyngeal cancer treatment and survival in Florida. Cancer Causes Control. 2004;15:601-609.
21. Barnholtz-Sloan JS, Tainsky MA, Abrams J, et al. Ethnic differences in survival among women with ovarian carcinoma. Cancer. 2002;94:1886-1893.
22. Biggs ML, Schwartz SM. Differences in testis cancer survival by race and ethnicity: a population-based study, 1973-1999 (United States). Cancer Causes Control. 2004;15:437-444.
23. Sherman ME, Devesa SS. Analysis of racial differences in incidence, survival, and mortality for malignant tumors of the uterine corpus. Cancer. 2003;98:176-186.
24. Miller JA, Rege RV, Ko CY, et al. Health care access and poverty do not explain the higher esophageal cancer mortality in African Americans. Am J Surg. 2004;188:22-26.
25. Steyerberg EW, Earle CC, Neville BA, et al. Racial differences in surgical evaluation, treatment, and outcome of locoregional esophageal cancer: a population-based analysis of elderly patients. J Clin Oncol. 2005;23:510-517.
26. Reddy S, Shapiro M, Morton R Jr, et al. Prostate cancer in black and white Americans. Cancer Metastasis Rev. 2003;22:83-86.
27. Gilligan T. Social disparities and prostate cancer: mapping the gaps in our knowledge. Cancer Causes Control. 2005;16:45-53.
28. Dignam JJ, Redmond CK, Fisher B, et al. Prognosis among African-American women and white women with lymph node negative breast carcinoma: findings from two randomized clinical trials of the National Surgical Adjuvant Breast and Bowel Project (NSABP). Cancer. 1997;80:80-90.
29. Rex DK, Rawl SM, Rabeneck L, et al. Colorectal cancer in African Americans. Rev Gastroenterol Disord. 2004;4:60-65.
30. Garland CF, Garland FC. Do sunlight and vitamin D reduce the likelihood of colon cancer? Int J Epidemiol. 1980;9:227-231.
31. Garland C, Shekelle RB, Barrett-Connor E, et al. Dietary vitamin D and calcium and risk of colorectal cancer: a 19-year prospective study in men. Lancet. 1985;1:307-309.
32. Grant WB. An estimate of premature cancer mortality in the United States due to inadequate doses of solar ultraviolet-B radiation. Cancer. 2002;94:1867-1875.
33. Grant WB. Benefits of UVB exposure to reduce the risk of cancer-ecologic studies of cancer mortality rates. Proceedings of the CIE Symposium '04; Light and Health: non-visual effects, 30 Sep.-2 Oct. 2004, Commission International de L'Eclairage, Vienna, Austria, 2004:174-177.
34. Giovannucci E. The role of vitamin D in cancer incidence and prevention. American Association for Cancer Research Annual Meeting. 2005.
35. van den Bemd GJ, Chang GT. Vitamin D and vitamin D analogs in cancer treatment. Curr Drug Targets. 2002;3:85-94.
36. Lamprecht SA, Lipkin M. Chemoprevention of colon cancer by calcium, vitamin D and folate: molecular mechanisms. Nat Rev Cancer. 2003;3:601-614.
37. Robsahm TE, Tretli S, Dahlback A, et al. Vitamin D3 from sunlight may improve the prognosis of breast-, colon- and prostate cancer (Norway). Cancer Causes Control. 2004;15:149-158.
38. Moan J, Porojnicu AC, Robsahm TE, et al, Solar radiation, vitamin D and survival rate of colon cancer in Norway. J Photochem Photobiol B. 2005;78:189-193.
39. Zhou W, Suk R, Liu G, et al. Vitamin D is associated with improved survival in early stage non-small cell lung cancer patients. Cancer Epidemiol Biomarkers Prev. 2005;14:2303-2309.
40. Matsuoka LY, Wortsman J, Chen TC, et al. Compensation for the interracial variance in the cutaneous synthesis of vitamin D. J Lab Clin Med. 1995;126:452-457.
