메뉴 건너뛰기




Volumn 172, Issue 2, 2006, Pages 929-942

The CRAL/TRIO and GOLD domain protein CGR-1 promotes induction of vulval cell fates in Caenorhabditis elegans and interacts genetically with the ras signaling pathway

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN; PROTEIN CGR 1; RAS PROTEIN; UNCLASSIFIED DRUG;

EID: 33644772516     PISSN: 00166731     EISSN: 00166731     Source Type: Journal    
DOI: 10.1534/genetics.104.035550     Document Type: Article
Times cited : (5)

References (61)
  • 1
    • 0026431968 scopus 로고
    • Spatial control of gut-specific gene expression during Caenorhabditis elegans development
    • AAMODT, E. J., M. A. CHUNG and J. D. MCGHEE, 1991 Spatial control of gut-specific gene expression during Caenorhabditis elegans development. Science 252: 579-582.
    • (1991) Science , vol.252 , pp. 579-582
    • Aamodt, E.J.1    Chung, M.A.2    McGhee, J.D.3
  • 2
    • 0036047057 scopus 로고    scopus 로고
    • The GOLD domain, a novel protein module involved in Golgi function and secretion
    • ANANTHARAMAN, V., and L. ARAVIND, 2002 The GOLD domain, a novel protein module involved in Golgi function and secretion. Genome Biol. 3: 1-7.
    • (2002) Genome Biol. , vol.3 , pp. 1-7
    • Anantharaman, V.1    Aravind, L.2
  • 5
    • 0025226084 scopus 로고
    • Caenorhabditis elegans ras gene let-60 acts as a switch in the pathway of vulval induction
    • BEITEL, G. J., S. G. CLARK and H. R. HORVITZ, 1990 Caenorhabditis elegans ras gene let-60 acts as a switch in the pathway of vulval induction. Nature 348: 503-509.
    • (1990) Nature , vol.348 , pp. 503-509
    • Beitel, G.J.1    Clark, S.G.2    Horvitz, H.R.3
  • 6
    • 0029585636 scopus 로고
    • The Caenorhabditis elegans gene lin-1 encodes an ETS-domain protein and defines a branch of the vulval induction pathway
    • BEITEL, G. J., S. TUCK, I. GREENWALD and H. R. HORVITZ, 1995 The Caenorhabditis elegans gene lin-1 encodes an ETS-domain protein and defines a branch of the vulval induction pathway. Genes Dev. 9: 3149-3162.
    • (1995) Genes Dev. , vol.9 , pp. 3149-3162
    • Beitel, G.J.1    Tuck, S.2    Greenwald, I.3    Horvitz, H.R.4
  • 7
    • 0016063911 scopus 로고
    • The genetics of Caenorhabditis elegans
    • BRENNER, S., 1974 The genetics of Caenorhabditis elegans. Genetics 77: 71-94.
    • (1974) Genetics , vol.77 , pp. 71-94
    • Brenner, S.1
  • 8
    • 0036102081 scopus 로고    scopus 로고
    • Zinc ions and cation diffusion facilitator proteins regulate Ras-mediated signaling
    • BRUINSMA, J. J., T. JIRAKULAPORN, A. J. MUSLIN and K. KORNFELD, 2002 Zinc ions and cation diffusion facilitator proteins regulate Ras-mediated signaling. Dev. Cell 2: 567-578.
    • (2002) Dev. Cell , vol.2 , pp. 567-578
    • Bruinsma, J.J.1    Jirakulaporn, T.2    Muslin, A.J.3    Kornfeld, K.4
  • 9
    • 0018644948 scopus 로고
    • Effects of a supernatant protein activator on microsomal squalene-2,3-oxide-lanosterol cyclase
    • CARAS, I. W., and K. BLOCH, 1979 Effects of a supernatant protein activator on microsomal squalene-2,3-oxide-lanosterol cyclase. J. Biol. Chem. 254: 11816-11821.
    • (1979) J. Biol. Chem. , vol.254 , pp. 11816-11821
    • Caras, I.W.1    Bloch, K.2
  • 10
    • 0019332447 scopus 로고
    • Interactions of supernatant protein factor with components of the microsomal squalene epoxidase system. Binding of supernatant protein factor to anionic phospholipids
    • CARAS, I. W., E. J. FRIEDLANDER and K. BLOCH, 1980 Interactions of supernatant protein factor with components of the microsomal squalene epoxidase system. Binding of supernatant protein factor to anionic phospholipids. J. Biol. Chem. 255: 3575-3580.
