Identification of a new cancer/testis gene family, CT47, among expressed multicopy genes on the human X chromosome

Genes Chromosomes and Cancer

Volumn 45, Issue 4, 2006, Pages 392-400

  Chen, Yao Tseng ^a,b,d   Iseli, Christian ^c   Yenditti, Charis A ^b   Old, Lloyd J ^b   Simpson, Andrew J G ^b   Jongeneel, C Victor ^c  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^c SWISS INSTITUTE OF BIOINFORMATICS   (Switzerland)

^d NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; GENE PRODUCT; GLUTAMIC ACID; MESSENGER RNA; PROTEIN CT47; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BREAST CANCER; CARBOXY TERMINAL SEQUENCE; CHIMPANZEE; CHROMOSOME MAP; CHROMOSOME XP; COLORECTAL CANCER; CT47 GENE; ESOPHAGUS CANCER; GENE; GENE ACTIVATION; GENE DUPLICATION; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; GENE LOCATION; GERM CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG CANCER; MULTIGENE FAMILY; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE HOMOLOGY; TESTIS; X CHROMOSOME;

CELL LINE, TUMOR; CHROMOSOMES, HUMAN, X; EXPRESSED SEQUENCE TAGS; FEMALE; GENE DOSAGE; GENE EXPRESSION PROFILING; GENES, NEOPLASM; HUMANS; MALE; MULTIGENE FAMILY; NEOPLASMS; PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TESTIS;

PAN TROGLODYTES;

EID: 33644756521     PISSN: 10452257     EISSN: 10982264     Source Type: Journal    
DOI: 10.1002/gcc.20298     Document Type: Article

References (21)