41. Harris SS, Dawson-Hughes B. Seasonal changes in plasma 25-hydroxyvitamin D concentrations of young American black and white women. Am J Clin Nutr. 1998;67:1232-1236.
42. Looker AC, Dawson-Hughes B, Calvo MS, et al. Serum 25-hydroxyvitamin D status of adolescents and adults in two seasonal subpopulations from NHANES III. Bone. 2002;30:771-777.
43. Harris SS, Soteriades E, Coolidge JA, et al. Vitamin D insufficiency and hyperparathyroidism in a low income, multiracial, elderly population. J Clin Endocrinol Metab. 2000;85:4125-4130.
44. Harkness LS, Cromer BA. Vitamin D deficiency in adolescent females. J Adolesc Health. 2005;37:75.
45. Dawson-Hughes B. Racial/ethnic considerations in making recommendations for vitamin D for adult and elderly men and women. Am J Clin Nutr. 2004;80:1763S-1766S.
46. Studzinski GP, Moore DC. Sunlight-can it prevent as well as cause cancer? Cancer Res. 1995;55:4014-4022.
47. Giovannucci E. The epidemiology of vitamin D and cancer incidence and mortality: a review (United States). Cancer Causes Control. 2005;16:83-95.
48. Corder EH, Friedman GD, Vogelman JH, et al. Seasonal variation in vitamin D, vitamin D-binding protein, and dehydroepiandrosterone: risk of prostate cancer in black and white men. Cancer Epidemiol Biomarkers Prev. 1995;4:655-659.
49. Ingles SA, Coetzee GA, Ross RK, et al. Association of prostate cancer with vitamin D receptor haplotypes in African-Americans. Cancer Res. 1998;58:1620-1623.
50. Platz EA, Rimm EB, Willett WC, et al. Racial variation in prostate cancer incidence and in hormonal system markers among male health professionals. J Natl Cancer Inst. 2000;92:2009-2017.
51. Hu S, Ma F, Collado-Mesa F, et al. Ultraviolet radiation and incidence of non-Hodgkin's lymphoma among Hispanics in the United States. Cancer Epidemiol Biomarters Prev. 2004;13:59-64.
52. Morgenstern H. Ecologic studies. In: Rothman KJ, Greenland S, eds. Modern Epidemiology, 2nd ed. Lippincort, Philadelphia, 1998:459-480.
53. Greenland S. Ecologic versus individual-level sources of confounding in ecologic estimates of contextual health effects. Int J Epidemiol. 2001;30:1343-1350.
54. Hill AB. The environment and disease: association or causation? Proc R Soc Wed. 1965;58:295-300.
55. Weed DL. Environmental epidemiology: basics and proof of cause-effect. Toxicology. 2002;181-182:399-403.
56. Devesa SS, Grauman DJ, Blot WJ, et al. Atlas of Cancer Mortality in the United States, 1950-1994. NIH Publication No. 99-4564, 1999. http://cancer. gov/atlasplus/new.html. Accessed 01/22/06.
57. Holick MF. Photosynthesis of vitamin D in the skin: effect of environmental and life-style variables. Fed Proc. 1987;46:1876-1882.
58. Leffell DJ, Brash DE. Sunlight and skin cancer. Sci Am. 1996;275:52-53, 56-59. http://toms.gsfc.nasa.gov/ery_uv/dna_exp.gif. Accessed 01/22/06.
59. Lubin D, Jensen EH, Gies HP. Global surface ultraviolet radiation climatology from TOMS and ERBE data. J Geophys Res-Atmos. 1998;103:26061-26091.
60. Kimlin MG. The climatology of Vitamin D producing ultraviolet radiation over the United States. J Steroid Biochem Mol Biol. 2004;89-90:479-483.
61. Bigelow DS, Slusser JR, Beaubien AF, et al. The USDA Ultraviolet Radiation Monitoring Program. Bull Amer Meteorol Soc. 1998;79:601-615.
62. Giovino GA, Schooley MW, Zhu BP, et al. Surveillance for selected tobacco-use behaviors-United States, 1900-1994. MMWR CDC Surveill Summ. 1994;43:1-43.