    • (1980) J. Biol. Chem. , vol.255 , pp. 3575-3580
    • Caras, I.W.1    Friedlander, E.J.2    Bloch, K.3
  • 11
    • 23444431611 scopus 로고
    • Green fluorescent protein as a marker for gene expression
    • CHALFIE, M., Y. TU, G. EUSKIRCHEN,W. W. WARD and D. C. PRASHER, 1994 Green fluorescent protein as a marker for gene expression. Science 263: 802-805.
    • (1994) Science , vol.263 , pp. 802-805
    • Chalfie, M.1    Tu, Y.2    Euskirchen, G.3    Ward, W.W.4    Prasher, D.C.5
  • 12
    • 0030036296 scopus 로고    scopus 로고
    • Isolation and mapping of a human gene (SEC14L), partially homologous to yeast SEC14, that contains a variable number of tandem repeats (VNTR) site in its 3′ untranslated region
    • CHINEN, K., E. TAKAHASHI and Y. NAKAMURA, 1996 Isolation and mapping of a human gene (SEC14L), partially homologous to yeast SEC14, that contains a variable number of tandem repeats (VNTR) site in its 3′ untranslated region. Cytogenet. Cell Genet. 73: 218-223.
    • (1996) Cytogenet. Cell Genet. , vol.73 , pp. 218-223
    • Chinen, K.1    Takahashi, E.2    Nakamura, Y.3
  • 14
    • 0027935308 scopus 로고
    • The Caenorhabditis elegans locus lin-15, a negative regulator of a tyrosine kinase signaling pathway, encodes two different proteins
    • CLARK, S. G., X. LU and H. R. HORVITZ, 1994 The Caenorhabditis elegans locus lin-15, a negative regulator of a tyrosine kinase signaling pathway, encodes two different proteins. Genetics 137: 987-997.
    • (1994) Genetics , vol.137 , pp. 987-997
    • Clark, S.G.1    Lu, X.2    Horvitz, H.R.3
  • 15
    • 0030904503 scopus 로고    scopus 로고
    • Mechanism of activation of the Caenorhabditis elegans ras homologue let-60 by a novel, temperature-sensitive, gain-of-function mutation
    • EISENMANN, D. M., and S. K. KIM, 1997 Mechanism of activation of the Caenorhabditis elegans ras homologue let-60 by a novel, temperature-sensitive, gain-of-function mutation. Genetics 146: 553-565.
    • (1997) Genetics , vol.146 , pp. 553-565
    • Eisenmann, D.M.1    Kim, S.K.2
  • 16
    • 0031685774 scopus 로고    scopus 로고
    • The β-catenin homolog BAR-1 and LET-60 Ras coordinately regulate the Hox gene lin-39 during Caenorhabditis elegans vulval development
    • EISENMANN, D. M., J. N. MALOOF, J. S. SIMSKE, C. KENYON and S. K. KIM, 1998 The β-catenin homolog BAR-1 and LET-60 Ras coordinately regulate the Hox gene lin-39 during Caenorhabditis elegans vulval development. Development 125: 3667-3680.
    • (1998) Development , vol.125 , pp. 3667-3680
    • Eisenmann, D.M.1    Maloof, J.N.2    Simske, J.S.3    Kenyon, C.4    Kim, S.K.5
  • 17
    • 0023090512 scopus 로고
    • A genetic pathway for the specification of the vulval cell lineages of Caenorhabditis elegans
    • FERGUSON, E. L., P. W. STERNBERG and H. R. HORVITZ, 1987 A genetic pathway for the specification of the vulval cell lineages of Caenorhabditis elegans. Nature 326: 259-267.
    • (1987) Nature , vol.326 , pp. 259-267
    • Ferguson, E.L.1    Sternberg, P.W.2    Horvitz, H.R.3
  • 18
    • 0017684545 scopus 로고
    • Purification and properties of a soluble protein activator of rat liver squalene epoxidase
    • FERGUSON, J. B., and K. BLOCH, 1977 Purification and properties of a soluble protein activator of rat liver squalene epoxidase. J. Biol. Chem. 252: 5381-5385.