1. Artamonova, II, Gelfand MS. 2004. Evolution of the exon-intron structure and alternative splicing of the MAGE-A family of cancer/testis antigens. J Mol Evol 59:620-631.
2. Birney E, Andrews TD, Bevan P, Caccamo M, Chen Y, Clarke L, Coates G, Cuff J, Curwen V, Cutts T and others. 2004. An overview of Ensembl. Genome Res 14:925-928.
3. Boon T, van der Bruggen P. 1996. Human tumor antigens recognized by T lymphocytes. J Exp Med 183:725-729.
4. Chen YT, Scanlan MJ, Venditti CA, Chua R, Theiler G, Stevenson BJ, Iseli C, Gure AO, Vasicek T, Strausberg RL, Jongeneel CV, Old LJ, Simpson AJ. 2005. Identification of cancer/testis-antigen genes by massively parallel signature sequencing. Proc Natl Acad Sci USA 102:7940-7945.
5. Chomez P, De Backer O, Bertrand M, De Plaen E, Boon T, Lucas S. 2001. An overview of the MAGE gene family with the identification of all human members of the family. Cancer Res 61:5544-5551.
6. De Backer O, Arden KC, Boretti M, Vantomme V, De Smet C, Czekay S, Viars CS, De Plaen E, Brasseur F, Chomez P, Van den Eynde B, Boon T, van der Bruggen P. 1999. Characterization of the GAGE genes that are expressed in various human cancers and in normal testis. Cancer Res 59:3157-3165.
7. Dong XY, Su YR, Qian XP, Yang XA, Pang XW, Wu HY, Chen WF. 2003. Identification of two novel CT antigens and their capacity to elicit antibody response in hepatocellular carcinoma patients. Br J Cancer 89:291-297.
8. Florea L, Hartzell G, Zhang Z, Rubin GM, Miller W. 1998. A computer program for aligning a cDNA sequence with a genomic DNA sequence. Genome Res 8:967-974.
9. Gure AO, Stockert E, Arden KC, Boyer AD, Viars CS, Scanlan MJ, Old LJ, Chen YT. 2000. CT10: a new cancer-testis (CT) antigen homologous to CT7 and the MAGE family, identified by representational-difference analysis. Int J Cancer 85:726-732.
10. Cure AO, Wei IJ, Old LJ, Chen YT 2002. The SSX gene family: characterization of 9 complete genes. Int J Cancer 101:448-453.
11. Iseli C, Stevenson BJ, de Souza SJ, Samaia HB, Camargo AA, Buetow KH, Strausberg RL, Simpson AJ, Bucher P, Jongeneel CV. 2002. Long-range heterogeneity at the 3′ ends of human mRNAs. Genome Res 12:1068-1074.
12. Lucas S, De Plaen E, Boon T. 2000. MAGE-B5, MAGE-B6, MAGE-C2, and MAGE-C3: four new members of the MAGE family with tumor-specific expression. Int J Cancer 87:55-60.
13. Ross MT, Grafham DV, Coffey AJ, Scherer S, McLay K. Muzny D, Platzer M, Howell GR, Burrows C, Bird CP, Prankish A, Lovell FL, Howe KL, Ashurst JL, Fulton RS, Sudbrak R, Wen G, Jones MC, Hurles ME, Andrews TD, Scott CE, Searle S, Ramser J, Whittaker A, Deadman R, Carter NP, Hunt SE, Chen R, Cree A, Gunaratne P, Havlak P, Hodgson A, Metzker ML, Richards S, Scott G, Steffen D, Sodergren E, Wheeler DA, Worley KC, Ainscough R, Ambrose KD, Ansari-Lari MA, Aradhya S, Ashwell RI, Babbage AK, Bagguley CL, Ballabio A, Banerjee R, Barker GE, Barlow KF, Barrett IP, Bates KN, Beare DM, Beasley H, Beasley O, Beck A, Bethel G, Blechschmidt K, Brady N, Bray-Allen S, Bridgeman AM, Brown AJ, Brown MJ, Bonnin D, Bruford EA, Buhay C, Burch P, Burford D, Burgess J, Burrill W, Burton J, Bye JM, Carder C, Carrel L, Chako J, Chapman JC, Chavez D, Chen E, Chen G, Chen Y, Chen Z, Chinault C, Ciccodicola A, Clark SY, Clarke G, Clee CM, Clegg S, Clerc-Blankenburg K, Clifford K, Cobley V, Cole CG, Conquer JS, Corby N, Connor RE, David R, Davies J, Davis C, Davis J, Delgado O, Deshazo D, Dhami P, Ding Y, Dinh H, Dodsworth S, Draper H, Dugan-Rocha S, Dunham A, Dunn M, Durbin KJ, Dutta I, Eades T, Ellwood M, Emery-Cohen A, Errington H, Evans KL, Faulkner L, Francis F, Frankland J, Fraser AE, Galgoczy P, Gilbert J, Gill R, Glockner G, Gregory SG, Gribble S, Griffiths C, Grocock R, Gu Y, Gwilliam R, Hamilton C, Hart EA, Hawes A, Heath PD, Heitmann K, Hennig S, Hernandez J, Hinzmann B, Ho S, Hoffs M, Howden PJ, Huckle EJ, Hume J, Hunt PJ, Hunt AR, Isherwood J, Jacob L, Johnson D, Jones S, de Jong PJ, Joseph SS, Keenan S, Kelly S, Kershaw JK, Khan Z, Kioschis P, Klages S, Knights AJ, Kosiura A, Kovar-Smith C, Laird GK, Langford C, Lawlor S, Leversha M, Lewis L, Liu W, Lloyd C, Lloyd DM, Loulseged H, Loveland JE, Lovell JD, Lozado R, Lu J, Lyne R, Ma J, Maheshwari M, Matthews LH, McDowall J, McLaren S, McMurray A, Meidl R Meitinger T, Milne S, Miner G, Mistry SL, Morgan M, Morris S, Muller I, Mullikin JC, Nguyen N, Nordsiek G, Nyakatura G, O'Dell CN, Okwuonu G, Palmer S, Pandian R, Parker D, Parrish J, Pasternak S, Patel D, Pearce AV, Pearson DM, Pelan SE, Perez L, Porter KM, Ramsey Y, Reichwald K, Rhodes S, Ridler KA, Schlessinger D, Schueler MG, Sehra HK, Shaw-Smith C, Shen H, Sheridan EM, Shownkeen R, Skuce CD, Smith ML, Sotheran EC, Steingruber HE, Steward CA, Storey R, Swann RM, Swarbreck D, Tabor PE, Taudien S, Taylor T, Teague B, Thomas K, Thorpe A, Timms K, Tracey A, Trevanion S, Tromans AC, d'Urso M, Verduzco D, Villasana D, Waldron L, Wall M, Wang Q, Warren J, Warry GL, Wei X, West A, Whitehead SL, Whiteley MN, Wilkinson JE, Willey DL, Williams G, Williams L, Williamson A, Williamson H, Wilming L, Woodmansey RL, Wray PW, Yen J, Zhang J, Zhou J, Zoghbi H, Zorilla S, Buck D, Reinhardt R, Poustka A, Rosenthal A, Lehrach H, Meindl A, Minx PJ, Hillier LW, Willard HF, Wilson RK, Waterston RH, Rice CM, Vaudin M, Coulson A, Nelson DL, Weinstock G, Sulston JE, Durbin R, Hubbard T, Gibbs RA, Beck S, Rogers J, Bentley DR. 2005. The DNA sequence of the human X chromosome. Nature 434:325-337.
14. Sahin U, Tureci O, Schmitt H, Cochlovius B, Johannes T, Schmits R, Stenner F, Luo G, Schobert I, Pfreundschuh M. 1995. Human neoplasms elicit multiple specific immune responses in the autologous host. Proc Natl Acad Sci USA 92:11810-11813.
15. Scanlan MJ, Gordon CM, Williamson B, Lee SY, Chen YT, Stockert E, Jungbluth A, Ritter G, Jager D, Jager E. Knuth A, Old LJ. 2002a. Identification of cancer/testis genes by database mining and mRNA expression analysis. Int J Cancer 98:485-492.
16. Scanlan MJ, Gure AO, Jungbluth AA, Old LJ, Chen YT. 2002b. Cancer/testis antigens: an expanding family of targets for cancer immunotherapy. Immunol Rev 188:22-32.
17. Scanlan MJ, Simpson AJG, Old LJ. 2004. The cancer/testis genes: review, standardization, and commentary. Cancer Immunity 4:1.
18. Searle SM, Gilbert J, Iyer V, Clamp M. 2004. The otter annotation system. Genome Res 14:963-970.
19. Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, Mc-Ewan PJ, McKernan KJ, Malek JA, Gunaratne PH. Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA;Mammalian Gene Collection Program Team. 2002. Generation and initial analysis of more than-15, 000 full-length human and mouse cDNA sequences. Proc Natl Acad Sci USA 99:16899-16903.
20. Warburton PE, Giordano J, Cheung F, Gelfand Y, Benson G. 2004. Inverted repeat structure of the human genome: the X-chromosome contains a preponderance of large, highly homologous inverted repeats that contain testes genes. Genome Res 14:1861-1869.
21. Zhang Z, Schwartz S, Wagner L, Miller W. 2000. A greedy algorithm for aligning DNA sequences. J Comput Biol 7:203-214.