63. Cresanta JL. Epidemiology of cancer in the United States. Prim Care. 1992;19:419-441.
64. Nephew TM, Williams GD, Yi H, et al. Surveillance Report #59: Apparent Per Capita Alcohol Consumption: National, State, and Regional Trends, 1977-99. Washington, DC: NIAAA, 2002. http://pubs.niaaa.nih.gov/publications/ surveillance66/CONS_02.pdf. Accessed 01/22/06.
65. Urban and Rural Populations: 1900-1990. Source: 1990 Census of Population and Housing, "1990 Population and Housing Unit Counts: United States", (CPH-2); and 1980 PC80-1-1. www.census.gov/population/census-data/ urpop0090.txt. Accessed 01/22/06.
66. Freedman DM, Dosemeci M, McGlynn K. Sunlight and mortality from breast, ovarian, colon, prostate, and non-melanoma skin cancer: a composite death certificate based case-control study. Occup Environ Med. 2002;51:257-262.
67. Krieger N, Quesenberry C Jr, Peng T, et al. Social class, race/ethnicity, and incidence of breast, cervix, colon, lung, and prostate cancer among Asian, Black, Hispanic, and White residents of the San Francisco Bay Area, 1988-92 (United States). Cancer Causes Control. 1999;10:525-537.
68. Baquet CR, Commiskey P. Socioeconomic factors and breast carcinoma in multicultural women. Cancer. 2000;88:1256-1264.
69. Nilunger L, Diderichsen F, Burstrom B, et al. Using risk analysis in Health Impact Assessment: the impact of different relative risks for men and women in different socio-economic groups. Health Policy. 2004;67:215-224.
70. Gordon NH. Socioeconomic factors and breast cancer in black and white Americans. Cancer Metastasis Rev. 2003;22:55-65.
71. U.S. Census Bureau. Census Historical Poverty Tables. CPH-L-162. Persons by Poverty Status in 1969, 1979, and 1989, by State, www.census.gov/hhes/ poverty/census/cphll62.html. Accessed 01/22/06.
72. SPSS 13.0 Brief Guide. SPSS Inc. Chicago. 2004.
73. Guirgis HA, Lynch HT, Harris RE, et al. Carcinoembryonic antigen (CEA) in the cancer family syndrome. Cancer. 1978;42:1574-1578.
74. Karagas MR, Park S, Warren A, et al. Gender, smoking, glutathione-S-transferase variants and bladder cancer incidence: a population-based study. Cancer Lett. 2005;219:63-69.
75. Johnson KC. Accumulating evidence on passive and active smoking and breast cancer risk. Int J Cancer. 2005;117:619-628.
76. Pan SY, Ugnat AM, Mao Y, et al. Association of cigarette smoking with the risk of ovarian cancer. Int J Cancer. 2004;111:124-130.
77. Hu J, Ugnat AM, Canadian Cancer Registries Epidemiology Research Group. Active and passive smoking and risk of renal cell carcinoma in Canada. Eur J Cancer. 2005;41:770-778.
78. Jablonski NG, Chaplin G. The evolution of human skin coloration. J Hum. Evol. 2000;39:57-106.
79. Bell NH, Jackson GJ. Role of vitamin D in the pathogenesis and treatment of osteoporosis. Endocr Pract. 1995;1:44-47.
80. Tuohimaa P, Tenkanen L, Ahonen M, et al. Both high and low levels of blood vitamin D are associated with a higher prostate cancer risk: a longitudinal, nested case-control study in the Nordic countries. Int J Cancer. 2004;108:104-108.
81. Grant WB. Geographic variation of prostate cancer mortality rates in the United States: Implications for prostate cancer risk related to vitamin D. Int J Cancer. 2004;111:470-471.
82. Tuohimaa P, Golovko O, Kalueff A, et al. Calcidiol and prostate cancer. J Steroid Biochem Mol Biol. 2005;93:183-190.
83. Grant WB, Garland CF. A critical review of studies on vitamin D in relation to colorectal cancer. Nutr Cancer. 2004;48:115-123.