    • (1977) J. Biol. Chem. , vol.252 , pp. 5381-5385
    • Ferguson, J.B.1    Bloch, K.2
  • 19
    • 0000122573 scopus 로고
    • PHYLIP - Phylogeny inference package (version 3.2)
    • FELSENSTEIN, J., 1989 PHYLIP - phylogeny inference package (version 3.2). Cladistics 5: 164-166.
    • (1989) Cladistics , vol.5 , pp. 164-166
    • Felsenstein, J.1
  • 20
    • 0032545933 scopus 로고    scopus 로고
    • Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
    • FIRE, A., S. XU, M. K. MONTGOMERY, S. A. KOSTAS, S. E. DRIVER et al., 1998 Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans. Nature 391: 806-811.
    • (1998) Nature , vol.391 , pp. 806-811
    • Fire, A.1    Xu, S.2    Montgomery, M.K.3    Kostas, S.A.4    Driver, S.E.5
  • 21
    • 0029935339 scopus 로고    scopus 로고
    • Raf-1 kinase possesses distinct binding domains for phosphatidylserine and phosphatidic acid
    • GHOSH, S., J. C. STRUM, V. A. SCIORRA, L. DANIEL and R. M. BELL, 1996 Raf-1 kinase possesses distinct binding domains for phosphatidylserine and phosphatidic acid. J. Biol. Chem. 271: 8472-8480.
    • (1996) J. Biol. Chem. , vol.271 , pp. 8472-8480
    • Ghosh, S.1    Strum, J.C.2    Sciorra, V.A.3    Daniel, L.4    Bell, R.M.5
  • 22
    • 0037093441 scopus 로고    scopus 로고
    • Activation of Wnt signaling bypasses the requirement for RTK/Ras signaling during C. elegans vulval induction
    • GLEASON, J. E., H. C. KORSWAGEN and D. M. EISENMANN, 2002 Activation of Wnt signaling bypasses the requirement for RTK/Ras signaling during C. elegans vulval induction. Genes Dev. 16: 1281-1290.
    • (2002) Genes Dev. , vol.16 , pp. 1281-1290
    • Gleason, J.E.1    Korswagen, H.C.2    Eisenmann, D.M.3
  • 23
    • 0025316499 scopus 로고
    • Analysis of gain-of-function mutations of the lin-12 gene of Caenorhabditis elegans
    • GREENWALD, I., and G. SEYDOUX, 1990 Analysis of gain-of-function mutations of the lin-12 gene of Caenorhabditis elegans. Nature 346: 197-199.
    • (1990) Nature , vol.346 , pp. 197-199
    • Greenwald, I.1    Seydoux, G.2
  • 24
    • 0027263251 scopus 로고
    • C. elegans lin-45 raf gene participates in let-60 ras-stimulated vulval differentiation
    • HAN, M., A. GOLDEN, Y. HAN and P. W. STERNBERG, 1993 C. elegans lin-45 raf gene participates in let-60 ras-stimulated vulval differentiation. Nature 363: 133-140.
    • (1993) Nature , vol.363 , pp. 133-140
    • Han, M.1    Golden, A.2    Han, Y.3    Sternberg, P.W.4
  • 25
    • 0034175594 scopus 로고    scopus 로고
    • The Caenorhabditis elegans APC-related gene apr-1 is required for epithelial cell migration and Hox gene expression
    • HOIER, E. F., W. A. MOHLER, S. K. KIM and A. HAJNAL, 2000 The Caenorhabditis elegans APC-related gene apr-1 is required for epithelial cell migration and Hox gene expression. Genes Dev. 14: 874-886.
    • (2000) Genes Dev. , vol.14 , pp. 874-886
    • Hoier, E.F.1    Mohler, W.A.2    Kim, S.K.3    Hajnal, A.4
  • 26
    • 0036188791 scopus 로고    scopus 로고
    • Caenorhabditis elegans lin-45 raf is essential for larval viability, fertility and the induction of vulval cell fates
    • HSU, V., C. L. ZOBEL, E. J. LAMBIE, T. SCHEDL and K. KORNFELD, 2002 Caenorhabditis elegans lin-45 raf is essential for larval viability, fertility and the induction of vulval cell fates. Genetics 160: 481-492.
    • (2002) Genetics , vol.160 , pp. 481-492
    • Hsu, V.1    Zobel, C.L.2    Lambie, E.J.3    Schedl, T.4    Kornfeld, K.5
  • 27
    • 0028340308 scopus 로고
    • The lin-15 locus encodes two negative regulators of Caenorhabditis elegans vulval development
    • HUANG, L. S., P. TZOU and P. W. STERNBERG, 1994 The lin-15 locus encodes two negative regulators of Caenorhabditis elegans vulval development. Mol. Biol. Cell 5: 395-411.
