Intradermal and oral immunization with recombinant Mycobacterium bovis BCG expressing the simian immunodeficiency virus Gag protein induces long-lasting, antigen-specific immune responses in guinea pigs

Clinical Immunology

Volumn 119, Issue 1, 2006, Pages 67-78

  Kawahara, Mamoru ^a,b,d   Matsuo, Kazuhiro ^a,c   Honda, Mitsuo ^a,c  

^a NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

^b The Japan Foundation   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

Author keywords

Gag p27; Guinea pig; HIV 1; Human dose; IFN ; Proliferation; Recombinant BCG; SIV

Indexed keywords

BACTERIAL ANTIGEN; BCG VACCINE; GAG PROTEIN; GAMMA INTERFERON; IMMUNOGLOBULIN G; MESSENGER RNA; MYCOBACTERIUM VACCINE; PROTEIN P27; RECOMBINANT VACCINE; TUBERCULIN; VIRUS ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN SPECIFICITY; ARTICLE; BACTERIAL CELL; BACTERIAL INFECTION; CELL CULTURE; CELL PROLIFERATION; CELLULAR IMMUNITY; CONTROLLED STUDY; DELAYED HYPERSENSITIVITY; DISEASE DURATION; FEMALE; GENE EXPRESSION; GENE INSERTION; GUINEA PIG; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMMUNIZATION; INOCULATION; MYCOBACTERIUM BOVIS; NONHUMAN; PRIORITY JOURNAL; SIMIAN IMMUNODEFICIENCY VIRUS; VACCINATION REACTION; VIRUS INFECTION;

ADMINISTRATION, ORAL; ANIMALS; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; FEMALE; GENE EXPRESSION; GENE PRODUCTS, GAG; GENETIC VECTORS; GUINEA PIGS; HIV INFECTIONS; HYPERSENSITIVITY, DELAYED; IMMUNITY, CELLULAR; IMMUNOGLOBULIN G; INJECTIONS, INTRADERMAL; INTERFERON TYPE II; INTESTINES; LEUKOCYTES, MONONUCLEAR; LYMPHOCYTE ACTIVATION; LYMPHOCYTES; MUCOUS MEMBRANE; MYCOBACTERIUM BOVIS; SKIN TESTS; SPLEEN; T-LYMPHOCYTES; TRANSGENES; TUBERCULIN; TUBERCULOSIS; VACCINATION; VACCINES, COMBINED;

EID: 33644784607     PISSN: 15216616     EISSN: 15217035     Source Type: Journal    
DOI: 10.1016/j.clim.2005.11.005     Document Type: Article

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