84. Heaney RP. Long-latency deficiency disease: insights from calcium and vitamin D. Am J Clin Nutr. 2003;78:912-919.
85. Holick MF. Vitamin D: a millennium perspective. J Cell Biochem. 2003;88:296-307.
86. Embry A. Vitamin D supplementation in the fight against multiple sclerosis. J Orthomolec Med. 2004;19:27-38. www.sunarc.org/Embry-_JOM_Vit_D-I. pdf. Accessed 06/01/05.
87. Holick MF. Vitamin D: importance in the prevention of cancers, type 1 diabetes, heart disease, and osteoporosis. Am J Clin Nutr. 2004;79:362-371.
88. Holick MF. Sunlight and vitamin D for bone health and prevention of autoimmune diseases, cancers, and cardiovascular disease. Am J Clin Nutr. 2004;80:16785-16885.
89. Dusso AS, Brown AJ, Slatopolsky E. Vitamin D. Am J Physiol Renal Physiol. 2005;289:F8-F28.
90. Mosekilde L. Vitamin D and the elderly. Clin Endocrinol (Oxf). 2005;62:265-281.
91. Peterlik M, Cross HS. Vitamin D and calcium deficits predispose for multiple chronic diseases. Eur J Clin Invest. 2005;35:290-304.
92. Ponsonby AL, Lucas RM, van der Mei IA. A potential role for UVR and Vitamin D in the induction of Multiple Sclerosis, Type 1 Diabetes, Rheumatoid Arthritis. Photochem Photobiol. 2005;81:1267-1275.
93. Grant WB, Holick MF. Benefits and requirements of vitamin D for optimal health: a review. Altern Med Rev. 2005;10:94-111.
94. John EM, Schwartz GG, Koo J, et al. Sun exposure, vitamin D receptor gene polymorphisms, and risk of advanced prostate cancer. Cancer Res. 2005;65:5470-5479.
95. Schwartz GG. Vitamin D and the epidemiology of prostate cancer. Semin Dial. 2005;18:276-289.
96. Bertone-Johnson ER, Chen WY, Holick MF, et al. Plasma 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D and risk of breast cancer. Cancer Epidemiol Biomarkers Prev. 2005;14:1991-1997.
97. Porojnicu AC, Robsahm TE, Ree AH, et al. Season of diagnosis is a prognostic factor in Hodgkin's lymphoma: a possible role of sun-induced vitamin D. Br J Cancer. 2005;93:571-574.
98. Holick MF. Vitamin D: important for prevention of osteoporosis, cardiovascular heart disease, type 1 diabetes, autoimmune diseases, and some cancers. South Med J. 2005;98:1024-1027.
99. Gorham ED, Garland CF, Garland FC, et al. Vitamin D and prevention of colorectal cancer. J Steroid Biochem Mol Biol. 2005;97:179-194.
100. Moon SJ, Fryer AA, Strange RC. Ultraviolet radiation, vitamin d and risk of prostate cancer and other diseases. Photochem Photobiol. 2005;81:1252-1260.
101. Giovannucci E. The epidemiology of vitamin D and colorectal cancer: recent findings. Curr Opin Gastroenterol. 2006;22:24-29.
102. Garland CF, Garland FC, Gorham ED, et al. The Role of Vitamin D in Cancer Prevention. Am J Public Health. 2006;96:252-261.
103. Grant WB, Gorham ED. Time for public health action on vitamin D for cancer risk reduction. Int J Epidemiol. 2005;Nov. 22 [Epub ahead of print]
104. Grant WB. The likely role of vitamin D from solar ultraviolet-B irradiance in increasing cancer survival. Anticancer Res. 2006;26:in press.
105. Grant WB, Garland CF. The association of solar ultraviolet B (UVB) with reducing risk of cancer: multifactorial ecologic analysis of geographic variation in age-adjusted cancer mortality rates. Anticancer Res. 2006;26:in press.