    • (1994) Mol. Biol. Cell , vol.5 , pp. 395-411
    • Huang, L.S.1    Tzou, P.2    Sternberg, P.W.3
  • 28
    • 0032819199 scopus 로고    scopus 로고
    • A local, high-density, single-nucleotide polymorphism map used to clone Caenorhabditis elegans cdf-1
    • JAKUBOWSKI, J., and K. KORNFELD, 1999 A local, high-density, single-nucleotide polymorphism map used to clone Caenorhabditis elegans cdf-1. Genetics 153: 743-752.
    • (1999) Genetics , vol.153 , pp. 743-752
    • Jakubowski, J.1    Kornfeld, K.2
  • 29
    • 0030116297 scopus 로고    scopus 로고
    • Large scale analysis of C. elegans cDNA
    • in Japanese
    • KOHARA, Y., 1996 Large scale analysis of C. elegans cDNA. Tanpakushitsu Kakusan Koso 41: 715-720 (in Japanese).
    • (1996) Tanpakushitsu Kakusan Koso , vol.41 , pp. 715-720
    • Kohara, Y.1
  • 30
    • 0031081140 scopus 로고    scopus 로고
    • Vulval development in Caenorhabditis elegans
    • KORNFELD, K., 1997 Vulval development in Caenorhabditis elegans. Trends Genet. 13: 55-61.
    • (1997) Trends Genet. , vol.13 , pp. 55-61
    • Kornfeld, K.1
  • 31
    • 0028947528 scopus 로고
    • The Caenorhabditis elegans gene mek-2 is required for vulval induction and encodes a protein similar to the protein kinase MEK
    • KORNFELD, K., K. L. GUAN and H. R. HORVITZ, 1995a The Caenorhabditis elegans gene mek-2 is required for vulval induction and encodes a protein similar to the protein kinase MEK. Genes Dev. 9: 756-768.
    • (1995) Genes Dev. , vol.9 , pp. 756-768
    • Kornfeld, K.1    Guan, K.L.2    Horvitz, H.R.3
  • 32
    • 0029588204 scopus 로고
    • The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans
    • KORNFELD, K., D. B. HOM and H. R. HORVITZ, 1995b The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans. Cell 83: 903-913.
    • (1995) Cell , vol.83 , pp. 903-913
    • Kornfeld, K.1    Hom, D.B.2    Horvitz, H.R.3
  • 33
    • 0028107517 scopus 로고
    • A MAP kinase homolog, mpk-1, is involved in rasmediated induction of vulval cell fates in Caenorhabditis elegans
    • LACKNER, M. R., K. KORNFELD, L. M. MILLER, H. R. HORVITZ and S. K. KIM, 1994 A MAP kinase homolog, mpk-1, is involved in rasmediated induction of vulval cell fates in Caenorhabditis elegans. Genes Dev. 8: 160-173.
    • (1994) Genes Dev. , vol.8 , pp. 160-173
    • Lackner, M.R.1    Kornfeld, K.2    Miller, L.M.3    Horvitz, H.R.4    Kim, S.K.5
  • 34
    • 0033166740 scopus 로고    scopus 로고
    • Interactions of c-Raf-1 with phosphatidylserine and 14-3-3
    • MCPHERSON, R. A., A. HARDING, S. ROY, A. LANE and J. F. HANCOCK, 1999 Interactions of c-Raf-1 with phosphatidylserine and 14-3-3. Oncogene 18: 3862-3869.
    • (1999) Oncogene , vol.18 , pp. 3862-3869
    • McPherson, R.A.1    Harding, A.2    Roy, S.3    Lane, A.4    Hancock, J.F.5
  • 35
    • 0025942107 scopus 로고
    • Efficient gene transfer in C. elegans: Extrachromosomal maintenance and integration of transforming sequences
    • MELLO, C. C., J. M. KRAMER, D. STINCHCOMB and V. AMBROS, 1991 Efficient gene transfer in C. elegans: extrachromosomal maintenance and integration of transforming sequences. EMBO J. 10: 3959-3970.
    • (1991) EMBO J. , vol.10 , pp. 3959-3970
    • Mello, C.C.1    Kramer, J.M.2    Stinchcomb, D.3    Ambros, V.4
  • 36
    • 0027196007 scopus 로고
    • lin-31, a Caenorhabditis elegans HNF-3/fork head transcription factor homolog, specifies three alternative cell fates in vulval development
    • MILLER, L. M., M. E. GALLEGOS, B. A. MORISSEAU and S. K. KIM, 1993 lin-31, a Caenorhabditis elegans HNF-3/fork head transcription factor homolog, specifies three alternative cell fates in vulval development. Genes Dev. 7: 933-947.
    • (1993) Genes Dev. , vol.7 , pp. 933-947
    • Miller, L.M.1    Gallegos, M.E.2    Morisseau, B.A.3    Kim, S.K.4
  • 37
    • 0034530133 scopus 로고    scopus 로고
    • Null mutations in the lin-31 gene indicate two functions during Caenorhabditis elegans vulval development
    • MILLER, L. M., H. A. HESS, D. B. DOROQUEZ and N. M. ANDREWS, 2000 Null mutations in the lin-31 gene indicate two functions during Caenorhabditis elegans vulval development. Genetics 156: 1595-1602.
    • (2000) Genetics , vol.156 , pp. 1595-1602
    • Miller, L.M.1    Hess, H.A.2    Doroquez, D.B.3    Andrews, N.M.4
  • 38
    • 0033179969 scopus 로고    scopus 로고
    • Yeast Sec14p deficient in phosphatidylinositol transfer activity is functional in vivo
    • PHILLIPS, S. E., B. SHA, L. TOPALOF, Z. XIE, J. G. ALB et al., 1999 Yeast Sec14p deficient in phosphatidylinositol transfer activity is functional in vivo. Mol. Cell 4: 187-197.
    • (1999) Mol. Cell , vol.4 , pp. 187-197
    • Phillips, S.E.1    Sha, B.2    Topalof, L.3    Xie, Z.4    Alb, J.G.5
  • 41
    • 0032576758 scopus 로고    scopus 로고
    • Crystal structure of the Saccharomyces cerevisiae phosphatidylinositoltransfer protein
    • SHA, B., S. E. PHILLIPS, V. A. BANKAITIS and M. LUO, 1998 Crystal structure of the Saccharomyces cerevisiae phosphatidylinositoltransfer protein. Nature 391: 506-510.
    • (1998) Nature , vol.391 , pp. 506-510
    • Sha, B.1    Phillips, S.E.2    Bankaitis, V.A.3    Luo, M.4
  • 42
    • 0035956912 scopus 로고    scopus 로고
    • Supernatant protein factor, which stimulates the conversion of squalene to lanosterol, is a cytosolic squalene transfer protein and enhances cholesterol biosynthesis
    • USA
    • SHIBATA, N., M. ARITA, Y. MISAKI, N. DOHMAE, K. TAKIO et al., 2001 Supernatant protein factor, which stimulates the conversion of squalene to lanosterol, is a cytosolic squalene transfer protein and enhances cholesterol biosynthesis. Proc. Natl. Acad. Sci. USA 98: 2244-2249.
    • (2001) Proc. Natl. Acad. Sci. , vol.98 , pp. 2244-2249
    • Shibata, N.1    Arita, M.2    Misaki, Y.3    Dohmae, N.4    Takio, K.5
  • 43
    • 0032504106 scopus 로고    scopus 로고
    • SUR-8, a conserved Rasbinding protein with leucine-rich repeats, positively regulates Ras-mediated signaling in C. elegans
    • SIEBURTH, D. S., Q. SUN and M. HAN, 1998 SUR-8, a conserved Rasbinding protein with leucine-rich repeats, positively regulates Ras-mediated signaling in C. elegans. Cell 94: 119-130.
    • (1998) Cell , vol.94 , pp. 119-130
    • Sieburth, D.S.1    Sun, Q.2    Han, M.3
  • 44
    • 0033214325 scopus 로고    scopus 로고
    • A PP2A regulatory subunit positively regulates Ras-mediated signaling during Caenorhabditis elegans vulval induction
    • SIEBURTH, D. S., M. SUNDARAM, R. M. HOWARD and M. HAN, 1999 A PP2A regulatory subunit positively regulates Ras-mediated signaling during Caenorhabditis elegans vulval induction. Genes Dev. 13: 2562-2569.
    • (1999) Genes Dev. , vol.13 , pp. 2562-2569
    • Sieburth, D.S.1    Sundaram, M.2    Howard, R.M.3    Han, M.4
  • 45
    • 0029160169 scopus 로고
    • sur-2, a novel gene, functions late in the let-60 ras-mediated signaling pathway during Caenorhabditis elegans vulval induction
    • SINGH, N., and M. HAN, 1995 sur-2, a novel gene, functions late in the let-60 ras-mediated signaling pathway during Caenorhabditis elegans vulval induction. Genes Dev. 9: 2251-2265.
    • (1995) Genes Dev. , vol.9 , pp. 2251-2265
    • Singh, N.1    Han, M.2
  • 46
    • 0035976927 scopus 로고    scopus 로고
    • Identification and characterization of a novel Golgi protein, GCP60, that interacts with the integral membrane protein giantin
    • SOHDA, M., Y. MISUMI, A. YAMAMOTO, A. YANO, N. NAKAMURA et al., 2001 Identification and characterization of a novel Golgi protein, GCP60, that interacts with the integral membrane protein giantin. J. Biol. Chem. 276: 45298-45306.
    • (2001) J. Biol. Chem. , vol.276 , pp. 45298-45306
    • Sohda, M.1    Misumi, Y.2    Yamamoto, A.3    Yano, A.4    Nakamura, N.5
  • 47
    • 0030925920 scopus 로고    scopus 로고
    • Pfam: A comprehensive database of protein domain families based on seed alignments
    • SONNHAMMER, E. L., S. R. EDDY and R. DURBIN, 1997 Pfam: a comprehensive database of protein domain families based on seed alignments. Proteins 3: 405-420.
    • (1997) Proteins , vol.3 , pp. 405-420
    • Sonnhammer, E.L.1    Eddy, S.R.2    Durbin, R.3
  • 48
    • 0031767247 scopus 로고    scopus 로고
    • Genetics of RAS signaling in C. elegans
    • STERNBERG, P. W., and M. HAN, 1998 Genetics of RAS signaling in C. elegans. Trends Genet. 14: 466-472.
    • (1998) Trends Genet. , vol.14 , pp. 466-472
    • Sternberg, P.W.1    Han, M.2
  • 50
    • 0041324941 scopus 로고    scopus 로고
    • Supernatant protein factor in complex with RRR-alpha-tocopherylquinone: A link between oxidized vitamin E and cholesterol biosynthesis
    • STOCKER, A., and U. BAUMANN, 2003 Supernatant protein factor in complex with RRR-alpha-tocopherylquinone: a link between oxidized vitamin E and cholesterol biosynthesis. J. Mol. Biol. 332: 759-765.
    • (2003) J. Mol. Biol. , vol.332 , pp. 759-765
    • Stocker, A.1    Baumann, U.2
  • 51
    • 0036849751 scopus 로고    scopus 로고
    • Crystal structure of the human supernatant protein factor
    • STOCKER, A., T. TOMIZAKI, C. SCHULZE-BRIESE and U. BAUMANN, 2002 Crystal structure of the human supernatant protein factor. Structure 10: 1533-1540.
    • (2002) Structure , vol.10 , pp. 1533-1540
    • Stocker, A.1    Tomizaki, T.2    Schulze-Briese, C.3    Baumann, U.4
  • 52
    • 0029559183 scopus 로고
    • The C. elegans ksr-1 gene encodes a novel Raf-related kinase involved in Ras-mediated signal transduction
    • SUNDARAM, M., and M. HAN, 1995 The C. elegans ksr-1 gene encodes a novel Raf-related kinase involved in Ras-mediated signal transduction. Cell 83: 889-901.
    • (1995) Cell , vol.83 , pp. 889-901
    • Sundaram, M.1    Han, M.2
  • 53
    • 0032524912 scopus 로고    scopus 로고
    • MAP kinase signaling specificity mediated by the LIN-1 Ets/LIN-31 WH transcription factor complex during C. elegans vulval induction
    • TAN, P. B., M. R. LACKNER and S. K. KIM, 1998 MAP kinase signaling specificity mediated by the LIN-1 Ets/LIN-31 WH transcription factor complex during C. elegans vulval induction. Cell 93: 569-580.
    • (1998) Cell , vol.93 , pp. 569-580
    • Tan, P.B.1    Lackner, M.R.2    Kim, S.K.3
  • 54
    • 0001185242 scopus 로고
    • On the conversion of squalene to lanosterol in vitro
    • TCHEN, T. T., and K. BLOCH, 1957 On the conversion of squalene to lanosterol in vitro. J. Biol. Chem. 226: 921-930.
    • (1957) J. Biol. Chem. , vol.226 , pp. 921-930
    • Tchen, T.T.1    Bloch, K.2
  • 55
    • 0031574072 scopus 로고    scopus 로고
    • The ClustalX windows interface: Flexible strategies for multiple sequence alignment aided by quality analysis tools
    • THOMPSON, J. D., T. J. GIBSON, F. PLEWNIAK, F. JEANMOUGIN and D. G. HIGGINS, 1997 The ClustalX windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res. 24: 4876-4882.
    • (1997) Nucleic Acids Res. , vol.24 , pp. 4876-4882
    • Thompson, J.D.1    Gibson, T.J.2    Plewniak, F.3    Jeanmougin, F.4    Higgins, D.G.5
  • 56
    • 0028180320 scopus 로고
    • Suppression of activated Let-60 ras protein defines a role of Caenorhabditis elegans Sur-1 MAP kinase in vulval differentiation
    • WU, Y., and M. HAN, 1994 Suppression of activated Let-60 ras protein defines a role of Caenorhabditis elegans Sur-1 MAP kinase in vulval differentiation. Genes Dev. 8: 147-159.
    • (1994) Genes Dev. , vol.8 , pp. 147-159
    • Wu, Y.1    Han, M.2
  • 57
    • 0028943025 scopus 로고
    • MEK-2, a Caenorhabditis elegans MAP kinase kinase, functions in Ras-mediated vulval induction and other developmental events
    • WU, Y., M. HAN and K. L. GUAN, 1995 MEK-2, a Caenorhabditis elegans MAP kinase kinase, functions in Ras-mediated vulval induction and other developmental events. Genes Dev. 9: 742-755.
    • (1995) Genes Dev. , vol.9 , pp. 742-755
    • Wu, Y.1    Han, M.2    Guan, K.L.3
  • 58
    • 0024280244 scopus 로고
    • The Caenorhabditis elegans lin-12 gene encodes a transmembrane protein with overall similarity to Drosophila Notch
    • YOCHEM, J., K. WESTON and I. GREENWALD, 1988 The Caenorhabditis elegans lin-12 gene encodes a transmembrane protein with overall similarity to Drosophila Notch. Nature 335: 547-550.
    • (1988) Nature , vol.335 , pp. 547-550
    • Yochem, J.1    Weston, K.2    Greenwald, I.3
  • 59
    • 0031003117 scopus 로고    scopus 로고
    • Ras is required for a limited number of cell fates and not for general proliferation in Caenorhabditis elegans
    • YOCHEM, J., M. SUNDARAM and M. HAN, 1997 Ras is required for a limited number of cell fates and not for general proliferation in Caenorhabditis elegans. Mol. Cell. Biol. 17: 2716-2722.
    • (1997) Mol. Cell. Biol. , vol.17 , pp. 2716-2722
    • Yochem, J.1    Sundaram, M.2    Han, M.3
  • 60
    • 0842328578 scopus 로고    scopus 로고
    • Modulation of KSR activity in Caenorhabditis elegans by Zn ions, PAR-1 kinase and PP2A phosphatase
    • YODER, J. H., H. CHONG, K. L. GUAN and M. HAN, 2004 Modulation of KSR activity in Caenorhabditis elegans by Zn ions, PAR-1 kinase and PP2A phosphatase. EMBO J. 23: 111-119.
    • (2004) EMBO J. , vol.23 , pp. 111-119
    • Yoder, J.H.1    Chong, H.2    Guan, K.L.3    Han, M.4
  • 61
    • 0034682828 scopus 로고    scopus 로고
    • A novel human tocopherol-associated protein: Cloning, in vitro expression, and characterization
    • ZIMMER, S., A. STOCKER, M. N. SARBOLOUKI, S. E. SPYCHER, J. SASSOON et al., 2000 A novel human tocopherol-associated protein: cloning, in vitro expression, and characterization. J. Biol. Chem. 275: 25672-25680.
    • (2000) J. Biol. Chem. , vol.275 , pp. 25672-25680
    • Zimmer, S.1    Stocker, A.2    Sarbolouki, M.N.3    Spycher, S.E.4    Sassoon, J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.